The Oncosearch | Oncotarget

The macrophage migration inhibitory factor (MIF)-homologue D-dopachrome tautomerase is a therapeutic target in a murine melanoma model Brief Reports

Sebastian Kobold, Melanie Merk, Luisa Hofer, Philip Peters, Richard Bucala, Stefan Endres

Published Dec 12, 2013 · Vol. 5, No. 1 · pp. 103-107

Keywords: Cytokine, MIF, cancer, apoptosis

Glycogen synthase kinase-3Î² inhibition depletes the population of prostate cancer stem/progenitor-like cells and attenuates metastatic growth Research Paper

Jan Kroon, Lars S. in 't Veld, Jeroen T. Buijs, Henry Cheung, Geertje van der Horst, Gabri van der Pluijm

Published Dec 5, 2013 · Vol. 5, No. 19 · pp. 8986-8994

Keywords: Cancer Stem Cells, GSK-3Î², Metastasis, Prostate Cancer, Wnt signaling

ERG induces a mesenchymal-like state associated with chemoresistance in leukemia cells Research Paper

Liliana H. Mochmann, Martin Neumann, Eva K. von Der Heide, Verena Nowak, Anja A. KÃ¼hl, Jutta Ortiz-Tanchez, Juliane Bock, Wolf K Hofmann, Claudia D Baldus

Published Dec 4, 2013 · Vol. 5, No. 2 · pp. 351-362

Keywords: ERG, ERK, EMT, Chemoresistance

The proto-oncogene KRAS is targeted by miR-200c Research Paper

Florian Kopp, Ernst Wagner, Andreas Roidl

Published Nov 24, 2013 · Vol. 5, No. 1 · pp. 185-195

Keywords: breast cancer, lung cancer, miRNA, K-ras, cell cycle, proliferation

A novel immunomodulatory and molecularly targeted strategy for refractory Hodgkinâ€™s lymphoma Brief Reports

Vivek Subbiah, Robert E. Brown, Mary F. McGuire, Jamie Buryanek, Filip Janku, Anas Younes, David Hong

Published Nov 19, 2013 · Vol. 5, No. 1 · pp. 95-102

Keywords: Hodgkin's lymphoma, mTOR, HDAC, Sirolimus, Vorinostat, Targeted therapy

KMT2D maintains neoplastic cell proliferation and global histone H3 lysine 4 monomethylation Research Paper

Changcun Guo, Lee H. Chen, Yafen Huang, Chun-Chi Chang, Ping Wang, Christopher J. Pirozzi, Xiaoxia Qin, Xuhui Bao, Paula K. Greer, Roger E. McLendon, Hai Yan, Stephen T. Keir, Darell D. Bigner, Yiping He

Published Nov 3, 2013 · Vol. 4, No. 11 · pp. 2144-2153

Keywords: MLL2, isogenic cell line, gene knockout, enhancer

Indoleamine 2,3-dioxygenase 1 (IDO1) activity in leukemia blasts correlates with poor outcome in childhood acute myeloid leukemia Research Paper

Valentina Folgiero, Bianca M. Goffredo, Perla Filippini, Riccardo Masetti, Giuseppina Bonanno, Roberta Caruso, Valentina Bertaina, Angela Mastronuzzi, Stefania Gaspari, Marco Zecca, Giovanni F Torelli, Anna M Testi, Andrea Pession, Franco Locatelli, Sergio Rutella

Published Oct 30, 2013 · Vol. 5, No. 8 · pp. 2052-2064

Keywords: Acute myeloid leukemia, IDO1, immune escape, regulatory T cells

A potential therapeutic strategy for chronic lymphocytic leukemia by combining Idelalisib and GS-9973, a novel spleen tyrosine kinase (Syk) inhibitor Research Paper

Russell T Burke, Marc M Loriaux, Kevin S Currie, Scott A Mitchell, Patricia Maciejewski, Astrid S Clarke, Julie A DiPaolo, Brian J Druker, Stephen E Spurgeon, Brian J Lannutti

Published Oct 30, 2013 · Vol. 5, No. 4 · pp. 908-915

Keywords: Chronic Lymphocytic Leukemia, B-cell receptor, signaling pathways, spleen tyrosine kinase, PI3 kinase

Impaired angiogenesis and tumor development by inhibition of the mitotic kinesin Eg5 Research Paper

Prisca Exertier, Sophie Javerzat, Baigang Wang, MÃ©lanie Franco, John M. Herbert, Natalia Platonova, Marie Winandy, NadÃ¨ge Pujol, Olivier Nivelles, Sandra Ormenese, Virginie Godard, JÃ¼rgen Becker, Roy Bicknell, Raphael Pineau, JÃ¶rg Wilting, Andreas Bikfalvi, Martin Hagedorn

Published Oct 26, 2013 · Vol. 4, No. 12 · pp. 2302-2316

Keywords: Angiogenesis, Eg5 kinesin, Mklp2 kinesin, VEGF, ispinesib

A lovastatin-elicited genetic program inhibits M2 macrophage polarization and enhances T cell infiltration into spontaneous mouse mammary tumors Research Paper

Emilia Mira, Lorena Carmona-RodrÃguez, Manuel TardÃ¡guila, IÃ±igo Azcoitia, Alicia GonzÃ¡lez-MartÃn, Luis Almonacid, Josefina Casas, Gemma FabriÃ¡s, Santos MaÃ±es

Published Oct 26, 2013 · Vol. 4, No. 12 · pp. 2288-2301

Keywords: Placental growth factor, statins, immunity, macrophage polarization, inflammation

Apoptotic circulating tumor cells (CTCs) in the peripheral blood of metastatic colorectal cancer patients are associated with liver metastasis but not CTCs Research Paper

Joshua E. E. Allen, Bikramajit Singh Saroya, Miriam Kunkel, David . T. Dicker, Avisnata Das, Kristi L. Peters, Jamal Joudeh, Junjia Zhu, Wafik S. El-Deiry

Published Oct 17, 2013 · Vol. 5, No. 7 · pp. 1753-1760

Cholesterol-induced mammary tumorigenesis is enhanced by adiponectin deficiency: role of LDL receptor upregulation Research Paper

Jing Liu, Aimin Xu, Karen Siu-Ling Lam, Nai-Sum Wong, Jie Chen, Peter R R Shepherd, Yu Wang

Published Oct 1, 2013 · Vol. 4, No. 10 · pp. 1804-1818

Keywords: Adiponectin, breast cancer, autophagy, cholesterol, LDLR

MYCN is a novel oncogenic target in pediatric T-cell Acute Lymphoblastic Leukemia Research Paper

Annalisa Astolfi, Francesca Vendemini, Milena Urbini, Fraia Melchionda, Riccardo Masetti, Monica Franzoni, Virginia Libri, Salvatore Serravalle, Marco Togni, Giuseppina Paone, Luca Montemurro, Daniela Bressanin, Francesca Chiarini, Alberto M Martelli, Roberto Tonelli, Andrea Pession

Published Sep 29, 2013 · Vol. 5, No. 1 · pp. 120-130

Keywords: pediatric T-ALL, MYCN, peptide nucleic acid, TAL1

Immunological targeting of tumor cells undergoing an epithelial-mesenchymal transition via a recombinant brachyury-yeast vaccine Research Paper

Duane H. Hamilton, Mary T. Litzinger, Alessandra Jales, Bruce Huang, Romaine I. Fernando, James W. Hodge, Andressa Ardiani, David Apelian, Jeffrey Schlom, Claudia Palena

Published Sep 26, 2013 · Vol. 4, No. 10 · pp. 1777-1790

Keywords: epithelial-mesenchymal transition, brachyury, T-box transcription factor, cancer vaccine, T-cell immunotherapy

Coordinated Targeting of the EGFR Signaling Axis by MicroRNA-27a* Research Paper

Xiaoli Wu, Mihir K. Bhayani, Cristina T. Dodge, Milena S. Nicoloso, Yunyun Chen, Xiaofeng Yan, Makoto Adachi, Ligy Thomas, Chad E. Galer, Tilahun Jiffar, Curtis R. Pickering, Michael E. Kupferman, Jeffrey N. Myers, George A. Calin, Stephen Y. Lai

Published Aug 6, 2013 · Vol. 4, No. 9 · pp. 1388-1398

Keywords: miRNA EGFR AKT1 mTOR miRNA-27a* miRNA-27a-5p

Crucial Role for Early Growth Response-1 in the Transcriptional Regulation of miR-20b in Breast Cancer Research Paper

Dongping Li, Yaroslav Ilnytskyy, Anna Kovalchuk, Levon M. Khachigian, Roderick T. Bronson, Bo Wang, Olga Kovalchuk

Published Jul 28, 2013 · Vol. 4, No. 9 · pp. 1373-1387

Keywords: EGR1, miR-20b, transcription, PTEN, BRCA1, breast cancer, proliferation, migration, cell cycle arrest

Adoptive T-cell therapy to treat liver cancer: Is the liver microenvironment key? Editorial

Gerald Willimsky, Ulrike Protzer, Percy Knolle, Mathias Heikenwalder

Published Jul 15, 2013 · Vol. 4, No. 8 · pp. 1117-1118

Posttranslational modification and conformational state of Heat Shock Protein 90 differentially affect binding of chemically diverse small molecule inhibitors Research Paper

Kristin Beebe, Mehdi Mollapour, Bradley Scroggins, Chrisostomos Prodromou, Wanping Xu, Mari Tokita, Tony Taldone, Lester Pullen, Bettina K Zierer, Min-Jung Lee, Jane Trepel, Johannes Buchner, Daniel Bolon, Gabriela Chiosis, Len Neckers

Published Jul 7, 2013 · Vol. 4, No. 7 · pp. 1065-1074

Keywords: Hsp90, posttranslational modification, phosphorylation, drug binding, Hsp90 inhibitor

Plasma Membrane Proteomics Identifies Biomarkers Associated with MMSET Overexpression in T(4;14) Multiple Myeloma Research Paper

Zhigang Xie, Jayantha Gunaratne, Lip Lee Cheong, Shaw Cheng Liu, Tze Loong Koh, Gaofeng Huang, Walter P Blackstock, Wee Joo Chng

Published Jun 26, 2013 · Vol. 4, No. 7 · pp. 1008-1018

Keywords: SILAC, quantitative proteomics, oncotargets, multiple myeloma

Therapy-resistant acute lymphoblastic leukemia (ALL) cells inactivate FOXO3 to escape apoptosis induction by TRAIL and Noxa Research Paper

Michael J Ausserlechner, Christina Salvador, Andrea Deutschmann, Martin Bodner, Giampietro Viola, Roberta Bortolozzi, Guiseppe Basso, Judith Hagenbuchner, Petra Obexer

Published Jun 25, 2013 · Vol. 4, No. 7 · pp. 995-1007

Keywords: FOXO3/FKHRL1, T-ALL, p16/INK4A, BH3-only proteins, TRAIL

Publication Alerts

European Cancer and Oncology Congress

Post-Publication Promotion

Search Oncotarget

The macrophage migration inhibitory factor (MIF)-homologue D-dopachrome tautomerase is a therapeutic target in a murine melanoma model Brief Reports

Glycogen synthase kinase-3Î² inhibition depletes the population of prostate cancer stem/progenitor-like cells and attenuates metastatic growth Research Paper

ERG induces a mesenchymal-like state associated with chemoresistance in leukemia cells Research Paper

The proto-oncogene KRAS is targeted by miR-200c Research Paper

A novel immunomodulatory and molecularly targeted strategy for refractory Hodgkinâ€™s lymphoma Brief Reports

KMT2D maintains neoplastic cell proliferation and global histone H3 lysine 4 monomethylation Research Paper

Indoleamine 2,3-dioxygenase 1 (IDO1) activity in leukemia blasts correlates with poor outcome in childhood acute myeloid leukemia Research Paper

A potential therapeutic strategy for chronic lymphocytic leukemia by combining Idelalisib and GS-9973, a novel spleen tyrosine kinase (Syk) inhibitor Research Paper

Impaired angiogenesis and tumor development by inhibition of the mitotic kinesin Eg5 Research Paper

A lovastatin-elicited genetic program inhibits M2 macrophage polarization and enhances T cell infiltration into spontaneous mouse mammary tumors Research Paper

Apoptotic circulating tumor cells (CTCs) in the peripheral blood of metastatic colorectal cancer patients are associated with liver metastasis but not CTCs Research Paper

Cholesterol-induced mammary tumorigenesis is enhanced by adiponectin deficiency: role of LDL receptor upregulation Research Paper

MYCN is a novel oncogenic target in pediatric T-cell Acute Lymphoblastic Leukemia Research Paper

Immunological targeting of tumor cells undergoing an epithelial-mesenchymal transition via a recombinant brachyury-yeast vaccine Research Paper

Coordinated Targeting of the EGFR Signaling Axis by MicroRNA-27a* Research Paper

Crucial Role for Early Growth Response-1 in the Transcriptional Regulation of miR-20b in Breast Cancer Research Paper

Adoptive T-cell therapy to treat liver cancer: Is the liver microenvironment key? Editorial

Posttranslational modification and conformational state of Heat Shock Protein 90 differentially affect binding of chemically diverse small molecule inhibitors Research Paper

Plasma Membrane Proteomics Identifies Biomarkers Associated with MMSET Overexpression in T(4;14) Multiple Myeloma Research Paper

Therapy-resistant acute lymphoblastic leukemia (ALL) cells inactivate FOXO3 to escape apoptosis induction by TRAIL and Noxa Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

The macrophage migration inhibitory factor (MIF)-homologue D-dopachrome tautomerase is a therapeutic target in a murine melanoma model Brief Reports

Glycogen synthase kinase-3Î² inhibition depletes the population of prostate cancer stem/progenitor-like cells and attenuates metastatic growth Research Paper

ERG induces a mesenchymal-like state associated with chemoresistance in leukemia cells Research Paper

The proto-oncogene KRAS is targeted by miR-200c Research Paper

A novel immunomodulatory and molecularly targeted strategy for refractory Hodgkinâ€™s lymphoma Brief Reports

KMT2D maintains neoplastic cell proliferation and global histone H3 lysine 4 monomethylation Research Paper

Indoleamine 2,3-dioxygenase 1 (IDO1) activity in leukemia blasts correlates with poor outcome in childhood acute myeloid leukemia Research Paper

A potential therapeutic strategy for chronic lymphocytic leukemia by combining Idelalisib and GS-9973, a novel spleen tyrosine kinase (Syk) inhibitor Research Paper

Impaired angiogenesis and tumor development by inhibition of the mitotic kinesin Eg5 Research Paper

A lovastatin-elicited genetic program inhibits M2 macrophage polarization and enhances T cell infiltration into spontaneous mouse mammary tumors Research Paper

Apoptotic circulating tumor cells (CTCs) in the peripheral blood of metastatic colorectal cancer patients are associated with liver metastasis but not CTCs Research Paper

Cholesterol-induced mammary tumorigenesis is enhanced by adiponectin deficiency: role of LDL receptor upregulation Research Paper

MYCN is a novel oncogenic target in pediatric T-cell Acute Lymphoblastic Leukemia Research Paper

Immunological targeting of tumor cells undergoing an epithelial-mesenchymal transition via a recombinant brachyury-yeast vaccine Research Paper

Coordinated Targeting of the EGFR Signaling Axis by MicroRNA-27a* Research Paper

Crucial Role for Early Growth Response-1 in the Transcriptional Regulation of miR-20b in Breast Cancer Research Paper

Adoptive T-cell therapy to treat liver cancer: Is the liver microenvironment key? Editorial

Posttranslational modification and conformational state of Heat Shock Protein 90 differentially affect binding of chemically diverse small molecule inhibitors Research Paper

Plasma Membrane Proteomics Identifies Biomarkers Associated with MMSET Overexpression in T(4;14) Multiple Myeloma Research Paper

Therapy-resistant acute lymphoblastic leukemia (ALL) cells inactivate FOXO3 to escape apoptosis induction by TRAIL and Noxa Research Paper