The Oncosearch | Oncotarget

Brassinin inhibits STAT3 signaling pathway through modulation of PIAS-3 and SOCS-3 expression and sensitizes human lung cancer xenograft in nude mice to paclitaxel Research Paper

Jong Hyun Lee, Chulwon Kim, Gautam Sethi, Kwang Seok Ahn

Published Jan 31, 2015 · Vol. 6, No. 8 · pp. 6386-6405

Cisplatin-selected resistance is associated with increased motility and stem-like properties via activation of STAT3/Snail axis in atypical teratoid/rhabdoid tumor cells Research Paper

Wei-Hsiu Liu, Ming-Teh Chen, Mong-Lien Wang, Yi-Yen Lee, Guang-Yuh Chiou, Chian-Shiu Chien, Pin-I Huang, Yi-Wei Chen, Ming-Chao Huang, Shih-Hwa Chiou, Yang-Hsin Shih, Hsin-I Ma

Published Jan 31, 2015 · Vol. 6, No. 3 · pp. 1750-1768

Keywords: Atypical teratoid/rhabdoid tumor (ATRT), STAT3, Snail, oncogenic resistance and cisplatin.

miR-874 functions as a tumor suppressor by inhibiting angiogenesis through STAT3/VEGF-A pathway in gastric cancer Research Paper

Xiaoyu Zhang, Jie Tang, Xiaofei Zhi, Kunling Xie, Weizhi Wang, Zheng Li, Yi Zhu, Li Yang, Hao Xu, Zekuan Xu

Published Jan 22, 2015 · Vol. 6, No. 3 · pp. 1605-1617

Keywords: microRNA-874, tumor angiogenesis, STAT3, VEGF-A, gastric cancer

Reciprocal activation between IL-6/STAT3 and NOX4/Akt signalings promotes proliferation and survival of non-small cell lung cancer cells Research Paper

Juan Li, Tian Lan, Cuixiang Zhang, Cheng Zeng, Jincai Hou, Zhicheng Yang, Min Zhang, Jianxun Liu, Bing Liu

Published Jan 8, 2015 · Vol. 6, No. 2 · pp. 1031-1048

Keywords: NOX4, IL-6, non-small cell lung cancer, oxidative stress

ERp57 modulates STAT3 activity in radioresistant laryngeal cancer cells and serves as a prognostic marker for laryngeal cancer Research Paper

Min Ho Choe, Joong Won Min, Hong Bae Jeon, Dong-Hyung Cho, Jeong Su Oh, Hyun Gyu Lee, Sang-Gu Hwang, Sungkwan An, Young-Hoon Han, Jae-Sung Kim

Published Jan 8, 2015 · Vol. 6, No. 5 · pp. 2654-2666

IL-1RT1 signaling antagonizes IL-11 induced STAT3 dependent cardiac and antral stomach tumor development through myeloid cell enrichment Research Paper

Jon N Buzzelli, Dan I Pavlic, Heather V Chalinor, Louise Oâ€™Connor, Trevelyan R Menheniott, Andrew S Giraud, Louise M Judd

Published Jan 6, 2015 · Vol. 6, No. 2 · pp. 679-695

Keywords: Mucosal immunity, cancer immunobiology, cytokines, IL-11, STAT3, IL-1, MDSCs

Acquisition of resistance to trastuzumab in gastric cancer cells is associated with activation of IL-6/STAT3/Jagged-1/Notch positive feedback loop Research Paper

Zhengyan Yang, Liang Guo, Dan Liu, Limin Sun, Hongyu Chen, Que Deng, Yanjun Liu, Ming Yu, Yuanfang Ma, Ning Guo, Ming Shi

Published Dec 31, 2014 · Vol. 6, No. 7 · pp. 5072-5087

Zoledronic acid overcomes chemoresistance and immunosuppression of malignant mesothelioma Research Paper

Iris Chiara Salaroglio, Ivana Campia, Joanna Kopecka, Elena Gazzano, Sara Orecchia, Dario Ghigo, Chiara Riganti

Published Dec 31, 2014 · Vol. 6, No. 2 · pp. 1128-1142

Keywords: malignant mesothelioma, chemoresistance, P-glycoprotein, immunosuppression, indoleamine 1, 2 dioxygenase, zoledronic acid

Novel HDAC inhibitors exhibit pre-clinical efficacy in lymphoma models and point to the importance of CDKN1A expression levels in mediating their anti-tumor response Research Paper

Afua Adjeiwaa Mensah, Ivo Kwee, Eugenio Gaudio, Andrea Rinaldi, Maurilio Ponzoni, Luciano Cascione, Gianluca Fossati, Anastasios Stathis, Emanuele Zucca, Gianluca Caprini, Francesco Bertoni

Published Dec 30, 2014 · Vol. 6, No. 7 · pp. 5059-5071

Expression of the potential therapeutic target CXXC5 in primary acute myeloid leukemia cells - high expression is associated with adverse prognosis as well as altered intracellular signaling and transcriptional regulation Research Paper

Ã˜ystein Bruserud, HÃ¥kon Reikvam, Hanne Fredly, JÃ¸rn Skavland, Karen-Marie Hagen, Tuyen Thy van Hoang, Annette K. Brenner, Amir Kadi, Audrey Astori, BjÃ¸rn Tore Gjertsen, Frederic Pendino

Published Dec 26, 2014 · Vol. 6, No. 5 · pp. 2794-2811

Statin-induced depletion of geranylgeranyl pyrophosphate inhibits cell proliferation by a novel pathway of Skp2 degradation Research Paper

Jonathan Vosper, Alessia Masuccio, Michael Kullmann, Christian Ploner, Stephan Geley, Ludger Hengst

Published Dec 26, 2014 · Vol. 6, No. 5 · pp. 2889-2902

Prostate cancer stem cells: deciphering the origins and pathways involved in prostate tumorigenesis and aggression Review

Adrian P. Rybak, Robert G. Bristow, Anil Kapoor

Published Dec 10, 2014 · Vol. 6, No. 4 · pp. 1900-1919

A novel PI3K inhibitor PIK-C98 displays potent preclinical activity against multiple myeloma Research Paper

Jingyu Zhu, Man Wang, Yang Yu, Huixin Qi, Kunkun Han, Juan Tang, Zubin Zhang, Yuanying Zeng, Biyin Cao, Chunhua Qiao, Hongjian Zhang, Tingjun Hou, Xinliang Mao

Published Dec 2, 2014 · Vol. 6, No. 1 · pp. 185-195

CD147 promotes Src-dependent activation of Rac1 signaling through STAT3/DOCK8 during the motility of hepatocellular carcinoma cells Research Paper

Shi-Jie Wang, Hong-Yong Cui, Yan-Mei Liu, Pu Zhao, Yang Zhang, Zhi-Guang Fu, Zhi-Nan Chen, Jian-Li Jiang

Published Nov 16, 2014 · Vol. 6, No. 1 · pp. 243-257

Sunitinib prevents cachexia and prolongs survival of mice bearing renal cancer by restraining STAT3 and MuRF-1 activation in muscle Research Paper

Francesca Pretto, Carmen Ghilardi, Michele Moschetta, Andrea Bassi, Alessandra Rovida, Valentina Scarlato, Laura Talamini, Fabio Fiordaliso, Cinzia Bisighini, Giovanna Damia, Maria Rosa Bani, Rosanna Piccirillo, Raffaella Giavazzi

Published Nov 15, 2014 · Vol. 6, No. 5 · pp. 3043-3054

Molecular profiling of endometrial carcinoma precursor, primary and metastatic lesions suggests different targets for treatment in obese compared to non-obese patients Clinical Research Papers

Anna Berg, Erling A. Hoivik, Siv MjÃ¸s, Frederik Holst, Henrica M. J. Werner, Ingvild L. Tangen, Amaro Taylor-Weiner, William J. Gibson, Kanthida Kusonmano, Elisabeth Wik, Jone Trovik, Mari K. Halle, Anne M. Ã˜yan, Karl-Henning Kalland, Andrew D. Cherniack, Rameen Beroukhim, Ingunn Stefansson, Gordon B. Mills, Camilla Krakstad, Helga B. Salvesen

Published Nov 4, 2014 · Vol. 6, No. 2 · pp. 1327-1339

STAT3 inhibition suppresses proliferation of retinoblastoma through down-regulation of positive feedback loop of STAT3/miR-17-92 clusters Research Paper

Dong Hyun Jo, Jin Hyoung Kim, Chang Sik Cho, Young-Lai Cho, Hyoung Oh Jun, Young Suk Yu, Jeong-Ki Min, Jeong Hun Kim

Published Nov 3, 2014 · Vol. 5, No. 22 · pp. 11513-11525

Keywords: Retinoblastoma, STAT3 transcription factor, miR-17-92

EBV-driven LMP1 and IFN-Î³ up-regulate PD-L1 in nasopharyngeal carcinoma: Implications for oncotargeted therapy Research Paper

Wenfeng Fang, Jianwei Zhang, Shaodong Hong, Jianhua Zhan, Nan Chen, Tao Qin, Yanna Tang, Yaxiong Zhang, Shiyang Kang, Ting Zhou, Xuan Wu, Wenhua Liang, Zhihuang Hu, Yuxiang Ma, Yuanyuan Zhao, Ying Tian, Yunpeng Yang, Cong Xue, Yue Yan, Xue Hou, Peiyu Huang, Yan Huang, Hongyun Zhao, Li Zhang

Published Oct 21, 2014 · Vol. 5, No. 23 · pp. 12189-12202

Inhibition of STAT5: A therapeutic option in BCR-ABL1-driven leukemia Review

Angelika Berger, Veronika Sexl, Peter Valent, Richard Moriggl

Published Oct 9, 2014 · Vol. 5, No. 20 · pp. 9564-9576

Keywords: STAT5, BCR-ABL1, tyrosine kinase, leukemia, inhibitors, SH2 domain, GTPases, nuclear translocation

Preclinical efficacy of sepantronium bromide (YM155) in multiple myeloma is conferred by down regulation of Mcl-1 Priority Research Paper

Verena Wagner, Dirk Hose, Anja Seckinger, Ludmila Weiz, Tobias MeiÃŸner, Thiery RÃ¨me, Iris Breitkreutz, Klaus Podar, Anthony D. Ho, Hartmut Goldschmidt, Alwin KrÃ¤mer, Bernard Klein, Marc S. Raab

Published Sep 26, 2014 · Vol. 5, No. 21 · pp. 10237-10250

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Brassinin inhibits STAT3 signaling pathway through modulation of PIAS-3 and SOCS-3 expression and sensitizes human lung cancer xenograft in nude mice to paclitaxel Research Paper

Cisplatin-selected resistance is associated with increased motility and stem-like properties via activation of STAT3/Snail axis in atypical teratoid/rhabdoid tumor cells Research Paper

miR-874 functions as a tumor suppressor by inhibiting angiogenesis through STAT3/VEGF-A pathway in gastric cancer Research Paper

Reciprocal activation between IL-6/STAT3 and NOX4/Akt signalings promotes proliferation and survival of non-small cell lung cancer cells Research Paper

ERp57 modulates STAT3 activity in radioresistant laryngeal cancer cells and serves as a prognostic marker for laryngeal cancer Research Paper

IL-1RT1 signaling antagonizes IL-11 induced STAT3 dependent cardiac and antral stomach tumor development through myeloid cell enrichment Research Paper

Acquisition of resistance to trastuzumab in gastric cancer cells is associated with activation of IL-6/STAT3/Jagged-1/Notch positive feedback loop Research Paper

Zoledronic acid overcomes chemoresistance and immunosuppression of malignant mesothelioma Research Paper

Novel HDAC inhibitors exhibit pre-clinical efficacy in lymphoma models and point to the importance of CDKN1A expression levels in mediating their anti-tumor response Research Paper

Expression of the potential therapeutic target CXXC5 in primary acute myeloid leukemia cells - high expression is associated with adverse prognosis as well as altered intracellular signaling and transcriptional regulation Research Paper

Statin-induced depletion of geranylgeranyl pyrophosphate inhibits cell proliferation by a novel pathway of Skp2 degradation Research Paper

Prostate cancer stem cells: deciphering the origins and pathways involved in prostate tumorigenesis and aggression Review

A novel PI3K inhibitor PIK-C98 displays potent preclinical activity against multiple myeloma Research Paper

CD147 promotes Src-dependent activation of Rac1 signaling through STAT3/DOCK8 during the motility of hepatocellular carcinoma cells Research Paper

Sunitinib prevents cachexia and prolongs survival of mice bearing renal cancer by restraining STAT3 and MuRF-1 activation in muscle Research Paper

Molecular profiling of endometrial carcinoma precursor, primary and metastatic lesions suggests different targets for treatment in obese compared to non-obese patients Clinical Research Papers

STAT3 inhibition suppresses proliferation of retinoblastoma through down-regulation of positive feedback loop of STAT3/miR-17-92 clusters Research Paper

EBV-driven LMP1 and IFN-Î³ up-regulate PD-L1 in nasopharyngeal carcinoma: Implications for oncotargeted therapy Research Paper

Inhibition of STAT5: A therapeutic option in BCR-ABL1-driven leukemia Review

Preclinical efficacy of sepantronium bromide (YM155) in multiple myeloma is conferred by down regulation of Mcl-1 Priority Research Paper

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European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Brassinin inhibits STAT3 signaling pathway through modulation of PIAS-3 and SOCS-3 expression and sensitizes human lung cancer xenograft in nude mice to paclitaxel Research Paper

Cisplatin-selected resistance is associated with increased motility and stem-like properties via activation of STAT3/Snail axis in atypical teratoid/rhabdoid tumor cells Research Paper

miR-874 functions as a tumor suppressor by inhibiting angiogenesis through STAT3/VEGF-A pathway in gastric cancer Research Paper

Reciprocal activation between IL-6/STAT3 and NOX4/Akt signalings promotes proliferation and survival of non-small cell lung cancer cells Research Paper

ERp57 modulates STAT3 activity in radioresistant laryngeal cancer cells and serves as a prognostic marker for laryngeal cancer Research Paper

IL-1RT1 signaling antagonizes IL-11 induced STAT3 dependent cardiac and antral stomach tumor development through myeloid cell enrichment Research Paper

Acquisition of resistance to trastuzumab in gastric cancer cells is associated with activation of IL-6/STAT3/Jagged-1/Notch positive feedback loop Research Paper

Zoledronic acid overcomes chemoresistance and immunosuppression of malignant mesothelioma Research Paper

Novel HDAC inhibitors exhibit pre-clinical efficacy in lymphoma models and point to the importance of CDKN1A expression levels in mediating their anti-tumor response Research Paper

Expression of the potential therapeutic target CXXC5 in primary acute myeloid leukemia cells - high expression is associated with adverse prognosis as well as altered intracellular signaling and transcriptional regulation Research Paper

Statin-induced depletion of geranylgeranyl pyrophosphate inhibits cell proliferation by a novel pathway of Skp2 degradation Research Paper

Prostate cancer stem cells: deciphering the origins and pathways involved in prostate tumorigenesis and aggression Review

A novel PI3K inhibitor PIK-C98 displays potent preclinical activity against multiple myeloma Research Paper

CD147 promotes Src-dependent activation of Rac1 signaling through STAT3/DOCK8 during the motility of hepatocellular carcinoma cells Research Paper

Sunitinib prevents cachexia and prolongs survival of mice bearing renal cancer by restraining STAT3 and MuRF-1 activation in muscle Research Paper

Molecular profiling of endometrial carcinoma precursor, primary and metastatic lesions suggests different targets for treatment in obese compared to non-obese patients Clinical Research Papers

STAT3 inhibition suppresses proliferation of retinoblastoma through down-regulation of positive feedback loop of STAT3/miR-17-92 clusters Research Paper

EBV-driven LMP1 and IFN-Î³ up-regulate PD-L1 in nasopharyngeal carcinoma: Implications for oncotargeted therapy Research Paper

Inhibition of STAT5: A therapeutic option in BCR-ABL1-driven leukemia Review

Preclinical efficacy of sepantronium bromide (YM155) in multiple myeloma is conferred by down regulation of Mcl-1 Priority Research Paper