The Oncosearch | Oncotarget

Complementary dynamic BH3 profiles predict co-operativity between the multi-kinase inhibitor TG02 and the BH3 mimetic ABT-199 in acute myeloid leukaemia cells Research Paper

Monica Pallis, Francis Burrows, Jeremy Ryan, Martin Grundy, Claire Seedhouse, Amina Abdul-Aziz, Joan Montero, Anthony Letai, Nigel Russell

Published Apr 15, 2016 · Vol. 8, No. 10 · pp. 16220-16232

Structural basis for small molecule targeting of the programmed death ligand 1 (PD-L1) Research Paper

Krzysztof M. Zak, Przemyslaw Grudnik, Katarzyna Guzik, Bartosz J. Zieba, Bogdan Musielak, Alexander DÃ¶mling, Grzegorz Dubin, Tad A. Holak

Published Apr 13, 2016 · Vol. 7, No. 21 · pp. 30323-30335

Predicting cancer-relevant proteins using an improved molecular similarity ensemble approach Research Paper

Bin Zhou, Qi Sun, De-Xin Kong

Published Apr 13, 2016 · Vol. 7, No. 22 · pp. 32394-32407

Nuclear factor one B (NFIB) encodes a subtype-specific tumour suppressor in glioblastoma Research Paper

Brett W. Stringer, Jens Bunt, Bryan W. Day, Guy Barry, Paul R. Jamieson, Kathleen S. Ensbey, Zara C. Bruce, Kate GoasdouÃ©, HÃ©lÃ¨ne Vidal, Sara Charmsaz, Fiona M. Smith, Leanne T. Cooper, Michael Piper, Andrew W. Boyd, Linda J. Richards

Published Apr 13, 2016 · Vol. 7, No. 20 · pp. 29306-29320

Reduction of microRNA-184 by E6 oncoprotein confers cisplatin resistance in lung cancer via increasing Bcl-2 Research Paper

Min-Che Tung, Po-Lin Lin, Ya-Wen Cheng, De-Wei Wu, Sauh-Der Yeh, Chi-Yi Chen, Huei Lee

Published Apr 12, 2016 · Vol. 7, No. 22 · pp. 32362-32374

Changes in cytochrome P450s-mediated drug clearance in patients with hepatocellular carcinoma in vitro and in vivo: a bottom-up approach Research Paper

Jie Gao, Jun Zhou, Xiao-Pei He, Yun-Fei Zhang, Na Gao, Xin Tian, Yan Fang, Qiang Wen, Lin-Jing Jia, Han Jin, Hai-Ling Qiao

Published Apr 12, 2016 · Vol. 7, No. 19 · pp. 28612-28623

Lapatinib-loaded human serum albumin nanoparticles for the prevention and treatment of triple-negative breast cancer metastasis to the brain Research Paper

Xu Wan, Xiaoyao Zheng, Xiaoyin Pang, Zhiqing Pang, Jingjing Zhao, Zheming Zhang, Tao Jiang, Wei Xu, Qizhi Zhang, Xinguo Jiang

Published Apr 12, 2016 · Vol. 7, No. 23 · pp. 34038-34051

Use of a MCL-1 inhibitor alone to de-bulk melanoma and in combination to kill melanoma initiating cells Research Paper

Nabanita Mukherjee, Yan Lu, Adam Almeida, Karoline Lambert, Chung-Wai Shiau, Jung-Chen Su, Yuchun Luo, Mayumi Fujita, William A. Robinson, Steven E. Robinson, David A. Norris, Yiqun G. Shellman

Published Apr 12, 2016 · Vol. 8, No. 29 · pp. 46801-46817

Novel CD7-specific nanobody-based immunotoxins potently enhanced apoptosis of CD7-positive malignant cells Research Paper

Jinle Tang, Jialu Li, Xuejun Zhu, Yuan Yu, Dan Chen, Lei Yuan, Zhenyang Gu, Xingding Zhang, Lin Qi, Zhishu Gong, Pengjun Jiang, Juhua Yu, Huimin Meng, Gangli An, Huyong Zheng, Lin Yang

Published Apr 12, 2016 · Vol. 7, No. 23 · pp. 34070-34083

Relationship between hypoxia and response to antiangiogenic therapy in metastatic colorectal cancer Review

Paola Ulivi, Giorgia Marisi, Alessandro Passardi

Published Apr 12, 2016 · Vol. 7, No. 29 · pp. 46678-46691

Characterization of selective and potent PI3KÎ´ inhibitor (PI3KDIN- 015) for B-Cell malignances Research Paper

Xiaochuan Liu, Aoli Wang, Xiaofei Liang, Cheng Chen, Juanjuan Liu, Zheng Zhao, Hong Wu, Yuanxin Deng, Li Wang, Beilei Wang, Jiaxin Wu, Feiyang Liu, Stacey M. Fernandes, Sophia Adamia, Richard M. Stone, Ilene A. Galinsky, Jennifer R. Brown, James D. Griffin, Shanchun Zhang, Teckpeng Loh, Xin Zhang, Wenchao Wang, Ellen L. Weisberg, Jing Liu, Qingsong Liu

Published Apr 12, 2016 · Vol. 7, No. 22 · pp. 32641-32651

Dual inhibition of AKT/FLT3-ITD by A674563 overcomes FLT3 ligand-induced drug resistance in FLT3-ITD positive AML Research Paper

Aoli Wang, Hong Wu, Cheng Chen, Chen Hu, Ziping Qi, Wenchao Wang, Kailin Yu, Xiaochuan Liu, Fengming Zou, Zheng Zhao, Jiaxin Wu, Juan Liu, Feiyang Liu, Li Wang, Richard M. Stone, Ilene A. Galinksy, James D. Griffin, Shanchun Zhang, Ellen L. Weisberg, Jing Liu, Qingsong Liu

Published Apr 11, 2016 · Vol. 7, No. 20 · pp. 29131-29142

Hepatocyte SLAMF3 reduced specifically the multidrugs resistance protein MRP-1 and increases HCC cells sensitization to anti-cancer drugs Research Paper

GrÃ©gory Fouquet, VÃ©ronique Debuysscher, Hakim Ouled-Haddou, MÃ©lanie Simoes Eugenio, Baptiste Demey, Amrathlal Rabbind Singh, ChristÃ¨le Ossart, Mohammed Al Bagami, Jean-Marc Regimbeau, Eric Nguyen-Khac, Mickael Naassila, Ingrid Marcq, Hicham Bouhlal

Published Apr 11, 2016 · Vol. 7, No. 22 · pp. 32493-32503

Phase I clinical study of RG7356, an anti-CD44 humanized antibody, in patients with acute myeloid leukemia Research Paper

Norbert Vey, Jacques Delaunay, Giovanni Martinelli, Walter Fiedler, Emmanuel Raffoux, Thomas Prebet, Carlos Gomez-Roca, Cristina Papayannidis, Maxim Kebenko, Peter Paschka, Randolph Christen, Ernesto Guarin, Ann-Marie BrÃ¶ske, Monika Baehner, Michael Brewster, Antje-Christine Walz, Francesca Michielin, Valeria Runza, Valerie Meresse, Christian Recher

Published Apr 11, 2016 · Vol. 7, No. 22 · pp. 32532-32542

Acquired resistance to combination treatment through loss of synergy with MEK and PI3K inhibitors in colorectal cancer Research Paper

Bhaskar Bhattacharya, Sarah Hong Hui Low, Mei Ling Chong, Dilys Chia, King Xin Koh, Nur Sabrina Sapari, Stanley Kaye, Huynh Hung, Touati Benoukraf, Richie Soong

Published Apr 11, 2016 · Vol. 7, No. 20 · pp. 29187-29198

Sulfasalazine impacts on ferroptotic cell death and alleviates the tumor microenvironment and glioma-induced brain edema Research Paper

Tina Sehm, Zheng Fan, Ali Ghoochani, Manfred Rauh, Tobias Engelhorn, Georgia Minakaki, Arnd DÃ¶rfler, Jochen Klucken, Michael Buchfelder, Ilker Y. EyÃ¼poglu, Nicolai Savaskan

Published Apr 8, 2016 · Vol. 7, No. 24 · pp. 36021-36033

The novel tankyrase inhibitor (AZ1366) enhances irinotecan activity in tumors that exhibit elevated tankyrase and irinotecan resistance Research Paper

Kevin S. Quackenbush, Stacey Bagby, Wai Meng Tai, Wells A. Messersmith, Anna Schreiber, Justin Greene, Jihye Kim, Guoliang Wang, Alicia Purkey, Todd M. Pitts, Anna Nguyen, Dexiang Gao, Patrick Blatchford, Anna Capasso, Alwin G. Schuller, S. Gail Eckhardt, John J. Arcaroli

Published Apr 7, 2016 · Vol. 7, No. 19 · pp. 28273-28285

Repurposed drug screen identifies cardiac glycosides as inhibitors of TGF-Î²-induced cancer-associated fibroblast differentiation Research Paper

David T. Coleman, Alana L. Gray, Charles A. Stephens, Matthew L. Scott, James A. Cardelli

Published Apr 6, 2016 · Vol. 7, No. 22 · pp. 32200-32209

Quercetin and doxorubicin co-encapsulated biotin receptor-targeting nanoparticles for minimizing drug resistance in breast cancer Research Paper

Li Lv, Chunxia Liu, Chuxiong Chen, Xiaoxia Yu, Guanghui Chen, Yonghui Shi, Fengchao Qin, Jiebin Ou, Kaifeng Qiu, Guocheng Li

Published Apr 6, 2016 · Vol. 7, No. 22 · pp. 32184-32199

Pattern of RECK CpG methylation as a potential marker for predicting breast cancer prognosis and drug-sensitivity Research Paper

Gongping Shi, Yoko Yoshida, Kanako Yuki, Tomomi Nishimura, Yukiko Kawata, Masahiro Kawashima, Keiko Iwaisako, Kiyotsugu Yoshikawa, Junichi Kurebayashi, Masakazu Toi, Makoto Noda

Published Apr 6, 2016 · Vol. 7, No. 50 · pp. 82158-82169

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Complementary dynamic BH3 profiles predict co-operativity between the multi-kinase inhibitor TG02 and the BH3 mimetic ABT-199 in acute myeloid leukaemia cells Research Paper

Structural basis for small molecule targeting of the programmed death ligand 1 (PD-L1) Research Paper

Predicting cancer-relevant proteins using an improved molecular similarity ensemble approach Research Paper

Nuclear factor one B (NFIB) encodes a subtype-specific tumour suppressor in glioblastoma Research Paper

Reduction of microRNA-184 by E6 oncoprotein confers cisplatin resistance in lung cancer via increasing Bcl-2 Research Paper

Changes in cytochrome P450s-mediated drug clearance in patients with hepatocellular carcinoma in vitro and in vivo: a bottom-up approach Research Paper

Lapatinib-loaded human serum albumin nanoparticles for the prevention and treatment of triple-negative breast cancer metastasis to the brain Research Paper

Use of a MCL-1 inhibitor alone to de-bulk melanoma and in combination to kill melanoma initiating cells Research Paper

Novel CD7-specific nanobody-based immunotoxins potently enhanced apoptosis of CD7-positive malignant cells Research Paper

Relationship between hypoxia and response to antiangiogenic therapy in metastatic colorectal cancer Review

Characterization of selective and potent PI3KÎ´ inhibitor (PI3KDIN- 015) for B-Cell malignances Research Paper

Dual inhibition of AKT/FLT3-ITD by A674563 overcomes FLT3 ligand-induced drug resistance in FLT3-ITD positive AML Research Paper

Hepatocyte SLAMF3 reduced specifically the multidrugs resistance protein MRP-1 and increases HCC cells sensitization to anti-cancer drugs Research Paper

Phase I clinical study of RG7356, an anti-CD44 humanized antibody, in patients with acute myeloid leukemia Research Paper

Acquired resistance to combination treatment through loss of synergy with MEK and PI3K inhibitors in colorectal cancer Research Paper

Sulfasalazine impacts on ferroptotic cell death and alleviates the tumor microenvironment and glioma-induced brain edema Research Paper

The novel tankyrase inhibitor (AZ1366) enhances irinotecan activity in tumors that exhibit elevated tankyrase and irinotecan resistance Research Paper

Repurposed drug screen identifies cardiac glycosides as inhibitors of TGF-Î²-induced cancer-associated fibroblast differentiation Research Paper

Quercetin and doxorubicin co-encapsulated biotin receptor-targeting nanoparticles for minimizing drug resistance in breast cancer Research Paper

Pattern of RECK CpG methylation as a potential marker for predicting breast cancer prognosis and drug-sensitivity Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Complementary dynamic BH3 profiles predict co-operativity between the multi-kinase inhibitor TG02 and the BH3 mimetic ABT-199 in acute myeloid leukaemia cells Research Paper

Structural basis for small molecule targeting of the programmed death ligand 1 (PD-L1) Research Paper

Predicting cancer-relevant proteins using an improved molecular similarity ensemble approach Research Paper

Nuclear factor one B (NFIB) encodes a subtype-specific tumour suppressor in glioblastoma Research Paper

Reduction of microRNA-184 by E6 oncoprotein confers cisplatin resistance in lung cancer via increasing Bcl-2 Research Paper

Changes in cytochrome P450s-mediated drug clearance in patients with hepatocellular carcinoma in vitro and in vivo: a bottom-up approach Research Paper

Lapatinib-loaded human serum albumin nanoparticles for the prevention and treatment of triple-negative breast cancer metastasis to the brain Research Paper

Use of a MCL-1 inhibitor alone to de-bulk melanoma and in combination to kill melanoma initiating cells Research Paper

Novel CD7-specific nanobody-based immunotoxins potently enhanced apoptosis of CD7-positive malignant cells Research Paper

Relationship between hypoxia and response to antiangiogenic therapy in metastatic colorectal cancer Review

Characterization of selective and potent PI3KÎ´ inhibitor (PI3KDIN- 015) for B-Cell malignances Research Paper

Dual inhibition of AKT/FLT3-ITD by A674563 overcomes FLT3 ligand-induced drug resistance in FLT3-ITD positive AML Research Paper

Hepatocyte SLAMF3 reduced specifically the multidrugs resistance protein MRP-1 and increases HCC cells sensitization to anti-cancer drugs Research Paper

Phase I clinical study of RG7356, an anti-CD44 humanized antibody, in patients with acute myeloid leukemia Research Paper

Acquired resistance to combination treatment through loss of synergy with MEK and PI3K inhibitors in colorectal cancer Research Paper

Sulfasalazine impacts on ferroptotic cell death and alleviates the tumor microenvironment and glioma-induced brain edema Research Paper

The novel tankyrase inhibitor (AZ1366) enhances irinotecan activity in tumors that exhibit elevated tankyrase and irinotecan resistance Research Paper

Repurposed drug screen identifies cardiac glycosides as inhibitors of TGF-Î²-induced cancer-associated fibroblast differentiation Research Paper

Quercetin and doxorubicin co-encapsulated biotin receptor-targeting nanoparticles for minimizing drug resistance in breast cancer Research Paper

Pattern of RECK CpG methylation as a potential marker for predicting breast cancer prognosis and drug-sensitivity Research Paper