The Oncosearch | Oncotarget

Hematopoietic cell kinase (HCK) as a therapeutic target in immune and cancer cells Review

Ashleigh R. Poh, Robert J.J. Oâ€™Donoghue, Matthias Ernst

Published Jun 10, 2015 · Vol. 6, No. 18 · pp. 15752-15771

The MDM2-inhibitor Nutlin-3 synergizes with cisplatin to induce p53 dependent tumor cell apoptosis in non-small cell lung cancer Research Paper

Christophe Deben, An Wouters, Ken Op de Beeck, Jolien van Den Bossche, Julie Jacobs, Karen Zwaenepoel, Marc Peeters, Jan Van Meerbeeck, Filip Lardon, Christian Rolfo, Vanessa Deschoolmeester, Patrick Pauwels

Published Jun 10, 2015 · Vol. 6, No. 26 · pp. 22666-22679

Mitochondrial biogenesis is required for the anchorage-independent survival and propagation of stem-like cancer cells Priority Research Paper

Arianna De Luca, Marco Fiorillo, Maria Peiris-PagÃ¨s, Bela Ozsvari, Duncan L. Smith, Rosa Sanchez-Alvarez, Ubaldo E. Martinez-Outschoorn, Anna Rita Cappello, Vincenzo Pezzi, Michael P. Lisanti, Federica Sotgia

Published Jun 9, 2015 · Vol. 6, No. 17 · pp. 14777-14795

Targeting chemotherapy-induced PTX3 in tumor stroma to prevent the progression of drug-resistant cancers Research Paper

Jhih-Ying Chi, Yu-Wei Hsiao, Chien-Feng Li, Yu-Chih Lo, Zu-Yau Lin, Jhen-Yi Hong, Yang-Ming Liu, Xiu Han, Shao-Ming Wang, Ben-Kuen Chen, Kelvin K. Tsai, Ju-Ming Wang

Published Jun 8, 2015 · Vol. 6, No. 27 · pp. 23987-24001

Regulation of sensitivity of tumor cells to antitubulin drugs by Cdk1-TAZ signalling Research Paper

Yulei Zhao, Xiaolong Yang

Published Jun 8, 2015 · Vol. 6, No. 26 · pp. 21906-21917

Activation of microRNA-494-targeting Bmi1 and ADAM10 by silibinin ablates cancer stemness and predicts favourable prognostic value in head and neck squamous cell carcinomas Research Paper

Yu-Chao Chang, Chia-Ing Jan, Chih-Yu Peng, Yu-Chi Lai, Fang-Wei Hu, Cheng-Chia Yu

Published Jun 8, 2015 · Vol. 6, No. 27 · pp. 24002-24016

Doxorubicin induces apoptosis by targeting Madcam1 and AKT and inhibiting protein translation initiation in hepatocellular carcinoma cells Research Paper

Jiayi Wang, Lifang Ma, Xun Tang, Xiao Zhang, Yongxia Qiao, Yuling Shi, Yanfeng Xu, Zhongyong Wang, Yongchun Yu, Fenyong Sun

Published Jun 8, 2015 · Vol. 6, No. 27 · pp. 24075-24091

Combining BET and HDAC inhibitors synergistically induces apoptosis of melanoma and suppresses AKT and YAP signaling Research Paper

Anja Heinemann, Carleen Cullinane, Ricardo De Paoli-Iseppi, James S. Wilmott, Dilini Gunatilake, Jason Madore, Dario Strbenac, Jean Y. Yang, Kavitha Gowrishankar, Jessamy C. Tiffen, Rab K. Prinjha, Nicholas Smithers, Grant A. McArthur, Peter Hersey, Stuart J. Gallagher

Published Jun 5, 2015 · Vol. 6, No. 25 · pp. 21507-21521

Metformin inhibits cell cycle progression of B-cell chronic lymphocytic leukemia cells Research Paper

Silvia Bruno, Bernardetta Ledda, Claudya Tenca, Silvia Ravera, Anna Maria Orengo, Andrea Nicola Mazzarello, Elisa Pesenti, Salvatore Casciaro, Omar Racchi, Fabio Ghiotto, Cecilia Marini, Gianmario Sambuceti, Andrea DeCensi, Franco Fais

Published Jun 5, 2015 · Vol. 6, No. 26 · pp. 22624-22640

GPER agonist G-1 decreases adrenocortical carcinoma (ACC) cell growth in vitro and in vivo Research Paper

Adele Chimento, Rosa Sirianni, Ivan Casaburi, Fabiana Zolea, Pietro Rizza, Paola Avena, Rocco Malivindi, Arianna De Luca, Carmela Campana, Emilia Martire, Francesco Domanico, Francesco Fallo, Giulia Carpinelli, Lidia Cerquetti, Donatella Amendola, Antonio Stigliano, Vincenzo Pezzi

Published Jun 5, 2015 · Vol. 6, No. 22 · pp. 19190-19203

Nrf2 activity as a potential biomarker for the pan-epigenetic anticancer agent, RRx-001 Research Paper

Shoucheng Ning, Thillai Veerapazham Sekar, Jan Scicinski, Bryan Oronsky, Donna M. Peehl, Susan J. Knox, Ramasamy Paulmurugan

Published Jun 4, 2015 · Vol. 6, No. 25 · pp. 21547-21556

p53 attenuates AKT signaling by modulating membrane phospholipid composition Research Paper

Natalia Rueda-Rincon, Katarzyna Bloch, Rita Derua, Rajesh Vyas, Amy Harms, Thomas Hankemeier, Niamat Ali Khan, Jonas Dehairs, Muralidhararao Bagadi, Maria Mercedes Binda, Etienne Waelkens, Jean-Christophe Marine, Johannes V. Swinnen

Published Jun 3, 2015 · Vol. 6, No. 25 · pp. 21240-21254

Natural paniceins from mediterranean sponge inhibit the multidrug resistance activity of patched and increase chemotherapy efficiency on melanoma cells Research Paper

Laura Fiorini, Marie-Aude Tribalat, Lucy Sauvard, Julie Cazareth, Enzo Lalli, Isabelle Broutin, Olivier P. Thomas, Isabelle Mus-Veteau

Published Jun 1, 2015 · Vol. 6, No. 26 · pp. 22282-22297

Discovery of new small molecules inhibiting 67 kDa laminin receptor interaction with laminin and cancer cell invasion Research Paper

Ada Pesapane, Carmen Di Giovanni, Francesca Wanda Rossi, Daniela Alfano, Luigi Formisano, Pia Ragno, Carmine Selleri, Nunzia Montuori, Antonio Lavecchia

Published May 29, 2015 · Vol. 6, No. 20 · pp. 18116-18133

The potential utility of acetyltanshinone IIA in the treatment of HER2-overexpressed breast cancer: Induction of cancer cell death by targeting apoptotic and metabolic signaling pathways Research Paper

Mounia Guerram, Zhen-Zhou Jiang, Bashir Alsiddig Yousef, Aida Mejda Hamdi, Hozeifa Mohamed Hassan, Zi-Qiao Yuan, Hou-Wei Luo, Xiong Zhu, Lu-Yong Zhang

Published May 28, 2015 · Vol. 6, No. 26 · pp. 21865-21877

Identification of alsterpaullone as a novel small molecule inhibitor to target group 3 medulloblastoma Research Paper

Claudia C. Faria, Sameer Agnihotri, Stephen C. Mack, Brian J. Golbourn, Roberto J. Diaz, Samantha Olsen, Melissa Bryant, Matthew Bebenek, Xin Wang, Kelsey C. Bertrand, Michelle Kushida, Renee Head, Ian Clark, Peter Dirks, Christian A. Smith, Michael D. Taylor, James T. Rutka

Published May 28, 2015 · Vol. 6, No. 25 · pp. 21718-21729

The neuroleptic drug pimozide inhibits stem-like cell maintenance and tumorigenicity in hepatocellular carcinoma Research Paper

Jia-Jie Chen, Nan Cai, Guan-Zhong Chen, Chang-Chang Jia, Dong-Bo Qiu, Cong Du, Wei Liu, Yang Yang, Zi-Jie Long, Qi Zhang

Published May 27, 2015 · Vol. 8, No. 11 · pp. 17593-17609

Underexpression of LKB1 tumor suppressor is associated with enhanced Wnt signaling and malignant characteristics of human intrahepatic cholangiocarcinoma Research Paper

Jinghan Wang, Keqiang Zhang, Jinhui Wang, Xiwei Wu, Xiyong Liu, Bin Li, Yan Zhu, Yong Yu, Qingbao Cheng, Zhenli Hu, Chao Guo, Shuya Hu, Bing Mu, Chun-Hao Tsai, Jie Li, Lynne Smith, Lu Yang, Qi Liu, Peiguo Chu, Vincent Chang, Baihe Zhang, Mengchao Wu, Xiaoqing Jiang, Yun Yen

Published May 27, 2015 · Vol. 6, No. 22 · pp. 18905-18920

Patient-derived bladder cancer xenografts in the preclinical development of novel targeted therapies Research Paper

Wolfgang JÃ¤ger, Hui Xue, Tetsutaro Hayashi, Claudia Janssen, Shannon Awrey, Alexander W. Wyatt, Shawn Anderson, Igor Moskalev, Anne Haegert, Mohammed Alshalalfa, Nicholas Erho, Elai Davicioni, Ladan Fazli, Estelle Li, Colin Collins, Yuzhuo Wang, Peter C. Black

Published May 27, 2015 · Vol. 6, No. 25 · pp. 21522-21532

Anticancer activity of MPT0G157, a derivative of indolylbenzenesulfonamide, inhibits tumor growth and angiogenesis Research Paper

Yen-Chia Huang, Fang-I Huang, Samir Mehndiratta, Ssu-Chia Lai, Jing-Ping Liou, Chia-Ron Yang

Published May 27, 2015 · Vol. 6, No. 21 · pp. 18590-18601

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Hematopoietic cell kinase (HCK) as a therapeutic target in immune and cancer cells Review

The MDM2-inhibitor Nutlin-3 synergizes with cisplatin to induce p53 dependent tumor cell apoptosis in non-small cell lung cancer Research Paper

Mitochondrial biogenesis is required for the anchorage-independent survival and propagation of stem-like cancer cells Priority Research Paper

Targeting chemotherapy-induced PTX3 in tumor stroma to prevent the progression of drug-resistant cancers Research Paper

Regulation of sensitivity of tumor cells to antitubulin drugs by Cdk1-TAZ signalling Research Paper

Activation of microRNA-494-targeting Bmi1 and ADAM10 by silibinin ablates cancer stemness and predicts favourable prognostic value in head and neck squamous cell carcinomas Research Paper

Doxorubicin induces apoptosis by targeting Madcam1 and AKT and inhibiting protein translation initiation in hepatocellular carcinoma cells Research Paper

Combining BET and HDAC inhibitors synergistically induces apoptosis of melanoma and suppresses AKT and YAP signaling Research Paper

Metformin inhibits cell cycle progression of B-cell chronic lymphocytic leukemia cells Research Paper

GPER agonist G-1 decreases adrenocortical carcinoma (ACC) cell growth in vitro and in vivo Research Paper

Nrf2 activity as a potential biomarker for the pan-epigenetic anticancer agent, RRx-001 Research Paper

p53 attenuates AKT signaling by modulating membrane phospholipid composition Research Paper

Natural paniceins from mediterranean sponge inhibit the multidrug resistance activity of patched and increase chemotherapy efficiency on melanoma cells Research Paper

Discovery of new small molecules inhibiting 67 kDa laminin receptor interaction with laminin and cancer cell invasion Research Paper

The potential utility of acetyltanshinone IIA in the treatment of HER2-overexpressed breast cancer: Induction of cancer cell death by targeting apoptotic and metabolic signaling pathways Research Paper

Identification of alsterpaullone as a novel small molecule inhibitor to target group 3 medulloblastoma Research Paper

The neuroleptic drug pimozide inhibits stem-like cell maintenance and tumorigenicity in hepatocellular carcinoma Research Paper

Underexpression of LKB1 tumor suppressor is associated with enhanced Wnt signaling and malignant characteristics of human intrahepatic cholangiocarcinoma Research Paper

Patient-derived bladder cancer xenografts in the preclinical development of novel targeted therapies Research Paper

Anticancer activity of MPT0G157, a derivative of indolylbenzenesulfonamide, inhibits tumor growth and angiogenesis Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Hematopoietic cell kinase (HCK) as a therapeutic target in immune and cancer cells Review

The MDM2-inhibitor Nutlin-3 synergizes with cisplatin to induce p53 dependent tumor cell apoptosis in non-small cell lung cancer Research Paper

Mitochondrial biogenesis is required for the anchorage-independent survival and propagation of stem-like cancer cells Priority Research Paper

Targeting chemotherapy-induced PTX3 in tumor stroma to prevent the progression of drug-resistant cancers Research Paper

Regulation of sensitivity of tumor cells to antitubulin drugs by Cdk1-TAZ signalling Research Paper

Activation of microRNA-494-targeting Bmi1 and ADAM10 by silibinin ablates cancer stemness and predicts favourable prognostic value in head and neck squamous cell carcinomas Research Paper

Doxorubicin induces apoptosis by targeting Madcam1 and AKT and inhibiting protein translation initiation in hepatocellular carcinoma cells Research Paper

Combining BET and HDAC inhibitors synergistically induces apoptosis of melanoma and suppresses AKT and YAP signaling Research Paper

Metformin inhibits cell cycle progression of B-cell chronic lymphocytic leukemia cells Research Paper

GPER agonist G-1 decreases adrenocortical carcinoma (ACC) cell growth in vitro and in vivo Research Paper

Nrf2 activity as a potential biomarker for the pan-epigenetic anticancer agent, RRx-001 Research Paper

p53 attenuates AKT signaling by modulating membrane phospholipid composition Research Paper

Natural paniceins from mediterranean sponge inhibit the multidrug resistance activity of patched and increase chemotherapy efficiency on melanoma cells Research Paper

Discovery of new small molecules inhibiting 67 kDa laminin receptor interaction with laminin and cancer cell invasion Research Paper

The potential utility of acetyltanshinone IIA in the treatment of HER2-overexpressed breast cancer: Induction of cancer cell death by targeting apoptotic and metabolic signaling pathways Research Paper

Identification of alsterpaullone as a novel small molecule inhibitor to target group 3 medulloblastoma Research Paper

The neuroleptic drug pimozide inhibits stem-like cell maintenance and tumorigenicity in hepatocellular carcinoma Research Paper

Underexpression of LKB1 tumor suppressor is associated with enhanced Wnt signaling and malignant characteristics of human intrahepatic cholangiocarcinoma Research Paper

Patient-derived bladder cancer xenografts in the preclinical development of novel targeted therapies Research Paper

Anticancer activity of MPT0G157, a derivative of indolylbenzenesulfonamide, inhibits tumor growth and angiogenesis Research Paper