The Oncosearch | Oncotarget

Hepatitis B virus X protein induces expression of alpha-fetoprotein and activates PI3K/mTOR signaling pathway in liver cells Research Paper

Mingyue Zhu, Junli Guo, Wei Li, Yan Lu, Shigan Fu, Xieju Xie, Hua Xia, Xu Dong, Yi Chen, Ming Quan, Shaojiang Zheng, Keping Xie, Mengsen Li

Published Jan 21, 2015 · Vol. 6, No. 14 · pp. 12196-12208

Induction of cellular prion protein (PrPc) under hypoxia inhibits apoptosis caused by TRAIL treatment Research Paper

Jin-Young Park, Jae-Kyo Jeong, Ju-Hee Lee, Ji-Hong Moon, Sung-Wook Kim, You-Jin Lee, Sang-Youel Park

Published Jan 20, 2015 · Vol. 6, No. 7 · pp. 5342-5353

Zoledronic acid overcomes chemoresistance and immunosuppression of malignant mesothelioma Research Paper

Iris Chiara Salaroglio, Ivana Campia, Joanna Kopecka, Elena Gazzano, Sara Orecchia, Dario Ghigo, Chiara Riganti

Published Dec 31, 2014 · Vol. 6, No. 2 · pp. 1128-1142

Keywords: malignant mesothelioma, chemoresistance, P-glycoprotein, immunosuppression, indoleamine 1, 2 dioxygenase, zoledronic acid

Ferroxitosis: A cell death from modulation of oxidative phosphorylation and PKM2-dependent glycolysis in melanoma Research Paper

Alexander J. Lakhter, James Hamilton, Pierre C. Dagher, Suresh Mukkamala, Takashi Hato, X. Charlie Dong, Lindsey D. Mayo, Robert A. Harris, Anantha Shekhar, Mircea Ivan, Nickolay Brustovetsky, Samisubbu R. Naidu

Published Dec 26, 2014 · Vol. 5, No. 24 · pp. 12694-12703

Hypoxia-inducible factor 1 mediates TAZ expression and nuclear localization to induce the breast cancer stem cell phenotype Priority Research Paper

Lisha Xiang, Daniele M. Gilkes, Hongxia Hu, Naoharu Takano, Weibo Luo, Haiquan Lu, John W. Bullen, Debangshu Samanta, Houjie Liang, Gregg L. Semenza

Published Dec 18, 2014 · Vol. 5, No. 24 · pp. 12509-12527

Hypoxia induces a lipogenic cancer cell phenotype via HIF1Î±-dependent and -independent pathways Priority Research Paper

Alessandro Valli, Miguel Rodriguez, Loukas Moutsianas, Roman Fischer, Vita Fedele, Hong-Lei Huang, Ruud Van Stiphout, Dylan Jones, Michael Mccarthy, Maria Vinaxia, Kaori Igarashi, Maya Sato, Tomoyoshi Soga, Francesca Buffa, James Mccullagh, Oscar Yanes, Adrian Harris, Benedikt Kessler

Published Dec 11, 2014 · Vol. 6, No. 4 · pp. 1920-1941

Hypoxia up-regulates SERPINB3 through HIF-2Î± in human liver cancer cells Research Paper

Stefania Cannito, Cristian Turato, Claudia Paternostro, Alessandra Biasiolo, Sebastiano Colombatto, Irene Cambieri, Santina Quarta, Erica Novo, Elisabetta Morello, Gianmarco Villano, Silvano Fasolato, Tiziana Musso, Ezio David, Ignazia Tusa, Elisabetta Rovida, Riccardo Autelli, Antonina Smedile, Umberto Cillo, Patrizia Pontisso, Maurizio Parola

Published Dec 10, 2014 · Vol. 6, No. 4 · pp. 2206-2221

Inhibition of HIF-1Î± by PX-478 enhances the anti-tumor effect of gemcitabine by inducing immunogenic cell death in pancreatic ductal adenocarcinoma Research Paper

Tiansuo Zhao, He Ren, Li Jia, Jing Chen, Wen Xin, Fan Yan, Jing Li, Xiuchao Wang, Song Gao, Dong Qian, Chongbiao Huang, Jihui Hao

Published Dec 10, 2014 · Vol. 6, No. 4 · pp. 2250-2262

Î³-H2AX promotes hepatocellular carcinoma angiogenesis via EGFR/HIF-1Î±/VEGF pathways under hypoxic condition Research Paper

Heng Xiao, Rongliang Tong, Chaofeng Ding, Zhen Lv, Chengli Du, Chuanhui Peng, Shaobing Cheng, Haiyang Xie, Lin Zhou, Jian Wu, Shusen Zheng

Published Dec 10, 2014 · Vol. 6, No. 4 · pp. 2180-2192

Hypoxia-inducible factor 1 alpha is regulated by RBM38, a RNA-binding protein and a p53 family target, via mRNA translation Research Paper

Seong-Jun Cho, I-Fang Teng, Min Zhang, Tiffany Yin, Yong-Sam Jung, Jin Zhang, Xinbin Chen

Published Nov 16, 2014 · Vol. 6, No. 1 · pp. 305-316

Inhibition of succinate dehydrogenase by the mitochondrial chaperone TRAP1 has anti-oxidant and anti-apoptotic effects on tumor cells Research Paper

Giulia Guzzo, Marco Sciacovelli, Paolo Bernardi, Andrea Rasola

Published Nov 15, 2014 · Vol. 5, No. 23 · pp. 11897-11908

Keywords: TRAP1, mitochondria, chaperones, cancer metabolism, ROS, succinate dehydrogenase

Targeting hypoxia-inducible factor-1Î± (HIF-1Î±) in combination with antiangiogenic therapy: A phase I trial of bortezomib plus bevacizumab Clinical Research Papers

Gerald S. Falchook, Jennifer J. Wheler, Aung Naing, Edward F. Jackson, Filip Janku, David Hong, Chaan S. Ng, Nizar M. Tannir, Kristie N. Lawhorn, Mei Huang, Laura S. Angelo, Deeksha Vishwamitra, Kenneth Hess, Adrienne N. Howard, Kristin L. Parkhurst, Hesham M. Amin, Razelle Kurzrock

Published Nov 8, 2014 · Vol. 5, No. 21 · pp. 10280-10292

Syringaresinol protects against hypoxia/reoxygenation-induced cardiomyocytes injury and death by destabilization of HIF-1Î± in a FOXO3-dependent mechanism Priority Research Paper

Siyoung Cho, Miook Cho, Juewon Kim, Matt Kaeberlein, Sang Jun Lee, Yousin Suh

Published Nov 6, 2014 · Vol. 6, No. 1 · pp. 43-55

Heptamethine carbocyanine dye-mediated near-infrared imaging of canine and human cancers through the HIF-1Î±/OATPs signaling axis Research Paper

Changhong Shi, Jason Boyang Wu, Gina C-Y. Chu, Qinlong Li, Ruoxiang Wang, Caiqin Zhang, Yi Zhang, Hyung L. Kim, Haiyen E. Zhau, Dongfeng Pan, Leland W.K. Chung

Published Oct 25, 2014 · Vol. 5, No. 20 · pp. 10114-10126

Phospholipase D1 protein coordinates dynamic assembly of HIF-1Î±-PHD-VHL to regulate HIF-1Î± stability Research Paper

Mi Hee Park, Kang-Yell Choi, Yunjin Jung, Do Sik Min

Published Oct 21, 2014 · Vol. 5, No. 23 · pp. 11857-11872

Chemopreventive apigenin controls UVB-induced cutaneous proliferation and angiogenesis through HuR and thrombospondin-1 Research Paper

Xin Tong, Salida Mirzoeva, Dorina Veliceasa, Bryan B. Bridgeman, Philip Fitchev, Mona L. Cornwell, Susan E. Crawford, Jill C. Pelling, Olga V. Volpert

Published Oct 15, 2014 · Vol. 5, No. 22 · pp. 11413-11427

Hypoxia-inducible factors enhance glutamate signaling in cancer cells Priority Research Paper

Hongxia Hu, Naoharu Takano, Lisha Xiang, Daniele M. Gilkes, Weibo Luo, Gregg L. Semenza

Published Oct 15, 2014 · Vol. 5, No. 19 · pp. 8853-8868

HS-133, a novel fluorescent phosphatidylinositol 3-kinase inhibitor as a potential imaging and anticancer agent for targeted therapy Research Paper

Ju-Hee Lee, Kyung Hee Jung, Hyunseung Lee, Mi Kwon Son, Sun-Mi Yun, Sung-Hoon Ahn, Kyeong-Ryoon Lee, Soyoung Lee, Donghee Kim, Sungwoo Hong, Soon-Sun Hong

Published Sep 29, 2014 · Vol. 5, No. 20 · pp. 10180-10197

MiR-578 and miR-573 as potential players in BRCA-related breast cancer angiogenesis Research Paper

Katia Danza, Simona De Summa, Rosamaria Pinto, Brunella Pilato, Orazio Palumbo, Giuseppe Merla, Gianni Simone, Stefania Tommasi

Published Sep 25, 2014 · Vol. 6, No. 1 · pp. 471-483

P2Y₂R activation by nucleotides released from the highly metastatic breast cancer cell contributes to pre-metastatic niche formation by mediating lysyl oxidase secretion, collagen crosslinking, and monocyte recruitment Research Paper

Young Nak Joo, Hana Jin, So Young Eun, Sang Won Park, Ki Churl Chang, Hye Jung Kim

Published Sep 2, 2014 · Vol. 5, No. 19 · pp. 9322-9334

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Hepatitis B virus X protein induces expression of alpha-fetoprotein and activates PI3K/mTOR signaling pathway in liver cells Research Paper

Induction of cellular prion protein (PrPc) under hypoxia inhibits apoptosis caused by TRAIL treatment Research Paper

Zoledronic acid overcomes chemoresistance and immunosuppression of malignant mesothelioma Research Paper

Ferroxitosis: A cell death from modulation of oxidative phosphorylation and PKM2-dependent glycolysis in melanoma Research Paper

Hypoxia-inducible factor 1 mediates TAZ expression and nuclear localization to induce the breast cancer stem cell phenotype Priority Research Paper

Hypoxia induces a lipogenic cancer cell phenotype via HIF1Î±-dependent and -independent pathways Priority Research Paper

Hypoxia up-regulates SERPINB3 through HIF-2Î± in human liver cancer cells Research Paper

Inhibition of HIF-1Î± by PX-478 enhances the anti-tumor effect of gemcitabine by inducing immunogenic cell death in pancreatic ductal adenocarcinoma Research Paper

Î³-H2AX promotes hepatocellular carcinoma angiogenesis via EGFR/HIF-1Î±/VEGF pathways under hypoxic condition Research Paper

Hypoxia-inducible factor 1 alpha is regulated by RBM38, a RNA-binding protein and a p53 family target, via mRNA translation Research Paper

Inhibition of succinate dehydrogenase by the mitochondrial chaperone TRAP1 has anti-oxidant and anti-apoptotic effects on tumor cells Research Paper

Targeting hypoxia-inducible factor-1Î± (HIF-1Î±) in combination with antiangiogenic therapy: A phase I trial of bortezomib plus bevacizumab Clinical Research Papers

Syringaresinol protects against hypoxia/reoxygenation-induced cardiomyocytes injury and death by destabilization of HIF-1Î± in a FOXO3-dependent mechanism Priority Research Paper

Heptamethine carbocyanine dye-mediated near-infrared imaging of canine and human cancers through the HIF-1Î±/OATPs signaling axis Research Paper

Phospholipase D1 protein coordinates dynamic assembly of HIF-1Î±-PHD-VHL to regulate HIF-1Î± stability Research Paper

Chemopreventive apigenin controls UVB-induced cutaneous proliferation and angiogenesis through HuR and thrombospondin-1 Research Paper

Hypoxia-inducible factors enhance glutamate signaling in cancer cells Priority Research Paper

HS-133, a novel fluorescent phosphatidylinositol 3-kinase inhibitor as a potential imaging and anticancer agent for targeted therapy Research Paper

MiR-578 and miR-573 as potential players in BRCA-related breast cancer angiogenesis Research Paper

P2Y₂R activation by nucleotides released from the highly metastatic breast cancer cell contributes to pre-metastatic niche formation by mediating lysyl oxidase secretion, collagen crosslinking, and monocyte recruitment Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Hepatitis B virus X protein induces expression of alpha-fetoprotein and activates PI3K/mTOR signaling pathway in liver cells Research Paper

Induction of cellular prion protein (PrPc) under hypoxia inhibits apoptosis caused by TRAIL treatment Research Paper

Zoledronic acid overcomes chemoresistance and immunosuppression of malignant mesothelioma Research Paper

Ferroxitosis: A cell death from modulation of oxidative phosphorylation and PKM2-dependent glycolysis in melanoma Research Paper

Hypoxia-inducible factor 1 mediates TAZ expression and nuclear localization to induce the breast cancer stem cell phenotype Priority Research Paper

Hypoxia induces a lipogenic cancer cell phenotype via HIF1Î±-dependent and -independent pathways Priority Research Paper

Hypoxia up-regulates SERPINB3 through HIF-2Î± in human liver cancer cells Research Paper

Inhibition of HIF-1Î± by PX-478 enhances the anti-tumor effect of gemcitabine by inducing immunogenic cell death in pancreatic ductal adenocarcinoma Research Paper

Î³-H2AX promotes hepatocellular carcinoma angiogenesis via EGFR/HIF-1Î±/VEGF pathways under hypoxic condition Research Paper

Hypoxia-inducible factor 1 alpha is regulated by RBM38, a RNA-binding protein and a p53 family target, via mRNA translation Research Paper

Inhibition of succinate dehydrogenase by the mitochondrial chaperone TRAP1 has anti-oxidant and anti-apoptotic effects on tumor cells Research Paper

Targeting hypoxia-inducible factor-1Î± (HIF-1Î±) in combination with antiangiogenic therapy: A phase I trial of bortezomib plus bevacizumab Clinical Research Papers

Syringaresinol protects against hypoxia/reoxygenation-induced cardiomyocytes injury and death by destabilization of HIF-1Î± in a FOXO3-dependent mechanism Priority Research Paper

Heptamethine carbocyanine dye-mediated near-infrared imaging of canine and human cancers through the HIF-1Î±/OATPs signaling axis Research Paper

Phospholipase D1 protein coordinates dynamic assembly of HIF-1Î±-PHD-VHL to regulate HIF-1Î± stability Research Paper

Chemopreventive apigenin controls UVB-induced cutaneous proliferation and angiogenesis through HuR and thrombospondin-1 Research Paper

Hypoxia-inducible factors enhance glutamate signaling in cancer cells Priority Research Paper

HS-133, a novel fluorescent phosphatidylinositol 3-kinase inhibitor as a potential imaging and anticancer agent for targeted therapy Research Paper

MiR-578 and miR-573 as potential players in BRCA-related breast cancer angiogenesis Research Paper

P2Y2R activation by nucleotides released from the highly metastatic breast cancer cell contributes to pre-metastatic niche formation by mediating lysyl oxidase secretion, collagen crosslinking, and monocyte recruitment Research Paper

P2Y₂R activation by nucleotides released from the highly metastatic breast cancer cell contributes to pre-metastatic niche formation by mediating lysyl oxidase secretion, collagen crosslinking, and monocyte recruitment Research Paper