The Oncosearch | Oncotarget

Systematic screening of isogenic cancer cells identifies DUSP6 as context-specific synthetic lethal target in melanoma Research Paper

Stephanie Wittig-Blaich, Rainer Wittig, Steffen Schmidt, Stefan Lyer, Melanie Bewerunge-Hudler, Sabine Gronert-Sum, Olga Strobel-Freidekind, Carolin MÃ¼ller, Markus List, Aleksandra Jaskot, Helle Christiansen, Mathias Hafner, Dirk Schadendorf, Ines Block, Jan Mollenhauer

Published Mar 2, 2017 · Vol. 8, No. 14 · pp. 23760-23774

Fungal lectin MpL enables entry of protein drugs into cancer cells and their subcellular targeting Research Paper

Simon Å½urga, Milica PeriÅ¡iÄ‡ Nanut, Janko Kos, Jerica SabotiÄ

Published Mar 2, 2017 · Vol. 8, No. 16 · pp. 26896-26910

Mitochondrial â€œpowerâ€ drives tamoxifen resistance: NQO1 and GCLC are new therapeutic targets in breast cancer Research Paper

Marco Fiorillo, Federica Sotgia, Diego Sisci, Anna Rita Cappello, Michael P. Lisanti

Published Mar 2, 2017 · Vol. 8, No. 12 · pp. 20309-20327

Pygopus2 inhibits the efficacy of paclitaxel-induced apoptosis and induces multidrug resistance in human glioma cells Research Paper

Cefan Zhou, Hongxia Cheng, Wenying Qin, Yi Zhang, Hui Xiong, Jing Yang, Huang Huang, Yefu Wang, Xing-Zhen Chen, Jingfeng Tang

Published Mar 2, 2017 · Vol. 8, No. 17 · pp. 27915-27928

NCTD promotes Birinapant-mediated anticancer activity in breast cancer cells by downregulation of c-FLIP Research Paper

Li Zhao, Guoshan Yang, Hao Bai, Minghui Zhang, Dongcheng Mou

Published Mar 2, 2017 · Vol. 8, No. 16 · pp. 26886-26895

Acid ceramidase is a novel drug target for pediatric brain tumors Research Paper

Ninh B. Doan, Ha S. Nguyen, Andrew Montoure, Mona M. Al-Gizawiy, Wade M. Mueller, Shekar Kurpad, Scott D. Rand, Jennifer M. Connelly, Christopher R. Chitambar, Kathleen M. Schmainda, Shama P. Mirza

Published Mar 1, 2017 · Vol. 8, No. 15 · pp. 24753-24761

USP22 knockdown enhanced chemosensitivity of hepatocellular carcinoma cells to 5-Fu by up-regulation of Smad4 and suppression of Akt Research Paper

Jing Zhang, Nan Luo, Yu Tian, Jiazhi Li, Xiaozhou Yang, Huimin Yin, Congshu Xiao, Jie Sheng, Yang Li, Bo Tang, Rongkuan Li

Published Mar 1, 2017 · Vol. 8, No. 15 · pp. 24728-24740

Functional characterisation of a novel ovarian cancer cell line, NUOC-1 Research Paper

Aiste McCormick, Eleanor Earp, Katherine Elliot, Gavin Cuthbert, Rachel O'Donnell, Brian T. Wilson, Ruth Sutton, Charlotte Leeson, Huw D. Thomas, Helen Blair, Sarah Fordham, John Lunec, James Allan, Richard J. Edmondson

Published Mar 1, 2017 · Vol. 8, No. 16 · pp. 26832-26844

Î´-Tocotrienol, a natural form of vitamin E, inhibits pancreatic cancer stem-like cells and prevents pancreatic cancer metastasis Research Paper

Kazim Husain, Barbara A. Centeno, Domenico Coppola, Jose Trevino, Said M. Sebti, Mokenge P. Malafa

Published Feb 28, 2017 · Vol. 8, No. 19 · pp. 31554-31567

Molecular docking, 3D-QSAR and structural optimization on imidazo-pyridine derivatives dually targeting AT1 and PPARγ Research Paper

Jun Zhang, Qing-Qing Hao, Xin Liu, Zhi Jing, Wen-Qing Jia, Shu-Qing Wang, Wei-Ren Xu, Xian-Chao Cheng, Run-Ling Wang

Published Feb 28, 2017 · Vol. 8, No. 15 · pp. 25612-25627

Synergistic killing of FLT3ITD-positive AML cells by combined inhibition of tyrosine-kinase activity and N-glycosylation Research Paper

Dimitrios Tsitsipatis, Ashok Kumar Jayavelu, JÃ¶rg P. MÃ¼ller, Reinhard Bauer, Dirk Schmidt-Arras, Siavosh Mahboobi, Tina M. SchnÃ¶der, Florian Heidel, Frank D. BÃ¶hmer

Published Feb 28, 2017 · Vol. 8, No. 16 · pp. 26613-26624

Anti-cancer effect of novel PAK1 inhibitor via induction of PUMA-mediated cell death and p21-mediated cell cycle arrest Research Paper

Tae-Gyun Woo, Min-Ho Yoon, Shin-Deok Hong, Jiyun Choi, Nam-Chul Ha, Hokeun Sun, Bum-Joon Park

Published Feb 28, 2017 · Vol. 8, No. 14 · pp. 23690-23701

Metronomic regimen as an effective treatment for aggressive T-LGL leukemia with central nervous system infiltration: clinical experience and review of literature Review

Yun Liu, Lei Fan, Huihui Zhao, Wei Xu, Jianyong Li

Published Feb 27, 2017 · Vol. 8, No. 19 · pp. 32292-32297

JMJD3 suppresses stem cell-like characteristics in breast cancer cells by downregulation of Oct4 independently of its demethylase activity Research Paper

Jing Xun, Dekun Wang, Long Shen, Junbo Gong, Ruifang Gao, Lingfang Du, Antao Chang, Xiangrong Song, Rong Xiang, Xiaoyue Tan

Published Feb 26, 2017 · Vol. 8, No. 13 · pp. 21918-21929

Overall survival with crizotinib and next-generation ALK inhibitors in ALK-positive non-small-cell lung cancer (IFCT-1302 CLINALK): a French nationwide cohort retrospective study Research Paper

MichaÃ«l Duruisseaux, Benjamin Besse, Jacques Cadranel, Maurice PÃ©rol, Bertrand Mennecier, Laurence Bigay-Game, Renaud Descourt, Eric Dansin, Clarisse Audigier-Valette, Lionel Moreau, JosÃ© Hureaux, Remi Veillon, Josiane Otto, Anne Madroszyk-Flandin, Alexis Cortot, FranÃ§ois Guichard, Pascaline Boudou-Rouquette, Alexandra Langlais, Pascale Missy, Franck Morin, Denis Moro-Sibilot

Published Feb 26, 2017 · Vol. 8, No. 13 · pp. 21903-21917

Fine tuning of vitamin D receptor (VDR) activity by post-transcriptional and post-translational modifications Review

Ondrej Zenata, Radim Vrzal

Published Feb 25, 2017 · Vol. 8, No. 21 · pp. 35390-35402

Immunocompetent mouse allograft models for development of therapies to target breast cancer metastasis Priority Research Paper

Yuan Yang, Howard H. Yang, Ying Hu, Peter H. Watson, Huaitian Liu, Thomas R. Geiger, Miriam R. Anver, Diana C. Haines, Philip Martin, Jeffrey E. Green, Maxwell P. Lee, Kent W. Hunter, Lalage M. Wakefield

Published Feb 25, 2017 · Vol. 8, No. 19 · pp. 30621-30643

Repressing CD147 is a novel therapeutic strategy for malignant melanoma Review

Xing Hu, Juan Su, Youyou Zhou, Xiaoyun Xie, Cong Peng, Zhimin Yuan, Xiang Chen

Published Feb 25, 2017 · Vol. 8, No. 15 · pp. 25806-25813

Quantification of HER2 and estrogen receptor heterogeneity in breast cancer by single-molecule RNA fluorescence in situ hybridization Research Paper

Laura Annaratone, Michele Simonetti, Erik Wernersson, Caterina MarchiÃ², Silvano Garnerone, Maria Stella Scalzo, Magda Bienko, Roberto Chiarle, Anna Sapino, Nicola Crosetto

Published Feb 25, 2017 · Vol. 8, No. 12 · pp. 18680-18698

Azilsartan ameliorates apoptosis of dopaminergicÂ neurons and rescues characteristic parkinsonian behaviors in a rat model of Parkinsonâ€™s disease Research Paper

Qing Gao, Zhou Ou, Teng Jiang, You-Yong Tian, Jun-Shan Zhou, Liang Wu, Jian-Quan Shi, Ying-Dong Zhang

Published Feb 25, 2017 · Vol. 8, No. 15 · pp. 24099-24109

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Systematic screening of isogenic cancer cells identifies DUSP6 as context-specific synthetic lethal target in melanoma Research Paper

Fungal lectin MpL enables entry of protein drugs into cancer cells and their subcellular targeting Research Paper

Mitochondrial â€œpowerâ€ drives tamoxifen resistance: NQO1 and GCLC are new therapeutic targets in breast cancer Research Paper

Pygopus2 inhibits the efficacy of paclitaxel-induced apoptosis and induces multidrug resistance in human glioma cells Research Paper

NCTD promotes Birinapant-mediated anticancer activity in breast cancer cells by downregulation of c-FLIP Research Paper

Acid ceramidase is a novel drug target for pediatric brain tumors Research Paper

USP22 knockdown enhanced chemosensitivity of hepatocellular carcinoma cells to 5-Fu by up-regulation of Smad4 and suppression of Akt Research Paper

Functional characterisation of a novel ovarian cancer cell line, NUOC-1 Research Paper

Î´-Tocotrienol, a natural form of vitamin E, inhibits pancreatic cancer stem-like cells and prevents pancreatic cancer metastasis Research Paper

Molecular docking, 3D-QSAR and structural optimization on imidazo-pyridine derivatives dually targeting AT1 and PPARγ Research Paper

Synergistic killing of FLT3ITD-positive AML cells by combined inhibition of tyrosine-kinase activity and N-glycosylation Research Paper

Anti-cancer effect of novel PAK1 inhibitor via induction of PUMA-mediated cell death and p21-mediated cell cycle arrest Research Paper

Metronomic regimen as an effective treatment for aggressive T-LGL leukemia with central nervous system infiltration: clinical experience and review of literature Review

JMJD3 suppresses stem cell-like characteristics in breast cancer cells by downregulation of Oct4 independently of its demethylase activity Research Paper

Overall survival with crizotinib and next-generation ALK inhibitors in ALK-positive non-small-cell lung cancer (IFCT-1302 CLINALK): a French nationwide cohort retrospective study Research Paper

Fine tuning of vitamin D receptor (VDR) activity by post-transcriptional and post-translational modifications Review

Immunocompetent mouse allograft models for development of therapies to target breast cancer metastasis Priority Research Paper

Repressing CD147 is a novel therapeutic strategy for malignant melanoma Review

Quantification of HER2 and estrogen receptor heterogeneity in breast cancer by single-molecule RNA fluorescence in situ hybridization Research Paper

Azilsartan ameliorates apoptosis of dopaminergicÂ neurons and rescues characteristic parkinsonian behaviors in a rat model of Parkinsonâ€™s disease Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Systematic screening of isogenic cancer cells identifies DUSP6 as context-specific synthetic lethal target in melanoma Research Paper

Fungal lectin MpL enables entry of protein drugs into cancer cells and their subcellular targeting Research Paper

Mitochondrial â€œpowerâ€ drives tamoxifen resistance: NQO1 and GCLC are new therapeutic targets in breast cancer Research Paper

Pygopus2 inhibits the efficacy of paclitaxel-induced apoptosis and induces multidrug resistance in human glioma cells Research Paper

NCTD promotes Birinapant-mediated anticancer activity in breast cancer cells by downregulation of c-FLIP Research Paper

Acid ceramidase is a novel drug target for pediatric brain tumors Research Paper

USP22 knockdown enhanced chemosensitivity of hepatocellular carcinoma cells to 5-Fu by up-regulation of Smad4 and suppression of Akt Research Paper

Functional characterisation of a novel ovarian cancer cell line, NUOC-1 Research Paper

Î´-Tocotrienol, a natural form of vitamin E, inhibits pancreatic cancer stem-like cells and prevents pancreatic cancer metastasis Research Paper

Molecular docking, 3D-QSAR and structural optimization on imidazo-pyridine derivatives dually targeting AT1 and PPARγ Research Paper

Synergistic killing of FLT3ITD-positive AML cells by combined inhibition of tyrosine-kinase activity and N-glycosylation Research Paper

Anti-cancer effect of novel PAK1 inhibitor via induction of PUMA-mediated cell death and p21-mediated cell cycle arrest Research Paper

Metronomic regimen as an effective treatment for aggressive T-LGL leukemia with central nervous system infiltration: clinical experience and review of literature Review

JMJD3 suppresses stem cell-like characteristics in breast cancer cells by downregulation of Oct4 independently of its demethylase activity Research Paper

Overall survival with crizotinib and next-generation ALK inhibitors in ALK-positive non-small-cell lung cancer (IFCT-1302 CLINALK): a French nationwide cohort retrospective study Research Paper

Fine tuning of vitamin D receptor (VDR) activity by post-transcriptional and post-translational modifications Review

Immunocompetent mouse allograft models for development of therapies to target breast cancer metastasis Priority Research Paper

Repressing CD147 is a novel therapeutic strategy for malignant melanoma Review

Quantification of HER2 and estrogen receptor heterogeneity in breast cancer by single-molecule RNA fluorescence in situ hybridization Research Paper

Azilsartan ameliorates apoptosis of dopaminergicÂ neurons and rescues characteristic parkinsonian behaviors in a rat model of Parkinsonâ€™s disease Research Paper

Mitochondrial â€œpowerâ€ drives tamoxifen resistance: NQO1 and GCLC are new therapeutic targets in breast cancer Research Paper