The Oncosearch | Oncotarget

Combined treatment with niclosamide and camptothecin enhances anticancer effect in U87 MG human glioblastoma cells Research Paper

Laura Valdez, Benxu Cheng, Daniela Gonzalez, Reanna Rodriguez, Paola Campano, Andrew Tsin, Xiaoqian Fang

Published Apr 22, 2022 · Vol. 13, No. 1 · pp. 642-658

Keywords: glioblastoma, niclosamide, camptothecin, cancer, chemotherapy

Patient-derived tumor models are attractive tools to repurpose drugs for ovarian cancer treatment: pre-clinical updates Review

Magdalena Cybula, Magdalena Bieniasz

Published Mar 11, 2022 · Vol. 13, No. 1 · pp. 553-575

Keywords: PDX, ovarian cancer, repurposed drugs, tumor models

Transplantation of autologous bone marrow pre-loaded ex vivo with oncolytic myxoma virus is efficacious against drug-resistant Vk*MYC mouse myeloma Research Paper

Nancy Y. Villa, Masmudur M. Rahman, Joseph Mamola, Meaghen E. Sharik, Ana Lemos de Matos, Jacquelyn Kilbourne, Kenneth Lowe, Juliane Daggett-Vondras, Julia D'Isabella, Elizabeth Goras, Marta Chesi, P. Leif Bergsagel, Grant McFadden

Published Feb 21, 2022 · Vol. 13, No. 1 · pp. 490-504

Keywords: myxoma virus, multiple myeloma, combination therapy, autologous transplantation, oncolytic virus

NOTCH1 PEST domain variants are responsive to standard of care treatments despite distinct transformative properties in a breast cancer model Research Paper

Karen Cravero, Morgan V. Pantone, Dong Ho Shin, Riley Bergman, Rory Cochran, David Chu, Daniel J. Zabransky, Swathi Karthikeyan, Ian G. Waters, Natasha Hunter, D. Marc Rosen, Kelly Kyker-Snowman, W. Brian Dalton, Berry Button, Dan Shinn, Hong Yuen Wong, Joshua Donaldson, Paula J. Hurley, Sarah Croessmann, Ben Ho Park

Published Feb 11, 2022 · Vol. 13, No. 1 · pp. 373-386

Keywords: NOTCH1, TNBC, breast cancer, PEST

Plasma biomarkers reflecting high oxidative stress in the prediction of myocardial injury due to anthracycline chemotherapy and the effect of carvedilol: insights from the CECCY Trial Research Paper

Mauro Rogério de Barros Wanderley Jr., Mônica Samuel Ávila, Miguel Morita Fernandes-Silva, Fátima das Dores Cruz, Sara Michelly Gonçalves Brandão, Vagner Oliveira Carvalho Rigaud, Ludhmila Abrahão Hajjar, Roberto Kalil Filho, Edécio Cunha-Neto, Edimar Alcides Bocchi, Silvia Moreira Ayub-Ferreira

Published Jan 20, 2022 · Vol. 13, No. 1 · pp. 214-223

Keywords: cardiotoxicity, biomarkers, myeloperoxidase, galectin-3, anthracyclines

Early detection of treatment futility in patients with metastatic colorectal cancer Research Paper

Jodi I. Rattner, Karen A. Kopciuk, Hans J. Vogel, Patricia A. Tang, Jeremy D. Shapiro, Dongsheng Tu, Derek J. Jonker, Lillian L. Siu, Chris J. O’Callaghan, Oliver F. Bathe

Published Dec 21, 2021 · Vol. 13, No. 1 · pp. 61-72

Keywords: colorectal cancer, metabolomics, response biomarkers, radiographic imaging, chemotherapy

Transcriptomics reveals in vivo efficacy of PARP inhibitor combinatorial synergy with platinum-based chemotherapy in human non-small cell lung carcinoma models Research Paper

Lindsay R. Stolzenburg, Barrett Ainsworth, Bridget Riley-Gillis, Tibor Pakozdi, Areej Ammar, Paul A. Ellis, Julie L. Wilsbacher, Cyril Y. Ramathal

Published Dec 17, 2021 · Vol. 13, No. 1 · pp. 1-12

Keywords: PARP inhibitor, veliparib, cisplatin, transcriptomics, NSCLC

The clinician’s perspective on the 21-gene assay in early breast cancer Review

Francesco Cognetti, Giuseppe Naso

Published Dec 1, 2021 · Vol. 12, No. 26 · pp. 2514-2530

Keywords: Oncotype DX test, recurrence score results, multigene assays, genomic tests, personalized medicine

Circulating low density neutrophils of breast cancer patients are associated with their worse prognosis due to the impairment of T cell responses Research Paper

Diana P. Saraiva, Bruna F. Correia, Rute Salvador, Nídia de Sousa, António Jacinto, Sofia Braga, M. Guadalupe Cabral

Published Nov 15, 2021 · Vol. 12, No. 24 · pp. 2388-2403

Keywords: breast cancer, chemotherapy response, tumor-associated neutrophils, low density neutrophils, biomarker

Emerging approaches of wound healing in experimental models of high-grade oral mucositis induced by anticancer therapy Review

Ana Chor, Maria Adriana Skeff, Christina Takiya, Raquel Gonçalves, Marcos Dias, Marcos Farina, Leonardo R. Andrade, Valeria de Mello Coelho

Published Oct 1, 2021 · Vol. 12, No. 22 · pp. 2283-2299

Keywords: oral mucositis, inflammation, regeneration, polymers, tissue engineering

P10s-PADRE vaccine combined with neoadjuvant chemotherapy in ER-positive breast cancer patients induces humoral and cellular immune responses Research Paper

Issam Makhoul, Saddam Mohammed Ibrahim, Muhammad Abu-Rmaileh, Fariba Jousheghany, Eric R. Siegel, Lora J. Rogers, John J. Lee, Sergio Pina-Oviedo, Ginell R. Post, J. Thaddeus Beck, Thomas Kieber-Emmons, Behjatolah Monzavi-Karbassi

Published Sep 16, 2021 · Vol. 12, No. 22 · pp. 2252-2265

Keywords: cancer vaccine, peptide mimotopes, combination therapy, breast cancer

Pan-drug and drug-specific mechanisms of 5-FU, irinotecan (CPT-11), oxaliplatin, and cisplatin identified by comparison of transcriptomic and cytokine responses of colorectal cancer cells Research Paper

Lindsey Carlsen, Christoph Schorl, Kelsey Huntington, Liz Hernandez-Borrero, Aakash Jhaveri, Shengliang Zhang, Lanlan Zhou, Wafik S. El-Deiry

Published Sep 8, 2021 · Vol. 12, No. 20 · pp. 2006-2021

Keywords: chemotherapy mechanism, colon cancer, 5-fluorouracil, irinotecan, oxaliplatin

Tissue biodistribution and tumor targeting of near-infrared labelled anti-CD38 antibody-drug conjugate in preclinical multiple myeloma Research Paper

Nicholas Cho, Sooah Ko, Monica Shokeen

Published Sep 7, 2021 · Vol. 12, No. 20 · pp. 2039-2050

Keywords: near-infrared (NIR) fluorescence, multiple myeloma (MM), cluster of differentiation 38 (CD38), antibody-drug conjugate (ADC), small animal optical imaging

Exploratory comparisons between different anti-mitotics in clinically-used drug combination in triple negative breast cancer Research Paper

Bruna Cândido Guido, Douglas Cardoso Brandão, Ana Luisa Augusto Barbosa, Monique Jacob Xavier Vianna, Lucas Faro, Luciana Machado Ramos, Fabíola Nihi, Márcio Botelho de Castro, Brenno A.D. Neto, José Raimundo Corrêa, Sônia Nair Báo

Published Aug 27, 2021 · Vol. 12, No. 19 · pp. 1920-1936

Keywords: KIF11 inhibition, Kinesin Eg5, breast cancer, adjuvant treatment, cancer progression

Polyclonal on- and off-target resistance mutations in an EML4-ALK positive non-small cell lung cancer patient under ALK inhibition Case Report

Marcel Kemper, Georg Evers, Arik Bernard Schulze, Jan Sperveslage, Christoph Schülke, Georg Lenz, Thomas Herold, Wolfgang Hartmann, Hans-Ulrich Schildhaus, Annalen Bleckmann

Published Aug 23, 2021 · Vol. 12, No. 19 · pp. 1946-1952

Keywords: NSCLC, resistance mutations, ALK, KRAS, ALK inhibitors

Normal tissue and tumor microenvironment adaptations to aerobic exercise enhance doxorubicin anti-tumor efficacy and ameliorate its cardiotoxicity in retired breeder mice Priority Research Paper

Zachary R. Wakefield, Mai Tanaka, Christine Pampo, Sharon Lepler, Lori Rice, Joy Guingab-Cagmat, Timothy J. Garrett, Dietmar W. Siemann

Published Aug 18, 2021 · Vol. 12, No. 18 · pp. 1737-1748

Keywords: aerobic exercise, breast cancer, hypoxia, doxorubicin, cardiotoxicity

Pim kinase inhibitor co-treatment decreases alternative non-homologous end-joining DNA repair and genomic instability induced by topoisomerase 2 inhibitors in cells with FLT3 internal tandem duplication Research Paper

Mario Scarpa, Shivani Kapoor, Eric S. Tvedte, Kshama A. Doshi, Ying S. Zou, Prerna Singh, Jonelle K. Lee, Aditi Chatterjee, Moaath K. Mustafa Ali, Robin E. Bromley, Julie C. Dunning Hotopp, Feyruz V. Rassool, Maria R. Baer

Published Aug 2, 2021 · Vol. 12, No. 18 · pp. 1763-1779

Keywords: FLT3 internal tandem duplication, Pim kinase, alternative non-homologous end-joining DNA repair, genomic instability, topoisomerase 2 inhibitors

Neddylation and anti-tumor immunity Research Perspective

Xiaoguang Wang, Scott Best, Alexey V. Danilov

Published Jun 27, 2021 · Vol. 12, No. 21 · pp. 2227-2230

Keywords: neddylation, T cell, pevonedistat

MRI texture features from tumor core and margin in the prediction of response to neoadjuvant chemotherapy in patients with locally advanced breast cancer Research Paper

Christopher Kolios, Lakshmanan Sannachi, Archya Dasgupta, Harini Suraweera, Daniel DiCenzo, Gregory Stanisz, Arjun Sahgal, Frances Wright, Nicole Look-Hong, Belinda Curpen, Ali Sadeghi-Naini, Maureen Trudeau, Sonal Gandhi, Michael C. Kolios, Gregory J. Czarnota

Published Jun 16, 2021 · Vol. 12, No. 14 · pp. 1354-1365

Keywords: radiomics, MRI, breast cancer, neoadjuvant chemotherapy, biomarkers

Human papilloma virus circulating tumor DNA assay predicts treatment response in recurrent/metastatic head and neck squamous cell carcinoma Research Paper

Catherine T. Haring, Chandan Bhambhani, Collin Brummel, Brittany Jewell, Emily Bellile, Molly E. Heft Neal, Erin Sandford, Ryan M. Spengler, Apurva Bhangale, Matthew E. Spector, Jonathan McHugh, Mark E. Prince, Michelle Mierzwa, Francis P. Worden, Muneesh Tewari, Paul L. Swiecicki, J. Chad Brenner

Published Jun 11, 2021 · Vol. 12, No. 13 · pp. 1214-1229

Keywords: HPV, head and neck cancer, oropharyngeal cancer, ctDNA, circulating tumor DNA

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Combined treatment with niclosamide and camptothecin enhances anticancer effect in U87 MG human glioblastoma cells Research Paper

Patient-derived tumor models are attractive tools to repurpose drugs for ovarian cancer treatment: pre-clinical updates Review

Transplantation of autologous bone marrow pre-loaded ex vivo with oncolytic myxoma virus is efficacious against drug-resistant Vk*MYC mouse myeloma Research Paper

NOTCH1 PEST domain variants are responsive to standard of care treatments despite distinct transformative properties in a breast cancer model Research Paper

Plasma biomarkers reflecting high oxidative stress in the prediction of myocardial injury due to anthracycline chemotherapy and the effect of carvedilol: insights from the CECCY Trial Research Paper

Early detection of treatment futility in patients with metastatic colorectal cancer Research Paper

Transcriptomics reveals in vivo efficacy of PARP inhibitor combinatorial synergy with platinum-based chemotherapy in human non-small cell lung carcinoma models Research Paper

The clinician’s perspective on the 21-gene assay in early breast cancer Review

Circulating low density neutrophils of breast cancer patients are associated with their worse prognosis due to the impairment of T cell responses Research Paper

Emerging approaches of wound healing in experimental models of high-grade oral mucositis induced by anticancer therapy Review

P10s-PADRE vaccine combined with neoadjuvant chemotherapy in ER-positive breast cancer patients induces humoral and cellular immune responses Research Paper

Pan-drug and drug-specific mechanisms of 5-FU, irinotecan (CPT-11), oxaliplatin, and cisplatin identified by comparison of transcriptomic and cytokine responses of colorectal cancer cells Research Paper

Tissue biodistribution and tumor targeting of near-infrared labelled anti-CD38 antibody-drug conjugate in preclinical multiple myeloma Research Paper

Exploratory comparisons between different anti-mitotics in clinically-used drug combination in triple negative breast cancer Research Paper

Polyclonal on- and off-target resistance mutations in an EML4-ALK positive non-small cell lung cancer patient under ALK inhibition Case Report

Normal tissue and tumor microenvironment adaptations to aerobic exercise enhance doxorubicin anti-tumor efficacy and ameliorate its cardiotoxicity in retired breeder mice Priority Research Paper

Pim kinase inhibitor co-treatment decreases alternative non-homologous end-joining DNA repair and genomic instability induced by topoisomerase 2 inhibitors in cells with FLT3 internal tandem duplication Research Paper

Neddylation and anti-tumor immunity Research Perspective

MRI texture features from tumor core and margin in the prediction of response to neoadjuvant chemotherapy in patients with locally advanced breast cancer Research Paper

Human papilloma virus circulating tumor DNA assay predicts treatment response in recurrent/metastatic head and neck squamous cell carcinoma Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Combined treatment with niclosamide and camptothecin enhances anticancer effect in U87 MG human glioblastoma cells Research Paper

Patient-derived tumor models are attractive tools to repurpose drugs for ovarian cancer treatment: pre-clinical updates Review

Transplantation of autologous bone marrow pre-loaded ex vivo with oncolytic myxoma virus is efficacious against drug-resistant Vk*MYC mouse myeloma Research Paper

NOTCH1 PEST domain variants are responsive to standard of care treatments despite distinct transformative properties in a breast cancer model Research Paper

Plasma biomarkers reflecting high oxidative stress in the prediction of myocardial injury due to anthracycline chemotherapy and the effect of carvedilol: insights from the CECCY Trial Research Paper

Early detection of treatment futility in patients with metastatic colorectal cancer Research Paper

Transcriptomics reveals in vivo efficacy of PARP inhibitor combinatorial synergy with platinum-based chemotherapy in human non-small cell lung carcinoma models Research Paper

The clinician’s perspective on the 21-gene assay in early breast cancer Review

Circulating low density neutrophils of breast cancer patients are associated with their worse prognosis due to the impairment of T cell responses Research Paper

Emerging approaches of wound healing in experimental models of high-grade oral mucositis induced by anticancer therapy Review

P10s-PADRE vaccine combined with neoadjuvant chemotherapy in ER-positive breast cancer patients induces humoral and cellular immune responses Research Paper

Pan-drug and drug-specific mechanisms of 5-FU, irinotecan (CPT-11), oxaliplatin, and cisplatin identified by comparison of transcriptomic and cytokine responses of colorectal cancer cells Research Paper

Tissue biodistribution and tumor targeting of near-infrared labelled anti-CD38 antibody-drug conjugate in preclinical multiple myeloma Research Paper

Exploratory comparisons between different anti-mitotics in clinically-used drug combination in triple negative breast cancer Research Paper

Polyclonal on- and off-target resistance mutations in an EML4-ALK positive non-small cell lung cancer patient under ALK inhibition Case Report

Normal tissue and tumor microenvironment adaptations to aerobic exercise enhance doxorubicin anti-tumor efficacy and ameliorate its cardiotoxicity in retired breeder mice Priority Research Paper

Pim kinase inhibitor co-treatment decreases alternative non-homologous end-joining DNA repair and genomic instability induced by topoisomerase 2 inhibitors in cells with FLT3 internal tandem duplication Research Paper

Neddylation and anti-tumor immunity Research Perspective

MRI texture features from tumor core and margin in the prediction of response to neoadjuvant chemotherapy in patients with locally advanced breast cancer Research Paper

Human papilloma virus circulating tumor DNA assay predicts treatment response in recurrent/metastatic head and neck squamous cell carcinoma Research Paper