The Oncosearch | Oncotarget

The Jumonji-domain histone demethylase inhibitor JIB-04 deregulates oncogenic programs and increases DNA damage in Ewing Sarcoma, resulting in impaired cell proliferation and survival, and reduced tumor growth Research Paper

Janet K. Parrish, Tyler S. McCann, Marybeth Sechler, Lays M. Sobral, Wen Hua Ren, Kenneth L. Jones, Aik Choon Tan, Paul Jedlicka

Published Sep 4, 2018 · Vol. 9, No. 69 · pp. 33110-33123

Investigation of novel chemotherapeutics for feline oral squamous cell carcinoma Research Paper

Hunter John Piegols, Marilia Takada, Maciej Parys, Thomas Dexheimer, Vilma Yuzbasiyan-Gurkan

Published Sep 4, 2018 · Vol. 9, No. 69 · pp. 33098-33109

MAP17 (PDZK1IP1) and pH2AX are potential predictive biomarkers for rectal cancer treatment efficacy Research Paper

Maria Rivero, Javier Peinado-Serrano, Sandra MuÃ±oz-Galvan, Asuncion Espinosa-SÃ¡nchez, Elisa Suarez-Martinez, Blanca Felipe-Abrio, Maria Carmen FernÃ¡ndez-FernÃ¡ndez, Maria Jose Ortiz, Amancio Carnero

Published Aug 31, 2018 · Vol. 9, No. 68 · pp. 32958-32971

Constitutive activation and overexpression of NF-ÎºB/c-Rel in conjunction with p50 contribute to aggressive tongue tumorigenesis Research Paper

Shilpi Gupta, Prabhat Kumar, Harsimrut Kaur, Nishi Sharma, Sunita Gupta, Daman Saluja, Alok C. Bharti, Bhudev Das

Published Aug 31, 2018 · Vol. 9, No. 68 · pp. 33011-33029

Differential signaling pathway activation in 7,12-dimethylbenz[a] anthracene (DMBA)-treated mammary stem/progenitor cells from species with varying mammary cancer incidence Research Paper

Melissa M. Ledet, Meghan Oswald, Robyn Anderson, Gerlinde R. Van de Walle

Published Aug 28, 2018 · Vol. 9, No. 67 · pp. 32761-32774

Vitamin C promotes decitabine or azacytidine induced DNA hydroxymethylation and subsequent reactivation of the epigenetically silenced tumour suppressor CDKN1A in colon cancer cells Research Paper

Christian Gerecke, Fabian Schumacher, Alexander Edlich, Alexandra Wetzel, Guy Yealland, Lena Katharina Neubert, Bettina Scholtka, Thomas Homann, Burkhard Kleuser

Published Aug 28, 2018 · Vol. 9, No. 67 · pp. 32822-32840

Beyond the 3â€²UTR bindingâ€“microRNA-induced protein truncation via DNA binding Research Paper

Melanie von Brandenstein, Stephan H. Bernhart, Andreas Pansky, Claudia Richter, Tobias Kohl, Martina Deckert, Axel Heidenreich, Peter F. Stadler, Manuel Montesinos-Rongen, Jochen W.U. Fries

Published Aug 28, 2018 · Vol. 9, No. 67 · pp. 32855-32867

Circulating tumor DNA as a marker of treatment response in BRAF V600E mutated non-melanoma solid tumors Research Paper

Lise Barlebo Ahlborn, Ida Viller Tuxen, Florent Mouliere, Savvas Kinalis, Ane Y. Schmidt, Kristoffer Staal Rohrberg, Eric Santoni-Rugiu, Finn Cilius Nielsen, Ulrik Lassen, Christina Westmose Yde, Olga Oestrup, Morten Mau-Sorensen

Published Aug 24, 2018 · Vol. 9, No. 66 · pp. 32570-32579

The frequency of promoter DNA hypermethylation is decreased in colorectal neoplasms of familial adenomatous polyposis Research Paper

Kiyoko Takane, Masaki Fukuyo, Keisuke Matsusaka, Satoshi Ota, Bahityar Rahmutulla, Kazuyuki Matsushita, Hideaki Miyauchi, Yukio Nakatani, Hisahiro Matsubara, Atsushi Kaneda

Published Aug 24, 2018 · Vol. 9, No. 66 · pp. 32653-32666

A high-throughput fluorescence polarization assay for discovering inhibitors targeting the DNA-binding domain of signal transducer and activator of transcription 3 (STAT3) Research Paper

Po-Chang Shih, Yiwen Yang, Gary N. Parkinson, Andrew Wilderspin, Geoffrey Wells

Published Aug 24, 2018 · Vol. 9, No. 66 · pp. 32690-32701

Illuminating the route of precision medicine and inhibitor discovery: real-time measurement of DNA repair capacity with molecular beacons News

Alfonso Bellacosa, Timothy Yen

Published Aug 22, 2018 · Vol. 9, No. 96 · pp. 36818-36819

â€œTwo hits - one stoneâ€; increased efficacy of cisplatin-based therapies by targeting PCNAâ€™s role in both DNA repair and cellular signaling Research Paper

Caroline Krogh SÃ¸gaard, Augun Blindheim, Lisa M. RÃ¸st, Voin PetroviÄ‡, Anala Nepal, Siri Bachke, Nina-Beate Liabakk, Odrun A. Gederaas, Trond Viset, Carl-JÃ¸rgen Arum, Per Bruheim, Marit Otterlei

Published Aug 21, 2018 · Vol. 9, No. 65 · pp. 32448-32465

A novel molecular mechanism for a long non-coding RNA PCAT92 implicated in prostate cancer Research Paper

Pushpinder Singh Bawa, Samathmika Ravi, Swagatika Paul, Bibha Chaudhary, Subhashini Srinivasan

Published Aug 21, 2018 · Vol. 9, No. 65 · pp. 32419-32434

xCT inhibition sensitizes tumors to Î³-radiation via glutathione reduction Research Paper

Lara Cobler, Hui Zhang, Poojan Suri, Catherine Park, Luika A. Timmerman

Published Aug 17, 2018 · Vol. 9, No. 64 · pp. 32280-32297

Somatic genome alterations in relation to age in lung squamous cell carcinoma Research Paper

Stefano Meucci, Ulrich Keilholz, Daniel Heim, Frederick Klauschen, Stefano Cacciatore

Published Aug 14, 2018 · Vol. 9, No. 63 · pp. 32161-32172

Discovery of DEBIC to correlate P-selectin inhibition and DNA intercalation in cancer therapy and complicated thrombosis Research Paper

Haiyan Chen, Wenjing Wang, Xiaoyi Zhang, Shan Liu, Yaonan Wang, Haimei Zhu, Jianhui Wu, Yuji Wang, Ming Zhao, Shiqi Peng

Published Aug 14, 2018 · Vol. 9, No. 63 · pp. 32119-32133

Identification of key pathways and genes in response to trastuzumab treatment in breast cancer using bioinformatics analysis Research Paper

Fanxin Zeng, Jiangping Fu, Fang Hu, Yani Tang, Xiangdong Fang, Fanwei Zeng, Yanpeng Chu

Published Aug 14, 2018 · Vol. 9, No. 63 · pp. 32149-32160

Investigation of appropriate pre-analytical procedure for circulating free DNA from liquid biopsy Research Paper

Akemi Sato, Chiho Nakashima, Tomonori Abe, Junichi Kato, Mitsuharu Hirai, Tomomi Nakamura, Kazutoshi Komiya, Shinya Kimura, Eisaburo Sueoka, Naoko Sueoka-Aragane

Published Aug 7, 2018 · Vol. 9, No. 61 · pp. 31904-31914

DNA Repair Molecular Beacon assay: a platform for real-time functional analysis of cellular DNA repair capacity Research Paper

Jianfeng Li, David Svilar, Steven McClellan, Jung-Hyun Kim, Eun-Young Erin Ahn, Conchita Vens, David M. Wilson III, Robert W. Sobol

Published Aug 3, 2018 · Vol. 9, No. 60 · pp. 31719-31743

Deep analysis of acquired resistance to FGFR1 inhibitor identifies MET and AKT activation and an expansion of AKT1 mutant cells Research Paper

Pol Gimenez-Xavier, Eva Pros, Ana Aza, Sebastian Moran, Raul Tonda, Anna Esteve-Codina, Marc Dabad, Montse Sanchez-Cespedes

Published Jul 31, 2018 · Vol. 9, No. 59 · pp. 31549-31558

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The Jumonji-domain histone demethylase inhibitor JIB-04 deregulates oncogenic programs and increases DNA damage in Ewing Sarcoma, resulting in impaired cell proliferation and survival, and reduced tumor growth Research Paper

Investigation of novel chemotherapeutics for feline oral squamous cell carcinoma Research Paper

MAP17 (PDZK1IP1) and pH2AX are potential predictive biomarkers for rectal cancer treatment efficacy Research Paper

Constitutive activation and overexpression of NF-ÎºB/c-Rel in conjunction with p50 contribute to aggressive tongue tumorigenesis Research Paper

Differential signaling pathway activation in 7,12-dimethylbenz[a] anthracene (DMBA)-treated mammary stem/progenitor cells from species with varying mammary cancer incidence Research Paper

Vitamin C promotes decitabine or azacytidine induced DNA hydroxymethylation and subsequent reactivation of the epigenetically silenced tumour suppressor CDKN1A in colon cancer cells Research Paper

Beyond the 3â€²UTR bindingâ€“microRNA-induced protein truncation via DNA binding Research Paper

Circulating tumor DNA as a marker of treatment response in BRAF V600E mutated non-melanoma solid tumors Research Paper

The frequency of promoter DNA hypermethylation is decreased in colorectal neoplasms of familial adenomatous polyposis Research Paper

A high-throughput fluorescence polarization assay for discovering inhibitors targeting the DNA-binding domain of signal transducer and activator of transcription 3 (STAT3) Research Paper

Illuminating the route of precision medicine and inhibitor discovery: real-time measurement of DNA repair capacity with molecular beacons News

â€œTwo hits - one stoneâ€; increased efficacy of cisplatin-based therapies by targeting PCNAâ€™s role in both DNA repair and cellular signaling Research Paper

A novel molecular mechanism for a long non-coding RNA PCAT92 implicated in prostate cancer Research Paper

xCT inhibition sensitizes tumors to Î³-radiation via glutathione reduction Research Paper

Somatic genome alterations in relation to age in lung squamous cell carcinoma Research Paper

Discovery of DEBIC to correlate P-selectin inhibition and DNA intercalation in cancer therapy and complicated thrombosis Research Paper

Identification of key pathways and genes in response to trastuzumab treatment in breast cancer using bioinformatics analysis Research Paper

Investigation of appropriate pre-analytical procedure for circulating free DNA from liquid biopsy Research Paper

DNA Repair Molecular Beacon assay: a platform for real-time functional analysis of cellular DNA repair capacity Research Paper

Deep analysis of acquired resistance to FGFR1 inhibitor identifies MET and AKT activation and an expansion of AKT1 mutant cells Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

The Jumonji-domain histone demethylase inhibitor JIB-04 deregulates oncogenic programs and increases DNA damage in Ewing Sarcoma, resulting in impaired cell proliferation and survival, and reduced tumor growth Research Paper

Investigation of novel chemotherapeutics for feline oral squamous cell carcinoma Research Paper

MAP17 (PDZK1IP1) and pH2AX are potential predictive biomarkers for rectal cancer treatment efficacy Research Paper

Constitutive activation and overexpression of NF-ÎºB/c-Rel in conjunction with p50 contribute to aggressive tongue tumorigenesis Research Paper

Differential signaling pathway activation in 7,12-dimethylbenz[a] anthracene (DMBA)-treated mammary stem/progenitor cells from species with varying mammary cancer incidence Research Paper

Vitamin C promotes decitabine or azacytidine induced DNA hydroxymethylation and subsequent reactivation of the epigenetically silenced tumour suppressor CDKN1A in colon cancer cells Research Paper

Beyond the 3â€²UTR bindingâ€“microRNA-induced protein truncation via DNA binding Research Paper

Circulating tumor DNA as a marker of treatment response in BRAF V600E mutated non-melanoma solid tumors Research Paper

The frequency of promoter DNA hypermethylation is decreased in colorectal neoplasms of familial adenomatous polyposis Research Paper

A high-throughput fluorescence polarization assay for discovering inhibitors targeting the DNA-binding domain of signal transducer and activator of transcription 3 (STAT3) Research Paper

Illuminating the route of precision medicine and inhibitor discovery: real-time measurement of DNA repair capacity with molecular beacons News

â€œTwo hits - one stoneâ€; increased efficacy of cisplatin-based therapies by targeting PCNAâ€™s role in both DNA repair and cellular signaling Research Paper

A novel molecular mechanism for a long non-coding RNA PCAT92 implicated in prostate cancer Research Paper

xCT inhibition sensitizes tumors to Î³-radiation via glutathione reduction Research Paper

Somatic genome alterations in relation to age in lung squamous cell carcinoma Research Paper

Discovery of DEBIC to correlate P-selectin inhibition and DNA intercalation in cancer therapy and complicated thrombosis Research Paper

Identification of key pathways and genes in response to trastuzumab treatment in breast cancer using bioinformatics analysis Research Paper

Investigation of appropriate pre-analytical procedure for circulating free DNA from liquid biopsy Research Paper

DNA Repair Molecular Beacon assay: a platform for real-time functional analysis of cellular DNA repair capacity Research Paper

Deep analysis of acquired resistance to FGFR1 inhibitor identifies MET and AKT activation and an expansion of AKT1 mutant cells Research Paper

â€œTwo hits - one stoneâ€; increased efficacy of cisplatin-based therapies by targeting PCNAâ€™s role in both DNA repair and cellular signaling Research Paper