The Oncosearch | Oncotarget

Targeted inhibition of cell-surface serine protease Hepsin blocks prostate cancer bone metastasis Research Paper

Xi Tang, Sumit S. Mahajan, Liem T. Nguyen, FranÃ§ois BÃ©liveau, Richard Leduc, Julian A. Simon, Valeri Vasioukhin

Published Mar 16, 2014 · Vol. 5, No. 5 · pp. 1352-1362

C1GALT1 overexpression promotes the invasive behavior of colon cancer cells through modifying O-glycosylation of FGFR2 Research Paper

Ji-Shiang Hung, John Huang, Yo-Chuen Lin, Miao-Juei Huang, Po-Huang Lee, Hong-Shiee Lai, Jin-Tung Liang, Min-Chuan Huang

Published Mar 15, 2014 · Vol. 5, No. 8 · pp. 2096-2106

Anastrozole and everolimus in advanced gynecologic and breast malignancies: activity and molecular alterations in the PI3K/AKT/mTOR pathway Research Paper

Jennifer J. Wheler, Stacy L. Moulder, Aung Naing, Filip Janku, Sarina A. Piha-Paul, Gerald S. Falchook, Ralph Zinner, Apostolia M. Tsimberidou, Siqing Fu, David S. Hong, Johnique T. Atkins, Roman Yelensky, Philip J. Stephens, Razelle Kurzrock

Published Mar 14, 2014 · Vol. 5, No. 10 · pp. 3029-3038

Targeting of multiple myeloma-related angiogenesis by miR-199a-5p mimics: in vitro and in vivo anti-tumor activity Research Paper

Lavinia Raimondi, Nicola Amodio, Teresa Di Martino, Emanuela Altomare, Marzia Leotta, Daniele Caracciolo, Annamaria GullÃ, Antonino Neri, Simona Taverna, Riccardo Alessandro, Antonio Giordano, Pierosandro Tagliaferri, Pierfrancesco Tassone

Published Mar 14, 2014 · Vol. 5, No. 10 · pp. 3039-3054

Keywords: miR-199-5p, microRNA, miRNA, multiple myeloma, plasma cell leukemia, microenviroment, hypoxia, angiogenesis

Linking differential radiation responses to glioma heterogeneity Research Paper

Chao Ke, Katherine Tran, Yumay Chen, Anne T. Di Donato, Liping Yu, Yuanjie Hu, Mark E. Linskey, Ping H. Wang, Charles L. Limoli, Yi-Hong Zhou

Published Mar 12, 2014 · Vol. 5, No. 6 · pp. 1657-1665

Role of aberrant PI3K pathway activation in gallbladder tumorigenesis Priority Research Paper

Andrea Lunardi, Kaitlyn A. Webster, Antonella Papa, Bhavik Padmani, John G. Clohessy, Roderick T. Bronson, Pier Paolo Pandolfi

Published Mar 10, 2014 · Vol. 5, No. 4 · pp. 894-900

Retaining MKP1 expression and attenuating JNK-mediated apoptosis by RIP1 for cisplatin resistance through miR-940 inhibition Research Paper

Qiong Wang, Shaoqing Shi, Weiyang He, Mabel T. Padilla, Lin Zhang, Xia Wang, Bin Zhang, Yong Lin

Published Feb 25, 2014 · Vol. 5, No. 5 · pp. 1304-1314

WNT signaling and distant metastasis in colon cancer through transcriptional activity of nuclear Î²-Catenin depend on active PI3K signaling Research Paper

Steffen Ormanns, Jens Neumann, David Horst, Thomas Kirchner, Andreas Jung

Published Feb 19, 2014 · Vol. 5, No. 10 · pp. 2999-3011

Keywords: WNT, Î²-Catenin, PI3K, colon cancer, metastasis

TBX2 represses CST6 resulting in uncontrolled legumain activity to sustain breast cancer proliferation: a novel cancer-selective target pathway with therapeutic opportunities Research Paper

Zenobia C. D'Costa, Catherine A. Higgins, Chee Wee Ong, Gareth Irwin, David Boyle, Darragh G. McArt, Karen McCloskey, Niamh E. Buckley, Nyree T. Crawford, Lalitha Thiagarajan, James T. Murray, Richard D. Kennedy, Karl A. Mulligan, Denis P. Harkin, David J.J. Waugh, Chris J. Scott, Manuel Salto-Tellez, Richard Williams, Paul B. Mullan

Published Feb 8, 2014 · Vol. 5, No. 6 · pp. 1609-1620

Keywords: TBX2, CST6, LGMN, breast cancer

Mutations in IDH1, IDH2, and in the TERT promoter define clinically distinct subgroups of adult malignant gliomas Research Paper

Patrick J. Killela, Christopher J. Pirozzi, Patrick Healy, Zachary J. Reitman, Eric Lipp, Ahmed B. Rasheed, Rui Yang, Bill H. Diplas, Zhaohui Wang, Paula K. Greer, Huishan Zhu, Catherine Y. Wang, Austin B. Carpenter, Henry Friedman, Allan H. Friedman, Stephen T. Keir, Jie He, Yiping He, Roger E. McLendon, James E. Herndon II, Hai Yan, Darell D. Bigner

Published Jan 28, 2014 · Vol. 5, No. 6 · pp. 1515-1525

Constitutive IDO expression in human cancer is sustained by an autocrine signaling loop involving IL-6, STAT3 and the AHR Research Paper

Ulrike M. Litzenburger, Christiane A. Opitz, Felix Sahm, Katharina J. Rauschenbach, Saskia Trump, Marcus Winter, Martina Ott, Katharina Ochs, Christian Lutz, Xiangdong Liu, Natasa Anastasov, Irina Lehmann, Thomas HÃ¶fer, Andreas von Deimling, Wolfgang Wick, Michael Platten

Published Jan 20, 2014 · Vol. 5, No. 4 · pp. 1038-1051

Keywords: IDO, immunosuppression, autoactivation loop

Immunogenicity of targeted lentivectors Research Paper

Cleo Goyvaerts, De Groeve Kurt, Sandra Van Lint, Carlo Heirman, Jo A. Van Ginderachter, Patrick De Baetselier, Geert Raes, Kris Thielemans, Karine Breckpot

Published Jan 19, 2014 · Vol. 5, No. 3 · pp. 704-715

Keywords: antitumor immunotherapy, lentiviral vectors, targeting, antigen-presenting cells

Indirect targeting of IGF receptor signaling in vivo by substrate-selective inhibition of PAPP-A proteolytic activity Research Paper

Jakob H. Mikkelsen, Zachary T. Resch, Bhanu Kalra, Gopal Savjani, Ajay Kumar, Cheryl A. Conover, Claus Oxvig

Published Jan 17, 2014 · Vol. 5, No. 4 · pp. 1014-1025

Keywords: insulin-like growth factor receptor, pregnancy-associated plasma protein-A, proteolytic inhibition, therapeutic antibody, xenograft mouse model

Post-transcriptional regulation of MRE11 expression in muscle-invasive bladder tumours Research Paper

Rebecca M. Martin, Martin Kerr, Mark T.W. Teo, Sarah J. Jevons, Marianne Koritzinsky, Bradly G. Wouters, Selina Bhattarai, Anne E. Kiltie

Published Jan 14, 2014 · Vol. 5, No. 4 · pp. 993-1003

Keywords: MRE11, bladder cancer, post-transcriptional regulation, microRNA, protein stability

Spores of Clostridium engineered for clinical efficacy and safety cause regression and cure of tumors in vivo Research Paper

John T. Heap, Jan Theys, Muhammad Ehsaan, Aleksandra M Kubiak, Ludwig Dubois, Kim Paesmans, Lieve Van Mellaert, Richard Knox, Sarah A. Kuehne, Phillipe Lambin, Nigel P. Minton

Published Jan 12, 2014 · Vol. 5, No. 7 · pp. 1761-1769

Radiation-induced immunogenic modulation of tumor enhances antigen processing and calreticulin exposure, resulting in enhanced T-cell killing Research Paper

Sofia R. Gameiro, Momodou L. Jammeh, Max M. Wattenberg, Kwong Y. Tsang, Soldano Ferrone, James W. Hodge

Published Dec 31, 2013 · Vol. 5, No. 2 · pp. 403-416

Keywords: radiation, immunogenic modulation, antigen-processing machinery, calreticulin, CTL, ER stress, PERK

Rac1b negatively regulates TGF-Î²1-induced cell motility in pancreatic ductal epithelial cells by suppressing Smad signalling Research Paper

Hendrik Ungefroren, Susanne Sebens, Klaudia Giehl, Ole Helm, Stephanie Groth, Fred Faendrich, Christoph Roecken, Bence Sipos, Hendrik Lehnert, Frank Gieseler

Published Dec 23, 2013 · Vol. 5, No. 1 · pp. 277-290

Keywords: Rac1b, Rac1, Smad, TGF-beta1, pancreatic ductal adenocarcinoma, cell migration

FOXP3 over-expression inhibits melanoma tumorigenesis via effects on proliferation and apoptosis. Research Paper

Bee Shin Tan, Matthew R Anaka, Siddhartha Deb, Claudia Freyer, Lisa M Ebert, Anderly C Chueh, Sheren Al-Obaidi, Andreas Behren, Aparna Jayachandran, Jonathan Cebon, Weisan Chen, John M Mariadason

Published Dec 20, 2013 · Vol. 5, No. 1 · pp. 264-276

Keywords: FOXP3, melanoma, proliferation, apoptosis

Lymphoid enhancer binding factor-1 (LEF1) expression as a prognostic factor in adult acute promyelocytic leukemia Research Paper

Francesco Albano, Antonella Zagaria, Luisa Anelli, Paola Orsini, Crescenzio F Minervini, Luciana Impera, Paola Casieri, Nicoletta Coccaro, Giuseppina Tota, Claudia Brunetti, Angela Minervini, Domenico Pastore, Paola Carluccio, Anna Mestice, Angelo Cellamare, Giorgina Specchia

Published Dec 19, 2013 · Vol. 5, No. 3 · pp. 649-658

Keywords: acute promyelocytic leukemia, LEF1, prognosis, outcome

Targeting chronic lymphocytic leukemia using CIGB-300, a clinical-stage CK2-specific cell-permeable peptide inhibitor Research Paper

Leila R. Martins, Yasser Perera, Paulo LÃºcio, Maria G. Silva, Silvio E. Perea, JoÃ£o T. Barata

Published Dec 13, 2013 · Vol. 5, No. 1 · pp. 258-263

Keywords: Chronic Lymphocytic Leukemia, CLL, Casein kinase 2, CK2, CIGB-300, Signaling therapies

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Targeted inhibition of cell-surface serine protease Hepsin blocks prostate cancer bone metastasis Research Paper

C1GALT1 overexpression promotes the invasive behavior of colon cancer cells through modifying O-glycosylation of FGFR2 Research Paper

Anastrozole and everolimus in advanced gynecologic and breast malignancies: activity and molecular alterations in the PI3K/AKT/mTOR pathway Research Paper

Targeting of multiple myeloma-related angiogenesis by miR-199a-5p mimics: in vitro and in vivo anti-tumor activity Research Paper

Linking differential radiation responses to glioma heterogeneity Research Paper

Role of aberrant PI3K pathway activation in gallbladder tumorigenesis Priority Research Paper

Retaining MKP1 expression and attenuating JNK-mediated apoptosis by RIP1 for cisplatin resistance through miR-940 inhibition Research Paper

WNT signaling and distant metastasis in colon cancer through transcriptional activity of nuclear Î²-Catenin depend on active PI3K signaling Research Paper

TBX2 represses CST6 resulting in uncontrolled legumain activity to sustain breast cancer proliferation: a novel cancer-selective target pathway with therapeutic opportunities Research Paper

Mutations in IDH1, IDH2, and in the TERT promoter define clinically distinct subgroups of adult malignant gliomas Research Paper

Constitutive IDO expression in human cancer is sustained by an autocrine signaling loop involving IL-6, STAT3 and the AHR Research Paper

Immunogenicity of targeted lentivectors Research Paper

Indirect targeting of IGF receptor signaling in vivo by substrate-selective inhibition of PAPP-A proteolytic activity Research Paper

Post-transcriptional regulation of MRE11 expression in muscle-invasive bladder tumours Research Paper

Spores of Clostridium engineered for clinical efficacy and safety cause regression and cure of tumors in vivo Research Paper

Radiation-induced immunogenic modulation of tumor enhances antigen processing and calreticulin exposure, resulting in enhanced T-cell killing Research Paper

Rac1b negatively regulates TGF-Î²1-induced cell motility in pancreatic ductal epithelial cells by suppressing Smad signalling Research Paper

FOXP3 over-expression inhibits melanoma tumorigenesis via effects on proliferation and apoptosis. Research Paper

Lymphoid enhancer binding factor-1 (LEF1) expression as a prognostic factor in adult acute promyelocytic leukemia Research Paper

Targeting chronic lymphocytic leukemia using CIGB-300, a clinical-stage CK2-specific cell-permeable peptide inhibitor Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Targeted inhibition of cell-surface serine protease Hepsin blocks prostate cancer bone metastasis Research Paper

C1GALT1 overexpression promotes the invasive behavior of colon cancer cells through modifying O-glycosylation of FGFR2 Research Paper

Anastrozole and everolimus in advanced gynecologic and breast malignancies: activity and molecular alterations in the PI3K/AKT/mTOR pathway Research Paper

Targeting of multiple myeloma-related angiogenesis by miR-199a-5p mimics: in vitro and in vivo anti-tumor activity Research Paper

Linking differential radiation responses to glioma heterogeneity Research Paper

Role of aberrant PI3K pathway activation in gallbladder tumorigenesis Priority Research Paper

Retaining MKP1 expression and attenuating JNK-mediated apoptosis by RIP1 for cisplatin resistance through miR-940 inhibition Research Paper

WNT signaling and distant metastasis in colon cancer through transcriptional activity of nuclear Î²-Catenin depend on active PI3K signaling Research Paper

TBX2 represses CST6 resulting in uncontrolled legumain activity to sustain breast cancer proliferation: a novel cancer-selective target pathway with therapeutic opportunities Research Paper

Mutations in IDH1, IDH2, and in the TERT promoter define clinically distinct subgroups of adult malignant gliomas Research Paper

Constitutive IDO expression in human cancer is sustained by an autocrine signaling loop involving IL-6, STAT3 and the AHR Research Paper

Immunogenicity of targeted lentivectors Research Paper

Indirect targeting of IGF receptor signaling in vivo by substrate-selective inhibition of PAPP-A proteolytic activity Research Paper

Post-transcriptional regulation of MRE11 expression in muscle-invasive bladder tumours Research Paper

Spores of Clostridium engineered for clinical efficacy and safety cause regression and cure of tumors in vivo Research Paper

Radiation-induced immunogenic modulation of tumor enhances antigen processing and calreticulin exposure, resulting in enhanced T-cell killing Research Paper

Rac1b negatively regulates TGF-Î²1-induced cell motility in pancreatic ductal epithelial cells by suppressing Smad signalling Research Paper

FOXP3 over-expression inhibits melanoma tumorigenesis via effects on proliferation and apoptosis. Research Paper

Lymphoid enhancer binding factor-1 (LEF1) expression as a prognostic factor in adult acute promyelocytic leukemia Research Paper

Targeting chronic lymphocytic leukemia using CIGB-300, a clinical-stage CK2-specific cell-permeable peptide inhibitor Research Paper