The Oncosearch | Oncotarget

The noradrenergic profile of plasma metanephrine in neuroblastoma patients is reproduced in xenograft mice models and arise from PNMT downregulation Research Paper

Karim Abid, Maja Beck Popovic, Katia Balmas Bourloud, Jacqueline Schoumans, Joana Grand-Guillaume, Eric Grouzmann, Annick Mühlethaler-Mottet

Published Dec 23, 2020 · Vol. 12, No. 1 · pp. 49-60

Keywords: neuroblastoma, metanephrine, patient-derived xenograft, mouse model, Phenylethanolamine N-Methyltransferase

Terminally sialylated and fucosylated complex N-glycans are involved in the malignant behavior of high-grade glioma Research Paper

Hector A. Cuello, Gretel M. Ferreira, Cynthia A. Gulino, Alejandro Gomez Toledo, Valeria I. Segatori, Mariano R. Gabri

Published Dec 16, 2020 · Vol. 11, No. 52 · pp. 4822-4835

Keywords: glioma, glioblastoma, Lewis glycans, histone acetylation, N-glycans

Inhibitors of cytoskeletal dynamics in malignant mesothelioma Research Paper

Katarina Reis, Jack L. Arbiser, Anders Hjerpe, Katalin Dobra, Pontus Aspenström

Published Dec 4, 2020 · Vol. 11, No. 50 · pp. 4637-4647

Keywords: malignant mesothelioma, actin dynamics, vimentin, cytoskeleton, imipramine blue

Amalgamation of PI3K and EZH2 blockade synergistically regulates invasion and angiogenesis: combination therapy for glioblastoma multiforme Research Paper

Vishnu S. Mishra, Naveen Kumar, Masoom Raza, Seema Sehrawat

Published Dec 2, 2020 · Vol. 11, No. 51 · pp. 4754-4769

Keywords: precision neuroOncology, combination therapy, glioblastoma multiforme, pharmacological intervention, cytokine based proteomics

Alphastatin-C a new inhibitor of endothelial cell activation is a pro-arteriogenic agent in vivo and retards B16-F10 melanoma growth in a preclinical model Research Paper

Adilson Kleber Ferreira, Brunella Cristofaro, Milene Cristina Menezes, Ana Karina de Oliveira, Alexandre Keiji Tashima, Robson Lopes de Melo, Cristiane Castilho Fernandes Silva, Miryam Guillermina Palomino Rodriguez, Daniela Cajado de Oliveira Souza Carvalho, Ricardo Alexandre de Azevedo, Paulo Luiz de Sá Junior, Lisley Inata Mambelli, Fernanda Vieira Portaro, Luc Pardanaud, Anne Eichmann, Osvaldo Augusto Sant’Anna, Mxarcella Faria

Published Nov 30, 2020 · Vol. 11, No. 51 · pp. 4770-4787

Keywords: alphastatin-C, angiogenesis, peptides, melanoma, angiostatic

Novel 3-(3, 5-difluoro-4-hydroxyphenyl)-1-(naphthalen-2-yl) prop-2-en-1-one as a potent inhibitor of MAP-kinase in HeLa cell lines and anti-angiogenic activity is mediated by HIF-1α in EAC animal model Research Paper

Dileep Kumar M. Guruswamy, Kyathegowdana Doddi Srivinavasa Balaji, Kattepura Krishnappa Dharmappa, Shankar Jayarama

Published Nov 27, 2020 · Vol. 11, No. 50 · pp. 4661-4676

Keywords: novel chalcone, Bcl2, caspase 3, BAX, receptor tyrosine kinase inhibitor

Chemotherapy sensitivity testing on ovarian cancer cells isolated from malignant ascites Research Paper

Judith E. den Ouden, Guido J.R. Zaman, Jelle Dylus, Antoon M. van Doornmalen, Winfried R. Mulder, Yvonne Grobben, Wilhelmina E. van Riel, Joanne A. de Hullu, Rogier C. Buijsman, Anne M. van Altena

Published Nov 20, 2020 · Vol. 11, No. 49 · pp. 4570-4581

Keywords: ovarian cancer, chemotherapy sensitivity, prediction, ascites, proliferation assays

Identification of Mubritinib (TAK 165) as an inhibitor of KSHV driven primary effusion lymphoma via disruption of mitochondrial OXPHOS metabolism Research Paper

Abram Calderon, Samantha S. Soldan, Alessandra De Leo, Zhong Deng, Drew M. Frase, Emma M. Anderson, Yue Zhang, Olga Vladimirova, Fang Lu, Jessica C. Leung, Maureen E. Murphy, Paul M. Lieberman

Published Nov 7, 2020 · Vol. 11, No. 46 · pp. 4224-4242

Keywords: KSHV, LANA, high-throughput screen (HTS), primary effusion lymphoma, Mubritinib

Auto-antibodies against apolipoprotein A-1 block cancer cells proliferation and induce apoptosis Research Paper

Nathalie Satta, Rémy Weppe, Sabrina Pagano, Miguel Frias, Catherine Juillard, Nicolas Vuilleumier

Published Nov 7, 2020 · Vol. 11, No. 46 · pp. 4266-4280

Keywords: anti-apoA-1 antibodies, apoptose, cell proliferation, oxidative stress

CPEB1 orchestrates a fine-tuning of miR-145-5p tumor-suppressive activity on TWIST1 translation in prostate cancer cells Research Paper

Fatemeh Rajabi, Win-Yan Liu-Bordes, Marina Pinskaya, Foretek Dominika, Gueorgui Kratassiouk, Guillaume Pinna, Simona Nanni, Antonella Farsetti, Christian Gespach, Arturo Londoño-Vallejo, Irina Groisman

Published Nov 4, 2020 · Vol. 11, No. 45 · pp. 4155-4168

Keywords: miR-145-5p, TWIST1, CPEB1, EMT, prostate cancer

MEK inhibitors reduce cellular expression of ACE2, pERK, pRb while stimulating NK-mediated cytotoxicity and attenuating inflammatory cytokines relevant to SARS-CoV-2 infection Priority Research Paper

Lanlan Zhou, Kelsey Huntington, Shengliang Zhang, Lindsey Carlsen, Eui-Young So, Cassandra Parker, Ilyas Sahin, Howard Safran, Suchitra Kamle, Chang-Min Lee, Chun Geun Lee, Jack A. Elias, Kerry S. Campbell, Mandar T. Naik, Walter J. Atwood, Emile Youssef, Jonathan A. Pachter, Arunasalam Navaraj, Attila A. Seyhan, Olin Liang, Wafik S. El-Deiry

Published Oct 28, 2020 · Vol. 11, No. 46 · pp. 4201-4223

Keywords: ACE2, TMPRSS2, SARS-CoV-2, COVID-19, pseudovirus

MEK inhibitors reduce cellular expression of ACE2, pERK, pRb while stimulating NK-mediated cytotoxicity and attenuating inflammatory cytokines relevant to SARS-CoV-2 infection Priority Research Paper

Lanlan Zhou, Kelsey Huntington, Shengliang Zhang, Lindsey Carlsen, Eui-Young So, Cassandra Parker, Ilyas Sahin, Howard Safran, Suchitra Kamle, Chang-Min Lee, Chun Geun Lee, Jack A. Elias, Kerry S. Campbell, Mandar T. Naik, Walter J. Atwood, Emile Youssef, Jonathan A. Pachter, Arunasalam Navaraj, Attila A. Seyhan, Olin Liang, Wafik S. El-Deiry

Published Oct 28, 2020

Keywords: ACE2, TMPRSS2, SARS-CoV-2, COVID-19, pseudovirus

HIC1 (Hypermethylated in Cancer 1) modulates the contractile activity of prostate stromal fibroblasts and directly regulates CXCL12 expression Research Paper

Marion Dubuissez, Sonia Paget, Souhila Abdelfettah, Nathalie Spruyt, Vanessa Dehennaut, Gaylor Boulay, Ingrid Loison, Clementine de Schutter, Brian R. Rood, Martine Duterque-Coquillaud, Xavier Leroy, Dominique Leprince

Published Oct 21, 2020 · Vol. 11, No. 45 · pp. 4138-4154

Keywords: HIC1, CXCL12, SDF1, α-SMA, Acta2

Polymerized human hemoglobin increases the effectiveness of cisplatin-based chemotherapy in non-small cell lung cancer Research Paper

Alfredo Lucas, Donald A. Belcher, Carlos Munoz, Alexander T. Williams, Andre F. Palmer, Pedro Cabrales

Published Oct 7, 2020 · Vol. 11, No. 42 · pp. 3770-3781

Keywords: chemotherapy, cisplatin, polymerized hemoglobin, non-small cell lung cancer, hypoxia

Anti-tumor activities of the new oral pan-RAF inhibitor, TAK-580, used as monotherapy or in combination with novel agents in multiple myeloma Research Paper

Rikio Suzuki, Yuka Kitamura, Yoshihiko Nakamura, Hibiki Akashi, Yoshiaki Ogawa, Hiroshi Kawada, Kiyoshi Ando

Published Oct 7, 2020 · Vol. 11, No. 44 · pp. 3984-3997

Keywords: pan-RAF inhibitor, Bim, FOXO3a, bortezomib, lenalidomide

Predictive biomarkers for sacituzumab govitecan efficacy in Trop-2-expressing triple-negative breast cancer Research Paper

Thomas M. Cardillo, Diane L. Rossi, Maria B. Zalath, Donglin Liu, Roberto Arrojo, Robert M. Sharkey, Chien-Hsing Chang, David M. Goldenberg

Published Oct 1, 2020 · Vol. 11, No. 43 · pp. 3849-3862

Keywords: sacituzumab govitecan, Trop-2, biomarker, RAD51, triple-negative breast cancer

Evaluation of cancer-derived myocardial impairments using a mouse model Research Paper

Yoshihiro Miyagawa, Shota Nukaga, Takuya Mori, Rina Fujiwara-Tani, Kiyomu Fujii, Shiori Mori, Kei Goto, Shingo Kishi, Takamitsu Sasaki, Chie Nakashima, Hitoshi Ohmori, Isao Kawahara, Yi Luo, Hiroki Kuniyasu

Published Sep 20, 2020 · Vol. 11, No. 41 · pp. 3712-3722

Keywords: cachexia, myocardium, atrophy, mitochondria, oxidative stress

Correction: MiR-21 mediates sorafenib resistance of hepatocellular carcinoma cells by inhibiting autophagy via the PTEN/Akt pathway Correction

Changjun He, Xuesong Dong, Bo Zhai, Xian Jiang, Deli Dong, Baoxin Li, Hongchi Jiang, Shidong Xu, Xueying Sun

Published Sep 10, 2020

Simvastatin is a potential candidate drug in ovarian clear cell carcinomas Research Paper

Nicolai Skovbjerg Arildsen, Ingrid Hedenfalk

Published Sep 8, 2020 · Vol. 11, No. 40 · pp. 3660-3674

Keywords: ovarian clear cell cancer, simvastatin, CID-1067700, Rho GTPase, actin

AKT isoforms have discrete expression in triple negative breast cancers and roles in cisplatin sensitivity Research Paper

Bhumika Wadhwa, Masroor Paddar, Sameer Khan, Sameer Mir, Philip A.Clarke, Anna M. Grabowska, Devanahalli G. Vijay, Fayaz Malik

Published Sep 8, 2020 · Vol. 11, No. 45 · pp. 4178-4194

Keywords: AKT isoform, CSCs, ABCG2, drug resistance, TNBCs

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The noradrenergic profile of plasma metanephrine in neuroblastoma patients is reproduced in xenograft mice models and arise from PNMT downregulation Research Paper

Terminally sialylated and fucosylated complex N-glycans are involved in the malignant behavior of high-grade glioma Research Paper

Inhibitors of cytoskeletal dynamics in malignant mesothelioma Research Paper

Amalgamation of PI3K and EZH2 blockade synergistically regulates invasion and angiogenesis: combination therapy for glioblastoma multiforme Research Paper

Alphastatin-C a new inhibitor of endothelial cell activation is a pro-arteriogenic agent in vivo and retards B16-F10 melanoma growth in a preclinical model Research Paper

Novel 3-(3, 5-difluoro-4-hydroxyphenyl)-1-(naphthalen-2-yl) prop-2-en-1-one as a potent inhibitor of MAP-kinase in HeLa cell lines and anti-angiogenic activity is mediated by HIF-1α in EAC animal model Research Paper

Chemotherapy sensitivity testing on ovarian cancer cells isolated from malignant ascites Research Paper

Identification of Mubritinib (TAK 165) as an inhibitor of KSHV driven primary effusion lymphoma via disruption of mitochondrial OXPHOS metabolism Research Paper

Auto-antibodies against apolipoprotein A-1 block cancer cells proliferation and induce apoptosis Research Paper

CPEB1 orchestrates a fine-tuning of miR-145-5p tumor-suppressive activity on TWIST1 translation in prostate cancer cells Research Paper

MEK inhibitors reduce cellular expression of ACE2, pERK, pRb while stimulating NK-mediated cytotoxicity and attenuating inflammatory cytokines relevant to SARS-CoV-2 infection Priority Research Paper

MEK inhibitors reduce cellular expression of ACE2, pERK, pRb while stimulating NK-mediated cytotoxicity and attenuating inflammatory cytokines relevant to SARS-CoV-2 infection Priority Research Paper

HIC1 (Hypermethylated in Cancer 1) modulates the contractile activity of prostate stromal fibroblasts and directly regulates CXCL12 expression Research Paper

Polymerized human hemoglobin increases the effectiveness of cisplatin-based chemotherapy in non-small cell lung cancer Research Paper

Anti-tumor activities of the new oral pan-RAF inhibitor, TAK-580, used as monotherapy or in combination with novel agents in multiple myeloma Research Paper

Predictive biomarkers for sacituzumab govitecan efficacy in Trop-2-expressing triple-negative breast cancer Research Paper

Evaluation of cancer-derived myocardial impairments using a mouse model Research Paper

Correction: MiR-21 mediates sorafenib resistance of hepatocellular carcinoma cells by inhibiting autophagy via the PTEN/Akt pathway Correction

Simvastatin is a potential candidate drug in ovarian clear cell carcinomas Research Paper

AKT isoforms have discrete expression in triple negative breast cancers and roles in cisplatin sensitivity Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

The noradrenergic profile of plasma metanephrine in neuroblastoma patients is reproduced in xenograft mice models and arise from PNMT downregulation Research Paper

Terminally sialylated and fucosylated complex N-glycans are involved in the malignant behavior of high-grade glioma Research Paper

Inhibitors of cytoskeletal dynamics in malignant mesothelioma Research Paper

Amalgamation of PI3K and EZH2 blockade synergistically regulates invasion and angiogenesis: combination therapy for glioblastoma multiforme Research Paper

Alphastatin-C a new inhibitor of endothelial cell activation is a pro-arteriogenic agent in vivo and retards B16-F10 melanoma growth in a preclinical model Research Paper

Novel 3-(3, 5-difluoro-4-hydroxyphenyl)-1-(naphthalen-2-yl) prop-2-en-1-one as a potent inhibitor of MAP-kinase in HeLa cell lines and anti-angiogenic activity is mediated by HIF-1α in EAC animal model Research Paper

Chemotherapy sensitivity testing on ovarian cancer cells isolated from malignant ascites Research Paper

Identification of Mubritinib (TAK 165) as an inhibitor of KSHV driven primary effusion lymphoma via disruption of mitochondrial OXPHOS metabolism Research Paper

Auto-antibodies against apolipoprotein A-1 block cancer cells proliferation and induce apoptosis Research Paper

CPEB1 orchestrates a fine-tuning of miR-145-5p tumor-suppressive activity on TWIST1 translation in prostate cancer cells Research Paper

MEK inhibitors reduce cellular expression of ACE2, pERK, pRb while stimulating NK-mediated cytotoxicity and attenuating inflammatory cytokines relevant to SARS-CoV-2 infection Priority Research Paper

MEK inhibitors reduce cellular expression of ACE2, pERK, pRb while stimulating NK-mediated cytotoxicity and attenuating inflammatory cytokines relevant to SARS-CoV-2 infection Priority Research Paper

HIC1 (Hypermethylated in Cancer 1) modulates the contractile activity of prostate stromal fibroblasts and directly regulates CXCL12 expression Research Paper

Polymerized human hemoglobin increases the effectiveness of cisplatin-based chemotherapy in non-small cell lung cancer Research Paper

Anti-tumor activities of the new oral pan-RAF inhibitor, TAK-580, used as monotherapy or in combination with novel agents in multiple myeloma Research Paper

Predictive biomarkers for sacituzumab govitecan efficacy in Trop-2-expressing triple-negative breast cancer Research Paper

Evaluation of cancer-derived myocardial impairments using a mouse model Research Paper

Correction: MiR-21 mediates sorafenib resistance of hepatocellular carcinoma cells by inhibiting autophagy via the PTEN/Akt pathway Correction

Simvastatin is a potential candidate drug in ovarian clear cell carcinomas Research Paper

AKT isoforms have discrete expression in triple negative breast cancers and roles in cisplatin sensitivity Research Paper