The Oncosearch | Oncotarget

Pathogenic mutations and overall survival in 3,084 patients with cancer: the Hellenic Cooperative Oncology Group Precision Medicine Initiative Research Paper

Elena Fountzilas, Vassiliki Kotoula, Georgia-Angeliki Koliou, Eleni Giannoulatou, Helen Gogas, Christos Papadimitriou, Ioannis Tikas, Jianhua Zhang, Kyriaki Papadopoulou, Flora Zagouri, Christos Christodoulou, Angelos Koutras, Thomas Makatsoris, Sofia Chrisafi, Helena Linardou, Ioannis Varthalitis, George Papatsibas, Evangelia Razis, Pavlos Papakostas, Epaminontas Samantas, Gerasimos Aravantinos, Dimitrios Bafaloukos, Paris Kosmidis, Anna Koumarianou, Amanda Psyrri, Georgios Pentheroudakis, Dimitrios Pectasides, Andrew Futreal, George Fountzilas, Apostolia M. Tsimberidou

Published Jan 7, 2020 · Vol. 11, No. 1 · pp. 1-14

Keywords: actionable gene, next-generation sequencing, pathogenic mutation, precision oncology, prognosis

Flow cytometric significance of cellular alkaline phosphatase activity in acute myeloid leukemia Research Paper

Laura G. Rico, Jordi Juncà, Michael D. Ward, Jolene A. Bradford, Jordi Petriz

Published Dec 10, 2019 · Vol. 10, No. 65 · pp. 6969-6980

Keywords: alkaline phosphatase, acute myeloid leukemia, stem cells, leukemic stem cells, CD34

The phytohormone forchlorfenuron decreases viability and proliferation of malignant mesothelioma cells in vitro and in vivo Research Paper

Walter Blum, Thomas Henzi, László Pecze, Kim-Long Diep, Christian G. Bochet, Beat Schwaller

Published Dec 10, 2019 · Vol. 10, No. 65 · pp. 6944-6956

Keywords: malignant mesothelioma, septin cytoskeleton, septin 7, forchlorfenuron, FCF

An innovative diagnostic strategy for the detection of rare molecular targets to select cancer patients for tumor-agnostic treatments Research Paper

Antonio Marchetti, Alessia Di Lorito, Lara Felicioni, Fiamma Buttitta

Published Dec 10, 2019 · Vol. 10, No. 65 · pp. 6957-6968

Keywords: tumor-agnostic treatments, microsatellite instability (MSI), neurotrophic receptor tyrosine kinase (NRTK), tissue microarrays (TMAs), tissue slice arrays (TSAs)

Tumor tissue hnRNP M and HSP 90α as potential predictors of disease-specific mortality in patients with early-stage cutaneous head and neck melanoma: A proteomics-based study Research Paper

Andro Košec, Ruđer Novak, Paško Konjevoda, Vladimir Trkulja, Vladimir Bedeković, Lovorka Grgurević

Published Nov 19, 2019 · Vol. 10, No. 62 · pp. 6713-6722

Keywords: melanoma, early stage, proteomics, tissue, biomarkers

Molecular profiling of radical prostatectomy tissue from patients with no sign of progression identifies ERG as the strongest independent predictor of recurrence Research Paper

Wusheng Yan, Muhammad Jamal, Shyh-Han Tan, Yingjie Song, Denise Young, Yongmei Chen, Shilpa Katta, Kai Ying, Lakshmi Ravindranath, Tarah Woodle, Indu Kohaar, Jennifer Cullen, Jacob Kagan, Sudhir Srivastava, Albert Dobi, David G. McLeod, Inger L. Rosner, Isabell A. Sesterhenn, Alagarsamy Srinivasan, Shiv Srivastava, Gyorgy Petrovics

Published Nov 5, 2019 · Vol. 10, No. 60 · pp. 6466-6483

Keywords: prostate cancer, NanoString, prognostic biomarker, biochemical recurrence, ERG

Characterizing CD44 regulatory microRNAs as putative therapeutic agents in human melanoma Research Paper

Johannes Fänder, Heike Kielstein, Maximilian Büttner, Peter Koelblinger, Reinhard Dummer, Marcus Bauer, Diana Handke, Claudia Wickenhauser, Barbara Seliger, Simon Jasinski-Bergner

Published Nov 5, 2019 · Vol. 10, No. 60 · pp. 6509-6525

Keywords: CD44, CD44v6, melanoma, microRNA, immune cell infiltration

Esophageal 3D organoids of MPV17^-/- mouse model of mitochondrial DNA depletion show epithelial cell plasticity and telomere attrition Research Paper

Manti Guha, Satish Srinivasan, Maura M. Sheehan, Takashi Kijima, Gordon Ruthel, Kelly Whelan, Koji Tanaka, Andres Klein-Szanto, Prasanna M. Chandramouleeswaran, Hiroshi Nakagawa, Narayan G. Avadhani

Published Oct 22, 2019 · Vol. 10, No. 58 · pp. 6245-6259

Keywords: mitochondrial DNA, MPV17, ESCC, telomere, 3D organoid

Multiplatform profiling of pancreatic neuroendocrine tumors: Correlative analyses of clinicopathologic factors and identification of co-occurring pathogenic alterations Research Paper

Jun Gong, Edik M. Blais, Joseph R. Bender, Michelle Guan, Veronica Placencio-Hickok, Emanuel F. Petricoin, Michael J. Pishvaian, Gary Gregory, Richard Tuli, Andrew E. Hendifar

Published Oct 22, 2019 · Vol. 10, No. 58 · pp. 6260-6268

Keywords: pancreatic neuroendocrine tumors, genomic profiling, proteomic profiling, molecular pathways, co-occurring alterations

Malignant ascites: a source of therapeutic protein against ovarian cancer? Research Paper

Pascale Ribaux, Aurore Britan, Gabriele Thumann, Florence Delie, Patrick Petignat, Marie Cohen

Published Oct 15, 2019 · Vol. 10, No. 57 · pp. 5894-5905

Keywords: ascites, PEDF, sleeping beauty transposon, ovarian cancer, tumor development

Fewer actionable mutations but higher tumor mutational burden characterizes NSCLC in black patients at an urban academic medical center Research Paper

Noura J. Choudhury, Mansooreh Eghtesad, Sabah Kadri, John Cursio, Lauren Ritterhouse, Jeremy Segal, Aliya Husain, Jyoti D. Patel

Published Oct 8, 2019 · Vol. 10, No. 56 · pp. 5817-5823

Keywords: non-small cell lung cancer, healthcare disparities, targeted therapies, immunotherapies, biomarkers

The role of CD24 in multiple myeloma tumorigenicity and effects of the microenvironment on its expression Research Paper

Nechama Gilad, Hila Zukerman, Marjorie Pick, Moshe E. Gatt

Published Sep 10, 2019 · Vol. 10, No. 52 · pp. 5480-5491

Keywords: multiple myeloma, CD24, microenvironment, cell cycle and apoptosis changes, tumorigenicity

Prognostic value of tumor growth kinetic parameters in prostate cancer patients Research Paper

Gennady M. Zharinov, Oleg A. Bogomolov, Natalia Yu. Neklasova, Grigory A. Raskin, Irina V. Chepurnaya, Sergey N. Bugrov, Vladimir N. Anisimov

Published Aug 20, 2019 · Vol. 10, No. 49 · pp. 5020-5027

Keywords: prostate cancer, cellular lost factor, Ki-67, prostate specific antigen doubling time, prognostic factors

ALK mutation dynamics and clonal evolution in a neuroblastoma model exhibiting two ALK mutations Research Paper

Simon Durand, Cécile Pierre-Eugène, Olivier Mirabeau, Caroline Louis-Brennetot, Valérie Combaret, Léo Colmet-Daage, Orphée Blanchard, Angela Bellini, Estelle Daudigeos-Dubus, Virginie Raynal, Gudrun Schleiermacher, Sylvain Baulande, Olivier Delattre, Isabelle Janoueix-Lerosey

Published Aug 13, 2019 · Vol. 10, No. 48 · pp. 4937-4950

Keywords: neuroblastoma, ALK mutations, heterogeneity, clonal evolution, ALK inhibitors

Methylation alteration of SHANK1 as a predictive, diagnostic and prognostic biomarker for chronic lymphocytic leukemia Research Paper

Eleonora Loi, Loredana Moi, Antonio Fadda, Giannina Satta, Mariagrazia Zucca, Sonia Sanna, Shadi Amini Nia, Giuseppina Cabras, Marina Padoan, Corrado Magnani, Lucia Miligi, Sara Piro, Davide Gentilini, Maria Grazia Ennas, Melissa C. Southey, Graham G. Giles, Nicole Wong Doo, Pierluigi Cocco, Patrizia Zavattari

Published Aug 13, 2019 · Vol. 10, No. 48 · pp. 4987-5002

Keywords: cancer methylation alteration, predictive biomarkers, diagnostic biomarkers, prognostic biomarkers, SHANK1

Cartilage oligomeric matrix protein in patients with osteoarthritis is independently associated with metastatic disease in prostate cancer Research Paper

Samuel Rosas, Ryan T. Hughes, Michael Farris, Hwajin Lee, Emory R. McTyre, Johannes F. Plate, Lihong Shi, Cynthia L. Emory, A. William Blackstock, Bethany A. Kerr, Jeffrey S. Willey

Published Jul 30, 2019 · Vol. 10, No. 46 · pp. 4776-4785

Keywords: prostate cancer, osteoarthritis, distant metastasis, arthroplasty, joint surgery

Impact on survival of tobacco smoking for cases with oropharyngeal squamous cell carcinoma and known human papillomavirus and p16-status: a multicenter retrospective study Research Paper

Christian Grønhøj, Jakob Schmidt Jensen, Steffen Wagner, Christian Dehlendorff, Jeppe Friborg, Elo Andersen, Claus Wittekindt, Nora Würdemann, Shachi Jenny Sharma, Stefan Gattenlöhner, Jens Peter Klussmann, Christian von Buchwald

Published Jul 23, 2019 · Vol. 10, No. 45 · pp. 4655-4663

Keywords: oropharyngeal cancer, human papillomavirus, smoking, survival

CpG promoter hypo-methylation and up-regulation of microRNA-190b in hormone receptor-positive breast cancer Research Paper

Elisabet Frick, Thorkell Gudjonsson, Jorunn Eyfjord, Jon Jonasson, Laufey Tryggvadóttir, Olafur Stefansson, Stefan Sigurdsson

Published Jul 23, 2019 · Vol. 10, No. 45 · pp. 4664-4678

Keywords: breast cancer, microRNA-190b, DNA methylation, prognosis, estrogen receptor

Cell-free DNA in newly diagnosed patients with glioblastoma – a clinical prospective feasibility study Research Paper

Dorte Schou Nørøxe, Olga Østrup, Christina Westmose Yde, Lise Barlebo Ahlborn, Finn Cilius Nielsen, Signe Regner Michaelsen, Vibeke Andrée Larsen, Jane Skjøth-Rasmussen, Jannick Brennum, Petra Hamerlik, Hans Skovgaard Poulsen, Ulrik Lassen

Published Jul 9, 2019 · Vol. 10, No. 43 · pp. 4397-4406

Keywords: glioblastoma, liquid biopsy, cell-free DNA, fragment length, base-pair

CD90^low MSCs modulate intratumoral immunity to confer antitumor activity in a mouse model of ovarian cancer Research Paper

Yang Zeng, Binghao Li, Tao Li, Wei Liu, Chongzhao Ran, Richard T. Penson, Mark C. Poznansky, Yanan Du, Huabiao Chen

Published Jul 9, 2019 · Vol. 10, No. 43 · pp. 4479-4491

Keywords: mesenchymal stem cells, CD90, ovarian cancer, immunotherapy

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Pathogenic mutations and overall survival in 3,084 patients with cancer: the Hellenic Cooperative Oncology Group Precision Medicine Initiative Research Paper

Flow cytometric significance of cellular alkaline phosphatase activity in acute myeloid leukemia Research Paper

The phytohormone forchlorfenuron decreases viability and proliferation of malignant mesothelioma cells in vitro and in vivo Research Paper

An innovative diagnostic strategy for the detection of rare molecular targets to select cancer patients for tumor-agnostic treatments Research Paper

Tumor tissue hnRNP M and HSP 90α as potential predictors of disease-specific mortality in patients with early-stage cutaneous head and neck melanoma: A proteomics-based study Research Paper

Molecular profiling of radical prostatectomy tissue from patients with no sign of progression identifies ERG as the strongest independent predictor of recurrence Research Paper

Characterizing CD44 regulatory microRNAs as putative therapeutic agents in human melanoma Research Paper

Esophageal 3D organoids of MPV17^-/- mouse model of mitochondrial DNA depletion show epithelial cell plasticity and telomere attrition Research Paper

Multiplatform profiling of pancreatic neuroendocrine tumors: Correlative analyses of clinicopathologic factors and identification of co-occurring pathogenic alterations Research Paper

Malignant ascites: a source of therapeutic protein against ovarian cancer? Research Paper

Fewer actionable mutations but higher tumor mutational burden characterizes NSCLC in black patients at an urban academic medical center Research Paper

The role of CD24 in multiple myeloma tumorigenicity and effects of the microenvironment on its expression Research Paper

Prognostic value of tumor growth kinetic parameters in prostate cancer patients Research Paper

ALK mutation dynamics and clonal evolution in a neuroblastoma model exhibiting two ALK mutations Research Paper

Methylation alteration of SHANK1 as a predictive, diagnostic and prognostic biomarker for chronic lymphocytic leukemia Research Paper

Cartilage oligomeric matrix protein in patients with osteoarthritis is independently associated with metastatic disease in prostate cancer Research Paper

Impact on survival of tobacco smoking for cases with oropharyngeal squamous cell carcinoma and known human papillomavirus and p16-status: a multicenter retrospective study Research Paper

CpG promoter hypo-methylation and up-regulation of microRNA-190b in hormone receptor-positive breast cancer Research Paper

Cell-free DNA in newly diagnosed patients with glioblastoma – a clinical prospective feasibility study Research Paper

CD90^low MSCs modulate intratumoral immunity to confer antitumor activity in a mouse model of ovarian cancer Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Pathogenic mutations and overall survival in 3,084 patients with cancer: the Hellenic Cooperative Oncology Group Precision Medicine Initiative Research Paper

Flow cytometric significance of cellular alkaline phosphatase activity in acute myeloid leukemia Research Paper

The phytohormone forchlorfenuron decreases viability and proliferation of malignant mesothelioma cells in vitro and in vivo Research Paper

An innovative diagnostic strategy for the detection of rare molecular targets to select cancer patients for tumor-agnostic treatments Research Paper

Tumor tissue hnRNP M and HSP 90α as potential predictors of disease-specific mortality in patients with early-stage cutaneous head and neck melanoma: A proteomics-based study Research Paper

Molecular profiling of radical prostatectomy tissue from patients with no sign of progression identifies ERG as the strongest independent predictor of recurrence Research Paper

Characterizing CD44 regulatory microRNAs as putative therapeutic agents in human melanoma Research Paper

Esophageal 3D organoids of MPV17-/- mouse model of mitochondrial DNA depletion show epithelial cell plasticity and telomere attrition Research Paper

Multiplatform profiling of pancreatic neuroendocrine tumors: Correlative analyses of clinicopathologic factors and identification of co-occurring pathogenic alterations Research Paper

Malignant ascites: a source of therapeutic protein against ovarian cancer? Research Paper

Fewer actionable mutations but higher tumor mutational burden characterizes NSCLC in black patients at an urban academic medical center Research Paper

The role of CD24 in multiple myeloma tumorigenicity and effects of the microenvironment on its expression Research Paper

Prognostic value of tumor growth kinetic parameters in prostate cancer patients Research Paper

ALK mutation dynamics and clonal evolution in a neuroblastoma model exhibiting two ALK mutations Research Paper

Methylation alteration of SHANK1 as a predictive, diagnostic and prognostic biomarker for chronic lymphocytic leukemia Research Paper

Cartilage oligomeric matrix protein in patients with osteoarthritis is independently associated with metastatic disease in prostate cancer Research Paper

Impact on survival of tobacco smoking for cases with oropharyngeal squamous cell carcinoma and known human papillomavirus and p16-status: a multicenter retrospective study Research Paper

CpG promoter hypo-methylation and up-regulation of microRNA-190b in hormone receptor-positive breast cancer Research Paper

Cell-free DNA in newly diagnosed patients with glioblastoma – a clinical prospective feasibility study Research Paper

CD90low MSCs modulate intratumoral immunity to confer antitumor activity in a mouse model of ovarian cancer Research Paper

Esophageal 3D organoids of MPV17^-/- mouse model of mitochondrial DNA depletion show epithelial cell plasticity and telomere attrition Research Paper

CD90^low MSCs modulate intratumoral immunity to confer antitumor activity in a mouse model of ovarian cancer Research Paper