The Oncosearch | Oncotarget

Using drug scheduling to manage adverse events associated with hedgehog pathway inhibitors for basal cell carcinoma Review

John T. Lear, Reinhard Dummer, Alexander Guminski

Published Dec 1, 2021 · Vol. 12, No. 26 · pp. 2531-2540

Keywords: adverse events, basal cell carcinoma, sonidegib, hedgehog inhibitor, drug scheduling

The potential of PIVKA-II as a treatment response biomarker in hepatocellular carcinoma: a prospective United Kingdom cohort study Research Paper

Vandana M. Sagar, Kathyrn Herring, Stuart Curbishley, James Hodson, Peter Fletcher, Salil Karkhanis, Homoyon Mehrzad, Pankaj Punia, Tahir Shah, Shishir Shetty, Yuk Ting Ma

Published Nov 16, 2021 · Vol. 12, No. 24 · pp. 2338-2350

Keywords: hepatocellular carcinoma, biomarker, PIVKA-II

Circulating low density neutrophils of breast cancer patients are associated with their worse prognosis due to the impairment of T cell responses Research Paper

Diana P. Saraiva, Bruna F. Correia, Rute Salvador, Nídia de Sousa, António Jacinto, Sofia Braga, M. Guadalupe Cabral

Published Nov 15, 2021 · Vol. 12, No. 24 · pp. 2388-2403

Keywords: breast cancer, chemotherapy response, tumor-associated neutrophils, low density neutrophils, biomarker

Caloric restriction causes a distinct reorganization of the lipidome in quiescent and non-quiescent cells of budding yeast Research Paper

Karamat Mohammad, Emmanuel Orfanos, Vladimir I. Titorenko

Published Nov 13, 2021 · Vol. 12, No. 24 · pp. 2351-2374

Keywords: cellular aging, cellular quiescence, caloric restriction, geroprotectors, lipids

Molecular characterization of Kita-Kyushu lung cancer antigen (KK-LC-1) expressing carcinomas Research Paper

Robert Hsu, Yasmine Baca, Joanne Xiu, Rongfu Wang, J. Nicholas Bodor, Chul Kim, Hina Khan, Hirva Mamdani, Misako Nagasaka, Sonam Puri, Stephen V. Liu, W. Michael Korn, Jorge J. Nieva

Published Nov 13, 2021 · Vol. 12, No. 25 · pp. 2449-2458

Keywords: lung cancer, tumor microenvironment, diagnostic biomarkers, biomarkers for immunotherapy, cancer testis antigen

Correction: Pre-clinical validation of B cell maturation antigen (BCMA) as a target for T cell immunotherapy of multiple myeloma Correction

De-Xiu Bu, Reshma Singh, Eugene E. Choi, Marco Ruella, Selene Nunez-Cruz, Keith G. Mansfield, Paul Bennett, Nathanial Barton, Qilong Wu, Jiquan Zhang, Yongqiang Wang, Lai Wei, Shawn Cogan, Tucker Ezell, Shree Joshi, Kellie J. Latimer, Brian Granda, William R. Tschantz, Regina M. Young, Heather A. Huet, Celeste J. Richardson, Michael C. Milone

Published Nov 2, 2021

Correction: PKM2 promotes metastasis by recruiting myeloid-derived suppressor cells and indicates poor prognosis for hepatocellular carcinoma Correction

Wei-Ren Liu, Meng-Xin Tian, Liu-Xiao Yang, Yu-Li Lin, Lei Jin, Zhen-Bin Ding, Ying-Hao Shen, Yuan-Fei Peng, Dong-Mei Gao, Jian Zhou, Shuang-Jian Qiu, Zhi Dai, Rui He, Jia Fan, Ying-Hong Shi

Published Oct 28, 2021

Correction: Melanoma cell therapy: Endothelial progenitor cells as shuttle of the MMP12 uPAR-degrading enzyme Correction

Anna Laurenzana, Alessio Biagioni, Silvia D’Alessio, Francesca Bianchini, Anastasia Chillà, Francesca Margheri, Cristina Luciani, Benedetta Mazzanti, Nicola Pimpinelli, Eugenio Torre, Silvio Danese, Lido Calorini, Mario Del Rosso, Gabriella Fibbi

Published Oct 28, 2021

The “Immunoscore” in rectal cancer: could we search quality beyond quantity of life? Research Perspective

Amos Kirilovsky, Carine El Sissy, Guy Zeitoun, Florence Marliot, Nacilla Haicheur, Christine Lagorce-Pagès, Julien Taieb, Mehdi Karoui, Petra Custers, Edina Dizdarevic, Soledad Iseas, Torben Frøstrup Hansen, Lars Henrik Jensen, Geerard Beets, Jean Pierre Gérard, Mireia Castillo-Martin, Nuno Figueiredo, Angelita Habr-Gama, Rodrigo Perez, Jérôme Galon, Franck Pagès

Published Oct 16, 2021 · Vol. 13, No. 1 · pp. 18-31

Keywords: rectal cancer, immunoscore, watch and wait, prognosis, radiochemotherapy

ATR inhibition reverses the resistance of homologous recombination deficient MGMT^low/MMR^proficient cancer cells to temozolomide Priority Research Paper

Lara H. El Touny, Curtis Hose, John Connelly, Erik Harris, Anne Monks, Angie B. Dull, Deborah F. Wilsker, Melinda G. Hollingshead, Michelle Gottholm-Ahalt, Sergio Y. Alcoser, Michael E. Mullendore, Ralph E. Parchment, James H. Doroshow, Beverly A. Teicher, Annamaria Rapisarda

Published Sep 28, 2021 · Vol. 12, No. 21 · pp. 2114-2130

Keywords: TMZ, MMR, ATR, HR, REV3L

Hyperprogression of a mismatch repair-deficient colon cancer in a humanized mouse model following administration of immune checkpoint inhibitor pembrolizumab Research Paper

Ilyas Sahin, Andrew George, Shengliang Zhang, Kelsey E. Huntington, Zehra Ordulu, Lanlan Zhou, Wafik S. El-Deiry

Published Sep 24, 2021 · Vol. 12, No. 21 · pp. 2131-2146

Keywords: cancer immunotherapy, immune checkpoint inhibitors, hyperprogressive disease (HPD), hyperprogression (HP), humanized mouse

Loss of DRO1/CCDC80 in the tumor microenvironment promotes carcinogenesis Research Paper

Jessica I. Christian, Agnieszka Pastula, Andreas Herbst, Jens Neumann, Maximilian K. Marschall, Andrea Ofner, Heike Zierahn, Marlon R. Schneider, Eckhard Wolf, Michael Quante, Frank T. Kolligs

Published Sep 22, 2021 · Vol. 13, No. 1 · pp. 615-627

Keywords: DRO1, CCDC80, colorectal cancer, tumor microenvironment, tumor suppressor

P10s-PADRE vaccine combined with neoadjuvant chemotherapy in ER-positive breast cancer patients induces humoral and cellular immune responses Research Paper

Issam Makhoul, Saddam Mohammed Ibrahim, Muhammad Abu-Rmaileh, Fariba Jousheghany, Eric R. Siegel, Lora J. Rogers, John J. Lee, Sergio Pina-Oviedo, Ginell R. Post, J. Thaddeus Beck, Thomas Kieber-Emmons, Behjatolah Monzavi-Karbassi

Published Sep 16, 2021 · Vol. 12, No. 22 · pp. 2252-2265

Keywords: cancer vaccine, peptide mimotopes, combination therapy, breast cancer

Luminescence complementation technology for the identification of MYC:TRRAP inhibitors Research Paper

Edmond J. Feris, John W. Hinds, Michael D. Cole

Published Sep 11, 2021 · Vol. 12, No. 21 · pp. 2147-2157

Keywords: cancer, drug discovery, targeted therapy, oncogene, transcription factor

Comparative microsomal proteomics of a model lung cancer cell line NCI-H23 reveals distinct differences between molecular profiles of 3D and 2D cultured cells Research Paper

Jan A. Kaczmarczyk, Rhonda R. Roberts, Brian T. Luke, King C. Chan, Carly M. Van Wagoner, Robin A. Felder, Richard G. Saul, Colantonio Simona, Josip Blonder

Published Sep 3, 2021 · Vol. 12, No. 20 · pp. 2022-2038

Keywords: lung cancer, proteomics, 2D vs. 3D cultured cells, preclinical testing model, drug target discovery

Exploratory comparisons between different anti-mitotics in clinically-used drug combination in triple negative breast cancer Research Paper

Bruna Cândido Guido, Douglas Cardoso Brandão, Ana Luisa Augusto Barbosa, Monique Jacob Xavier Vianna, Lucas Faro, Luciana Machado Ramos, Fabíola Nihi, Márcio Botelho de Castro, Brenno A.D. Neto, José Raimundo Corrêa, Sônia Nair Báo

Published Aug 27, 2021 · Vol. 12, No. 19 · pp. 1920-1936

Keywords: KIF11 inhibition, Kinesin Eg5, breast cancer, adjuvant treatment, cancer progression

Multipeptide stimulated PBMCs generate T_EM/T_CM for adoptive cell therapy in multiple myeloma Research Paper

Trupti Vardam-Kaur, Latha B. Pathangey, Daniel J. McCormick, P. Leif Bergsagel, Peter A. Cohen, Sandra J. Gendler

Published Aug 27, 2021 · Vol. 12, No. 20 · pp. 2051-2067

Keywords: multiple myeloma, cellular therapy, CD4/CD8 T cells, peptides, immunotherapy

Trends in oligomannosylation and α1,2-mannosidase expression in human cancers Research Paper

Sayantani Chatterjee, Julian Ugonotti, Ling Y. Lee, Arun Everest-Dass, Rebeca Kawahara, Morten Thaysen-Andersen

Published Aug 24, 2021 · Vol. 12, No. 21 · pp. 2188-2205

Keywords: oligomannose, α1,2-mannosidase, cancer, glycomics, mass spectrometry

NEDD8-activating enzyme inhibition induces cell cycle arrest and anaphase catastrophe in malignant T-cells Research Paper

Adam S. Kittai, Olga V. Danilova, Vi Lam, Tingting Liu, Nur Bruss, Scott Best, Guang Fan, Alexey V. Danilov

Published Aug 23, 2021 · Vol. 12, No. 20 · pp. 2068-2074

Keywords: pevonedistat, T-cell lymphoma, chromosomal instability, anaphase catastrophe

Novel insights into the molecular mechanisms underlying risk of colorectal cancer from smoking and red/processed meat carcinogens by modeling exposure in normal colon organoids Research Paper

Matthew Devall, Christopher H. Dampier, Stephen Eaton, Mourad W. Ali, Virginia Díez-Obrero, Ferran Moratalla-Navarro, Jennifer Bryant, Lucas T. Jennelle, Victor Moreno, Steven M. Powell, Ulrike Peters, Graham Casey

Published Aug 18, 2021 · Vol. 12, No. 19 · pp. 1863-1877

Keywords: colon organoids, microsatellite instability, smoking, single-cell deconvolution, weighted gene co-expression network analysis

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Using drug scheduling to manage adverse events associated with hedgehog pathway inhibitors for basal cell carcinoma Review

The potential of PIVKA-II as a treatment response biomarker in hepatocellular carcinoma: a prospective United Kingdom cohort study Research Paper

Circulating low density neutrophils of breast cancer patients are associated with their worse prognosis due to the impairment of T cell responses Research Paper

Caloric restriction causes a distinct reorganization of the lipidome in quiescent and non-quiescent cells of budding yeast Research Paper

Molecular characterization of Kita-Kyushu lung cancer antigen (KK-LC-1) expressing carcinomas Research Paper

Correction: Pre-clinical validation of B cell maturation antigen (BCMA) as a target for T cell immunotherapy of multiple myeloma Correction

Correction: PKM2 promotes metastasis by recruiting myeloid-derived suppressor cells and indicates poor prognosis for hepatocellular carcinoma Correction

Correction: Melanoma cell therapy: Endothelial progenitor cells as shuttle of the MMP12 uPAR-degrading enzyme Correction

The “Immunoscore” in rectal cancer: could we search quality beyond quantity of life? Research Perspective

ATR inhibition reverses the resistance of homologous recombination deficient MGMT^low/MMR^proficient cancer cells to temozolomide Priority Research Paper

Hyperprogression of a mismatch repair-deficient colon cancer in a humanized mouse model following administration of immune checkpoint inhibitor pembrolizumab Research Paper

Loss of DRO1/CCDC80 in the tumor microenvironment promotes carcinogenesis Research Paper

P10s-PADRE vaccine combined with neoadjuvant chemotherapy in ER-positive breast cancer patients induces humoral and cellular immune responses Research Paper

Luminescence complementation technology for the identification of MYC:TRRAP inhibitors Research Paper

Comparative microsomal proteomics of a model lung cancer cell line NCI-H23 reveals distinct differences between molecular profiles of 3D and 2D cultured cells Research Paper

Exploratory comparisons between different anti-mitotics in clinically-used drug combination in triple negative breast cancer Research Paper

Multipeptide stimulated PBMCs generate T_EM/T_CM for adoptive cell therapy in multiple myeloma Research Paper

Trends in oligomannosylation and α1,2-mannosidase expression in human cancers Research Paper

NEDD8-activating enzyme inhibition induces cell cycle arrest and anaphase catastrophe in malignant T-cells Research Paper

Novel insights into the molecular mechanisms underlying risk of colorectal cancer from smoking and red/processed meat carcinogens by modeling exposure in normal colon organoids Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Using drug scheduling to manage adverse events associated with hedgehog pathway inhibitors for basal cell carcinoma Review

The potential of PIVKA-II as a treatment response biomarker in hepatocellular carcinoma: a prospective United Kingdom cohort study Research Paper

Circulating low density neutrophils of breast cancer patients are associated with their worse prognosis due to the impairment of T cell responses Research Paper

Caloric restriction causes a distinct reorganization of the lipidome in quiescent and non-quiescent cells of budding yeast Research Paper

Molecular characterization of Kita-Kyushu lung cancer antigen (KK-LC-1) expressing carcinomas Research Paper

Correction: Pre-clinical validation of B cell maturation antigen (BCMA) as a target for T cell immunotherapy of multiple myeloma Correction

Correction: PKM2 promotes metastasis by recruiting myeloid-derived suppressor cells and indicates poor prognosis for hepatocellular carcinoma Correction

Correction: Melanoma cell therapy: Endothelial progenitor cells as shuttle of the MMP12 uPAR-degrading enzyme Correction

The “Immunoscore” in rectal cancer: could we search quality beyond quantity of life? Research Perspective

ATR inhibition reverses the resistance of homologous recombination deficient MGMTlow/MMRproficient cancer cells to temozolomide Priority Research Paper

Hyperprogression of a mismatch repair-deficient colon cancer in a humanized mouse model following administration of immune checkpoint inhibitor pembrolizumab Research Paper

Loss of DRO1/CCDC80 in the tumor microenvironment promotes carcinogenesis Research Paper

P10s-PADRE vaccine combined with neoadjuvant chemotherapy in ER-positive breast cancer patients induces humoral and cellular immune responses Research Paper

Luminescence complementation technology for the identification of MYC:TRRAP inhibitors Research Paper

Comparative microsomal proteomics of a model lung cancer cell line NCI-H23 reveals distinct differences between molecular profiles of 3D and 2D cultured cells Research Paper

Exploratory comparisons between different anti-mitotics in clinically-used drug combination in triple negative breast cancer Research Paper

Multipeptide stimulated PBMCs generate TEM/TCM for adoptive cell therapy in multiple myeloma Research Paper

Trends in oligomannosylation and α1,2-mannosidase expression in human cancers Research Paper

NEDD8-activating enzyme inhibition induces cell cycle arrest and anaphase catastrophe in malignant T-cells Research Paper

Novel insights into the molecular mechanisms underlying risk of colorectal cancer from smoking and red/processed meat carcinogens by modeling exposure in normal colon organoids Research Paper

ATR inhibition reverses the resistance of homologous recombination deficient MGMT^low/MMR^proficient cancer cells to temozolomide Priority Research Paper

Multipeptide stimulated PBMCs generate T_EM/T_CM for adoptive cell therapy in multiple myeloma Research Paper