The Oncosearch | Oncotarget

NF-κB over-activation portends improved outcomes in HPV-associated head and neck cancer Research Paper

Travis P. Schrank, Andrew C. Prince, Tejas Sathe, Xiaowei Wang, Xinyi Liu, Damir T. Alzhanov, Barbara Burtness, Albert S. Baldwin, Wendell G. Yarbrough, Natalia Issaeva

Published May 7, 2022 · Vol. 13, No. 1 · pp. 707-722

Keywords: HPV, head and neck cancer, CYLD, TRAF3, NF-κB

Exploring the synergistic effects of cabozantinib and a programmed cell death protein 1 inhibitor in metastatic renal cell carcinoma with machine learning Research Paper

Ignacio Durán, Daniel Castellano, Javier Puente, Lidia Martín-Couce, Esther Bello, Urbano Anido, José Manuel Mas, Luis Costa

Published Jan 20, 2022 · Vol. 13, No. 1 · pp. 237-256

Keywords: machine learning, cabozantinib, renal cell carcinoma, tumour microenvironment, systems biology

Early detection of treatment futility in patients with metastatic colorectal cancer Research Paper

Jodi I. Rattner, Karen A. Kopciuk, Hans J. Vogel, Patricia A. Tang, Jeremy D. Shapiro, Dongsheng Tu, Derek J. Jonker, Lillian L. Siu, Chris J. O’Callaghan, Oliver F. Bathe

Published Dec 21, 2021 · Vol. 13, No. 1 · pp. 61-72

Keywords: colorectal cancer, metabolomics, response biomarkers, radiographic imaging, chemotherapy

Excitement for our future News

John L. Marshall

Published Nov 2, 2021 · Vol. 12, No. 23 · pp. 2307-2307

Keywords: multi-omics, molecular signatures, BRCA

A high-throughput customized cytokinome screen of colon cancer cell responses to small-molecule oncology drugs Research Paper

Kelsey E. Huntington, Anna Louie, Lanlan Zhou, Wafik S. El-Deiry

Published Sep 11, 2021 · Vol. 12, No. 20 · pp. 1980-1991

Keywords: cytokine profiling, inflammatory response, chemokine, growth factor, immune profiling

Inhibition of the MAP2K7-JNK pathway with 5Z-7-oxozeaenol induces apoptosis in T-cell acute lymphoblastic leukemia Research Paper

Taylor J. Chen, Wa Du, Jacob J. Junco, Cory Seth Bridges, Ye Shen, Monica Puppi, Karen R. Rabin, H. Daniel Lacorazza

Published Jul 31, 2021 · Vol. 12, No. 18 · pp. 1787-1801

Keywords: T-ALL, MAP2K7, 5z-7-oxozeaenol

Role of microRNAs in glioblastoma Review

Ming Chen, Zdravka Medarova, Anna Moore

Published Jul 30, 2021 · Vol. 12, No. 17 · pp. 1707-1723

Keywords: glioblastoma, microRNA, miRNA-based therapies, miRNA delivery

Scent test using Caenorhabditis elegans to screen for early-stage pancreatic cancer Research Paper

Ayumu Asai, Masamitsu Konno, Miyuki Ozaki, Koichi Kawamoto, Ryota Chijimatsu, Nobuaki Kondo, Takaaki Hirotsu, Hideshi Ishii

Published Jul 28, 2021 · Vol. 12, No. 17 · pp. 1687-1696

Keywords: Caenorhabditis elegans, early-stage pancreatic cancer, scent test, biomarker, diagnosis

Clinicopathological utility of human epidermal growth factor receptor 2 (HER2)-heterogeneity for next-generation treatments of triple-negative breast cancer Editorial

Sasagu Kurozumi, Ayaka Katayama, Ken Shirabe, Jun Horiguchi, Emad A. Rakha

Published Jun 19, 2021 · Vol. 12, No. 22 · pp. 2302-2304

Keywords: breast cancer, HER2 low, triple negative, heterogeneity

Future directions for immunotherapy in meningioma treatment Editorial

John W. Rutland, Jonathan T. Dullea, Raj K. Shrivastava

Published Jun 12, 2021 · Vol. 12, No. 22 · pp. 2300-2301

Keywords: meningioma, immunotherapy, molecular genetics

Association of high-sensitivity C-reactive protein and odds of breast cancer by molecular subtype: analysis of the MEND study Research Paper

Anjali Gupta, Taofik Oyekunle, Omolola Salako, Adetola Daramola, Olusegun Alatise, Gabriel Ogun, Adewale Adeniyi, April Deveaux, Veeral Saraiya, Allison Hall, Omobolaji Ayandipo, Thomas Olajide, Olalekan Olasehinde, Olukayode Arowolo, Adewale Adisa, Oludolapo Afuwape, Aralola Olusanya, Aderemi Adegoke, Trygve O. Tollefsbol, Donna Arnett, Michael J. Muehlbauer, Christopher B. Newgard, H3 Africa Kidney Research Network, Tomi Akinyemiju

Published Jun 10, 2021 · Vol. 12, No. 13 · pp. 1230-1242

Keywords: C-reactive protein, breast cancer, Nigeria, molecular subtype, menopausal status

Targeting cancer stem cells via integrin β4 Research Perspective

Hannah E. Dobson, Shasha Ruan, Alfred E. Chang, Max S. Wicha, Qiao Li

Published May 21, 2021 · Vol. 12, No. 18 · pp. 1850-1858

Keywords: cancer stem cells, ITGβ4, dendritic cell vaccine, bispecific antibody, T cells

Developing next generation immunomodulatory drugs and their combinations in multiple myeloma Research Perspective

Anjan Thakurta, William E. Pierceall, Michael D. Amatangelo, Erin Flynt, Amit Agarwal

Published May 19, 2021 · Vol. 12, No. 15 · pp. 1555-1563

Keywords: multiple myeloma, combinations, immunomodulatory agents, apoptosis, protein degradation

The acylfulvene alkylating agent, LP-184, retains nanomolar potency in non-small cell lung cancer carrying otherwise therapy-refractory mutations Research Paper

Aditya Kulkarni, Joseph Ryan McDermott, Umesh Kathad, Rama Modali, Jean-Philippe Richard, Panna Sharma, Kishor Bhatia

Published Apr 5, 2021 · Vol. 12, No. 8 · pp. 791-806

Keywords: non-small cell lung cancer, acylfulvene, alkylating agent, PTGR1, LP-184

Targeting cancer associated fibroblasts to enhance immunotherapy: emerging strategies and future perspectives Research Perspective

Christopher J. Hanley, Gareth J. Thomas

Published Mar 30, 2021 · Vol. 12, No. 14 · pp. 1427-1433

Keywords: tumour microenvironment, cancer associated fibroblasts, immunotherapy

Predicting clinical outcomes using cancer progression associated signatures Research Paper

Jared Mamrot, Nathan E. Hall, Robyn A. Lindley

Published Mar 30, 2021 · Vol. 12, No. 8 · pp. 845-858

Keywords: innate immunity, biomarker, mutagenesis, oncogenesis, cancer progression

Prognostic and therapeutic value of the Hippo pathway, RABL6A, and p53-MDM2 axes in sarcomas Research Paper

Chandni Desai, Jon Thomason, Jordan L. Kohlmeyer, Anna C. Reisetter, Parmanand Ahirwar, Khadijeh Jahanseir, Mariah Leidinger, Georgina Ofori-Amanfo, Karen Fritchie, Sadanandan E. Velu, Patrick Breheny, Dawn E. Quelle, Munir R. Tanas

Published Mar 21, 2021 · Vol. 12, No. 8 · pp. 740-755

Keywords: sarcoma, YAP, TAZ, p53-MDM2, RABL6A

Differential expression of Vitamin D binding protein in thyroid cancer health disparities Research Paper

Brittany Mull, Ryan Davis, Iqbal Munir, Mia C. Perez, Alfred A. Simental, Salma Khan

Published Mar 12, 2021 · Vol. 12, No. 7 · pp. 596-607

Keywords: DBP, thyroid cancer, health disparities

Mutually exclusive lymphangiogenesis or perineural infiltration in human skin squamous-cell carcinoma Research Paper

Julien Schaller, Hélène Maby-El Hajjami, Sylvie Rusakiewicz, Kalliopi Ioannidou, Nathalie Piazzon, Alexandra Miles, Déla Golshayan, Olivier Gaide, Daniel Hohl, Daniel E. Speiser, Karin Schaeuble

Published Mar 5, 2021 · Vol. 12, No. 7 · pp. 638-648

Keywords: lymphatic vessel, CD8+ T cell, perineural infiltration, skin squamous-cell carcinoma, tumor immunology

Characterization of the inflammatory microenvironment and hepatic macrophage subsets in experimental hepatocellular carcinoma models Research Paper

Helena Degroote, Sander Lefere, Astrid Vandierendonck, Bart Vanderborght, Tim Meese, Filip Van Nieuwerburgh, Xavier Verhelst, Anja Geerts, Hans Van Vlierberghe, Lindsey Devisscher

Published Feb 20, 2021 · Vol. 12, No. 6 · pp. 562-577

Keywords: hepatocellular carcinoma, macrophage subsets, tumor microenvironment, tumor associated macrophages, inflammation

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NF-κB over-activation portends improved outcomes in HPV-associated head and neck cancer Research Paper

Exploring the synergistic effects of cabozantinib and a programmed cell death protein 1 inhibitor in metastatic renal cell carcinoma with machine learning Research Paper

Early detection of treatment futility in patients with metastatic colorectal cancer Research Paper

Excitement for our future News

A high-throughput customized cytokinome screen of colon cancer cell responses to small-molecule oncology drugs Research Paper

Inhibition of the MAP2K7-JNK pathway with 5Z-7-oxozeaenol induces apoptosis in T-cell acute lymphoblastic leukemia Research Paper

Role of microRNAs in glioblastoma Review

Scent test using Caenorhabditis elegans to screen for early-stage pancreatic cancer Research Paper

Clinicopathological utility of human epidermal growth factor receptor 2 (HER2)-heterogeneity for next-generation treatments of triple-negative breast cancer Editorial

Future directions for immunotherapy in meningioma treatment Editorial

Association of high-sensitivity C-reactive protein and odds of breast cancer by molecular subtype: analysis of the MEND study Research Paper

Targeting cancer stem cells via integrin β4 Research Perspective

Developing next generation immunomodulatory drugs and their combinations in multiple myeloma Research Perspective

The acylfulvene alkylating agent, LP-184, retains nanomolar potency in non-small cell lung cancer carrying otherwise therapy-refractory mutations Research Paper

Targeting cancer associated fibroblasts to enhance immunotherapy: emerging strategies and future perspectives Research Perspective

Predicting clinical outcomes using cancer progression associated signatures Research Paper

Prognostic and therapeutic value of the Hippo pathway, RABL6A, and p53-MDM2 axes in sarcomas Research Paper

Differential expression of Vitamin D binding protein in thyroid cancer health disparities Research Paper

Mutually exclusive lymphangiogenesis or perineural infiltration in human skin squamous-cell carcinoma Research Paper

Characterization of the inflammatory microenvironment and hepatic macrophage subsets in experimental hepatocellular carcinoma models Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

NF-κB over-activation portends improved outcomes in HPV-associated head and neck cancer Research Paper

Exploring the synergistic effects of cabozantinib and a programmed cell death protein 1 inhibitor in metastatic renal cell carcinoma with machine learning Research Paper

Early detection of treatment futility in patients with metastatic colorectal cancer Research Paper

Excitement for our future News

A high-throughput customized cytokinome screen of colon cancer cell responses to small-molecule oncology drugs Research Paper

Inhibition of the MAP2K7-JNK pathway with 5Z-7-oxozeaenol induces apoptosis in T-cell acute lymphoblastic leukemia Research Paper

Role of microRNAs in glioblastoma Review

Scent test using Caenorhabditis elegans to screen for early-stage pancreatic cancer Research Paper

Clinicopathological utility of human epidermal growth factor receptor 2 (HER2)-heterogeneity for next-generation treatments of triple-negative breast cancer Editorial

Future directions for immunotherapy in meningioma treatment Editorial

Association of high-sensitivity C-reactive protein and odds of breast cancer by molecular subtype: analysis of the MEND study Research Paper

Targeting cancer stem cells via integrin β4 Research Perspective

Developing next generation immunomodulatory drugs and their combinations in multiple myeloma Research Perspective

The acylfulvene alkylating agent, LP-184, retains nanomolar potency in non-small cell lung cancer carrying otherwise therapy-refractory mutations Research Paper

Targeting cancer associated fibroblasts to enhance immunotherapy: emerging strategies and future perspectives Research Perspective

Predicting clinical outcomes using cancer progression associated signatures Research Paper

Prognostic and therapeutic value of the Hippo pathway, RABL6A, and p53-MDM2 axes in sarcomas Research Paper

Differential expression of Vitamin D binding protein in thyroid cancer health disparities Research Paper

Mutually exclusive lymphangiogenesis or perineural infiltration in human skin squamous-cell carcinoma Research Paper

Characterization of the inflammatory microenvironment and hepatic macrophage subsets in experimental hepatocellular carcinoma models Research Paper