The Oncosearch | Oncotarget

Pretreatment with VEGF(R)-inhibitors reduces interstitial fluid pressure, increases intraperitoneal chemotherapy drug penetration, and impedes tumor growth in a mouse colorectal carcinomatosis model Research Paper

FÃ©lix Gremonprez, Benedicte Descamps, Andrei Izmer, Christian Vanhove, Frank Vanhaecke, Olivier De Wever, Wim Ceelen

Published Sep 7, 2015 · Vol. 6, No. 30 · pp. 29889-29900

Repositioning antipsychotic chlorpromazine for treating colorectal cancer by inhibiting sirtuin 1 Research Paper

Wen-Ying Lee, Wai-Theng Lee, Chia-Hsiung Cheng, Ku-Chung Chen, Chih-Ming Chou, Chu-Hung Chung, Min-Siou Sun, Hung-Wei Cheng, Meng-Ni Ho, Cheng-Wei Lin

Published Sep 5, 2015 · Vol. 6, No. 29 · pp. 27580-27595

Apigenin blocks IKKÎ± activation and suppresses prostate cancer progression Research Paper

Sanjeev Shukla, Rajnee Kanwal, Eswar Shankar, Manish Datt, Mark R. Chance, Pingfu Fu, Gregory T. MacLennan, Sanjay Gupta

Published Sep 5, 2015 · Vol. 6, No. 31 · pp. 31216-31232

Ibrutinib selectively and irreversibly targets EGFR (L858R, Del19) mutant but is moderately resistant to EGFR (T790M) mutant NSCLC Cells Research Paper

Hong Wu, Aoli Wang, Wei Zhang, Beilei Wang, Cheng Chen, Wenchao Wang, Chen Hu, Zi Ye, Zheng Zhao, Li Wang, Xixiang Li, Kailin Yu, Juan Liu, Jiaxin Wu, Xiao-E Yan, Peng Zhao, Jinhua Wang, Chu Wang, Ellen L. Weisberg, Nathanael S. Gray, Cai-Hong Yun, Jing Liu, Liang Chen, Qingsong Liu

Published Sep 5, 2015 · Vol. 6, No. 31 · pp. 31313-31322

B5, a thioredoxin reductase inhibitor, induces apoptosis in human cervical cancer cells by suppressing the thioredoxin system, disrupting mitochondrion-dependent pathways and triggering autophagy Research Paper

Fang-Yuan Shao, Zhi-Yun Du, Dong-Lei Ma, Wen-Bo Chen, Wu-Yu Fu, Bi-Bo Ruan, Wen Rui, Jia-Xuan Zhang, Sheng Wang, Nai Sum Wong, Hao Xiao, Man-Mei Li, Xiao Liu, Qiu-Ying Liu, Xiao-dong Zhou, Hai-Zhao Yan, Yi-Fei Wang, Chang-Yan Chen, Zhong Liu, Hong-Yuan Chen

Published Sep 4, 2015 · Vol. 6, No. 31 · pp. 30939-30956

Targeted therapy for Epstein-Barr virus-associated gastric carcinoma using low-dose gemcitabine-induced lytic activation Research Paper

Hyun Gyu Lee, Hyemi Kim, Eun Jung Kim, Pil-Gu Park, Seung Myung Dong, Tae Hyun Choi, Hyunki Kim, Curtis R. Chong, Jun O. Liu, Jianmeng Chen, Richard F. Ambinder, S. Diane Hayward, Jeon Han Park, Jae Myun Lee

Published Sep 4, 2015 · Vol. 6, No. 31 · pp. 31018-31029

Acquisition of a single EZH2 D1 domain mutation confers acquired resistance to EZH2-targeted inhibitors Research Paper

Theresa Baker, Sujata Nerle, Justin Pritchard, Boyang Zhao, Victor M. Rivera, Andrew Garner, Francois Gonzalvez

Published Sep 2, 2015 · Vol. 6, No. 32 · pp. 32646-32655

Base excision repair-mediated resistance to cisplatin in KRAS(G12C) mutant NSCLC cells Research Paper

Elisa Caiola, Daniela Salles, Roberta Frapolli, Monica Lupi, Giuseppe Rotella, Anna Ronchi, Marina Chiara Garassino, Nikola Mattschas, Stefano Colavecchio, Massimo Broggini, Lisa WiesmÃ¼ller, Mirko Marabese

Published Sep 2, 2015 · Vol. 6, No. 30 · pp. 30072-30087

Rapid targeted somatic mutation analysis of solid tumors in routine clinical diagnostics Research Paper

Gilda Magliacane, Greta Grassini, Paola Bartocci, Ilaria Francaviglia, Elena Dal Cin, Gianluca Barbieri, Gianluigi Arrigoni, Lorenza Pecciarini, Claudio Doglioni, Maria Giulia Cangi

Published Sep 2, 2015 · Vol. 6, No. 31 · pp. 30592-30603

Stathmin 1 inhibition amplifies ruxolitinib-induced apoptosis in JAK2^V617F cells Research Paper

JoÃ£o Agostinho Machado-Neto, Paula de Melo Campos, Patricia Favaro, Mariana Lazarini, Adriana da Silva Santos Duarte, Irene Lorand-Metze, Fernando Ferreira Costa, Sara Teresinha Olalla Saad, Fabiola Traina

Published Aug 24, 2015 · Vol. 6, No. 30 · pp. 29573-29584

RPS3 regulates melanoma cell growth and apoptosis by targeting Cyto C/Ca²⁺/MICU1 dependent mitochondrial signaling Research Paper

Yun Tian, Lijun Qin, Huijuan Qiu, Dingbo Shi, Rui Sun, Wenbing Li, Tianze Liu, Jingshu Wang, Tingting Xu, Wei Guo, Tiebang Kang, Wenlin Huang, Guowen Wang, Wuguo Deng

Published Aug 22, 2015 · Vol. 6, No. 30 · pp. 29614-29625

A novel immune resistance mechanism of melanoma cells controlled by the ADAR1 enzyme Research Paper

Gilli Galore-Haskel, Yael Nemlich, Eyal Greenberg, Shira Ashkenazi, Motti Hakim, Orit Itzhaki, Noa Shoshani, Ronnie Shapira-Fromer, Eytan Ben-Ami, Efrat Ofek, Liat Anafi, Michal J. Besser, Jacob Schachter, Gal Markel

Published Aug 21, 2015 · Vol. 6, No. 30 · pp. 28999-29015

Inhibition of DNA-repair genes Ercc1 and Mgmt enhances temozolomide efficacy in gliomas treatment: a pre-clinical study Research Paper

Sandra G. Boccard, Sandie V. Marand, Sandra Geraci, Laurie Pycroft, FranÃ§ois R. Berger, Laurent A. Pelletier

Published Aug 20, 2015 · Vol. 6, No. 30 · pp. 29456-29468

Inhibition of autophagy potentiates pemetrexed and simvastatin-induced apoptotic cell death in malignant mesothelioma and non-small cell lung cancer cells Research Paper

Ki-Eun Hwang, Young-Suk Kim, Jae-Wan Jung, Su-Jin Kwon, Do-Sim Park, Byong-Ki Cha, Seon-Hee Oh, Kwon-Ha Yoon, Eun-Taik Jeong, Hak-Ryul Kim

Published Aug 20, 2015 · Vol. 6, No. 30 · pp. 29482-29496

Membrane associated cancer-oocyte neoantigen SAS1B/ovastacin is a candidate immunotherapeutic target for uterine tumors Research Paper

Eusebio S Pires, Ryan S Dâ€™Souza, Marisa A Needham, Austin K Herr, Amir A Jazaeri, Hui Li, Mark H Stoler, Kiley L Anderson-Knapp, Theodore Thomas, Arabinda Mandal, Alain Gougeon, Charles J Flickinger, David E Bruns, Brian A Pollok, John C Herr

Published Aug 18, 2015 · Vol. 6, No. 30 · pp. 30194-30211

Digital PCR analysis of plasma cell-free DNA for non-invasive detection of drug resistance mechanisms in EGFR mutant NSCLC: Correlation with paired tumor samples Research Paper

Hidenobu Ishii, Koichi Azuma, Kazuko Sakai, Akihiko Kawahara, Kazuhiko Yamada, Takaaki Tokito, Isamu Okamoto, Kazuto Nishio, Tomoaki Hoshino

Published Aug 17, 2015 · Vol. 6, No. 31 · pp. 30850-30858

Transcriptome analysis indicates TFEB1 and YEATS4 as regulatory transcription factors for drug resistance of ovarian cancer Research Paper

Yi Rang Kim, Mi Sung Park, Ki Hwan Eum, Juhee Kim, Jeong Won Lee, Taejeong Bae, Dae Ho Lee, Jin Woo Choi

Published Aug 17, 2015 · Vol. 6, No. 31 · pp. 31030-31038

Azathioprine induction of tumors with microsatellite instability: risk evaluation using a mouse model Research Paper

Sahra Bodo, Magali Svrcek, Isabelle Sourrouille, Peggy CuilliÃ¨res-Dartigues, Tatiana Ledent, Sylvie Dumont, Laetitia Dinard, Philippe Lafitte, Camille Capel, Ada Collura, Olivier Buhard, Kristell Wanherdrick, Alexandra Chalastanis, Virginie Penard-Lacronique, Bettina Fabiani, Jean-FranÃ§ois FlÃ©jou, Nicole Brousse, Laurent Beaugerie, Alex Duval, Martine Muleris

Published Aug 17, 2015 · Vol. 6, No. 28 · pp. 24969-24977

Inhibition of glucose-6-phosphate dehydrogenase sensitizes cisplatin-resistant cells to death Research Paper

Daniela Catanzaro, Edoardo Gaude, Genny Orso, Carla Giordano, Giulia Guzzo, Andrea Rasola, Eugenio Ragazzi, Laura Caparrotta, Christian Frezza, Monica Montopoli

Published Aug 17, 2015 · Vol. 6, No. 30 · pp. 30102-30114

Prognostic clinical factors in pretreated colorectal cancer patients receiving regorafenib: implications for clinical management. Clinical Research Papers

Michela Del Prete, Riccardo Giampieri, Fotios Loupakis, Tiziana Prochilo, Lisa Salvatore, Luca Faloppi, Maristella Bianconi, Alessandro Bittoni, Giuseppe Aprile, Alberto Zaniboni, Alfredo Falcone, Mario Scartozzi, Stefano Cascinu

Published Aug 17, 2015 · Vol. 6, No. 32 · pp. 33982-33992

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Pretreatment with VEGF(R)-inhibitors reduces interstitial fluid pressure, increases intraperitoneal chemotherapy drug penetration, and impedes tumor growth in a mouse colorectal carcinomatosis model Research Paper

Repositioning antipsychotic chlorpromazine for treating colorectal cancer by inhibiting sirtuin 1 Research Paper

Apigenin blocks IKKÎ± activation and suppresses prostate cancer progression Research Paper

Ibrutinib selectively and irreversibly targets EGFR (L858R, Del19) mutant but is moderately resistant to EGFR (T790M) mutant NSCLC Cells Research Paper

B5, a thioredoxin reductase inhibitor, induces apoptosis in human cervical cancer cells by suppressing the thioredoxin system, disrupting mitochondrion-dependent pathways and triggering autophagy Research Paper

Targeted therapy for Epstein-Barr virus-associated gastric carcinoma using low-dose gemcitabine-induced lytic activation Research Paper

Acquisition of a single EZH2 D1 domain mutation confers acquired resistance to EZH2-targeted inhibitors Research Paper

Base excision repair-mediated resistance to cisplatin in KRAS(G12C) mutant NSCLC cells Research Paper

Rapid targeted somatic mutation analysis of solid tumors in routine clinical diagnostics Research Paper

Stathmin 1 inhibition amplifies ruxolitinib-induced apoptosis in JAK2^V617F cells Research Paper

RPS3 regulates melanoma cell growth and apoptosis by targeting Cyto C/Ca²⁺/MICU1 dependent mitochondrial signaling Research Paper

A novel immune resistance mechanism of melanoma cells controlled by the ADAR1 enzyme Research Paper

Inhibition of DNA-repair genes Ercc1 and Mgmt enhances temozolomide efficacy in gliomas treatment: a pre-clinical study Research Paper

Inhibition of autophagy potentiates pemetrexed and simvastatin-induced apoptotic cell death in malignant mesothelioma and non-small cell lung cancer cells Research Paper

Membrane associated cancer-oocyte neoantigen SAS1B/ovastacin is a candidate immunotherapeutic target for uterine tumors Research Paper

Digital PCR analysis of plasma cell-free DNA for non-invasive detection of drug resistance mechanisms in EGFR mutant NSCLC: Correlation with paired tumor samples Research Paper

Transcriptome analysis indicates TFEB1 and YEATS4 as regulatory transcription factors for drug resistance of ovarian cancer Research Paper

Azathioprine induction of tumors with microsatellite instability: risk evaluation using a mouse model Research Paper

Inhibition of glucose-6-phosphate dehydrogenase sensitizes cisplatin-resistant cells to death Research Paper

Prognostic clinical factors in pretreated colorectal cancer patients receiving regorafenib: implications for clinical management. Clinical Research Papers

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Pretreatment with VEGF(R)-inhibitors reduces interstitial fluid pressure, increases intraperitoneal chemotherapy drug penetration, and impedes tumor growth in a mouse colorectal carcinomatosis model Research Paper

Repositioning antipsychotic chlorpromazine for treating colorectal cancer by inhibiting sirtuin 1 Research Paper

Apigenin blocks IKKÎ± activation and suppresses prostate cancer progression Research Paper

Ibrutinib selectively and irreversibly targets EGFR (L858R, Del19) mutant but is moderately resistant to EGFR (T790M) mutant NSCLC Cells Research Paper

B5, a thioredoxin reductase inhibitor, induces apoptosis in human cervical cancer cells by suppressing the thioredoxin system, disrupting mitochondrion-dependent pathways and triggering autophagy Research Paper

Targeted therapy for Epstein-Barr virus-associated gastric carcinoma using low-dose gemcitabine-induced lytic activation Research Paper

Acquisition of a single EZH2 D1 domain mutation confers acquired resistance to EZH2-targeted inhibitors Research Paper

Base excision repair-mediated resistance to cisplatin in KRAS(G12C) mutant NSCLC cells Research Paper

Rapid targeted somatic mutation analysis of solid tumors in routine clinical diagnostics Research Paper

Stathmin 1 inhibition amplifies ruxolitinib-induced apoptosis in JAK2V617F cells Research Paper

RPS3 regulates melanoma cell growth and apoptosis by targeting Cyto C/Ca2+/MICU1 dependent mitochondrial signaling Research Paper

A novel immune resistance mechanism of melanoma cells controlled by the ADAR1 enzyme Research Paper

Inhibition of DNA-repair genes Ercc1 and Mgmt enhances temozolomide efficacy in gliomas treatment: a pre-clinical study Research Paper

Inhibition of autophagy potentiates pemetrexed and simvastatin-induced apoptotic cell death in malignant mesothelioma and non-small cell lung cancer cells Research Paper

Membrane associated cancer-oocyte neoantigen SAS1B/ovastacin is a candidate immunotherapeutic target for uterine tumors Research Paper

Digital PCR analysis of plasma cell-free DNA for non-invasive detection of drug resistance mechanisms in EGFR mutant NSCLC: Correlation with paired tumor samples Research Paper

Transcriptome analysis indicates TFEB1 and YEATS4 as regulatory transcription factors for drug resistance of ovarian cancer Research Paper

Azathioprine induction of tumors with microsatellite instability: risk evaluation using a mouse model Research Paper

Inhibition of glucose-6-phosphate dehydrogenase sensitizes cisplatin-resistant cells to death Research Paper

Prognostic clinical factors in pretreated colorectal cancer patients receiving regorafenib: implications for clinical management. Clinical Research Papers

Stathmin 1 inhibition amplifies ruxolitinib-induced apoptosis in JAK2^V617F cells Research Paper

RPS3 regulates melanoma cell growth and apoptosis by targeting Cyto C/Ca²⁺/MICU1 dependent mitochondrial signaling Research Paper