The Oncosearch | Oncotarget

Inhibition of protein kinase II (CK2) prevents induced signal transducer and activator of transcription (STAT) 1/3 and constitutive STAT3 activation Research Paper

Samadhi Aparicio-Siegmund, Jan Sommer, Niloufar Monhasery, Ralf Schwanbeck, Eric Keil, David FinkenstÃ¤dt, Klaus Pfeffer, Stefan Rose-John, JÃ¼rgen Scheller, Christoph Garbers

Published Mar 23, 2014 · Vol. 5, No. 8 · pp. 2131-2148

Dual Aurora A and JAK2 kinase blockade effectively suppresses malignant transformation Research Paper

Hua Yang, Harshani Lawrence, Aslamuzzaman Kazi, Harsukh Gevariya, Ronil Patel, Yunting Luo, Uwe Rix, Ernst Schonbrunn, Nicholas J. Lawrence, Said M Sebti

Published Mar 22, 2014 · Vol. 5, No. 10 · pp. 2947-2961

STAT3 down regulates LC3 to inhibit autophagy and pancreatic cancer cell growth Research Paper

Jingjing Gong, Amanda R. MuÃ±oz, Daniel Chan, Rita Ghosh, Addanki P. Kumar

Published Mar 15, 2014 · Vol. 5, No. 9 · pp. 2529-2541

Targeting Aerobic Glycolysis and HIF-1Î± Expression Enhance Imiquimod-induced Apoptosis in Cancer Cells Research Paper

Shi-Wei Huang, Jun-Kai Kao, Chun-Ying Wu, Sin-Ting Wang, Hsin-Chen Lee, Shu-Mei Liang, Yi-Ju Chen, Jeng-Jer Shieh

Published Mar 12, 2014 · Vol. 5, No. 5 · pp. 1363-1381

Keywords: imiquimod, aerobic glycolysis, HIF-1alpha, ï€¬ï€ apoptosis

A high-content morphological screen identifies novel microRNAs that regulate neuroblastoma cell differentiation Research Paper

Zhenze Zhao, Xiuye Ma, Tzu-Hung Hsiao, Gregory Lin, Adam Kosti, Xiaojie Yu, Uthra Suresh, Yidong Chen, Gail E. Tomlinson, Alexander Pertsemlidis, Liqin Du

Published Feb 28, 2014 · Vol. 5, No. 9 · pp. 2499-2512

Keywords: neuroblastoma, microRNA, high-content screen, differentiation, differentiation therapy

Constitutive IDO expression in human cancer is sustained by an autocrine signaling loop involving IL-6, STAT3 and the AHR Research Paper

Ulrike M. Litzenburger, Christiane A. Opitz, Felix Sahm, Katharina J. Rauschenbach, Saskia Trump, Marcus Winter, Martina Ott, Katharina Ochs, Christian Lutz, Xiangdong Liu, Natasa Anastasov, Irina Lehmann, Thomas HÃ¶fer, Andreas von Deimling, Wolfgang Wick, Michael Platten

Published Jan 20, 2014 · Vol. 5, No. 4 · pp. 1038-1051

Keywords: IDO, immunosuppression, autoactivation loop

Gefitinib resistance resulted from STAT3-mediated Akt activation in lung cancer cells Research Paper

Kai Wu, Qingshan Chang, Yongju Lu, Ping Qiu, Bailing Chen, Chitra Thakur, Jiaying Sun, Lingzhi Li, Anjaneyulu Kowluru, Fei Chen

Published Nov 24, 2013 · Vol. 4, No. 12 · pp. 2430-2438

Keywords: Gefitinib, EGFR, STAT3, Akt recovery

Indoleamine 2,3-dioxygenase 1 (IDO1) activity in leukemia blasts correlates with poor outcome in childhood acute myeloid leukemia Research Paper

Valentina Folgiero, Bianca M. Goffredo, Perla Filippini, Riccardo Masetti, Giuseppina Bonanno, Roberta Caruso, Valentina Bertaina, Angela Mastronuzzi, Stefania Gaspari, Marco Zecca, Giovanni F Torelli, Anna M Testi, Andrea Pession, Franco Locatelli, Sergio Rutella

Published Oct 30, 2013 · Vol. 5, No. 8 · pp. 2052-2064

Keywords: Acute myeloid leukemia, IDO1, immune escape, regulatory T cells

Targeting IL-11 signaling in colon cancer Editorial Materials

Matthias Ernst, Tracy L. Putoczki

Published Oct 26, 2013 · Vol. 4, No. 11 · pp. 1860-1861

Keywords: Colon cancer, anti-cytokine therapy, interleukin-11, Stat3

Secretome from senescent melanoma engages the STAT3 pathway to favor reprogramming of naive melanoma towards a tumor-initiating cell phenotype. Research Paper

MickaÃ«l Ohanna, Yann Cheli, Caroline Bonet, Vanessa F Bonazzi, Marylin Allegra, Sandy Giuliano, Karine Bille, Philippe Bahadoran, Damien Giacchero, Jean Philippe Lacour, Glen M Boyle, Nicholas F Hayward, Corine Bertolotto, Robert Ballotti

Published Aug 19, 2013 · Vol. 4, No. 12 · pp. 2212-2224

Keywords: melanoma, senescence, secretome, STAT3

STAT6-mediated BCL6 repression in primary mediastinal B-cell lymphoma (PMBL) Research Paper

Olga Ritz, Karolin Rommel, Karola Dorsch, Elena Kelsch, Julia Melzner, Michaela Buck, Karen Leroy, Vasiliki Papadopoulou, Simon Wagner, Jochen K Lennerz, Peter MÃ¶ller

Published Jul 13, 2013 · Vol. 4, No. 7 · pp. 1093-1102

Keywords: intratumoral heterogenity, PMBL, BCL6, pSTAT6

Germline PTPRD Mutations in Ewing Sarcoma: Biologic and Clinical Implications Research Paper

Yunyun Jiang, Filip Janku, Vivek Subbiah, Laura S. Angelo, Aung Naing, Peter M. Anderson, Cynthia E. Herzog, Siqing Fu, Robert S. Benjamin, Razelle Kurzrock

Published Jun 5, 2013 · Vol. 4, No. 6 · pp. 884-889

Keywords: Ewing sarcoma, PTPRD, mutation, germline

STAT5b in LGL leukemia â€“ a novel therapeutic target? Editorial

Hanna L. M. Rajala, Satu Mustjoki

Published May 16, 2013 · Vol. 4, No. 6 · pp. 808-809

Inhibition of STAT3 with orally active JAK inhibitor, AZD1480, decreases tumor growth in Neuroblastoma and Pediatric Sarcomas In vitro and In vivo Research Paper

Shuang Yan, Zhijie Li, Carol J Thiele

Published Mar 19, 2013 · Vol. 4, No. 3 · pp. 433-445

Keywords: neuroblastoma, Ewing sarcoma, rhabdomyosarcoma, JAK inhibitor, STAT3

Identification of miR-30d as a novel prognostic maker of prostate cancer. Research Paper

Naohito Kobayashi, Hiroji Uemura, Kiyotaka Nagahama, Koji Okudela, Mitsuko Furuya, Yoko Ino, Yusuke Ito, Hisashi Hirano, Yoshiaki Inayama, Ichiro Aoki, Yoji Nagashima, Yoshinobu Kubota, Hitoshi Ishiguro

Published Nov 17, 2012 · Vol. 3, No. 11 · pp. 1455-1471

Keywords: miRNA-30d, prostate cancer, biochemical recurrence, SOCS1

Modulating Antiangiogenic Resistance by Inhibiting the Signal Transducer and Activator of Transcription 3 Pathway in Glioblastoma Research Paper

John de Groot, Ji Liang, Ling-Yuan Kong, Jun Wei, Yuji Piao, Gregory Fuller, Wei Qiao, Amy B Heimberger

Published Sep 19, 2012 · Vol. 3, No. 9 · pp. 1036-1048

Keywords: bevacizumab, anti-vascular endothelial growth factor, signal transducer and activator of transcription 3, treatment failure, invasion

Targeting of Rac GTPases blocks the spread of intact human breast cancer Research Paper

Elad Katz, Andrew H. Sims, Duncan Sproul, Helen Caldwell, J. Michael Dixon, Richard R. Meehan, David J. Harrison

Published Jun 9, 2012 · Vol. 3, No. 6 · pp. 608-619

Keywords: breast cancer, gtpases, rac1, stat3, invasion

Pro-malignant properties of STAT3 during chronic inflammation Editorial Comments

Marco Demaria, Valeria Poli

Published Apr 20, 2012 · Vol. 3, No. 4 · pp. 359-360

Keywords: Stat3, cancer, inflammation, Hif-1alpha, aerobic glycolysis

The Expression of p-STAT3 in Stage IV Melanoma: Risk of CNS Metastasis and Survival Research Paper

Ian Lee, Patricia S. Fox, Sherise D. Ferguson, Roland L. Bassett, Jr., Ling-Yuan Kong, Christopher W. Schacherer, Jeffrey E. Gershenwald, Elizabeth A. Grimm, Gregory N. Fuller, Amy B. Heimberger

Published Apr 6, 2012 · Vol. 3, No. 3 · pp. 336-344

Keywords: melanoma, p-STAT3, CNS metastasis, prognosis

Germline mutations in the oncogene EZH2 cause Weaver syndrome and increased human height Research Paper

Katrina Tatton-Brown, Sandra Hanks, Elise Ruark, Anna Zachariou, Silvana Del Vecchio Duarte, Emma Ramsay, Katie Snape, Anne Murray, Elizabeth R. Perdeaux, Sheila Seal, Chey Loveday, Siddharth Banka, Carol Clericuzio, Frances Flinter, Alex Magee, Vivienne McConnell, Michael Patton, Wolfgang Raith, Julia Rankin, Miranda Splitt, Volker Strenger, Clare Taylor, Patricia Wheeler, I. Karen Temple, Trevor Cole, Jenny Douglas, Nazneen Rahman

Published Dec 21, 2011 · Vol. 2, No. 12 · pp. 1127-1133

Keywords: EZH2, Weaver syndrome, height, myeloid malignancies, histone methyltransferase

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Inhibition of protein kinase II (CK2) prevents induced signal transducer and activator of transcription (STAT) 1/3 and constitutive STAT3 activation Research Paper

Dual Aurora A and JAK2 kinase blockade effectively suppresses malignant transformation Research Paper

STAT3 down regulates LC3 to inhibit autophagy and pancreatic cancer cell growth Research Paper

Targeting Aerobic Glycolysis and HIF-1Î± Expression Enhance Imiquimod-induced Apoptosis in Cancer Cells Research Paper

A high-content morphological screen identifies novel microRNAs that regulate neuroblastoma cell differentiation Research Paper

Constitutive IDO expression in human cancer is sustained by an autocrine signaling loop involving IL-6, STAT3 and the AHR Research Paper

Gefitinib resistance resulted from STAT3-mediated Akt activation in lung cancer cells Research Paper

Indoleamine 2,3-dioxygenase 1 (IDO1) activity in leukemia blasts correlates with poor outcome in childhood acute myeloid leukemia Research Paper

Targeting IL-11 signaling in colon cancer Editorial Materials

Secretome from senescent melanoma engages the STAT3 pathway to favor reprogramming of naive melanoma towards a tumor-initiating cell phenotype. Research Paper

STAT6-mediated BCL6 repression in primary mediastinal B-cell lymphoma (PMBL) Research Paper

Germline PTPRD Mutations in Ewing Sarcoma: Biologic and Clinical Implications Research Paper

STAT5b in LGL leukemia â€“ a novel therapeutic target? Editorial

Inhibition of STAT3 with orally active JAK inhibitor, AZD1480, decreases tumor growth in Neuroblastoma and Pediatric Sarcomas In vitro and In vivo Research Paper

Identification of miR-30d as a novel prognostic maker of prostate cancer. Research Paper

Modulating Antiangiogenic Resistance by Inhibiting the Signal Transducer and Activator of Transcription 3 Pathway in Glioblastoma Research Paper

Targeting of Rac GTPases blocks the spread of intact human breast cancer Research Paper

Pro-malignant properties of STAT3 during chronic inflammation Editorial Comments

The Expression of p-STAT3 in Stage IV Melanoma: Risk of CNS Metastasis and Survival Research Paper

Germline mutations in the oncogene EZH2 cause Weaver syndrome and increased human height Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Inhibition of protein kinase II (CK2) prevents induced signal transducer and activator of transcription (STAT) 1/3 and constitutive STAT3 activation Research Paper

Dual Aurora A and JAK2 kinase blockade effectively suppresses malignant transformation Research Paper

STAT3 down regulates LC3 to inhibit autophagy and pancreatic cancer cell growth Research Paper

Targeting Aerobic Glycolysis and HIF-1Î± Expression Enhance Imiquimod-induced Apoptosis in Cancer Cells Research Paper

A high-content morphological screen identifies novel microRNAs that regulate neuroblastoma cell differentiation Research Paper

Constitutive IDO expression in human cancer is sustained by an autocrine signaling loop involving IL-6, STAT3 and the AHR Research Paper

Gefitinib resistance resulted from STAT3-mediated Akt activation in lung cancer cells Research Paper

Indoleamine 2,3-dioxygenase 1 (IDO1) activity in leukemia blasts correlates with poor outcome in childhood acute myeloid leukemia Research Paper

Targeting IL-11 signaling in colon cancer Editorial Materials

Secretome from senescent melanoma engages the STAT3 pathway to favor reprogramming of naive melanoma towards a tumor-initiating cell phenotype. Research Paper

STAT6-mediated BCL6 repression in primary mediastinal B-cell lymphoma (PMBL) Research Paper

Germline PTPRD Mutations in Ewing Sarcoma: Biologic and Clinical Implications Research Paper

STAT5b in LGL leukemia â€“ a novel therapeutic target? Editorial

Inhibition of STAT3 with orally active JAK inhibitor, AZD1480, decreases tumor growth in Neuroblastoma and Pediatric Sarcomas In vitro and In vivo Research Paper

Identification of miR-30d as a novel prognostic maker of prostate cancer. Research Paper

Modulating Antiangiogenic Resistance by Inhibiting the Signal Transducer and Activator of Transcription 3 Pathway in Glioblastoma Research Paper

Targeting of Rac GTPases blocks the spread of intact human breast cancer Research Paper

Pro-malignant properties of STAT3 during chronic inflammation Editorial Comments

The Expression of p-STAT3 in Stage IV Melanoma: Risk of CNS Metastasis and Survival Research Paper

Germline mutations in the oncogene EZH2 cause Weaver syndrome and increased human height Research Paper