The Oncosearch | Oncotarget

Caffeic acid phenethyl ester induced cell cycle arrest and growth inhibition in androgen-independent prostate cancer cells via regulation of Skp2, p53, p21Cip1 and p27Kip1 Research Paper

Hui-Ping Lin, Ching-Yu Lin, Chieh Huo, Ping-Hsuan Hsiao, Liang-Cheng Su, Shih Sheng Jiang, Tzu-Min Chan, Chung-Ho Chang, Li-Tzong Chen, Hsing-Jien Kung, Horng-Dar Wang, Chih-Pin Chuu

Published Feb 16, 2015 · Vol. 6, No. 9 · pp. 6684-6707

Inhibition of DNA methyltransferase as a novel therapeutic strategy to overcome acquired resistance to dual PI3K/mTOR inhibitors Research Paper

Xiao-jun Qian, Yun-tian Li, Yan Yu, Fen Yang, Rong Deng, Ji Ji, Lin Jiao, Xuan Li, Rui-Yan Wu, Wen-Dan Chen, Gong-Kan Feng, Xiao-Feng Zhu

Published Feb 11, 2015 · Vol. 6, No. 7 · pp. 5134-5146

PKM2 promotes glucose metabolism and cell growth in gliomas through a mechanism involving a let-7a/c-Myc/hnRNPA1 feedback loop Research Paper

Wenkang Luan, Yingyi Wang, Xincheng Chen, Yan Shi, Jiajia Wang, Junxia Zhang, Jin Qian, Ri Li, Tao Tao, Wenjin Wei, Qi Hu, Ning Liu, Yongping You

Published Feb 10, 2015 · Vol. 6, No. 15 · pp. 13006-13018

Distinct anti-oncogenic effect of various microRNAs in different mouse models of liver cancer Research Paper

Junyan Tao, Junfang Ji, Xiaolei Li, Ning Ding, Heng Wu, Yan Liu, XinWei Wang, Diego F. Calvisi, Guisheng Song, Xin Chen

Published Feb 9, 2015 · Vol. 6, No. 9 · pp. 6977-6988

JQ1 suppresses tumor growth through downregulating LDHA in ovarian cancer* Research Paper

Haifeng Qiu, Amanda L. Jackson, Joshua E. Kilgore, Yan Zhong, Leo Li-Ying Chan, Paola A. Gehrig, Chunxiao Zhou, Victoria L. Bae-Jump

Published Feb 5, 2015 · Vol. 6, No. 9 · pp. 6915-6930

Cancerous inhibitor of protein phosphatase 2A contributes to human papillomavirus oncoprotein E7-induced cell proliferation via E2F1 Research Paper

Weifang Zhang, Hanxiang Chen, Yan Chen, Juan Liu, Xiao Wang, Xiuping Yu, Jason J. Chen, Weiming Zhao

Published Feb 4, 2015 · Vol. 6, No. 7 · pp. 5253-5262

Keywords: CIP2A, HPV, E7, G1 arrest, E2F1

Multiple mechanisms of MYCN dysregulation in Wilms tumour Research Paper

Richard D. Williams, Tasnim Chagtai, Marisa Alcaide-German, John Apps, Jenny Wegert, Sergey Popov, Gordan Vujanic, Harm van Tinteren, Marry M. van den Heuvel-Eibrink, Marcel Kool, Jan de Kraker, David Gisselsson, Norbert Graf, Manfred Gessler, Kathy Pritchard-Jones

Published Jan 31, 2015 · Vol. 6, No. 9 · pp. 7232-7243

Flubendazole, FDA-approved anthelmintic, targets breast cancer stem-like cells Research Paper

Zhi-Jie Hou, Xi Luo, Wei Zhang, Fei Peng, Bai Cui, Si-Jin Wu, Fei-Meng Zheng, Jie Xu, Ling-Zhi Xu, Zi-Jie Long, Xue-Ting Wang, Guo-Hui Li, Xian-Yao Wan, Yong-Liang Yang, Quentin Liu

Published Jan 21, 2015 · Vol. 6, No. 8 · pp. 6326-6340

Dysregulated CXCR4 expression promotes lymphoma cell survival and independently predicts disease progression in germinal center B-cell-like diffuse large B-cell lymphoma Research Paper

Jiayu Chen, Zijun Y. Xu-Monette, Lijuan Deng, Qi Shen, Ganiraju C. Manyam, Azahara Martinez-Lopez, Li Zhang, Santiago Montes-Moreno, Carlo Visco, Alexandar Tzankov, Lihui Yin, Karen Dybkaer, April Chiu, Attilio Orazi, Youli Zu, Govind Bhagat, Kristy L. Richards, Eric D. Hsi, William W.L. Choi, J. Han van Krieken, Jooryung Huh, Maurilio Ponzoni, AndrÃ©s J.M. Ferreri, Xiaoying Zhao, Michael B. MÃ¸ller, John P. Farnen, Jane N. Winter, Miguel A. Piris, Lan Pham, Ken H. Young

Published Jan 21, 2015 · Vol. 6, No. 8 · pp. 5597-5614

Mucin1 shifts Smad3 signaling from the tumor-suppressive pSmad3C/p21^WAF1 pathway to the oncogenic pSmad3L/c-Myc pathway by activating JNK in human hepatocellular carcinoma cells Research Paper

Qiongshu Li, Guomu Liu, Hongyan Yuan, Juan Wang, Yingying Guo, Tanxiu Chen, Ruiping Zhai, Dan Shao, Weihua Ni, Guixiang Tai

Published Jan 20, 2015 · Vol. 6, No. 6 · pp. 4253-4265

p19ARF is a critical mediator of both cellular senescence and an innate immune response associated with MYC inactivation in mouse model of acute leukemia Priority Research Paper

Alper Yetil, Benedict Anchang, Arvin M. Gouw, Stacey J. Adam, Tahera Zabuawala, Ramya Parameswaran, Jan van Riggelen, Sylvia Plevritis, Dean W. Felsher

Published Jan 13, 2015 · Vol. 6, No. 6 · pp. 3563-3577

miR-34a induces cellular senescence via modulation of telomerase activity in human hepatocellular carcinoma by targeting FoxM1/c-Myc pathway Research Paper

Xinsen Xu, Wei Chen, Runchen Miao, Yanyan Zhou, Zhixin Wang, Lingqiang Zhang, Yong Wan, Yafeng Dong, Kai Qu, Chang Liu

Published Jan 9, 2015 · Vol. 6, No. 6 · pp. 3988-4004

Cyclosporine A and tacrolimus inhibit bladder cancer growth through down-regulation of NFATc1 Research Paper

Takashi Kawahara, Eiji Kashiwagi, Hiroki Ide, Yi Li, Yichun Zheng, Yurina Miyamoto, George J. Netto, Hitoshi Ishiguro, Hiroshi Miyamoto

Published Jan 8, 2015 · Vol. 6, No. 3 · pp. 1582-1593

Keywords: bladder cancer, cyclosporine, NFAT, tacrolimus, tumor progression

Constitutive activation of the DNA damage response pathway as a novel therapeutic target in diffuse large B-cell lymphoma Research Paper

Enrico Derenzini, Claudio Agostinelli, Enrica Imbrogno, Ilaria Iacobucci, Beatrice Casadei, Elisa Brighenti, Simona Righi, Fabio Fuligni, Andrea Ghelli Luserna Di RorÃ, Anna Ferrari, Giovanni Martinelli, Stefano Pileri, Pier Luigi Zinzani

Published Jan 7, 2015 · Vol. 6, No. 9 · pp. 6553-6569

Keywords: Diffuse Large B-cell Lymphoma, genomic instability, CHK1, CHK2, gamma-H2AX, MYC

Haploinsufficiency of the c-myc transcriptional repressor FIR, as a dominant negative-alternative splicing model, promoted p53-dependent T-cell acute lymphoblastic leukemia progression by activating Notch1 Research Paper

Kazuyuki Matsushita, Kouichi Kitamura, Bahityar Rahmutulla, Nobuko Tanaka, Takayuki Ishige, Mamoru Satoh, Tyuji Hoshino, Satoru Miyagi, Takeshi Mori, Sakae Itoga, Hideaki Shimada, Takeshi Tomonaga, Minoru Kito, Yaeko Nakajima-Takagi, Shuji Kubo, Chiaki Nakaseko, Masahiko Hatano, Takashi Miki, Masafumi Matsuo, Masaki Fukuyo, Atsushi Kaneda, Atsushi Iwama, Fumio Nomura

Published Dec 31, 2014 · Vol. 6, No. 7 · pp. 5102-5117

MicroRNA-130a associates with ribosomal protein L11 to suppress c-Myc expression in response to UV irradiation Research Paper

Yuhuang Li, Kishore B Challagundla, Xiao-Xin Sun, Qinghong Zhang, Mu-Shui Dai

Published Dec 31, 2014 · Vol. 6, No. 2 · pp. 1101-1114

Keywords: miR-130a, ribosomal protein, L11, c-Myc, microRNA, miRISC, UV irradiation.

Mechanism of action and therapeutic efficacy of Aurora kinase B inhibition in MYC overexpressing medulloblastoma Research Paper

Roberto Jose Diaz, Brian Golbourn, Claudia Faria, Daniel Picard, David Shih, Denis Raynaud, Michael Leadly, Danielle MacKenzie, Melissa Bryant, Matthew Bebenek, Christian A. Smith, Michael D. Taylor, Annie Huang, James T. Rutka

Published Dec 31, 2014 · Vol. 6, No. 5 · pp. 3359-3374

Novel oral histone deacetylase inhibitor, MPT0E028, displays potent growth-inhibitory activity against human B-cell lymphoma in vitro and in vivo Research Paper

Han-Li Huang, Chieh-Yu Peng, Mei-Jung Lai, Chun-Han Chen, Hsueh-Yun Lee, Jing-Chi Wang, Jing-Ping Liou, Shiow-Lin Pan, Che-Ming Teng

Published Dec 31, 2014 · Vol. 6, No. 7 · pp. 4976-4991

Advances in dynamic modeling of colorectal cancer signaling-network regions, a path toward targeted therapies Research Paper

Lorenzo Tortolina, David J. Duffy, Massimo Maffei, Nicoletta Castagnino, AimÃ©e M. Carmody, Walter Kolch, Boris N. Kholodenko, Cristina De Ambrosi, Annalisa Barla, Elia M. Biganzoli, Alessio Nencioni, Franco Patrone, Alberto Ballestrero, Gabriele Zoppoli, Alessandro Verri, Silvio Parodi

Published Dec 31, 2014 · Vol. 6, No. 7 · pp. 5041-5058

MYC regulates the non-coding transcriptome Priority Research Paper

Jonathan R. Hart, Thomas C. Roberts, Marc S. Weinberg, Kevin V. Morris, Peter K. Vogt

Published Dec 30, 2014 · Vol. 5, No. 24 · pp. 12543-12554

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Caffeic acid phenethyl ester induced cell cycle arrest and growth inhibition in androgen-independent prostate cancer cells via regulation of Skp2, p53, p21Cip1 and p27Kip1 Research Paper

Inhibition of DNA methyltransferase as a novel therapeutic strategy to overcome acquired resistance to dual PI3K/mTOR inhibitors Research Paper

PKM2 promotes glucose metabolism and cell growth in gliomas through a mechanism involving a let-7a/c-Myc/hnRNPA1 feedback loop Research Paper

Distinct anti-oncogenic effect of various microRNAs in different mouse models of liver cancer Research Paper

JQ1 suppresses tumor growth through downregulating LDHA in ovarian cancer* Research Paper

Cancerous inhibitor of protein phosphatase 2A contributes to human papillomavirus oncoprotein E7-induced cell proliferation via E2F1 Research Paper

Multiple mechanisms of MYCN dysregulation in Wilms tumour Research Paper

Flubendazole, FDA-approved anthelmintic, targets breast cancer stem-like cells Research Paper

Dysregulated CXCR4 expression promotes lymphoma cell survival and independently predicts disease progression in germinal center B-cell-like diffuse large B-cell lymphoma Research Paper

Mucin1 shifts Smad3 signaling from the tumor-suppressive pSmad3C/p21^WAF1 pathway to the oncogenic pSmad3L/c-Myc pathway by activating JNK in human hepatocellular carcinoma cells Research Paper

p19ARF is a critical mediator of both cellular senescence and an innate immune response associated with MYC inactivation in mouse model of acute leukemia Priority Research Paper

miR-34a induces cellular senescence via modulation of telomerase activity in human hepatocellular carcinoma by targeting FoxM1/c-Myc pathway Research Paper

Cyclosporine A and tacrolimus inhibit bladder cancer growth through down-regulation of NFATc1 Research Paper

Constitutive activation of the DNA damage response pathway as a novel therapeutic target in diffuse large B-cell lymphoma Research Paper

Haploinsufficiency of the c-myc transcriptional repressor FIR, as a dominant negative-alternative splicing model, promoted p53-dependent T-cell acute lymphoblastic leukemia progression by activating Notch1 Research Paper

MicroRNA-130a associates with ribosomal protein L11 to suppress c-Myc expression in response to UV irradiation Research Paper

Mechanism of action and therapeutic efficacy of Aurora kinase B inhibition in MYC overexpressing medulloblastoma Research Paper

Novel oral histone deacetylase inhibitor, MPT0E028, displays potent growth-inhibitory activity against human B-cell lymphoma in vitro and in vivo Research Paper

Advances in dynamic modeling of colorectal cancer signaling-network regions, a path toward targeted therapies Research Paper

MYC regulates the non-coding transcriptome Priority Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Caffeic acid phenethyl ester induced cell cycle arrest and growth inhibition in androgen-independent prostate cancer cells via regulation of Skp2, p53, p21Cip1 and p27Kip1 Research Paper

Inhibition of DNA methyltransferase as a novel therapeutic strategy to overcome acquired resistance to dual PI3K/mTOR inhibitors Research Paper

PKM2 promotes glucose metabolism and cell growth in gliomas through a mechanism involving a let-7a/c-Myc/hnRNPA1 feedback loop Research Paper

Distinct anti-oncogenic effect of various microRNAs in different mouse models of liver cancer Research Paper

JQ1 suppresses tumor growth through downregulating LDHA in ovarian cancer* Research Paper

Cancerous inhibitor of protein phosphatase 2A contributes to human papillomavirus oncoprotein E7-induced cell proliferation via E2F1 Research Paper

Multiple mechanisms of MYCN dysregulation in Wilms tumour Research Paper

Flubendazole, FDA-approved anthelmintic, targets breast cancer stem-like cells Research Paper

Dysregulated CXCR4 expression promotes lymphoma cell survival and independently predicts disease progression in germinal center B-cell-like diffuse large B-cell lymphoma Research Paper

Mucin1 shifts Smad3 signaling from the tumor-suppressive pSmad3C/p21WAF1 pathway to the oncogenic pSmad3L/c-Myc pathway by activating JNK in human hepatocellular carcinoma cells Research Paper

p19ARF is a critical mediator of both cellular senescence and an innate immune response associated with MYC inactivation in mouse model of acute leukemia Priority Research Paper

miR-34a induces cellular senescence via modulation of telomerase activity in human hepatocellular carcinoma by targeting FoxM1/c-Myc pathway Research Paper

Cyclosporine A and tacrolimus inhibit bladder cancer growth through down-regulation of NFATc1 Research Paper

Constitutive activation of the DNA damage response pathway as a novel therapeutic target in diffuse large B-cell lymphoma Research Paper

Haploinsufficiency of the c-myc transcriptional repressor FIR, as a dominant negative-alternative splicing model, promoted p53-dependent T-cell acute lymphoblastic leukemia progression by activating Notch1 Research Paper

MicroRNA-130a associates with ribosomal protein L11 to suppress c-Myc expression in response to UV irradiation Research Paper

Mechanism of action and therapeutic efficacy of Aurora kinase B inhibition in MYC overexpressing medulloblastoma Research Paper

Novel oral histone deacetylase inhibitor, MPT0E028, displays potent growth-inhibitory activity against human B-cell lymphoma in vitro and in vivo Research Paper

Advances in dynamic modeling of colorectal cancer signaling-network regions, a path toward targeted therapies Research Paper

MYC regulates the non-coding transcriptome Priority Research Paper

Mucin1 shifts Smad3 signaling from the tumor-suppressive pSmad3C/p21^WAF1 pathway to the oncogenic pSmad3L/c-Myc pathway by activating JNK in human hepatocellular carcinoma cells Research Paper