The Oncosearch | Oncotarget

Multipeptide stimulated PBMCs generate T_EM/T_CM for adoptive cell therapy in multiple myeloma Research Paper

Trupti Vardam-Kaur, Latha B. Pathangey, Daniel J. McCormick, P. Leif Bergsagel, Peter A. Cohen, Sandra J. Gendler

Published Aug 27, 2021 · Vol. 12, No. 20 · pp. 2051-2067

Keywords: multiple myeloma, cellular therapy, CD4/CD8 T cells, peptides, immunotherapy

Normal tissue and tumor microenvironment adaptations to aerobic exercise enhance doxorubicin anti-tumor efficacy and ameliorate its cardiotoxicity in retired breeder mice Priority Research Paper

Zachary R. Wakefield, Mai Tanaka, Christine Pampo, Sharon Lepler, Lori Rice, Joy Guingab-Cagmat, Timothy J. Garrett, Dietmar W. Siemann

Published Aug 18, 2021 · Vol. 12, No. 18 · pp. 1737-1748

Keywords: aerobic exercise, breast cancer, hypoxia, doxorubicin, cardiotoxicity

Pim kinase inhibitor co-treatment decreases alternative non-homologous end-joining DNA repair and genomic instability induced by topoisomerase 2 inhibitors in cells with FLT3 internal tandem duplication Research Paper

Mario Scarpa, Shivani Kapoor, Eric S. Tvedte, Kshama A. Doshi, Ying S. Zou, Prerna Singh, Jonelle K. Lee, Aditi Chatterjee, Moaath K. Mustafa Ali, Robin E. Bromley, Julie C. Dunning Hotopp, Feyruz V. Rassool, Maria R. Baer

Published Aug 2, 2021 · Vol. 12, No. 18 · pp. 1763-1779

Keywords: FLT3 internal tandem duplication, Pim kinase, alternative non-homologous end-joining DNA repair, genomic instability, topoisomerase 2 inhibitors

MiR-7-5p inhibits thyroid cell proliferation by targeting the EGFR/MAPK and IRS2/PI3K signaling pathways Research Paper

Alice Augenlicht, Manuel Saiselet, Myriam Decaussin-Petrucci, Guy Andry, Jacques E. Dumont, Carine Maenhaut

Published Jul 17, 2021 · Vol. 12, No. 16 · pp. 1587-1599

Keywords: miRNA, papillary thyroid carcinoma, IRS2, MAPK, PI3K

Correction: Oncogenic RAS-induced senescence in human primary thyrocytes: molecular effectors and inflammatory secretome involved Correction

Maria Grazia Vizioli, Joana Santos, Silvana Pilotti, Mara Mazzoni, Maria Chiara Anania, Claudia Miranda, Sonia Pagliardini, Marco A. Pierotti, Jesus Gil, Angela Greco

Published Jul 2, 2021 · Vol. 13, No. 1 · pp. 1120-1121

Next-generation multimodality of nutrigenomic cancer therapy: sulforaphane in combination with acetazolamide actively target bronchial carcinoid cancer in disabling the PI3K/Akt/mTOR survival pathway and inducing apoptosis Research Paper

Reza Bayat Mokhtari, Bessi Qorri, Narges Baluch, Angelo Sparaneo, Federico Pio Fabrizio, Lucia Anna Muscarella, Albina Tyker, Sushil Kumar, Hai-Ling Margaret Cheng, Myron R. Szewczuk, Bikul Das, Herman Yeger

Published Jun 22, 2021 · Vol. 12, No. 15 · pp. 1470-1489

Keywords: sulforaphane, acetazolamide, bronchial carcinoid tumors, serotonin, carbonic anhydrase

Eltrombopag and its iron chelating properties in pediatric acute myeloid leukemia Research Paper

Maura Argenziano, Chiara Tortora, Alessandra Di Paola, Elvira Pota, Martina Di Martino, Daniela Di Pinto, Caterina Di Leva, Francesca Rossi

Published Jun 16, 2021 · Vol. 12, No. 14 · pp. 1377-1387

Keywords: acute monocytic leukemia, eltrombopag, deferasirox, iron chelation, cancer

Frame-shift mediated reduction of gain-of-function p53 R273H and deletion of the R273H C-terminus in breast cancer cells result in replication-stress sensitivity Priority Research Paper

Viola Ellison, George K. Annor, Clara Freedman, Gu Xiao, Devon Lundine, Elzbieta Freulich, Carol Prives, Jill Bargonetti

Published May 20, 2021 · Vol. 12, No. 12 · pp. 1128-1146

Keywords: mutant p53, gain-of-function, oligomerization, DNA replication, frame-shift

Epigallocatechin-3-gallate modulates Tau Post-translational modifications and cytoskeletal network Research Paper

Shweta Kishor Sonawane, Subashchandrabose Chinnathambi

Published May 7, 2021 · Vol. 12, No. 11 · pp. 1083-1099

Keywords: Alzheimer’s disease, Tau protein, Tau PTMs, Tau glycation, Tau glycation inhibition

A novel E2F1-regulated lncRNA, LAPAS1, is required for S phase progression and cell proliferation Research Paper

Esther Baruch, Tali Nizri-Megnaji, Oron Berkowitz, Doron Ginsberg

Published May 7, 2021 · Vol. 12, No. 11 · pp. 1072-1082

Keywords: lncRNA, E2F, cell cycle, cell proliferation

Loss of CPAP causes sustained EGFR signaling and epithelial-mesenchymal transition in oral cancer Research Paper

Radhika R. Gudi, Harinarayanan Janakiraman, Philip H. Howe, Viswanathan Palanisamy, Chenthamarakshan Vasu

Published Mar 27, 2021 · Vol. 12, No. 8 · pp. 807-822

Keywords: tumorigenesis, epithelial-mesenchymal transition, oral squamous cell carcinoma, EGFR, CPAP

Decreased expression of the translation factor eIF3e induces senescence in breast cancer cells via suppression of PARP1 and activation of mTORC1 Research Paper

Christelle Morris, Sébastien Durand, Pierre Jalinot

Published Mar 13, 2021 · Vol. 12, No. 7 · pp. 649-664

Keywords: breast cancer, senescence-associated secretory phenotype, eIF3, PARP1, mTORC1

Inhibition of resistant triple-negative breast cancer cells with low-dose 6-mercaptopurine and 5-azacitidine Research Paper

Balraj Singh, Vanessa N. Sarli, Anthony Lucci

Published Mar 12, 2021 · Vol. 12, No. 7 · pp. 626-637

Keywords: resistant TNBC, minimal residual disease, intratumor heterogeneity, breast cancer relapse, metastasis prevention

The cancer testis antigens CABYR-a/b and CABYR-c are expressed in a subset of colorectal cancers and hold promise as targets for specific immunotherapy Research Paper

H.M.C. Shantha Kumara, Elie Sutton, Otavia L. Caballero, Tao Su, Xiaohong Yan, Aqeel Ahmed, Sonali A.C. Herath, Vesna Cekic, Linda Njoh, Daniel D. Kirchoff, Richard L. Whelan

Published Feb 9, 2021 · Vol. 12, No. 5 · pp. 412-421

Keywords: cancer testis antigens, colorectal cancer, CABYR a/b, c

Correction: Cbl-b inhibits P-gp transporter function by preventing its translocation into caveolae in multiple drug-resistant gastric and breast cancers Correction

Ye Zhang, Xiujuan Qu, Yuee Teng, Zhi Li, Ling Xu, Jing Liu, Yanju Ma, Yibo Fan, Ce Li, Shizhou Liu, Zhenning Wang, Xuejun Hu, Jingdong Zhang, Yunpeng Liu

Published Jan 30, 2021 · Vol. 12, No. 16 · pp. 1634-1637

STAT3 induces the expression of GLI1 in chronic lymphocytic leukemia cells Research Paper

Uri Rozovski, David M. Harris, Ping Li, Zhiming Liu, Preetesh Jain, Taghi Manshouri, Ivo Veletic, Alessandra Ferrajoli, Prithviraj Bose, Phillip Thompson, Nitin Jain, Srdan Verstovsek, William Wierda, Michael J. Keating, Zeev Estrov

Published Jan 30, 2021 · Vol. 12, No. 5 · pp. 401-411

Keywords: CLL, STAT3, GLI1, apoptosis, transcription

Krüppel-like factor 4 promotes survival and expansion in acute myeloid leukemia cells Research Paper

Andrew Henry Lewis, Cory Seth Bridges, Viraaj Singh Punia, Abraham Fausto Jornada Cooper, Monica Puppi, H. Daniel Lacorazza

Published Jan 25, 2021 · Vol. 12, No. 4 · pp. 255-267

Keywords: acute myeloid leukemia, KLF4, cancer, gene editing, cell growth

Oncolytic virotherapy with SOCS3 enhances viral replicative potency and oncolysis for gastric cancer Research Paper

Shuichi Matsumura, Mikihito Nakamori, Toshiaki Tsuji, Tomoya Kato, Masaki Nakamura, Toshiyasu Ojima, Hiroshi Fukuhara, Yasushi Ino, Tomoki Todo, Hiroki Yamaue

Published Jan 22, 2021 · Vol. 12, No. 4 · pp. 344-354

Keywords: oncolytic virus, herpes simplex virus, gastric cancer

Downregulation of SOX2 by inhibition of Usp9X induces apoptosis in melanoma Research Paper

Harish Potu, Malathi Kandarpa, Luke F. Peterson, Alison Durham, Nicholas J. Donato, Moshe Talpaz

Published Jan 12, 2021 · Vol. 12, No. 3 · pp. 160-172

Keywords: melanoma, deubiquitinase (DUB) enzyme, transcription factors, USP9X, DUB inhibitor

Characterization of FGFR signaling in prostate cancer stem cells and inhibition via TKI treatment Research Paper

Juyeon Ko, April N. Meyer, Martin Haas, Daniel J. Donoghue

Published Dec 23, 2020 · Vol. 12, No. 1 · pp. 22-36

Keywords: metastatic castrate-resistant prostate cancer, spheroid culture, tyrosine kinase inhibitor

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Multipeptide stimulated PBMCs generate T_EM/T_CM for adoptive cell therapy in multiple myeloma Research Paper

Normal tissue and tumor microenvironment adaptations to aerobic exercise enhance doxorubicin anti-tumor efficacy and ameliorate its cardiotoxicity in retired breeder mice Priority Research Paper

Pim kinase inhibitor co-treatment decreases alternative non-homologous end-joining DNA repair and genomic instability induced by topoisomerase 2 inhibitors in cells with FLT3 internal tandem duplication Research Paper

MiR-7-5p inhibits thyroid cell proliferation by targeting the EGFR/MAPK and IRS2/PI3K signaling pathways Research Paper

Correction: Oncogenic RAS-induced senescence in human primary thyrocytes: molecular effectors and inflammatory secretome involved Correction

Next-generation multimodality of nutrigenomic cancer therapy: sulforaphane in combination with acetazolamide actively target bronchial carcinoid cancer in disabling the PI3K/Akt/mTOR survival pathway and inducing apoptosis Research Paper

Eltrombopag and its iron chelating properties in pediatric acute myeloid leukemia Research Paper

Frame-shift mediated reduction of gain-of-function p53 R273H and deletion of the R273H C-terminus in breast cancer cells result in replication-stress sensitivity Priority Research Paper

Epigallocatechin-3-gallate modulates Tau Post-translational modifications and cytoskeletal network Research Paper

A novel E2F1-regulated lncRNA, LAPAS1, is required for S phase progression and cell proliferation Research Paper

Loss of CPAP causes sustained EGFR signaling and epithelial-mesenchymal transition in oral cancer Research Paper

Decreased expression of the translation factor eIF3e induces senescence in breast cancer cells via suppression of PARP1 and activation of mTORC1 Research Paper

Inhibition of resistant triple-negative breast cancer cells with low-dose 6-mercaptopurine and 5-azacitidine Research Paper

The cancer testis antigens CABYR-a/b and CABYR-c are expressed in a subset of colorectal cancers and hold promise as targets for specific immunotherapy Research Paper

Correction: Cbl-b inhibits P-gp transporter function by preventing its translocation into caveolae in multiple drug-resistant gastric and breast cancers Correction

STAT3 induces the expression of GLI1 in chronic lymphocytic leukemia cells Research Paper

Krüppel-like factor 4 promotes survival and expansion in acute myeloid leukemia cells Research Paper

Oncolytic virotherapy with SOCS3 enhances viral replicative potency and oncolysis for gastric cancer Research Paper

Downregulation of SOX2 by inhibition of Usp9X induces apoptosis in melanoma Research Paper

Characterization of FGFR signaling in prostate cancer stem cells and inhibition via TKI treatment Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

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Multipeptide stimulated PBMCs generate TEM/TCM for adoptive cell therapy in multiple myeloma Research Paper

Normal tissue and tumor microenvironment adaptations to aerobic exercise enhance doxorubicin anti-tumor efficacy and ameliorate its cardiotoxicity in retired breeder mice Priority Research Paper

Pim kinase inhibitor co-treatment decreases alternative non-homologous end-joining DNA repair and genomic instability induced by topoisomerase 2 inhibitors in cells with FLT3 internal tandem duplication Research Paper

MiR-7-5p inhibits thyroid cell proliferation by targeting the EGFR/MAPK and IRS2/PI3K signaling pathways Research Paper

Correction: Oncogenic RAS-induced senescence in human primary thyrocytes: molecular effectors and inflammatory secretome involved Correction

Next-generation multimodality of nutrigenomic cancer therapy: sulforaphane in combination with acetazolamide actively target bronchial carcinoid cancer in disabling the PI3K/Akt/mTOR survival pathway and inducing apoptosis Research Paper

Eltrombopag and its iron chelating properties in pediatric acute myeloid leukemia Research Paper

Frame-shift mediated reduction of gain-of-function p53 R273H and deletion of the R273H C-terminus in breast cancer cells result in replication-stress sensitivity Priority Research Paper

Epigallocatechin-3-gallate modulates Tau Post-translational modifications and cytoskeletal network Research Paper

A novel E2F1-regulated lncRNA, LAPAS1, is required for S phase progression and cell proliferation Research Paper

Loss of CPAP causes sustained EGFR signaling and epithelial-mesenchymal transition in oral cancer Research Paper

Decreased expression of the translation factor eIF3e induces senescence in breast cancer cells via suppression of PARP1 and activation of mTORC1 Research Paper

Inhibition of resistant triple-negative breast cancer cells with low-dose 6-mercaptopurine and 5-azacitidine Research Paper

The cancer testis antigens CABYR-a/b and CABYR-c are expressed in a subset of colorectal cancers and hold promise as targets for specific immunotherapy Research Paper

Correction: Cbl-b inhibits P-gp transporter function by preventing its translocation into caveolae in multiple drug-resistant gastric and breast cancers Correction

STAT3 induces the expression of GLI1 in chronic lymphocytic leukemia cells Research Paper

Krüppel-like factor 4 promotes survival and expansion in acute myeloid leukemia cells Research Paper

Oncolytic virotherapy with SOCS3 enhances viral replicative potency and oncolysis for gastric cancer Research Paper

Downregulation of SOX2 by inhibition of Usp9X induces apoptosis in melanoma Research Paper

Characterization of FGFR signaling in prostate cancer stem cells and inhibition via TKI treatment Research Paper

Multipeptide stimulated PBMCs generate T_EM/T_CM for adoptive cell therapy in multiple myeloma Research Paper