The Oncosearch | Oncotarget

Altered glycosylation of MUC1 influences its association with CIN85: the role of this novel complex in cancer cell invasion and migration Research Paper

Sandra Cascio, Adam M Farkas, Rebecca P Hughey, Olivera J Finn

Published Sep 7, 2013 · Vol. 4, No. 10 · pp. 1686-1697

Keywords: MUC1, CIN85, protein-protein interaction, cell migration, metastasis, novel targets, glycosylation

DHH-RHEBL1 fusion transcript: a novel recurrent feature in the new landscape of pediatric CBFA2T3-GLIS2-positive acute myeloid leukemia Research Paper

Riccardo Masetti, Marco Togni, Annalisa Astolfi, Martina Pigazzi, Elena Manara, Valentina Indio, Carmelo Rizzari, Sergio Rutella, Giuseppe Basso, Andrea Pession, Franco Locatelli

Published Sep 7, 2013 · Vol. 4, No. 10 · pp. 1712-1720

Keywords: pediatric acute myeloid leukemia, citogenetically normal acute myeloid leuekemia, whole-transcriptome massively parallel sequencing, CBFA2T3-GLIS2 fusion transcript, DHH-RHEBL1 fusion transcript.

Dietary restriction-resistant human tumors harboring the PIK3CA-activating mutation H1047R are sensitive to metformin Research Paper

Silvia Cufi, Bruna Corominas-Faja, Eugeni Lopez-Bonet, Rosa Bonavia, Sonia Pernas, Isabel Alvarez Lopez, Joan Dorca, Susana Martinez, Norberto Batista Lopez, Severina Dominguez Martinez, Elisabet Cuyas, Joana Visa, Esther Rodriguez-Gallego, Rosa Quirantes-Pine, Antonio Segura-Carretero, Jorge Joven, Begona Martin-Castillo, Javier A Menendez

Published Aug 21, 2013 · Vol. 4, No. 9 · pp. 1484-1495

Keywords: Metformin, cancer, PI3K, PIK3CA mutations, dietary restriction, calorie restriction, rapamycin

Increased expression and copy number amplification of LINE-1 and SINE B1 retrotransposable elements in murine mammary carcinoma progression Research Paper

Alberto Gualtieri, Federica Andreola, Ilaria Sciamanna, Paola Sinibaldi Vallebona, Annalucia Serafino, Corrado Spadafora

Published Aug 9, 2013 · Vol. 4, No. 11 · pp. 1882-1893

Keywords: LINE-1 retrotransposons, SINE retrotransposons, reverse transcriptase, copy number amplification, breast cancer progression

Tumor suppressor genes promote rhabdomyosarcoma progression in p53 heterozygous, HER-2/neu transgenic mice Research Paper

Marianna L Ianzano, Stefania Croci, Giordano Nicoletti, Arianna Palladini, Lorena Landuzzi, Valentina Grosso, Dario Ranieri, Massimiliano Dall'Ora, Ilaria Santeramo, Milena Urbini, Carla De Giovanni, Pier Luigi Lollini, Patrizia Nanni

Published Aug 6, 2013 · Vol. 5, No. 1 · pp. 108-119

Keywords: rhabdomyosarcoma, p53, HER-2, p19Arf, p21Cip1

Crucial Role for Early Growth Response-1 in the Transcriptional Regulation of miR-20b in Breast Cancer Research Paper

Dongping Li, Yaroslav Ilnytskyy, Anna Kovalchuk, Levon M. Khachigian, Roderick T. Bronson, Bo Wang, Olga Kovalchuk

Published Jul 28, 2013 · Vol. 4, No. 9 · pp. 1373-1387

Keywords: EGR1, miR-20b, transcription, PTEN, BRCA1, breast cancer, proliferation, migration, cell cycle arrest

Targeting mixed lineage kinases in ER-positive breast cancer cells leads to G2/M cell cycle arrest and apoptosis. Research Paper

Limin Wang, Kathleen A Gallo, Susan E Conrad

Published Jul 7, 2013 · Vol. 4, No. 8 · pp. 1158-1171

Keywords: breast cancer, kinase inhibitors, cell cycle, apoptosis

Brain Tumor Stem Cell Multipotency Correlates with Nanog Expression and Extent of Passaging in Human Glioblastoma Xenografts Research Paper

Dominique M. Higgins, Ruisi Wang, Brian Milligan, Mark Schroeder, Brett Carlson, Jenny Pokorny, Samuel H. Cheshier, Fredric B. Meyer, Irving L. Weissman, Jann N. Sarkaria, John R. Henley

Published Jun 8, 2013 · Vol. 4, No. 5 · pp. 792-801

Keywords: nanog, glioma, GBM, brain tumor stem cell, multipotency, xenograft, SDF-1

Musashi1 as a potential therapeutic target and diagnostic marker for lung cancer Research Paper

Xiao-Yang Wang, Huina Yu, R. Ilona Linnpoila, Laodong Li, Dangyu Li, Biwen Bo, Hideyuki Okano, Luis O.F. Penalva, Robert I Glazer

Published May 21, 2013 · Vol. 4, No. 5 · pp. 739-750

Keywords: Musashi1, lung cancer, shRNA, beta-catenin, notch, numb

HPV16 E5 and KGFR/FGFR2b interplay in differentiating epithelial cells Research Paper

Valeria Purpura, Francesca Belleudi, Silvia Caputo, Maria Rosaria Torrisi

Published Feb 1, 2013 · Vol. 4, No. 2 · pp. 192-205

Keywords: HPV16 E5, FGFR2b, KGFR, differentiation, human keratinocytes

Targeted Therapy of Advanced Gallbladder Cancer and Cholangiocarcinoma with Aggressive Biology: Eliciting Early Response Signals from Phase 1 trials Research Paper

Ishwaria Subbiah, Vivek Subbiah, Apostolia M Tsimberidou, Aung Naing, Ahmed Kaseb, Javle Milind, Siqing Fu, David S Hong, Sarina Piha-Paul, Jenifer Wheler, Kenneth Hess, Filip Janku, Gerald Falchook, Robert A Wolff, Razelle Kurzrock

Published Jan 27, 2013 · Vol. 4, No. 1 · pp. 153-162

Keywords: Gallbladder Cancer, Cholangiocarcinoma, Phase 1 trials

Altered transcriptome signature of phenotypically normal skin fibroblasts heterozygous for CDKN2A in familial melanoma: relevance to early intervention Research Paper

Meiyun Fan, Susan R. Pfeffer, Henry T. Lynch, Pamela Cassidy, Sancy Leachman, Lawrence M. Pfeffer, Levy Kopelovich

Published Jan 19, 2013 · Vol. 4, No. 1 · pp. 128-141

Keywords: Familial Melanoma, gene expression, CDKN2A, p16, Mutations, Melanoma

Identification of miR-30d as a novel prognostic maker of prostate cancer. Research Paper

Naohito Kobayashi, Hiroji Uemura, Kiyotaka Nagahama, Koji Okudela, Mitsuko Furuya, Yoko Ino, Yusuke Ito, Hisashi Hirano, Yoshiaki Inayama, Ichiro Aoki, Yoji Nagashima, Yoshinobu Kubota, Hitoshi Ishiguro

Published Nov 17, 2012 · Vol. 3, No. 11 · pp. 1455-1471

Keywords: miRNA-30d, prostate cancer, biochemical recurrence, SOCS1

Whole-exome sequencing identifies ATRX mutation as a key molecular determinant in lower-grade glioma Research Paper

Kasthuri Kannan, Akiko Inagaki, Joachim Silber, Daniel Gorovets, Jianan Zhang, Edward R. Kastenhuber, Adriana Heguy, John H. Petrini, Timothy A. Chan, Jason T. Huse

Published Oct 11, 2012 · Vol. 3, No. 10 · pp. 1194-1203

Keywords: glioma, astrocytoma, IDH, ATRX, whole-exome sequencing

Regulation of DNA Damage Following Termination of Hedgehog (HH) Survival Signaling at the level of the GLI Genes in Human Colon Cancer Research Paper

AKWASI AGYEMAN, Tapati Mazumdar, Janet A Houghton

Published Aug 20, 2012 · Vol. 3, No. 8 · pp. 854-868

Keywords: Hedgehog, GLI1/2 inhibition, GANT61, DNA damage, colon cancer

Mitochondrial Fission Induces Glycolytic Reprogramming in Cancer-Associated Myofibroblasts, Driving Stromal Lactate Production, and Early Tumor Growth Research Paper

Carmela Guido, Diana Whitaker-Menezes, Zhao Lin, Richard G. Pestell, Anthony Howell, Teresa A. Zimmers, Mathew C. Casimiro, Saveria Aquila, Sebastiano Ando, Ubaldo E. Martinez-Outschoorn, Federica Sotgia, Michael P. Lisanti

Published Aug 7, 2012 · Vol. 3, No. 8 · pp. 798-810

Methylation profiling of normal individuals reveals mosaic promoter methylation of cancer-associated genes. Research Paper

Lasse S. Kristensen, Michael P. Raynor, Ida L. Candiloro, Alexander Dobrovic

Published May 8, 2012 · Vol. 3, No. 4 · pp. 450-461

Keywords: DNA methylation, epigenetics, biomarkers, high-resolution melting (HRM), methylation-specific PCR (MSP), constitutional methylation

Targeted therapy for hepatocellular carcinoma: novel agents on the horizon Review

Melchiorre Cervello, James A McCubrey, Antonella Cusimano, Nadia Lampiasi, Antonina Azzolina, Giuseppe Montalto

Published Mar 31, 2012 · Vol. 3, No. 3 · pp. 236-260

Keywords: HCC, signaling pathways, EGF/EGFR, Ras/Raf/MEK/ERK, PI3K/PTEN/Akt/mTOR, Wnt/Î²-catenin

MiR-181b: new perspective to evaluate disease progression in chronic lymphocytic leukemia Research Perspective

Carlo Maria Croce, Rosa Visone, Angelo Veronese, Veronica Balatti

Published Feb 18, 2012 · Vol. 3, No. 2 · pp. 195-202

Keywords: miR-181b, diagnosis, CLL

Identification of a chrXq27.3 microRNA cluster associated with early relapse in advanced stage ovarian cancer patients Research Paper

Marina Bagnoli, Loris De Cecco, Anna Granata, Roberta Nicoletti, Edoardo Marchesi, Paola Alberti, Barbara Valeri, Massimo Libra, Mattia Barbareschi, Francesco Raspagliesi, Delia Mezzanzanica, Silvana Canevari

Published Dec 31, 2011 · Vol. 2, No. 12 · pp. 1265-1278

Keywords: advanced-stage ovarian cancer, early relapse, microRNA profiling, miR-506, cisplatin, miR-513a-5p, miR-513b.

Publication Alerts

European Cancer and Oncology Congress

Post-Publication Promotion

Search Oncotarget

Altered glycosylation of MUC1 influences its association with CIN85: the role of this novel complex in cancer cell invasion and migration Research Paper

DHH-RHEBL1 fusion transcript: a novel recurrent feature in the new landscape of pediatric CBFA2T3-GLIS2-positive acute myeloid leukemia Research Paper

Dietary restriction-resistant human tumors harboring the PIK3CA-activating mutation H1047R are sensitive to metformin Research Paper

Increased expression and copy number amplification of LINE-1 and SINE B1 retrotransposable elements in murine mammary carcinoma progression Research Paper

Tumor suppressor genes promote rhabdomyosarcoma progression in p53 heterozygous, HER-2/neu transgenic mice Research Paper

Crucial Role for Early Growth Response-1 in the Transcriptional Regulation of miR-20b in Breast Cancer Research Paper

Targeting mixed lineage kinases in ER-positive breast cancer cells leads to G2/M cell cycle arrest and apoptosis. Research Paper

Brain Tumor Stem Cell Multipotency Correlates with Nanog Expression and Extent of Passaging in Human Glioblastoma Xenografts Research Paper

Musashi1 as a potential therapeutic target and diagnostic marker for lung cancer Research Paper

HPV16 E5 and KGFR/FGFR2b interplay in differentiating epithelial cells Research Paper

Targeted Therapy of Advanced Gallbladder Cancer and Cholangiocarcinoma with Aggressive Biology: Eliciting Early Response Signals from Phase 1 trials Research Paper

Altered transcriptome signature of phenotypically normal skin fibroblasts heterozygous for CDKN2A in familial melanoma: relevance to early intervention Research Paper

Identification of miR-30d as a novel prognostic maker of prostate cancer. Research Paper

Whole-exome sequencing identifies ATRX mutation as a key molecular determinant in lower-grade glioma Research Paper

Regulation of DNA Damage Following Termination of Hedgehog (HH) Survival Signaling at the level of the GLI Genes in Human Colon Cancer Research Paper

Mitochondrial Fission Induces Glycolytic Reprogramming in Cancer-Associated Myofibroblasts, Driving Stromal Lactate Production, and Early Tumor Growth Research Paper

Methylation profiling of normal individuals reveals mosaic promoter methylation of cancer-associated genes. Research Paper

Targeted therapy for hepatocellular carcinoma: novel agents on the horizon Review

MiR-181b: new perspective to evaluate disease progression in chronic lymphocytic leukemia Research Perspective

Identification of a chrXq27.3 microRNA cluster associated with early relapse in advanced stage ovarian cancer patients Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Altered glycosylation of MUC1 influences its association with CIN85: the role of this novel complex in cancer cell invasion and migration Research Paper

DHH-RHEBL1 fusion transcript: a novel recurrent feature in the new landscape of pediatric CBFA2T3-GLIS2-positive acute myeloid leukemia Research Paper

Dietary restriction-resistant human tumors harboring the PIK3CA-activating mutation H1047R are sensitive to metformin Research Paper

Increased expression and copy number amplification of LINE-1 and SINE B1 retrotransposable elements in murine mammary carcinoma progression Research Paper

Tumor suppressor genes promote rhabdomyosarcoma progression in p53 heterozygous, HER-2/neu transgenic mice Research Paper

Crucial Role for Early Growth Response-1 in the Transcriptional Regulation of miR-20b in Breast Cancer Research Paper

Targeting mixed lineage kinases in ER-positive breast cancer cells leads to G2/M cell cycle arrest and apoptosis. Research Paper

Brain Tumor Stem Cell Multipotency Correlates with Nanog Expression and Extent of Passaging in Human Glioblastoma Xenografts Research Paper

Musashi1 as a potential therapeutic target and diagnostic marker for lung cancer Research Paper

HPV16 E5 and KGFR/FGFR2b interplay in differentiating epithelial cells Research Paper

Targeted Therapy of Advanced Gallbladder Cancer and Cholangiocarcinoma with Aggressive Biology: Eliciting Early Response Signals from Phase 1 trials Research Paper

Altered transcriptome signature of phenotypically normal skin fibroblasts heterozygous for CDKN2A in familial melanoma: relevance to early intervention Research Paper

Identification of miR-30d as a novel prognostic maker of prostate cancer. Research Paper

Whole-exome sequencing identifies ATRX mutation as a key molecular determinant in lower-grade glioma Research Paper

Regulation of DNA Damage Following Termination of Hedgehog (HH) Survival Signaling at the level of the GLI Genes in Human Colon Cancer Research Paper

Mitochondrial Fission Induces Glycolytic Reprogramming in Cancer-Associated Myofibroblasts, Driving Stromal Lactate Production, and Early Tumor Growth Research Paper

Methylation profiling of normal individuals reveals mosaic promoter methylation of cancer-associated genes. Research Paper

Targeted therapy for hepatocellular carcinoma: novel agents on the horizon Review

MiR-181b: new perspective to evaluate disease progression in chronic lymphocytic leukemia Research Perspective

Identification of a chrXq27.3 microRNA cluster associated with early relapse in advanced stage ovarian cancer patients Research Paper