The Oncosearch | Oncotarget

Reg4 and its downstream transcriptional activator CD44ICD in stage II and III colorectal cancer Research Paper

Jared A. Sninsky, Kumar S. Bishnupuri, Iván González, Nikolaos A. Trikalinos, Ling Chen, Brian K. Dieckgraefe

Published Feb 8, 2021 · Vol. 12, No. 4 · pp. 278-291

Keywords: Reg4, CD44, CD44ICD, colorectal cancer

Low concentrations of vorinostat decrease EB1 expression in GBM cells and affect microtubule dynamics, cell survival and migration Research Paper

Thomas Perez, Raphaël Bergès, Hélène Maccario, Sarah Oddoux, Stéphane Honoré

Published Feb 5, 2021 · Vol. 12, No. 4 · pp. 304-315

Keywords: vorinostat, glioblastoma, EB1, microtubule, tubulin

Cancer stem cells and macrophages: molecular connections and future perspectives against cancer Review

Beatrice Aramini, Valentina Masciale, Giulia Grisendi, Federico Banchelli, Roberto D’Amico, Antonino Maiorana, Uliano Morandi, Massimo Dominici, Khawaja Husnain Haider

Published Jan 27, 2021 · Vol. 12, No. 3 · pp. 230-250

Keywords: cancer stem cells, macrophages, future perspectives, cancer, target treatments

High mRNA expression of LY6 gene family is associated with overall survival outcome in pancreatic ductal adenocarcinoma Research Paper

Eric Russ, Krithika Bhuvaneshwar, Guisong Wang, Benjamin Jin, Michele M. Gage, Subha Madhavan, Yuriy Gusev, Geeta Upadhyay

Published Jan 26, 2021 · Vol. 12, No. 3 · pp. 145-159

Keywords: LY6 genes, pancreatic cancer, immune cells, survival outcome

Head to head evaluation of second generation ALK inhibitors brigatinib and alectinib as first-line treatment for ALK+ NSCLC using an in silico systems biology-based approach Research Paper

Enric Carcereny, Alonso Fernández-Nistal, Araceli López, Carmen Montoto, Andrea Naves, Cristina Segú-Vergés, Mireia Coma, Guillem Jorba, Baldomero Oliva, Jose Manuel Mas

Published Jan 22, 2021 · Vol. 12, No. 4 · pp. 316-332

Keywords: ALK inhibitor, brigatinib, alectinib, mathematical model, systems biology

Introducing Oncoscience: from Oncotarget to the future News

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Published Jan 12, 2021 · Vol. 0, No. 13

Clinical application of liquid biopsies to detect somatic BRCA1/2 mutations and guide potential therapeutic intervention for patients with metastatic breast cancer Research Perspective

Neelima Vidula, Leif W. Ellisen, Aditya Bardia

Published Dec 28, 2020 · Vol. 12, No. 2 · pp. 63-65

Keywords: cell-free DNA, BRCA1/2, PARP inhibitor, metastatic breast cancer, plasma based genotyping

Comparative genomic analysis of primary tumors and paired brain metastases in lung cancer patients by whole exome sequencing: a pilot study Research Paper

Pascale Tomasini, Fabrice Barlesi, Sophie Gilles, Isabelle Nanni-Metellus, Riccardo Soffietti, Emilie Denicolai, Eric Pellegrino, Emilie Bialecki, L’Houcine Ouafik, Philippe Metellus

Published Nov 27, 2020 · Vol. 11, No. 50 · pp. 4648-4654

Keywords: lung cancer, brain metastasis, whole exome sequencing, comparison, mutations

A comprehensive analysis of clinical trials in pancreatic cancer: what is coming down the pike? Research Paper

Erryk S. Katayama, Jonathan J. Hue, David L. Bajor, Lee M. Ocuin, John B. Ammori, Jeffrey M. Hardacre, Jordan M. Winter

Published Aug 24, 2020 · Vol. 11, No. 38 · pp. 3489-3501

Keywords: pancreatic cancer, pancreatic ductal adenocarcinoma, clinical trial, novel treatment, drug development

Exosomes secreted under hypoxia enhance stemness in Ewing’s sarcoma through miR-210 delivery Research Paper

Matthew J. Kling, Nagendra K. Chaturvedi, Varun Kesherwani, Don W. Coulter, Timothy R. McGuire, J. Graham Sharp, Shantaram S. Joshi

Published Jul 30, 2020 · Vol. 11, No. 40 · pp. 3633-3645

Keywords: exosomes, hypoxia, Ewing’s sarcoma, stemness, miR-210

Losartan improves the therapeutic effect of metronomic cyclophosphamide in triple negative mammary cancer models Research Paper

Leandro E. Mainetti, María José Rico, Cintia Daniela Kaufman, Monica Carolina Grillo, Julian Guercetti, María Virginia Baglioni, Antonela Del Giúdice, Maria Celeste Capitani, Matias Fusini, Viviana Rosa Rozados, O. Graciela Scharovsky

Published Jul 22, 2020 · Vol. 11, No. 32 · pp. 3048-3060

Keywords: mammary cancer, metronomic chemotherapy, drug repurposing, cyclophosphamide, losartan

Development and characterization of the novel human osteosarcoma cell line COS-33 with sustained activation of the mTOR pathway Research Paper

Ashley VanCleave, Mykayla Palmer, Fang Fang, Haydee Torres, Tania Rodezno, Qilin Li, Kirby Fuglsby, Claire Evans, Yohannes Afeworki, Alan Ross, Pulivarthi Rao, Patricia Leiferman, Siyuan Zheng, Peter Houghton, Jianning Tao

Published May 18, 2020 · Vol. 11, No. 27 · pp. 2597-2610

Keywords: osteosarcoma, COS-33, mTOR, osteogenic differentiation, TP53

The role of EGFR mutations in predicting recurrence in early and locally advanced lung adenocarcinoma following definitive therapy Research Paper

Carlos Galvez, Saya Jacob, Brian S. Finkelman, Jeffrey Zhao, Kyle Tegtmeyer, Young Kwang Chae, Nisha Mohindra, Ravi Salgia, Borko Jovanovic, Amir Behdad, Victoria Villaflor

Published May 6, 2020 · Vol. 11, No. 21 · pp. 1953-1960

Keywords: non-small cell lung cancer, lung adenocarcinoma, EGFR, early, recurrence

CD44+/EPCAM+ cells detect a subpopulation of ALDH^high cells in human non-small cell lung cancer: A chance for targeting cancer stem cells? Research Paper

Valentina Masciale, Giulia Grisendi, Federico Banchelli, Roberto D’Amico, Antonino Maiorana, Pamela Sighinolfi, Alessandro Stefani, Uliano Morandi, Massimo Dominici, Beatrice Aramini

Published Apr 16, 2020 · Vol. 11, No. 17 · pp. 1545-1555

Keywords: immunophenotype, cancer stem cells, cancer stem-like cells, non-small cell lung cancer (NSCLC), target therapy

Novel plant microRNAs from broccoletti sprouts do not show cross-kingdom regulation of pancreatic cancer Research Paper

Xi Xiao, Carsten Sticht, Libo Yin, Li Liu, Svetlana Karakhanova, Yefeng Yin, Christina Georgikou, Jury Gladkich, Wolfgang Gross, Norbert Gretz, Ingrid Herr

Published Apr 7, 2020 · Vol. 11, No. 14 · pp. 1203-1217

Keywords: broccoli, broccoletti, Brassica rapa sylvestris, plant microRNAs, cross-kingdom regulation

A phase II randomized clinical trial using aglycone isoflavones to treat patients with localized prostate cancer in the pre-surgical period prior to radical prostatectomy Research Paper

Nagi B. Kumar, Julio Pow-Sang, Philippe Spiess, Shohreh Dickinson, Michael J. Schell

Published Apr 7, 2020 · Vol. 11, No. 14 · pp. 1218-1234

Keywords: isoflavones, chemoprevention, prostate cancer, African American men, Caucasian men

The prognostic role of microRNA in epithelial ovarian cancer: a systematic review of literature with an overall survival meta-analysis Review

Patricia Ferreira, Rosimeire Aparecida Roela, Rossana Veronica Mendoza Lopez, Maria Del Pilar Estevez-Diz

Published Mar 24, 2020 · Vol. 11, No. 12 · pp. 1085-1095

Keywords: ovarian cancer, microRNA, miRNA, prognostic factors, overall survival

Immune system and bone microenvironment: rationale for targeted cancer therapies Review

Gnoni Antonio, Brunetti Oronzo, Longo Vito, Calabrese Angela, Argentiero Antonel-la, Calbi Roberto, Solimando Antonio Giovanni, Licchetta Antonella

Published Jan 28, 2020 · Vol. 11, No. 4 · pp. 480-487

Keywords: antiandrogens, bisphosphonates, bone niche, immune system, osteoimmunology

The virome of HPV-positive tonsil squamous cell carcinoma and neck metastasis Research Paper

Ryan M. Carey, Karthik Rajasekaran, Tyler Seckar, Xiang Lin, Zhi Wei, Charles C.L. Tong, Viran J. Ranasinghe, Jason G. Newman, Bert W. O'Malley Jr., Gregory S. Weinstein, Michael D. Feldman, Erle S. Robertson

Published Jan 21, 2020 · Vol. 11, No. 3 · pp. 282-293

Keywords: HPV, cancer, virus, virome, oropharyngeal squamous cell carcinoma

Head and neck squamous cancer progression is marked by CLIC4 attenuation in tumor epithelium and reciprocal stromal upregulation of miR-142-3p, a novel post-transcriptional regulator of CLIC4 Research Paper

Brandi L. Carofino, Kayla M. Dinshaw, Pui Yan Ho, Christophe Cataisson, Aleksandra M. Michalowski, Andrew Ryscavage, Addie Alkhas, Nathan W. Wong, Vishal Koparde, Stuart H. Yuspa

Published Dec 31, 2019 · Vol. 10, No. 68 · pp. 7251-7275

Keywords: in situ hybridization, single-cell RNA-sequencing, stroma, miRNA, immune infiltration

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Reg4 and its downstream transcriptional activator CD44ICD in stage II and III colorectal cancer Research Paper

Low concentrations of vorinostat decrease EB1 expression in GBM cells and affect microtubule dynamics, cell survival and migration Research Paper

Cancer stem cells and macrophages: molecular connections and future perspectives against cancer Review

High mRNA expression of LY6 gene family is associated with overall survival outcome in pancreatic ductal adenocarcinoma Research Paper

Head to head evaluation of second generation ALK inhibitors brigatinib and alectinib as first-line treatment for ALK+ NSCLC using an in silico systems biology-based approach Research Paper

Introducing Oncoscience: from Oncotarget to the future News

Clinical application of liquid biopsies to detect somatic BRCA1/2 mutations and guide potential therapeutic intervention for patients with metastatic breast cancer Research Perspective

Comparative genomic analysis of primary tumors and paired brain metastases in lung cancer patients by whole exome sequencing: a pilot study Research Paper

A comprehensive analysis of clinical trials in pancreatic cancer: what is coming down the pike? Research Paper

Exosomes secreted under hypoxia enhance stemness in Ewing’s sarcoma through miR-210 delivery Research Paper

Losartan improves the therapeutic effect of metronomic cyclophosphamide in triple negative mammary cancer models Research Paper

Development and characterization of the novel human osteosarcoma cell line COS-33 with sustained activation of the mTOR pathway Research Paper

The role of EGFR mutations in predicting recurrence in early and locally advanced lung adenocarcinoma following definitive therapy Research Paper

CD44+/EPCAM+ cells detect a subpopulation of ALDH^high cells in human non-small cell lung cancer: A chance for targeting cancer stem cells? Research Paper

Novel plant microRNAs from broccoletti sprouts do not show cross-kingdom regulation of pancreatic cancer Research Paper

A phase II randomized clinical trial using aglycone isoflavones to treat patients with localized prostate cancer in the pre-surgical period prior to radical prostatectomy Research Paper

The prognostic role of microRNA in epithelial ovarian cancer: a systematic review of literature with an overall survival meta-analysis Review

Immune system and bone microenvironment: rationale for targeted cancer therapies Review

The virome of HPV-positive tonsil squamous cell carcinoma and neck metastasis Research Paper

Head and neck squamous cancer progression is marked by CLIC4 attenuation in tumor epithelium and reciprocal stromal upregulation of miR-142-3p, a novel post-transcriptional regulator of CLIC4 Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Reg4 and its downstream transcriptional activator CD44ICD in stage II and III colorectal cancer Research Paper

Low concentrations of vorinostat decrease EB1 expression in GBM cells and affect microtubule dynamics, cell survival and migration Research Paper

Cancer stem cells and macrophages: molecular connections and future perspectives against cancer Review

High mRNA expression of LY6 gene family is associated with overall survival outcome in pancreatic ductal adenocarcinoma Research Paper

Head to head evaluation of second generation ALK inhibitors brigatinib and alectinib as first-line treatment for ALK+ NSCLC using an in silico systems biology-based approach Research Paper

Introducing Oncoscience: from Oncotarget to the future News

Clinical application of liquid biopsies to detect somatic BRCA1/2 mutations and guide potential therapeutic intervention for patients with metastatic breast cancer Research Perspective

Comparative genomic analysis of primary tumors and paired brain metastases in lung cancer patients by whole exome sequencing: a pilot study Research Paper

A comprehensive analysis of clinical trials in pancreatic cancer: what is coming down the pike? Research Paper

Exosomes secreted under hypoxia enhance stemness in Ewing’s sarcoma through miR-210 delivery Research Paper

Losartan improves the therapeutic effect of metronomic cyclophosphamide in triple negative mammary cancer models Research Paper

Development and characterization of the novel human osteosarcoma cell line COS-33 with sustained activation of the mTOR pathway Research Paper

The role of EGFR mutations in predicting recurrence in early and locally advanced lung adenocarcinoma following definitive therapy Research Paper

CD44+/EPCAM+ cells detect a subpopulation of ALDHhigh cells in human non-small cell lung cancer: A chance for targeting cancer stem cells? Research Paper

Novel plant microRNAs from broccoletti sprouts do not show cross-kingdom regulation of pancreatic cancer Research Paper

A phase II randomized clinical trial using aglycone isoflavones to treat patients with localized prostate cancer in the pre-surgical period prior to radical prostatectomy Research Paper

The prognostic role of microRNA in epithelial ovarian cancer: a systematic review of literature with an overall survival meta-analysis Review

Immune system and bone microenvironment: rationale for targeted cancer therapies Review

The virome of HPV-positive tonsil squamous cell carcinoma and neck metastasis Research Paper

Head and neck squamous cancer progression is marked by CLIC4 attenuation in tumor epithelium and reciprocal stromal upregulation of miR-142-3p, a novel post-transcriptional regulator of CLIC4 Research Paper

CD44+/EPCAM+ cells detect a subpopulation of ALDH^high cells in human non-small cell lung cancer: A chance for targeting cancer stem cells? Research Paper