The Oncosearch | Oncotarget

Ibuprofen disrupts a WNK1/GSK3β/SRPK1 protein complex required for expression of tumor-related splicing variant RAC1B in colorectal cells Research Paper

Vânia Gonçalves, Andreia F.A. Henriques, Paulo Matos, Peter Jordan

Published Nov 9, 2020 · Vol. 11, No. 47 · pp. 4421-4437

Keywords: ibuprofen, protein kinase, RAC1B, alternative splicing, colorectal cancer cells

HIC1 (Hypermethylated in Cancer 1) modulates the contractile activity of prostate stromal fibroblasts and directly regulates CXCL12 expression Research Paper

Marion Dubuissez, Sonia Paget, Souhila Abdelfettah, Nathalie Spruyt, Vanessa Dehennaut, Gaylor Boulay, Ingrid Loison, Clementine de Schutter, Brian R. Rood, Martine Duterque-Coquillaud, Xavier Leroy, Dominique Leprince

Published Oct 21, 2020 · Vol. 11, No. 45 · pp. 4138-4154

Keywords: HIC1, CXCL12, SDF1, α-SMA, Acta2

Anti-tumor activities of the new oral pan-RAF inhibitor, TAK-580, used as monotherapy or in combination with novel agents in multiple myeloma Research Paper

Rikio Suzuki, Yuka Kitamura, Yoshihiko Nakamura, Hibiki Akashi, Yoshiaki Ogawa, Hiroshi Kawada, Kiyoshi Ando

Published Oct 7, 2020 · Vol. 11, No. 44 · pp. 3984-3997

Keywords: pan-RAF inhibitor, Bim, FOXO3a, bortezomib, lenalidomide

KDM5A and PHF2 positively control expression of pro-metastatic genes repressed by EWS/Fli1, and promote growth and metastatic properties in Ewing sarcoma Research Paper

Tyler S. McCann, Janet K. Parrish, Joseph Hsieh, Marybeth Sechler, Lays M. Sobral, Chelsea Self, Kenneth L. Jones, Andrew Goodspeed, James C. Costello, Paul Jedlicka

Published Aug 29, 2020 · Vol. 11, No. 43 · pp. 3818-3831

Keywords: Ewing sarcoma, metastasis, epigenetics, Jumonji-domain histone demethylase

Targeted lymphodepletion with a CD45-directed antibody radioconjugate as a novel conditioning regimen prior to adoptive cell therapy Research Paper

Wojciech Dawicki, Kevin J.H. Allen, Ravendra Garg, Eileen M. Geoghegan, Mark S. Berger, Dale L. Ludwig, Ekaterina Dadachova

Published Aug 26, 2020 · Vol. 11, No. 39 · pp. 3571-3581

Keywords: anti-CD45 targeted lymphodepletion, radioimmunotherapy, adoptive cell therapy, 131Iodine, 177Lutetium

Altered lung tissue lipidomic profile in caspase-4 positive non-small cell lung cancer (NSCLC) patients Research Paper

Michela Terlizzi, Antonio Molino, Chiara Colarusso, Pasquale Somma, Ilaria De Rosa, Jacopo Troisi, Giovanni Scala, Rosario Salvi, Aldo Pinto, Rosalinda Sorrentino

Published Aug 19, 2020 · Vol. 11, No. 38 · pp. 3515-3525

Keywords: NSCLC, metabolomic, lipidomic, metabotype, caspase-4

ATM inhibition overcomes resistance to histone deacetylase inhibitor due to p21 induction and cell cycle arrest Research Paper

Luigi Scotto, Xavier J. Serrano, Kelly Zullo, Cristina Kinahan, Changchun Deng, Ahmed Sawas, Susan Bates, Owen A. O’Connor

Published Aug 18, 2020 · Vol. 11, No. 37 · pp. 3432-3442

Keywords: lymphoma, HDAC inhibitor, ATM inhibitor, p21, cell cycle

Preclinical evaluation of the anti-tumor activity of pralatrexate in high-risk neuroblastoma cells Research Paper

Rachael A. Clark, Sora Lee, Jingbo Qiao, Dai H. Chung

Published Jul 23, 2020 · Vol. 11, No. 32 · pp. 3069-3077

Keywords: neuroblastoma, pralatrexate, N-myc, folate metabolism

Panaxynol, a bioactive component of American ginseng, targets macrophages and suppresses colitis in mice Priority Research Paper

Anusha Chaparala, Deepak Poudyal, Hossam Tashkandi, Erin E. Witalison, Alexander A. Chumanevich, Jenna L. Hofseth, Ivy Nguyen, Olivia Hardy, Douglas L. Pittman, Michael D. Wyatt, Anthony Windust, Elizabeth A. Murphy, Mitzi Nagarkatti, Prakash Nagarkatti, Lorne J. Hofseth

Published Apr 30, 2020 · Vol. 11, No. 22 · pp. 2026-2036

Keywords: inflammatory bowel diseases, ulcerative colitis, American ginseng, panaxynol, macrophages

Clinical implications of chromatin accessibility in human cancers Research Paper

Yuexin Liu

Published Apr 22, 2020 · Vol. 11, No. 18 · pp. 1666-1678

Keywords: ATAC-seq, chromatin accessibility, TCGA, promoter, survival

Synergistic combinations of paclitaxel and withaferin A against human non-small cell lung cancer cells Research Paper

Al Hassan Kyakulaga, Farrukh Aqil, Radha Munagala, Ramesh C. Gupta

Published Apr 21, 2020 · Vol. 11, No. 16 · pp. 1399-1416

Keywords: non-small cell lung cancer, withaferin A, synergistic, combination index, paclitaxel

Investigation of the role of VHL-HIF signaling in DNA repair and apoptosis in zebrafish Research Paper

Hyejeong Rosemary Kim, Kirankumar Santhakumar, Eleanor Markham, Davide Baldera, David Greenald, Helen E. Bryant, Sherif F. El-Khamisy, Fredericus J. van Eeden

Published Mar 31, 2020 · Vol. 11, No. 13 · pp. 1109-1130

Keywords: Hif, Vhl, DNA repair, apoptosis, chemo/radio-resistance

hPCL3S promotes proliferation and migration of androgen-independent prostate cancer cells Research Paper

Souhila Abdelfettah, Gaylor Boulay, Marion Dubuissez, Nathalie Spruyt, Sara P. Garcia, Shruthi Rengarajan, Ingrid Loison, Xavier Leroy, Miguel N. Rivera, Dominique Leprince

Published Mar 24, 2020 · Vol. 11, No. 12 · pp. 1051-1074

Keywords: hPCL3S, PHF19, PRC2, β-catenin, prostate cancer

Acute promyelocytic leukemia (APL): a review of the literature Review

Joaquin J. Jimenez, Ravinder S. Chale, Andrea C. Abad, Andrew V. Schally

Published Mar 17, 2020 · Vol. 11, No. 11 · pp. 992-1003

Keywords: promyelocytic leukemia, arsenic trioxide, retinoic acid, resistance

Mifamurtide and TAM-like macrophages: effect on proliferation, migration and differentiation of osteosarcoma cells Research Paper

Francesca Punzo, Giulia Bellini, Chiara Tortora, Daniela Di Pinto, Maura Argenziano, Elvira Pota, Alessandra Di Paola, Martina Di Martino, Francesca Rossi

Published Feb 18, 2020 · Vol. 11, No. 7 · pp. 687-698

Keywords: macrophage polarization, tumor micro-environment, osteosarcoma, Mifamurtide, MG63

Tumor suppressor genes and allele-specific expression: mechanisms and significance Research Paper

Evan A. Clayton, Shareef Khalid, Dongjo Ban, Lu Wang, I. King Jordan, John F. McDonald

Published Jan 28, 2020 · Vol. 11, No. 4 · pp. 462-479

Keywords: allele-specific expression, alternative splicing, antisense RNA, cancer, tumor-suppressor genes

Cetuximab is efficient and safe in patients with advanced cutaneous squamous cell carcinoma: a retrospective, multicentre study Research Paper

Henri Montaudié, Julien Viotti, Patrick Combemale, Caroline Dutriaux, Nicolas Dupin, Caroline Robert, Laurent Mortier, Régis Kaphan, Anne-Bénédicte Duval-Modeste, Stéphane Dalle, Julie De Quatrebarbes, Andrea Stefan, Florence Brunet-Possenti, Maria Kogay, Alexandra Picard-Gauci, Gilles Poissonnet, Frédéric Peyrade

Published Jan 28, 2020 · Vol. 11, No. 4 · pp. 378-385

Keywords: cutaneous squamous cell carcinoma, cetuximab, epidermal growth factor receptor

Circulating tumor DNA analysis in the era of precision oncology Review

Rabih Said, Nicolas Guibert, Geoffrey R. Oxnard, Apostolia M. Tsimberidou

Published Jan 14, 2020 · Vol. 11, No. 2 · pp. 188-211

Keywords: circulating tumor DNA analysis, clinical trials, targeted therapy, genomic profiling

A squalamine derivative, NV669, as a novel PTP1B inhibitor: in vitro and in vivo effects on pancreatic and hepatic tumor growth Research Paper

Sylvie Carmona, Jean-Michel Brunel, Rénaté Bonier, Véronique Sbarra, Stéphane Robert, Patrick Borentain, Dominique Lombardo, Eric Mas, René Gerolami

Published Nov 19, 2019 · Vol. 10, No. 62 · pp. 6651-6667

Keywords: aminosterol, pancreas, liver, PTP1B, cancer

Correction: FGFR1β is a driver isoform of FGFR1 alternative splicing in breast cancer cells Correction

Ming Zhao, Ming-Lei Zhuo, Xiaofeng Zheng, Xiaoping Su, Funda Meric-Bernstam

Published Nov 16, 2019 · Vol. 10, No. 65 · pp. 7014-7015

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Ibuprofen disrupts a WNK1/GSK3β/SRPK1 protein complex required for expression of tumor-related splicing variant RAC1B in colorectal cells Research Paper

HIC1 (Hypermethylated in Cancer 1) modulates the contractile activity of prostate stromal fibroblasts and directly regulates CXCL12 expression Research Paper

Anti-tumor activities of the new oral pan-RAF inhibitor, TAK-580, used as monotherapy or in combination with novel agents in multiple myeloma Research Paper

KDM5A and PHF2 positively control expression of pro-metastatic genes repressed by EWS/Fli1, and promote growth and metastatic properties in Ewing sarcoma Research Paper

Targeted lymphodepletion with a CD45-directed antibody radioconjugate as a novel conditioning regimen prior to adoptive cell therapy Research Paper

Altered lung tissue lipidomic profile in caspase-4 positive non-small cell lung cancer (NSCLC) patients Research Paper

ATM inhibition overcomes resistance to histone deacetylase inhibitor due to p21 induction and cell cycle arrest Research Paper

Preclinical evaluation of the anti-tumor activity of pralatrexate in high-risk neuroblastoma cells Research Paper

Panaxynol, a bioactive component of American ginseng, targets macrophages and suppresses colitis in mice Priority Research Paper

Clinical implications of chromatin accessibility in human cancers Research Paper

Synergistic combinations of paclitaxel and withaferin A against human non-small cell lung cancer cells Research Paper

Investigation of the role of VHL-HIF signaling in DNA repair and apoptosis in zebrafish Research Paper

hPCL3S promotes proliferation and migration of androgen-independent prostate cancer cells Research Paper

Acute promyelocytic leukemia (APL): a review of the literature Review

Mifamurtide and TAM-like macrophages: effect on proliferation, migration and differentiation of osteosarcoma cells Research Paper

Tumor suppressor genes and allele-specific expression: mechanisms and significance Research Paper

Cetuximab is efficient and safe in patients with advanced cutaneous squamous cell carcinoma: a retrospective, multicentre study Research Paper

Circulating tumor DNA analysis in the era of precision oncology Review

A squalamine derivative, NV669, as a novel PTP1B inhibitor: in vitro and in vivo effects on pancreatic and hepatic tumor growth Research Paper

Correction: FGFR1β is a driver isoform of FGFR1 alternative splicing in breast cancer cells Correction

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Ibuprofen disrupts a WNK1/GSK3β/SRPK1 protein complex required for expression of tumor-related splicing variant RAC1B in colorectal cells Research Paper

HIC1 (Hypermethylated in Cancer 1) modulates the contractile activity of prostate stromal fibroblasts and directly regulates CXCL12 expression Research Paper

Anti-tumor activities of the new oral pan-RAF inhibitor, TAK-580, used as monotherapy or in combination with novel agents in multiple myeloma Research Paper

KDM5A and PHF2 positively control expression of pro-metastatic genes repressed by EWS/Fli1, and promote growth and metastatic properties in Ewing sarcoma Research Paper

Targeted lymphodepletion with a CD45-directed antibody radioconjugate as a novel conditioning regimen prior to adoptive cell therapy Research Paper

Altered lung tissue lipidomic profile in caspase-4 positive non-small cell lung cancer (NSCLC) patients Research Paper

ATM inhibition overcomes resistance to histone deacetylase inhibitor due to p21 induction and cell cycle arrest Research Paper

Preclinical evaluation of the anti-tumor activity of pralatrexate in high-risk neuroblastoma cells Research Paper

Panaxynol, a bioactive component of American ginseng, targets macrophages and suppresses colitis in mice Priority Research Paper

Clinical implications of chromatin accessibility in human cancers Research Paper

Synergistic combinations of paclitaxel and withaferin A against human non-small cell lung cancer cells Research Paper

Investigation of the role of VHL-HIF signaling in DNA repair and apoptosis in zebrafish Research Paper

hPCL3S promotes proliferation and migration of androgen-independent prostate cancer cells Research Paper

Acute promyelocytic leukemia (APL): a review of the literature Review

Mifamurtide and TAM-like macrophages: effect on proliferation, migration and differentiation of osteosarcoma cells Research Paper

Tumor suppressor genes and allele-specific expression: mechanisms and significance Research Paper

Cetuximab is efficient and safe in patients with advanced cutaneous squamous cell carcinoma: a retrospective, multicentre study Research Paper

Circulating tumor DNA analysis in the era of precision oncology Review

A squalamine derivative, NV669, as a novel PTP1B inhibitor: in vitro and in vivo effects on pancreatic and hepatic tumor growth Research Paper

Correction: FGFR1β is a driver isoform of FGFR1 alternative splicing in breast cancer cells Correction