The Oncosearch | Oncotarget

Deep learning with deep convolutional neural network using FDG-PET/CT for malignant pleural mesothelioma diagnosis Research Paper

Kazuhiro Kitajima, Hidetoshi Matsuo, Atsushi Kono, Kozo Kuribayashi, Takashi Kijima, Masaki Hashimoto, Seiki Hasegawa, Takamichi Murakami, Koichiro Yamakado

Published May 21, 2021 · Vol. 12, No. 12 · pp. 1187-1196

Keywords: mesothelioma, artificial intelligence, deep learning, FDG (fluorodeoxyglucose), PET-CT (positron emission tomography-computed tomography)

The presence of polymorphisms in genes controlling neurotransmitter metabolism and disease prognosis in patients with prostate cancer: a possible link with schizophrenia Research Paper

Gennady M. Zharinov, Sergei E. Khalchitsky, Alexandre Loktionov, Marina V. Sogoyan, Yulia V. Khutoryanskaya, Natalia Yu. Neklasova, Oleg A. Bogomolov, Ilya V. Smirnov, Marina P. Samoilovich, Vladimir N. Skakun, Sergei V. Vissarionov, Vladimir N. Anisimov

Published Mar 12, 2021 · Vol. 12, No. 7 · pp. 698-707

Keywords: prostate cancer, prostate-specific antigen, disease prognosis, neurotransmitters metabolism genes, psychiatric disorders

Pancreatic cancer driver mutations are targetable through distant alternative RNA splicing dependencies Research Perspective

Ryan R. Kawalerski, Steven D. Leach, Luisa F. Escobar-Hoyos

Published Feb 12, 2021 · Vol. 12, No. 6 · pp. 525-533

Keywords: pancreatic cancer, RNA splicing, targeted therapy, KRAS, TP53

Global DNA hypermethylation pattern and unique gene expression signature in liver cancer from patients with Indigenous American ancestry Research Paper

Juan Pablo Cerapio, Agnès Marchio, Luis Cano, Ignacio López, Jean-Jacques Fournié, Béatrice Régnault, Sandro Casavilca-Zambrano, Eloy Ruiz, Anne Dejean, Stéphane Bertani, Pascal Pineau

Published Feb 3, 2021 · Vol. 12, No. 5 · pp. 475-492

Keywords: hepatitis B virus, indigenous people, integrative genomics, liver cancer

Quantitative proteome profiling stratifies fibroepithelial lesions of the breast Research Paper

Aviral Kumar, David S. Nayakanti, Kiran K. Mangalaparthi, Veena Gopinath, Nandyala Venkat Narsimha Reddy, Krishna Govindan, Geeta Voolapalli, Prashant Kumar, Lekha Dinesh Kumar

Published Feb 3, 2021 · Vol. 12, No. 5 · pp. 507-518

Keywords: breast tumors, fibroepithelial lesions, phyllodes, iTRAQ, quantitative proteomics

Phase 1 study of Z-endoxifen in patients with advanced gynecologic, desmoid, and hormone receptor-positive solid tumors Research Paper

Naoko Takebe, Geraldine O'Sullivan Coyne, Shivaani Kummar, Jerry Collins, Joel M. Reid, Richard Piekarz, Nancy Moore, Lamin Juwara, Barry C. Johnson, Rachel Bishop, Frank I. Lin, Esther Mena, Peter L. Choyke, M. Liza Lindenberg, Larry V. Rubinstein, Cecilia Monge Bonilla, Matthew P. Goetz, Matthew M. Ames, Renee M. McGovern, Howard Streicher, Joseph M. Covey, James H. Doroshow, Alice P. Chen

Published Feb 1, 2021 · Vol. 12, No. 4 · pp. 268-277

Keywords: Z-endoxifen, phase 1, tamoxifen, pharmacokinetics

High mRNA expression of LY6 gene family is associated with overall survival outcome in pancreatic ductal adenocarcinoma Research Paper

Eric Russ, Krithika Bhuvaneshwar, Guisong Wang, Benjamin Jin, Michele M. Gage, Subha Madhavan, Yuriy Gusev, Geeta Upadhyay

Published Jan 26, 2021 · Vol. 12, No. 3 · pp. 145-159

Keywords: LY6 genes, pancreatic cancer, immune cells, survival outcome

The noradrenergic profile of plasma metanephrine in neuroblastoma patients is reproduced in xenograft mice models and arise from PNMT downregulation Research Paper

Karim Abid, Maja Beck Popovic, Katia Balmas Bourloud, Jacqueline Schoumans, Joana Grand-Guillaume, Eric Grouzmann, Annick Mühlethaler-Mottet

Published Dec 23, 2020 · Vol. 12, No. 1 · pp. 49-60

Keywords: neuroblastoma, metanephrine, patient-derived xenograft, mouse model, Phenylethanolamine N-Methyltransferase

Total lesion glycolysis in oral squamous cell carcinoma as a biomarker derived from pre-operative FDG PET/CT outperforms established prognostic factors in a newly developed multivariate prediction model Research Paper

Gerrit Spanier, Daniela Weidt, Dirk Hellwig, Johannes K.H. Meier, Torsten E. Reichert, Jirka Grosse

Published Dec 22, 2020 · Vol. 12, No. 1 · pp. 37-48

Keywords: FDG PET/CT, TLG, MTV, oral squamous cell carcinoma, prognostic value

Standardized diagnostic algorithm for spitzoid lesions aids clinical decision-making and management: a case series from a Swiss reference center Case Report

Marie-Luise Hilbers, Regula Brändli, Beda Mühleisen, Sandra N. Freiberger, Joanna Mangana, Reinhard Dummer

Published Dec 18, 2020 · Vol. 12, No. 2 · pp. 125-130

Keywords: spitzoid nevi, melanocytic lesion, dermatopathology, pediatric dermatology, diagnostic algorithm

MicroRNA-4287 is a novel tumor suppressor microRNA controlling epithelial-to mesenchymal transition in prostate cancer Research Paper

Divya Bhagirath, Thao Ly Yang, Theresa Akoto, Nikhil Patel, Laura Z. Tabatabai, Sharanjot Saini

Published Dec 15, 2020 · Vol. 11, No. 51 · pp. 4681-4692

Keywords: miR-4287, prostate cancer, chromosome 8p, EMT, SLUG

Predictors of immunotherapy benefit in Merkel cell carcinoma Research Paper

Alec J. Kacew, Harita Dharaneeswaran, Gabriel J. Starrett, Manisha Thakuria, Nicole R. LeBoeuf, Ann W. Silk, James A. DeCaprio, Glenn J. Hanna

Published Nov 17, 2020 · Vol. 11, No. 47 · pp. 4401-4410

Keywords: cancer, genomics, immunotherapy, Merkel cell carcinoma, precision medicine

Effect of liver fibrosis on survival in patients with intrahepatic cholangiocarcinoma: a SEER population-based study Research Paper

Nimrod Adatto Levy, Guy Kern, Daniel Shepshelovich, Oren Shibolet, Rami Hershkoviz, Ofer Isakov

Published Nov 11, 2020 · Vol. 11, No. 47 · pp. 4438-4447

Keywords: liver fibrosis, cholangiocarcinoma, SEER, survival, cirrhosis

Serum MACC-1: a new biomarker for breast cancer Research Paper

Meraj Ahmed, Mohammad Aslam

Published Nov 7, 2020 · Vol. 11, No. 48 · pp. 4521-4526

Keywords: serum MACC-1, MACC-1, new biomarker, breast cancer

Intracellular hyaluronic acid-binding protein 4 (HABP4): a candidate tumor suppressor in colorectal cancer Research Paper

Talita Diniz Melo-Hanchuk, Carolina Colleti, Ângela Saito, Maria Carolina Santos Mendes, José Barreto Campello Carvalheira, Jose Vassallo, Jörg Kobarg

Published Nov 4, 2020 · Vol. 11, No. 46 · pp. 4325-4337

Keywords: colon cancer, regulatory protein, gene knockout, proliferation, tumor marker

HER2 splice variants in breast cancer: investigating their impact on diagnosis and treatment outcomes Review

Vic Hart, Hannah Gautrey, John Kirby, Alison Tyson-Capper

Published Oct 22, 2020 · Vol. 11, No. 46 · pp. 4338-4357

Keywords: HER2, Δ16-HER2, splice variant, breast cancer, trastuzumab

Histo-molecular differentiation of renal cancer subtypes by mass spectrometry imaging and rapid proteome profiling of formalin-fixed paraffin-embedded tumor tissue sections Research Paper

Uwe Möginger, Niels Marcussen, Ole N. Jensen

Published Oct 21, 2020 · Vol. 11, No. 44 · pp. 3998-4015

Keywords: renal cell cancer, MALDI mass spectrometry imaging (MALDI MSI), microproteomics, statistical classification, liquid chromatography mass spectrometry (LC-MS)

Biomarkers and novel therapeutic approaches for diffuse large B-cell lymphoma in the era of precision medicine Review

Niraj Lodhi, Moe Tun, Poonam Nagpal, Arati A. Inamdar, Nehad M. Ayoub, Noor Siyam, Lucia Oton-Gonzalez, Angela Gerona, Dainelle Morris, Rana Sandhu, Kwangsun Stephen Suh

Published Oct 20, 2020 · Vol. 11, No. 44 · pp. 4045-4073

Keywords: DLBCL, diagnosis, R-CHOP, precision medicine, prognosis

Phase I trial of TRC102 (methoxyamine HCl) in combination with temozolomide in patients with relapsed solid tumors and lymphomas Research Paper

Geraldine O'Sullivan Coyne, Shivaani Kummar, Robert S. Meehan, Khanh Do, Jerry M. Collins, Larry Anderson, Kazusa Ishii, Naoko Takebe, Jennifer Zlott, Lamin Juwara, Richard Piekarz, Howard Streicher, Elad Sharon, Larry Rubinstein, Andrea Regier Voth, Jay Lozier, Angie B. Dull, Deborah Wilsker, Toshinori Hinoue, Peter W. Laird, Katherine V. Ferry-Galow, Robert J. Kinders, Ralph E. Parchment, James H. Doroshow, Alice P. Chen

Published Oct 12, 2020 · Vol. 11, No. 44 · pp. 3959-3971

Keywords: DNA damage repair, base excision repair, MGMT, rational combination therapy, molecular pharmacodynamics

Estrogen receptor α polymorphism is associated with dementia in a Brazilian cohort Research Paper

Rafaella Papalino Lopes Magnago, Valerio Garrone Barauna, Bruna Ferro Brun, Ana Cristina Lo Prete, Aline Morgan Alvarenga, Luciene C. Gastalho Campos, Neuza Felix Gomes Rochette, Letícia Batista Azevedo Rangel, Rodrigo Alves Faria, Paulo Caleb Junior Lima Santos, Ian Victor Silva

Published Sep 4, 2020 · Vol. 11, No. 50 · pp. 4655-4660

Keywords: dementia, elderly, estrogen receptor α, polymorphism

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Deep learning with deep convolutional neural network using FDG-PET/CT for malignant pleural mesothelioma diagnosis Research Paper

The presence of polymorphisms in genes controlling neurotransmitter metabolism and disease prognosis in patients with prostate cancer: a possible link with schizophrenia Research Paper

Pancreatic cancer driver mutations are targetable through distant alternative RNA splicing dependencies Research Perspective

Global DNA hypermethylation pattern and unique gene expression signature in liver cancer from patients with Indigenous American ancestry Research Paper

Quantitative proteome profiling stratifies fibroepithelial lesions of the breast Research Paper

Phase 1 study of Z-endoxifen in patients with advanced gynecologic, desmoid, and hormone receptor-positive solid tumors Research Paper

High mRNA expression of LY6 gene family is associated with overall survival outcome in pancreatic ductal adenocarcinoma Research Paper

The noradrenergic profile of plasma metanephrine in neuroblastoma patients is reproduced in xenograft mice models and arise from PNMT downregulation Research Paper

Total lesion glycolysis in oral squamous cell carcinoma as a biomarker derived from pre-operative FDG PET/CT outperforms established prognostic factors in a newly developed multivariate prediction model Research Paper

Standardized diagnostic algorithm for spitzoid lesions aids clinical decision-making and management: a case series from a Swiss reference center Case Report

MicroRNA-4287 is a novel tumor suppressor microRNA controlling epithelial-to mesenchymal transition in prostate cancer Research Paper

Predictors of immunotherapy benefit in Merkel cell carcinoma Research Paper

Effect of liver fibrosis on survival in patients with intrahepatic cholangiocarcinoma: a SEER population-based study Research Paper

Serum MACC-1: a new biomarker for breast cancer Research Paper

Intracellular hyaluronic acid-binding protein 4 (HABP4): a candidate tumor suppressor in colorectal cancer Research Paper

HER2 splice variants in breast cancer: investigating their impact on diagnosis and treatment outcomes Review

Histo-molecular differentiation of renal cancer subtypes by mass spectrometry imaging and rapid proteome profiling of formalin-fixed paraffin-embedded tumor tissue sections Research Paper

Biomarkers and novel therapeutic approaches for diffuse large B-cell lymphoma in the era of precision medicine Review

Phase I trial of TRC102 (methoxyamine HCl) in combination with temozolomide in patients with relapsed solid tumors and lymphomas Research Paper

Estrogen receptor α polymorphism is associated with dementia in a Brazilian cohort Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Deep learning with deep convolutional neural network using FDG-PET/CT for malignant pleural mesothelioma diagnosis Research Paper

The presence of polymorphisms in genes controlling neurotransmitter metabolism and disease prognosis in patients with prostate cancer: a possible link with schizophrenia Research Paper

Pancreatic cancer driver mutations are targetable through distant alternative RNA splicing dependencies Research Perspective

Global DNA hypermethylation pattern and unique gene expression signature in liver cancer from patients with Indigenous American ancestry Research Paper

Quantitative proteome profiling stratifies fibroepithelial lesions of the breast Research Paper

Phase 1 study of Z-endoxifen in patients with advanced gynecologic, desmoid, and hormone receptor-positive solid tumors Research Paper

High mRNA expression of LY6 gene family is associated with overall survival outcome in pancreatic ductal adenocarcinoma Research Paper

The noradrenergic profile of plasma metanephrine in neuroblastoma patients is reproduced in xenograft mice models and arise from PNMT downregulation Research Paper

Total lesion glycolysis in oral squamous cell carcinoma as a biomarker derived from pre-operative FDG PET/CT outperforms established prognostic factors in a newly developed multivariate prediction model Research Paper

Standardized diagnostic algorithm for spitzoid lesions aids clinical decision-making and management: a case series from a Swiss reference center Case Report

MicroRNA-4287 is a novel tumor suppressor microRNA controlling epithelial-to mesenchymal transition in prostate cancer Research Paper

Predictors of immunotherapy benefit in Merkel cell carcinoma Research Paper

Effect of liver fibrosis on survival in patients with intrahepatic cholangiocarcinoma: a SEER population-based study Research Paper

Serum MACC-1: a new biomarker for breast cancer Research Paper

Intracellular hyaluronic acid-binding protein 4 (HABP4): a candidate tumor suppressor in colorectal cancer Research Paper

HER2 splice variants in breast cancer: investigating their impact on diagnosis and treatment outcomes Review

Histo-molecular differentiation of renal cancer subtypes by mass spectrometry imaging and rapid proteome profiling of formalin-fixed paraffin-embedded tumor tissue sections Research Paper

Biomarkers and novel therapeutic approaches for diffuse large B-cell lymphoma in the era of precision medicine Review

Phase I trial of TRC102 (methoxyamine HCl) in combination with temozolomide in patients with relapsed solid tumors and lymphomas Research Paper

Estrogen receptor α polymorphism is associated with dementia in a Brazilian cohort Research Paper