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Cooperative interactions between p53 and NFκB enhance cell plasticity Research Paper
Keywords: p53, NFkB, chemotherapy, doxorubicin, TNFï¡ï€» EMT, synergy, breast cancer
RYBP expression is associated with better survival of patients with hepatocellular carcinoma (HCC) and responsiveness to chemotherapy of HCC cells in vitro and in vivo Research Paper
High Id1 expression, a generally negative prognostic factor, paradoxically predicts a favorable prognosis for adjuvant paclitaxel plus cisplatin therapy in surgically treated lung cancer patients Research Paper
Suppression of esophageal tumor growth and chemoresistance by directly targeting the PI3K/AKT pathway Research Paper
Senescence of tumor cells induced by oxaliplatin increases the efficiency of a lipid A immunotherapy via the recruitment of neutrophils Research Paper
Fas signaling promotes chemoresistance in gastrointestinal cancer by up-regulating P-glycoprotein Research Paper
Chemoradiation provides a physiological selective pressure that increases the expansion of aberrant TP53 tumor variants in residual rectal cancerous regions Clinical Research Papers
Overexpression of IFN-induced protein with tetratricopeptide repeats 3 (IFIT3) in pancreatic cancer: cellular “pseudoinflammation†contributing to an aggressive phenotype Research Paper
Targeting the DNA replication checkpoint by pharmacologic inhibition of Chk1 kinase: a strategy to sensitize APC mutant colon cancer cells to 5-fluorouracil chemotherapy Research Paper
HSP90 inhibition downregulates thymidylate synthase and sensitizes colorectal cancer cell lines to the effect of 5FU-based chemotherapy Research Paper
Melanoma-initiating cells exploit M2 macrophage TGFβ and arginase pathway for survival and proliferation Research Paper
Inhibition of SphK1 reduces radiation-induced migration and enhances sensitivity to cetuximab treatment by affecting the EGFR / SphK1 crosstalk Research Paper
The Hippo transducer TAZ as a biomarker of pathological complete response in HER2-positive breast cancer patients treated with trastuzumab-based neoadjuvant therapy Clinical Research Papers
Dihydromyricetin prevents cardiotoxicity and enhances anticancer activity induced by adriamycin Research Paper
CUSP9* treatment protocol for recurrent glioblastoma: aprepitant, artesunate, auranofin, captopril, celecoxib, disulfiram, itraconazole, ritonavir, sertraline augmenting continuous low dose temozolomide Research Perspective
Plerixafor as a chemosensitizing agent in pediatric acute lymphoblastic leukemia: efficacy and potential mechanisms of resistance to CXCR4 inhibition Clinical Research Papers
A first in man phase I trial of the oral immunomodulator, indoximod, combined with docetaxel in patients with metastatic solid tumors Clinical Research Papers
Keywords: Indoximod, 1-methyl-D-tryptophan, immunomodulator, docetaxel, indoleamine 2, 3 dioxygenase