The Oncosearch | Oncotarget

DCLK1 is a broadly dysregulated target against epithelial-mesenchymal transition, focal adhesion, and stemness in clear cell renal carcinoma Research Paper

Nathaniel Weygant, Dongfeng Qu, Randal May, Ryan M. Tierney, William L. Berry, Lichao Zhao, Shweta Agarwal, Parthasarathy Chandrakesan, Harisha R. Chinthalapally, Nicholas T. Murphy, James D. Li, Sripathi M. Sureban, Michael J. Schlosser, James J. Tomasek, Courtney W. Houchen

Published Dec 11, 2014 · Vol. 6, No. 4 · pp. 2193-2205

Active secretion of CXCL10 and CCL5 from colorectal cancer microenvironments associates with GranzymeB+ CD8+ T-cell infiltration Research Paper

Timothy J. Zumwalt, Mildred Arnold, Ajay Goel, C. Richard Boland

Published Dec 11, 2014 · Vol. 6, No. 5 · pp. 2981-2991

Hypoxia up-regulates SERPINB3 through HIF-2Î± in human liver cancer cells Research Paper

Stefania Cannito, Cristian Turato, Claudia Paternostro, Alessandra Biasiolo, Sebastiano Colombatto, Irene Cambieri, Santina Quarta, Erica Novo, Elisabetta Morello, Gianmarco Villano, Silvano Fasolato, Tiziana Musso, Ezio David, Ignazia Tusa, Elisabetta Rovida, Riccardo Autelli, Antonina Smedile, Umberto Cillo, Patrizia Pontisso, Maurizio Parola

Published Dec 10, 2014 · Vol. 6, No. 4 · pp. 2206-2221

SKP2 cooperates with N-Ras or AKT to induce liver tumor development in mice Research Paper

Salvatore Delogu, Chunmei Wang, Antonio Cigliano, Kirsten Utpatel, Marcella Sini, Thomas Longerich, Nina Waldburger, Kai Breuhahn, Lijie Jiang, Silvia Ribback, Frank Dombrowski, Matthias Evert, Xin Chen, Diego F. Calvisi

Published Dec 10, 2014 · Vol. 6, No. 4 · pp. 2222-2234

HS-543 induces apoptosis of Imatinib-resistant chronic myelogenous leukemia with T315I mutation Research Paper

Soo Jung Kim, Kyung Hee Jung, Hong Hua Yan, Mi Kwon Son, Zhenghuan Fang, Ye-Lim Ryu, Hyunseung Lee, Joo Han Lim, Jun-Kyu Suh, JinHee Kim, Soyoung Lee, Sungwoo Hong, Soon-Sun Hong

Published Dec 2, 2014 · Vol. 6, No. 3 · pp. 1507-1518

Targeting of hyperactivated mTOR signaling in high-risk acute lymphoblastic leukemia in a pre-clinical model Priority Research Paper

Md. Nabiul Hasan, Manon Queudeville, Luca Trentin, Sarah Mirjam Eckhoff, Ilaria Bronzini, Chiara Palmi, Thomas Barth, Giovanni Cazzaniga, Geertruy te Kronnie, Klaus-Michael Debatin, LÃ¼der Hinrich Meyer

Published Dec 2, 2014 · Vol. 6, No. 3 · pp. 1382-1395

The activity regulation of the mitotic centromere-associated kinesin by Polo-like kinase 1 Research Paper

Andreas Ritter, Mourad Sanhaji, Kerstin SteinhÃ¤user, Susanne Roth, Frank Louwen, Juping Yuan

Published Dec 2, 2014 · Vol. 6, No. 9 · pp. 6641-6655

MUTYH mediates the toxicity of combined DNA 6-thioguanine and UVA radiation Research Paper

Francesca Grasso, Vitalba Ruggieri, Gabriele De Luca, Paola Leopardi, Maria Teresa Mancuso, Ida Casorelli, Pietro Pichierri, Peter Karran, Margherita Bignami

Published Dec 2, 2014 · Vol. 6, No. 10 · pp. 7481-7492

Expansion of CTCs from early stage lung cancer patients using a microfluidic co-culture model Research Paper

Zhuo Zhang, Hiroe Shiratsuchi, Jules Lin, Guoan Chen, Rishindra M. Reddy, Ebrahim Azizi, Shamileh Fouladdel, Andrew C. Chang, Lin Lin, Hui Jiang, Meghna Waghray, Gary Luker, Diane M. Simeone, Max S. Wicha, David G. Beer, Nithya Ramnath, Sunitha Nagrath

Published Dec 1, 2014 · Vol. 5, No. 23 · pp. 12383-12397

Keywords: expansion of CTCs, early stage lung cancer, microfluidic co-culture

Genetic prevention of lymphoma in p53 knockout mice allows the early development of p53-related sarcomas Research Paper

Lorena Landuzzi, Marianna L. Ianzano, Giordano Nicoletti, Arianna Palladini, Valentina Grosso, Dario Ranieri, Massimiliano Dallâ€™Ora, Elena Raschi, Roberta Laranga, Marco Gambarotti, Piero Picci, Carla De Giovanni, Patrizia Nanni, Pier-Luigi Lollini

Published Nov 18, 2014 · Vol. 5, No. 23 · pp. 11924-11938

Gene expression analysis of head and neck squamous cell carcinoma survival and recurrence Clinical Research Papers

Xu Zhi, Katarzyna Lamperska, PaweÅ‚ Golusinski, Nicholas J. Schork, Lukasz Luczewski, Tomasz Kolenda, Wojciech Golusinski, Michal M. Masternak

Published Nov 16, 2014 · Vol. 6, No. 1 · pp. 547-555

Wnt signaling, de novo lipogenesis, adipogenesis and ectopic fat Research Perspective

Kangxing Song, Shuxia Wang, Mitra Mani, Arya Mani

Published Nov 15, 2014 · Vol. 5, No. 22 · pp. 11000-11003

Overcoming resistance to BRAF inhibition in BRAF-mutated metastatic melanoma Review

Francesco Spagnolo, Paola Ghiorzo, Paola Queirolo

Published Nov 15, 2014 · Vol. 5, No. 21 · pp. 10206-10221

Increased fucosylation has a pivotal role in invasive and metastatic properties of head and neck cancer stem cells Research Paper

Vincenzo Desiderio, Petros Papagerakis, Virginia Tirino, Li Zheng, Margarite Matossian, Mark E. Prince, Francesca Paino, Luigi Mele, Federica Papaccio, Roberta Montella, Gianpaolo Papaccio, Silvana Papagerakis

Published Nov 6, 2014 · Vol. 6, No. 1 · pp. 71-84

Human PIF1 helicase supports DNA replication and cell growth under oncogenic-stress Research Paper

Mary E. Gagou, Anil Ganesh, Geraldine Phear, Darren Robinson, Eva Petermann, Angela Cox, Mark Meuth

Published Nov 5, 2014 · Vol. 5, No. 22 · pp. 11381-11398

Keywords: helicases, replication stress, oncogenes, human cells

Molecular profiling of endometrial carcinoma precursor, primary and metastatic lesions suggests different targets for treatment in obese compared to non-obese patients Clinical Research Papers

Anna Berg, Erling A. Hoivik, Siv MjÃ¸s, Frederik Holst, Henrica M. J. Werner, Ingvild L. Tangen, Amaro Taylor-Weiner, William J. Gibson, Kanthida Kusonmano, Elisabeth Wik, Jone Trovik, Mari K. Halle, Anne M. Ã˜yan, Karl-Henning Kalland, Andrew D. Cherniack, Rameen Beroukhim, Ingunn Stefansson, Gordon B. Mills, Camilla Krakstad, Helga B. Salvesen

Published Nov 4, 2014 · Vol. 6, No. 2 · pp. 1327-1339

GALNT2 suppresses malignant phenotypes through IGF-1 receptor and predicts favorable prognosis in neuroblastoma Research Paper

Wan-Ling Ho, Chih-Hsing Chou, Yung-Ming Jeng, Meng-Yao Lu, Yung-Li Yang, Shiann-Tarng Jou, Dong-Tsamn Lin, Hsiu-Hao Chang, Kai-Hsin Lin, Wen-Ming Hsu, Min-Chuan Huang

Published Oct 24, 2014 · Vol. 5, No. 23 · pp. 12247-12259

An angiopoietin-like protein 2 autocrine signaling promotes EMT during pancreatic ductal carcinogenesis Research Paper

Carmine Carbone, Geny Piro, Matteo Fassan, Anna Tamburrino, Maria Mihaela Mina, Marco Zanotto, Paul J. Chiao, Claudio Bassi, Aldo Scarpa, Giampaolo Tortora, Davide Melisi

Published Oct 24, 2014 · Vol. 6, No. 15 · pp. 13822-13834

A phase 1b, open-label study of trebananib plus bevacizumab or motesanib in patients with solid tumours Clinical Research Papers

David S. Hong, Razelle Kurzrock, Marilyn Mulay, Erik Rasmussen, Benjamin M. Wu, Michael B. Bass, Zhandong D. Zhong, Greg Friberg, Lee S. Rosen

Published Oct 23, 2014 · Vol. 5, No. 22 · pp. 11154-11167

Prognostic impact of alternative splicing-derived hMENA isoforms in resected, node-negative, non-small-cell lung cancer Priority Research Paper

Emilio Bria, Francesca Di Modugno, Isabella Sperduti, Pierluigi Iapicca, Paolo Visca, Gabriele Alessandrini, Barbara Antoniani, Sara Pilotto, Vienna Ludovini, Jacopo Vannucci, Guido Bellezza, Angelo Sidoni, Giampaolo Tortora, Derek C. Radisky, Lucio CrinÃ², Francesco Cognetti, Francesco Facciolo, Marcella Mottolese, Michele Milella, Paola NisticÃ²

Published Oct 21, 2014 · Vol. 5, No. 22 · pp. 11054-11063

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DCLK1 is a broadly dysregulated target against epithelial-mesenchymal transition, focal adhesion, and stemness in clear cell renal carcinoma Research Paper

Active secretion of CXCL10 and CCL5 from colorectal cancer microenvironments associates with GranzymeB+ CD8+ T-cell infiltration Research Paper

Hypoxia up-regulates SERPINB3 through HIF-2Î± in human liver cancer cells Research Paper

SKP2 cooperates with N-Ras or AKT to induce liver tumor development in mice Research Paper

HS-543 induces apoptosis of Imatinib-resistant chronic myelogenous leukemia with T315I mutation Research Paper

Targeting of hyperactivated mTOR signaling in high-risk acute lymphoblastic leukemia in a pre-clinical model Priority Research Paper

The activity regulation of the mitotic centromere-associated kinesin by Polo-like kinase 1 Research Paper

MUTYH mediates the toxicity of combined DNA 6-thioguanine and UVA radiation Research Paper

Expansion of CTCs from early stage lung cancer patients using a microfluidic co-culture model Research Paper

Genetic prevention of lymphoma in p53 knockout mice allows the early development of p53-related sarcomas Research Paper

Gene expression analysis of head and neck squamous cell carcinoma survival and recurrence Clinical Research Papers

Wnt signaling, de novo lipogenesis, adipogenesis and ectopic fat Research Perspective

Overcoming resistance to BRAF inhibition in BRAF-mutated metastatic melanoma Review

Increased fucosylation has a pivotal role in invasive and metastatic properties of head and neck cancer stem cells Research Paper

Human PIF1 helicase supports DNA replication and cell growth under oncogenic-stress Research Paper

Molecular profiling of endometrial carcinoma precursor, primary and metastatic lesions suggests different targets for treatment in obese compared to non-obese patients Clinical Research Papers

GALNT2 suppresses malignant phenotypes through IGF-1 receptor and predicts favorable prognosis in neuroblastoma Research Paper

An angiopoietin-like protein 2 autocrine signaling promotes EMT during pancreatic ductal carcinogenesis Research Paper

A phase 1b, open-label study of trebananib plus bevacizumab or motesanib in patients with solid tumours Clinical Research Papers

Prognostic impact of alternative splicing-derived hMENA isoforms in resected, node-negative, non-small-cell lung cancer Priority Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

DCLK1 is a broadly dysregulated target against epithelial-mesenchymal transition, focal adhesion, and stemness in clear cell renal carcinoma Research Paper

Active secretion of CXCL10 and CCL5 from colorectal cancer microenvironments associates with GranzymeB+ CD8+ T-cell infiltration Research Paper

Hypoxia up-regulates SERPINB3 through HIF-2Î± in human liver cancer cells Research Paper

SKP2 cooperates with N-Ras or AKT to induce liver tumor development in mice Research Paper

HS-543 induces apoptosis of Imatinib-resistant chronic myelogenous leukemia with T315I mutation Research Paper

Targeting of hyperactivated mTOR signaling in high-risk acute lymphoblastic leukemia in a pre-clinical model Priority Research Paper

The activity regulation of the mitotic centromere-associated kinesin by Polo-like kinase 1 Research Paper

MUTYH mediates the toxicity of combined DNA 6-thioguanine and UVA radiation Research Paper

Expansion of CTCs from early stage lung cancer patients using a microfluidic co-culture model Research Paper

Genetic prevention of lymphoma in p53 knockout mice allows the early development of p53-related sarcomas Research Paper

Gene expression analysis of head and neck squamous cell carcinoma survival and recurrence Clinical Research Papers

Wnt signaling, de novo lipogenesis, adipogenesis and ectopic fat Research Perspective

Overcoming resistance to BRAF inhibition in BRAF-mutated metastatic melanoma Review

Increased fucosylation has a pivotal role in invasive and metastatic properties of head and neck cancer stem cells Research Paper

Human PIF1 helicase supports DNA replication and cell growth under oncogenic-stress Research Paper

Molecular profiling of endometrial carcinoma precursor, primary and metastatic lesions suggests different targets for treatment in obese compared to non-obese patients Clinical Research Papers

GALNT2 suppresses malignant phenotypes through IGF-1 receptor and predicts favorable prognosis in neuroblastoma Research Paper

An angiopoietin-like protein 2 autocrine signaling promotes EMT during pancreatic ductal carcinogenesis Research Paper

A phase 1b, open-label study of trebananib plus bevacizumab or motesanib in patients with solid tumours Clinical Research Papers

Prognostic impact of alternative splicing-derived hMENA isoforms in resected, node-negative, non-small-cell lung cancer Priority Research Paper