The Oncosearch | Oncotarget

Current perspectives between metabolic syndrome and cancer Review

Carla Micucci, Debora Valli, Giulia Matacchione, Alfonso Catalano

Published Mar 24, 2016 · Vol. 7, No. 25 · pp. 38959-38972

mTOR complex-2 stimulates acetyl-CoA and de novo lipogenesis through ATP citrate lyase in HER2/PIK3CA-hyperactive breast cancer Research Paper

Yaqing Chen, Jianchang Qian, Qun He, Hui Zhao, Lourdes Toral-Barza, Celine Shi, Xuesai Zhang, Jiang Wu, Ker Yu

Published Mar 22, 2016 · Vol. 7, No. 18 · pp. 25224-25240

The effects of graded levels of calorie restriction: V. Impact of short term calorie and protein restriction on physical activity in the C57BL/6 mouse Research Paper

Sharon E. Mitchell, Camille Delville, Penelope Konstantopedos, Davina Derous, Cara L. Green, Yingchun Wang, Jing-Dong J. Han, Daniel E.L. Promislow, Alex Douglas, Luonan Chen, David Lusseau, John R. Speakman

Published Mar 17, 2016 · Vol. 7, No. 15 · pp. 19147-19170

Protein kinase C beta II suppresses colorectal cancer by regulating IGF-1 mediated cell survival Research Paper

CatrÃona M. Dowling, James Phelan, Julia A. Callender, Mary Clare Cathcart, Brian Mehigan, Paul McCormick, Tara Dalton, John C. Coffey, Alexandra C. Newton, Jacintha Oâ€™Sullivan, Patrick A. Kiely

Published Mar 14, 2016 · Vol. 7, No. 15 · pp. 20919-20933

Activation of the IGF1R pathway potentially mediates acquired resistance to mutant-selective 3rd-generation EGF receptor tyrosine kinase inhibitors in advanced non-small cell lung cancer Research Paper

Ji Hyun Park, Yun Jung Choi, Seon Ye Kim, Jung-Eun Lee, Ki Jung Sung, Sojung Park, Woo Sung Kim, Joon Seon Song, Chang-Min Choi, Young Hoon Sung, Jin Kyung Rho, Jae Cheol Lee

Published Mar 9, 2016 · Vol. 7, No. 16 · pp. 22005-22015

Insulin receptor substrate 1 is a substrate of the Pim protein kinases Research Paper

Jin H. Song, Sathish K. R. Padi, Libia A. Luevano, Mark D. Minden, Daniel J. DeAngelo, Gary Hardiman, Lauren E. Ball, Noel A. Warfel, Andrew S. Kraft

Published Mar 4, 2016 · Vol. 7, No. 15 · pp. 20152-20165

A BRCA1 deficient, NFÎºB driven immune signal predicts good outcome in triple negative breast cancer Research Paper

Niamh E. Buckley, Paula Haddock, Ricardo De Matos Simoes, Eileen Parkes, Gareth Irwin, Frank Emmert-Streib, Stephen McQuaid, Richard Kennedy, Paul Mullan

Published Mar 2, 2016 · Vol. 7, No. 15 · pp. 19884-19896

Targeting the insulin growth factor-1 receptor with fluorescent antibodies enables high resolution imaging of human pancreatic cancer in orthotopic mouse models Research Paper

Jeong Youp Park, Jin Young Lee, Yong Zhang, Robert M. Hoffman, Michael Bouvet

Published Feb 22, 2016 · Vol. 7, No. 14 · pp. 18262-18268

IMP1 suppresses breast tumor growth and metastasis through the regulation of its target mRNAs Research Paper

Guangli Wang, Zhenqiang Huang, Xin Liu, Wenhe Huang, Shaoying Chen, Yanchun Zhou, Deling Li, Robert H. Singer, Wei Gu

Published Feb 17, 2016 · Vol. 7, No. 13 · pp. 15690-15702

MLN-8237: A dual inhibitor of aurora A and B in soft tissue sarcomas Research Paper

Jayasree S. Nair, Gary K. Schwartz

Published Feb 12, 2016 · Vol. 7, No. 11 · pp. 12893-12903

Longitudinal tracking of subpopulation dynamics and molecular changes during LNCaP cell castration and identification of inhibitors that could target the PSAâˆ’/lo castration-resistant cells Research Paper

Kiera Rycaj, Eun Jeong Cho, Xin Liu, Hsueh-Ping Chao, Bigang Liu, Qiuhui Li, Ashwini K. Devkota, Dingxiao Zhang, Xin Chen, John Moore, Kevin N. Dalby, Dean G. Tang

Published Feb 10, 2016 · Vol. 7, No. 12 · pp. 14220-14240

Hyperinsulinemia enhances interleukin-17-induced inflammation to promote prostate cancer development in obese mice through inhibiting glycogen synthase kinase 3-mediated phosphorylation and degradation of interleukin-17 receptor Research Paper

Sen Liu, Qiuyang Zhang, Chong Chen, Dongxia Ge, Yine Qu, Rongyi Chen, Yi-Ming Fan, Nan Li, Wendell W. Tang, Wensheng Zhang, Kun Zhang, Alun R. Wang, Brian G. Rowan, Steven M. Hill, Oliver Sartor, Asim B. Abdel-Mageed, Leann Myers, Qishan Lin, Zongbing You

Published Feb 10, 2016 · Vol. 7, No. 12 · pp. 13651-13666

The dual targeting of insulin and insulin-like growth factor 1 receptor enhances the mTOR inhibitor-mediated antitumor efficacy in hepatocellular carcinoma Research Paper

Claudia Pivonello, Mariarosaria Negri, Maria Cristina De Martino, Maria Napolitano, Cristina de Angelis, Donatella Paola Provvisiero, Gaia Cuomo, Renata Simona Auriemma, Chiara Simeoli, Francesco Izzo, Annamaria Colao, Leo J. Hofland, Rosario Pivonello

Published Jan 7, 2016 · Vol. 7, No. 9 · pp. 9718-9731

Association study of polymorphisms in FOXO3, AKT1 and IGF-2R genes with human longevity in a Han Chinese population Research Paper

Ning Li, Huaichao Luo, Xiaoqi Liu, Shi Ma, He Lin, Rong Chen, Fang Hao, Dingding Zhang

Published Dec 16, 2015 · Vol. 7, No. 1 · pp. 23-32

Significant blockade of multiple receptor tyrosine kinases by MGCD516 (Sitravatinib), a novel small molecule inhibitor, shows potent anti-tumor activity in preclinical models of sarcoma Research Paper

Parag P. Patwardhan, Kathryn S. Ivy, Elgilda Musi, Elisa de Stanchina, Gary K. Schwartz

Published Dec 10, 2015 · Vol. 7, No. 4 · pp. 4093-4109

IGF-I induces upregulation of DDR1 collagen receptor in breast cancer cells by suppressing MIR-199a-5p through the PI3K/AKT pathway Research Paper

Roberta MatÃ, Chiara Palladino, Maria Luisa Nicolosi, Anna Rita Lo Presti, Roberta Malaguarnera, Marco Ragusa, Daniela Sciortino, Andrea Morrione, Marcello Maggiolini, Veronica Vella, Antonino Belfiore

Published Dec 9, 2015 · Vol. 7, No. 7 · pp. 7683-7700

Unique roles of Akt1 and Akt2 in IGF-IR mediated lung tumorigenesis Research Paper

Elizabeth S. Franks, Ritesh Briah, Robert A. Jones, Roger A. Moorehead

Published Dec 7, 2015 · Vol. 7, No. 3 · pp. 3297-3316

Genomic landscape of liposarcoma Priority Research Paper

Deepika Kanojia, Yasunobu Nagata, Manoj Garg, Dhong Hyun Lee, Aiko Sato, Kenichi Yoshida, Yusuke Sato, Masashi Sanada, Anand Mayakonda, Christoph Bartenhagen, Hans-Ulrich Klein, Ngan B. Doan, Jonathan W. Said, S. Mohith, Swetha Gunasekar, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Satoru Miyano, Ola Myklebost, Henry Yang, Martin Dugas, Leonardo A. Meza-Zepeda, Allan W. Silberman, Charles Forscher, Jeffrey W. Tyner, Seishi Ogawa, H. Phillip Koeffler

Published Dec 4, 2015 · Vol. 6, No. 40 · pp. 42429-42444

The erbB3- and IGF-1 receptor-initiated signaling pathways exhibit distinct effects on lapatinib sensitivity against trastuzumab-resistant breast cancer cells Research Paper

Hui Lyu, XiaoHe Yang, Susan M. Edgerton, Ann D. Thor, Xiaoying Wu, Zhimin He, Bolin Liu

Published Nov 26, 2015 · Vol. 7, No. 3 · pp. 2921-2935

Infiltrating T cells promote renal cell carcinoma (RCC) progression via altering the estrogen receptor β-DAB2IP signals Research Paper

Chiuan-Ren Yeh, Zheng-Yu Ou, Guang-Qian Xiao, Elizabeth Guancial, Shuyuan Yeh

Published Nov 17, 2015 · Vol. 6, No. 42 · pp. 44346-44359

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Current perspectives between metabolic syndrome and cancer Review

mTOR complex-2 stimulates acetyl-CoA and de novo lipogenesis through ATP citrate lyase in HER2/PIK3CA-hyperactive breast cancer Research Paper

The effects of graded levels of calorie restriction: V. Impact of short term calorie and protein restriction on physical activity in the C57BL/6 mouse Research Paper

Protein kinase C beta II suppresses colorectal cancer by regulating IGF-1 mediated cell survival Research Paper

Activation of the IGF1R pathway potentially mediates acquired resistance to mutant-selective 3rd-generation EGF receptor tyrosine kinase inhibitors in advanced non-small cell lung cancer Research Paper

Insulin receptor substrate 1 is a substrate of the Pim protein kinases Research Paper

A BRCA1 deficient, NFÎºB driven immune signal predicts good outcome in triple negative breast cancer Research Paper

Targeting the insulin growth factor-1 receptor with fluorescent antibodies enables high resolution imaging of human pancreatic cancer in orthotopic mouse models Research Paper

IMP1 suppresses breast tumor growth and metastasis through the regulation of its target mRNAs Research Paper

MLN-8237: A dual inhibitor of aurora A and B in soft tissue sarcomas Research Paper

Longitudinal tracking of subpopulation dynamics and molecular changes during LNCaP cell castration and identification of inhibitors that could target the PSAâˆ’/lo castration-resistant cells Research Paper

Hyperinsulinemia enhances interleukin-17-induced inflammation to promote prostate cancer development in obese mice through inhibiting glycogen synthase kinase 3-mediated phosphorylation and degradation of interleukin-17 receptor Research Paper

The dual targeting of insulin and insulin-like growth factor 1 receptor enhances the mTOR inhibitor-mediated antitumor efficacy in hepatocellular carcinoma Research Paper

Association study of polymorphisms in FOXO3, AKT1 and IGF-2R genes with human longevity in a Han Chinese population Research Paper

Significant blockade of multiple receptor tyrosine kinases by MGCD516 (Sitravatinib), a novel small molecule inhibitor, shows potent anti-tumor activity in preclinical models of sarcoma Research Paper

IGF-I induces upregulation of DDR1 collagen receptor in breast cancer cells by suppressing MIR-199a-5p through the PI3K/AKT pathway Research Paper

Unique roles of Akt1 and Akt2 in IGF-IR mediated lung tumorigenesis Research Paper

Genomic landscape of liposarcoma Priority Research Paper

The erbB3- and IGF-1 receptor-initiated signaling pathways exhibit distinct effects on lapatinib sensitivity against trastuzumab-resistant breast cancer cells Research Paper

Infiltrating T cells promote renal cell carcinoma (RCC) progression via altering the estrogen receptor β-DAB2IP signals Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Current perspectives between metabolic syndrome and cancer Review

mTOR complex-2 stimulates acetyl-CoA and de novo lipogenesis through ATP citrate lyase in HER2/PIK3CA-hyperactive breast cancer Research Paper

The effects of graded levels of calorie restriction: V. Impact of short term calorie and protein restriction on physical activity in the C57BL/6 mouse Research Paper

Protein kinase C beta II suppresses colorectal cancer by regulating IGF-1 mediated cell survival Research Paper

Activation of the IGF1R pathway potentially mediates acquired resistance to mutant-selective 3rd-generation EGF receptor tyrosine kinase inhibitors in advanced non-small cell lung cancer Research Paper

Insulin receptor substrate 1 is a substrate of the Pim protein kinases Research Paper

A BRCA1 deficient, NFÎºB driven immune signal predicts good outcome in triple negative breast cancer Research Paper

Targeting the insulin growth factor-1 receptor with fluorescent antibodies enables high resolution imaging of human pancreatic cancer in orthotopic mouse models Research Paper

IMP1 suppresses breast tumor growth and metastasis through the regulation of its target mRNAs Research Paper

MLN-8237: A dual inhibitor of aurora A and B in soft tissue sarcomas Research Paper

Longitudinal tracking of subpopulation dynamics and molecular changes during LNCaP cell castration and identification of inhibitors that could target the PSAâˆ’/lo castration-resistant cells Research Paper

Hyperinsulinemia enhances interleukin-17-induced inflammation to promote prostate cancer development in obese mice through inhibiting glycogen synthase kinase 3-mediated phosphorylation and degradation of interleukin-17 receptor Research Paper

The dual targeting of insulin and insulin-like growth factor 1 receptor enhances the mTOR inhibitor-mediated antitumor efficacy in hepatocellular carcinoma Research Paper

Association study of polymorphisms in FOXO3, AKT1 and IGF-2R genes with human longevity in a Han Chinese population Research Paper

Significant blockade of multiple receptor tyrosine kinases by MGCD516 (Sitravatinib), a novel small molecule inhibitor, shows potent anti-tumor activity in preclinical models of sarcoma Research Paper

IGF-I induces upregulation of DDR1 collagen receptor in breast cancer cells by suppressing MIR-199a-5p through the PI3K/AKT pathway Research Paper

Unique roles of Akt1 and Akt2 in IGF-IR mediated lung tumorigenesis Research Paper

Genomic landscape of liposarcoma Priority Research Paper

The erbB3- and IGF-1 receptor-initiated signaling pathways exhibit distinct effects on lapatinib sensitivity against trastuzumab-resistant breast cancer cells Research Paper

Infiltrating T cells promote renal cell carcinoma (RCC) progression via altering the estrogen receptor β-DAB2IP signals Research Paper