The Oncosearch | Oncotarget

Basal and therapy-driven hypoxia-inducible factor-1α confers resistance to endocrine therapy in estrogen receptor-positive breast cancer Research Paper

Xiaoqing Jia, Qi Hong, Li Lei, Daqiang Li, Jianwei Li, Miao Mo, Yujie Wang, Zhimin Shao, Zhenzhou Shen, Jingyi Cheng, Guangyu Liu

Published Apr 13, 2015 · Vol. 6, No. 11 · pp. 8648-8662

Molecular signatures of sanguinarine in human pancreatic cancer cells: A large scale label-free comparative proteomics approach Research Paper

Chandra K. Singh, Satwinderjeet Kaur, Jasmine George, Minakshi Nihal, Molly C. Pellitteri Hahn, Cameron O. Scarlett, Nihal Ahmad

Published Apr 13, 2015 · Vol. 6, No. 12 · pp. 10335-10349

Tanshinone I inhibits tumor angiogenesis by reducing STAT3 phosphorylation at TYR705 and hypoxia-induced HIF-1Î± accumulation in both endothelial and tumor cells Research Paper

Yan Wang, Jia-Xin Li, Ying-Qing Wang, Ze-Hong Miao

Published Apr 10, 2015 · Vol. 6, No. 18 · pp. 16031-16042

Distinct von Hippel-Lindau gene and hypoxia-regulated alterations in gene and protein expression patterns of renal cell carcinoma and their effects on metabolism Research Paper

Sandra Leisz, Kristin Schulz, Susanne Erb, Peter Oefner, Katja Dettmer, Dimitrios Mougiakakos, Ena Wang, Francesco M. Marincola, Franziska Stehle, Barbara Seliger

Published Mar 27, 2015 · Vol. 6, No. 13 · pp. 11395-11406

Recurrence of glioblastoma after radio-chemotherapy is associated with an angiogenic switch to the CXCL12-CXCR4 pathway Research Paper

Emeline Tabouret, Aurelie Tchoghandjian, Emilie Denicolai, Christine Delfino, Philippe Metellus, Thomas Graillon, Celine Boucard, Isabelle Nanni, Laetitia Padovani, Lâ€™Houcine Ouafik, Dominique Figarella-Branger, Olivier Chinot

Published Mar 25, 2015 · Vol. 6, No. 13 · pp. 11664-11675

Aquaporin 1 and 5 expression decreases during human intervertebral disc degeneration: novel HIF-1-mediated regulation of aquaporins in NP cells Research Paper

Zariel I. Johnson, Shilpa S. Gogate, Rebecca Day, Abbie Binch, Dessislava Z. Markova, Neil Chiverton, Ashley Cole, Matt Conner, Irving M. Shapiro, Christine L. Le Maitre, Makarand V. Risbud

Published Mar 20, 2015 · Vol. 6, No. 14 · pp. 11945-11958

AMPK-mediated energy homeostasis and associated metabolic effects on cancer cell response and resistance to cetuximab Research Paper

Xinqun Li, Yang Lu, Haiquan Lu, Jingtao Luo, Yun Hong, Zhen Fan

Published Mar 20, 2015 · Vol. 6, No. 13 · pp. 11507-11518

Temporal regulation of HIF-1 and NF-ÎºB in hypoxic hepatocarcinoma cells Research Paper

Yuan Jiang, Ying Zhu, Xinxin Wang, Juan Gong, Chunyan Hu, Bo Guo, Bo Zhu, Yongsheng Li

Published Mar 19, 2015 · Vol. 6, No. 11 · pp. 9409-9419

A novel HIF-1Î±-integrin-linked kinase regulatory loop that facilitates hypoxia-induced HIF-1Î± expression and epithelial-mesenchymal transition in cancer cells Research Paper

Chih-Chien Chou, Hsaio-Ching Chuang, Santosh B. Salunke, Samuel K. Kulp, Ching-Shih Chen

Published Mar 16, 2015 · Vol. 6, No. 10 · pp. 8271-8285

Activation of hypoxia signaling induces phenotypic transformation of glioma cells: implications for bevacizumab antiangiogenic therapy Priority Research Paper

Hui Xu, Shervin Rahimpour, Cody L. Nesvick, Xu Zhang, Jingyun Ma, Min Zhang, Ge Zhang, Li Wang, Chunzhang Yang, Christopher S. Hong, Anand V. Germanwala, J. Bradley Elder, Abhik Ray-Chaudhury, Yu Yao, Mark R. Gilbert, Russell R. Lonser, John D. Heiss, Roscoe O. Brady, Ying Mao, Jianhua Qin, Zhengping Zhuang

Published Mar 14, 2015 · Vol. 6, No. 14 · pp. 11882-11893

Hypoxia-inducible factor 1Î± (HIF-1Î±) and reactive oxygen species (ROS) mediates radiation-induced invasiveness through the SDF-1Î±/CXCR4 pathway in non-small cell lung carcinoma cells Research Paper

Qing Gu, Yan He, Jianfeng Ji, Yifan Yao, Wenhao Shen, Jialin Luo, Wei Zhu, Han Cao, Yangyang Geng, Jing Xu, Shuyu Zhang, Jianping Cao, Wei-Qun Ding

Published Mar 12, 2015 · Vol. 6, No. 13 · pp. 10893-10907

Sunitinib but not VEGF blockade inhibits cancer stem cell endothelial differentiation Research Paper

Alessia Brossa, Cristina Grange, Letizia Mancuso, Laura Annaratone, Maria Antonietta Satolli, Massimiliano Mazzone, Giovanni Camussi, Benedetta Bussolati

Published Feb 28, 2015 · Vol. 6, No. 13 · pp. 11295-11309

Osteopontin promotes a cancer stem cell-like phenotype in hepatocellular carcinoma cells via an integrinâ€“NF-ÎºBâ€“HIF-1Î± pathway Research Paper

Lei Cao, Xiaoyu Fan, Wei Jing, Yingchao Liang, Rui Chen, Yingying Liu, Minhui Zhu, Rongjie Jia, Hao Wang, Xueguang Zhang, Yanyun Zhang, Xuyu Zhou, Jian Zhao, Yajun Guo

Published Feb 25, 2015 · Vol. 6, No. 9 · pp. 6627-6640

Increase of miR-199a-5p by protoporphyrin IX, a photocatalyzer, directly inhibits E2F3, sensitizing mesenchymal tumor cells to anti-cancer agents Research Paper

Jung Min Lee, Mi Jeong Heo, Chan Gyu Lee, Yoon Mee Yang, Sang Geon Kim

Published Feb 24, 2015 · Vol. 6, No. 6 · pp. 3918-3931

ZBRK1, a novel tumor suppressor, activates VHL gene transcription through formation of a complex with VHL and p300 in renal cancer Research Paper

Ke Chen, Gan Yu, Kiranmai Gumireddy, Anping Li, Weimin Yao, Lu Gao, Shuliang Chen, Jun Hao, Ji Wang, Qihong Huang, Hua Xu, Zhangqun Ye

Published Feb 10, 2015 · Vol. 6, No. 9 · pp. 6959-6976

WISP-1, a novel angiogenic regulator of the CCN family, promotes oral squamous cell carcinoma angiogenesis through VEGF-A expression Research Paper

Jing-Yuan Chuang, Po-Chun Chen, Ching-Wen Tsao, An-Chen Chang, Ming-Yu Lein, Ching-Chia Lin, Shih-Wei Wang, Chiao-Wen Lin, Chih-Hsin Tang

Published Jan 30, 2015 · Vol. 6, No. 6 · pp. 4239-4252

Neutralizing S1P inhibits intratumoral hypoxia, induces vascular remodelling and sensitizes to chemotherapy in prostate cancer Research Paper

Isabelle Ader, CÃ©cile Gstalder, Pierre Bouquerel, Muriel Golzio, Guillaume Andrieu, Santiago Zalvidea, Sylvain Richard, Roger A. Sabbadini, Bernard Malavaud, Olivier Cuvillier

Published Jan 29, 2015 · Vol. 6, No. 15 · pp. 13803-13821

Hypoxia/HIF1α induces lapatinib resistance in ERBB2-positive breast cancer cells via regulation of DUSP2 Research Paper

Sergey V. Karakashev, Mauricio J. Reginato

Published Jan 24, 2015 · Vol. 6, No. 4 · pp. 1967-1980

HIF-2Î± mediates hypoxia-induced LIF expression in human colorectal cancer cells Research Paper

Lihua Wu, Haiyang Yu, Yuhan Zhao, Cen Zhang, Jiabei Wang, Xuetian Yue, Qifeng Yang, Wenwei Hu

Published Jan 22, 2015 · Vol. 6, No. 6 · pp. 4406-4417

EBV-LMP1 targeted DNAzyme enhances radiosensitivity by inhibiting tumor angiogenesis via the JNKs/HIF-1 pathway in nasopharyngeal carcinoma Research Paper

Lifang Yang, Liyu Liu, Zhijie Xu, Weihua Liao, Deyun Feng, Xin Dong, San Xu, Lanbo Xiao, Jingchen Lu, Xiangjian Luo, Min Tang, Ann M. Bode, Zigang Dong, Lunquan Sun, Ya Cao

Published Jan 21, 2015 · Vol. 6, No. 8 · pp. 5804-5817

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European Cancer and Oncology Congress

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Search Oncotarget

Basal and therapy-driven hypoxia-inducible factor-1α confers resistance to endocrine therapy in estrogen receptor-positive breast cancer Research Paper

Molecular signatures of sanguinarine in human pancreatic cancer cells: A large scale label-free comparative proteomics approach Research Paper

Tanshinone I inhibits tumor angiogenesis by reducing STAT3 phosphorylation at TYR705 and hypoxia-induced HIF-1Î± accumulation in both endothelial and tumor cells Research Paper

Distinct von Hippel-Lindau gene and hypoxia-regulated alterations in gene and protein expression patterns of renal cell carcinoma and their effects on metabolism Research Paper

Recurrence of glioblastoma after radio-chemotherapy is associated with an angiogenic switch to the CXCL12-CXCR4 pathway Research Paper

Aquaporin 1 and 5 expression decreases during human intervertebral disc degeneration: novel HIF-1-mediated regulation of aquaporins in NP cells Research Paper

AMPK-mediated energy homeostasis and associated metabolic effects on cancer cell response and resistance to cetuximab Research Paper

Temporal regulation of HIF-1 and NF-ÎºB in hypoxic hepatocarcinoma cells Research Paper

A novel HIF-1Î±-integrin-linked kinase regulatory loop that facilitates hypoxia-induced HIF-1Î± expression and epithelial-mesenchymal transition in cancer cells Research Paper

Activation of hypoxia signaling induces phenotypic transformation of glioma cells: implications for bevacizumab antiangiogenic therapy Priority Research Paper

Hypoxia-inducible factor 1Î± (HIF-1Î±) and reactive oxygen species (ROS) mediates radiation-induced invasiveness through the SDF-1Î±/CXCR4 pathway in non-small cell lung carcinoma cells Research Paper

Sunitinib but not VEGF blockade inhibits cancer stem cell endothelial differentiation Research Paper

Osteopontin promotes a cancer stem cell-like phenotype in hepatocellular carcinoma cells via an integrinâ€“NF-ÎºBâ€“HIF-1Î± pathway Research Paper

Increase of miR-199a-5p by protoporphyrin IX, a photocatalyzer, directly inhibits E2F3, sensitizing mesenchymal tumor cells to anti-cancer agents Research Paper

ZBRK1, a novel tumor suppressor, activates VHL gene transcription through formation of a complex with VHL and p300 in renal cancer Research Paper

WISP-1, a novel angiogenic regulator of the CCN family, promotes oral squamous cell carcinoma angiogenesis through VEGF-A expression Research Paper

Neutralizing S1P inhibits intratumoral hypoxia, induces vascular remodelling and sensitizes to chemotherapy in prostate cancer Research Paper

Hypoxia/HIF1α induces lapatinib resistance in ERBB2-positive breast cancer cells via regulation of DUSP2 Research Paper

HIF-2Î± mediates hypoxia-induced LIF expression in human colorectal cancer cells Research Paper

EBV-LMP1 targeted DNAzyme enhances radiosensitivity by inhibiting tumor angiogenesis via the JNKs/HIF-1 pathway in nasopharyngeal carcinoma Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Basal and therapy-driven hypoxia-inducible factor-1α confers resistance to endocrine therapy in estrogen receptor-positive breast cancer Research Paper

Molecular signatures of sanguinarine in human pancreatic cancer cells: A large scale label-free comparative proteomics approach Research Paper

Tanshinone I inhibits tumor angiogenesis by reducing STAT3 phosphorylation at TYR705 and hypoxia-induced HIF-1Î± accumulation in both endothelial and tumor cells Research Paper

Distinct von Hippel-Lindau gene and hypoxia-regulated alterations in gene and protein expression patterns of renal cell carcinoma and their effects on metabolism Research Paper

Recurrence of glioblastoma after radio-chemotherapy is associated with an angiogenic switch to the CXCL12-CXCR4 pathway Research Paper

Aquaporin 1 and 5 expression decreases during human intervertebral disc degeneration: novel HIF-1-mediated regulation of aquaporins in NP cells Research Paper

AMPK-mediated energy homeostasis and associated metabolic effects on cancer cell response and resistance to cetuximab Research Paper

Temporal regulation of HIF-1 and NF-ÎºB in hypoxic hepatocarcinoma cells Research Paper

A novel HIF-1Î±-integrin-linked kinase regulatory loop that facilitates hypoxia-induced HIF-1Î± expression and epithelial-mesenchymal transition in cancer cells Research Paper

Activation of hypoxia signaling induces phenotypic transformation of glioma cells: implications for bevacizumab antiangiogenic therapy Priority Research Paper

Hypoxia-inducible factor 1Î± (HIF-1Î±) and reactive oxygen species (ROS) mediates radiation-induced invasiveness through the SDF-1Î±/CXCR4 pathway in non-small cell lung carcinoma cells Research Paper

Sunitinib but not VEGF blockade inhibits cancer stem cell endothelial differentiation Research Paper

Osteopontin promotes a cancer stem cell-like phenotype in hepatocellular carcinoma cells via an integrinâ€“NF-ÎºBâ€“HIF-1Î± pathway Research Paper

Increase of miR-199a-5p by protoporphyrin IX, a photocatalyzer, directly inhibits E2F3, sensitizing mesenchymal tumor cells to anti-cancer agents Research Paper

ZBRK1, a novel tumor suppressor, activates VHL gene transcription through formation of a complex with VHL and p300 in renal cancer Research Paper

WISP-1, a novel angiogenic regulator of the CCN family, promotes oral squamous cell carcinoma angiogenesis through VEGF-A expression Research Paper

Neutralizing S1P inhibits intratumoral hypoxia, induces vascular remodelling and sensitizes to chemotherapy in prostate cancer Research Paper

Hypoxia/HIF1α induces lapatinib resistance in ERBB2-positive breast cancer cells via regulation of DUSP2 Research Paper

HIF-2Î± mediates hypoxia-induced LIF expression in human colorectal cancer cells Research Paper

EBV-LMP1 targeted DNAzyme enhances radiosensitivity by inhibiting tumor angiogenesis via the JNKs/HIF-1 pathway in nasopharyngeal carcinoma Research Paper