The Oncosearch | Oncotarget

Reciprocal positive selection for weakness - preventing olaparib resistance by inhibiting BRCA2 Research Paper

Mateusz Rytelewski, Saman Maleki Vareki, Lingegowda S. Mangala, Larissa Romanow, Dahai Jiang, Sunila Pradeep, Christian Rodriguez-Aguayo, Gabriel Lopez-Berestein, Rene Figueredo, Peter J. Ferguson, Mark Vincent, Anil K. Sood, James D. Koropatnick

Published Mar 3, 2016 · Vol. 7, No. 15 · pp. 20825-20839

Camptothecin targets WRN protein: mechanism and relevance in clinical breast cancer Priority Research Paper

Raghavendra A. Shamanna, Huiming Lu, Deborah L. Croteau, Arvind Arora, Devika Agarwal, Graham Ball, Mohammed A. Aleskandarany, Ian O. Ellis, Yves Pommier, Srinivasan Madhusudan, Vilhelm A. Bohr

Published Mar 3, 2016 · Vol. 7, No. 12 · pp. 13269-13284

The antihypertensive drug hydralazine activates the intrinsic pathway of apoptosis and causes DNA damage in leukemic T cells Research Paper

MarÃa J. Ruiz-MagaÃ±a, RocÃo MartÃnez-Aguilar, EstefanÃa Lucendo, Diana Campillo-Davo, Klaus Schulze-Osthoff, Carmen Ruiz-Ruiz

Published Mar 3, 2016 · Vol. 7, No. 16 · pp. 21875-21886

Prp19 facilitates invasion of hepatocellular carcinoma via p38 mitogen-activated protein kinase/Twist1 pathway Research Paper

Jie Yin, Lan Wang, Ji-Min Zhu, Qian Yu, Ru-Yi Xue, Ying Fang, Yi-An Zhang, Yan-Jie Chen, Tao-Tao Liu, Ling Dong, Xi-Zhong Shen

Published Mar 3, 2016 · Vol. 7, No. 16 · pp. 21939-21951

Cinobufagin inhibits tumor growth by inducing intrinsic apoptosis through AKT signaling pathway in human nonsmall cell lung cancer cells Research Paper

Guangxin Zhang, Chao Wang, Mei Sun, Jindong Li, Bin Wang, Chengyan Jin, Peiyan Hua, Ge Song, Yifan Zhang, Lisa L.H. Nguyen, Ranji Cui, Runhua Liu, Lizhong Wang, Xingyi Zhang

Published Mar 3, 2016 · Vol. 7, No. 20 · pp. 28935-28946

Loss of p53-mediated cell-cycle arrest, senescence and apoptosis promotes genomic instability and premature aging Priority Research Paper

Tongyuan Li, Xiangyu Liu, Le Jiang, James Manfredi, Shan Zha, Wei Gu

Published Mar 2, 2016 · Vol. 7, No. 11 · pp. 11838-11849

Common DNA methylation alterations of Alzheimerâ€™s disease and aging in peripheral whole blood Research Paper

Hongdong Li, Zheng Guo, You Guo, Mengyao Li, Haidan Yan, Jun Cheng, Chenguang Wang, Guini Hong

Published Mar 2, 2016 · Vol. 7, No. 15 · pp. 19089-19098

Development of a novel HAC-based â€œgain of signalâ€ quantitative assay for measuring chromosome instability (CIN) in cancer cells Research Paper

Jung-Hyun Kim, Hee-Sheung Lee, Nicholas C. O. Lee, Nikolay V. Goncharov, Vadim Kumeiko, Hiroshi Masumoto, William C. Earnshaw, Natalay Kouprina, Vladimir Larionov

Published Mar 2, 2016 · Vol. 7, No. 12 · pp. 14841-14856

Cancer therapeutic approach based on conformational stabilization of mutant p53 protein by small peptides Priority Research Paper

Perry Tal, Shay Eizenberger, Elad Cohen, Naomi Goldfinger, Shmuel Pietrokovski, Moshe Oren, Varda Rotter

Published Mar 2, 2016 · Vol. 7, No. 11 · pp. 11817-11837

Repeated PM2.5 exposure inhibits BEAS-2B cell P53 expression through ROS-Akt-DNMT3B pathway-mediated promoter hypermethylation Research Paper

Wei Zhou, Dongdong Tian, Jun He, Yimei Wang, Lijun Zhang, Lan Cui, Li Jia, Li Zhang, Lizhong Li, Yulei Shu, Shouzhong Yu, Jun Zhao, Xiaoyan Yuan, Shuangqing Peng

Published Mar 2, 2016 · Vol. 7, No. 15 · pp. 20691-20703

Tau accumulation impairs mitophagy via increasing mitochondrial membrane potential and reducing mitochondrial Parkin Research Paper

Yu Hu, Xia-Chun Li, Zhi-hao Wang, Yu Luo, Xiangnan Zhang, Xiu-Ping Liu, Qiong Feng, Qun Wang, Zhenyu Yue, Zhong Chen, Keqiang Ye, Jian-Zhi Wang, Gong-Ping Liu

Published Mar 2, 2016 · Vol. 7, No. 14 · pp. 17356-17368

Ran Binding Protein 9 (RanBP9) is a novel mediator of cellular DNA damage response in lung cancer cells Research Paper

Dario Palmieri, Mario Scarpa, Anna Tessari, Rexhep Uka, Foued Amari, Cindy Lee, Timothy Richmond, Claudia Foray, Tyler Sheetz, Ashley Braddom, Christin E. Burd, Jeffrey D. Parvin, Thomas Ludwig, Carlo M. Croce, Vincenzo Coppola

Published Mar 1, 2016 · Vol. 7, No. 14 · pp. 18371-18383

Smoking-promoted oxidative DNA damage response is highly correlated to lung carcinogenesis Research Paper

Chao Cao, Tianwen Lai, Miao Li, Hongbin Zhou, Dan Lv, Zaichun Deng, Songmin Ying, Zhihua Chen, Wen Li, Huahao Shen

Published Mar 1, 2016 · Vol. 7, No. 14 · pp. 18919-18926

Alkaline ceramidase 2 and its bioactive product sphingosine are novel regulators of the DNA damage response Research Paper

Ruijuan Xu, Kai Wang, Izolda Mileva, Yusuf A. Hannun, Lina M. Obeid, Cungui Mao

Published Mar 1, 2016 · Vol. 7, No. 14 · pp. 18440-18457

BRAF and TERT promoter mutations in the aggressiveness of papillary thyroid carcinoma: a study of 653 patients Research Paper

Langping Jin, Endong Chen, Siyang Dong, Yefeng Cai, Xiangjian Zhang, Yili Zhou, Ruichao Zeng, Fan Yang, Chuanmeng Pan, Yehuan Liu, Weili Wu, Mingzhao Xing, Xiaohua Zhang, Ouchen Wang

Published Mar 1, 2016 · Vol. 7, No. 14 · pp. 18346-18355

Overexpression of pig selenoprotein S blocks OTA-induced promotion of PCV2 replication by inhibiting oxidative stress and p38 phosphorylation in PK15 cells Research Paper

Fang Gan, Zhihua Hu, Yu Huang, Hongxia Xue, Da Huang, Gang Qian, Junfa Hu, Xingxiang Chen, Tian Wang, Kehe Huang

Published Mar 1, 2016 · Vol. 7, No. 15 · pp. 20469-20485

Impact of molecular profiling on overall survival of patients with advanced ovarian cancer Research Paper

Thomas J. Herzog, David Spetzler, Nick Xiao, Ken Burnett, Todd Maney, Andreas Voss, Sandeep Reddy, Robert Burger, Thomas Krivak, Matthew Powell, Michael Friedlander, William McGuire

Published Mar 1, 2016 · Vol. 7, No. 15 · pp. 19840-19849

Long non-coding RNA containing ultraconserved genomic region 8 promotes bladder cancer tumorigenesis Research Paper

Michele Olivieri, Matteo Ferro, Sara Terreri, Montano Durso, Alessandra Romanelli, Concetta Avitabile, Ottavio De Cobelli, Anna Messere, Dario Bruzzese, Ivan Vannini, Luciana Marinelli, Ettore Novellino, Wei Zhang, Mariarosaria Incoronato, Gennaro Ilardi, Stefania Staibano, Laura Marra, Renato Franco, Sisto PerdonÃ, Daniela Terracciano, Bogdan Czerniak, Giovanna L. Liguori, Vincenza Colonna, Muller Fabbri, Ferdinando Febbraio, George A. Calin, Amelia Cimmino

Published Mar 1, 2016 · Vol. 7, No. 15 · pp. 20636-20654

High LEF1 expression predicts adverse prognosis in chronic lymphocytic leukemia and may be targeted by ethacrynic acid Research Paper

Wei Wu, Huayuan Zhu, Yuan Fu, Wenyi Shen, Kourong Miao, Min Hong, Wei Xu, Lei Fan, Ken H. Young, Peng Liu, Jianyong Li

Published Feb 29, 2016 · Vol. 7, No. 16 · pp. 21631-21643

Folic-acid metabolism and DNA-repair phenotypes differ between neuroendocrine lung tumors and associate with aggressive subtypes, therapy resistance and outcome Research Paper

Robert Fred Henry Walter, Fabian Dominik Mairinger, Robert Werner, Claudia Vollbrecht, Thomas Hager, Kurt Werner Schmid, Jeremias Wohlschlaeger, Daniel Christian Christoph

Published Feb 26, 2016 · Vol. 7, No. 15 · pp. 20166-20179

Publication Alerts

European Cancer and Oncology Congress

Post-Publication Promotion

Search Oncotarget

Reciprocal positive selection for weakness - preventing olaparib resistance by inhibiting BRCA2 Research Paper

Camptothecin targets WRN protein: mechanism and relevance in clinical breast cancer Priority Research Paper

The antihypertensive drug hydralazine activates the intrinsic pathway of apoptosis and causes DNA damage in leukemic T cells Research Paper

Prp19 facilitates invasion of hepatocellular carcinoma via p38 mitogen-activated protein kinase/Twist1 pathway Research Paper

Cinobufagin inhibits tumor growth by inducing intrinsic apoptosis through AKT signaling pathway in human nonsmall cell lung cancer cells Research Paper

Loss of p53-mediated cell-cycle arrest, senescence and apoptosis promotes genomic instability and premature aging Priority Research Paper

Common DNA methylation alterations of Alzheimerâ€™s disease and aging in peripheral whole blood Research Paper

Development of a novel HAC-based â€œgain of signalâ€ quantitative assay for measuring chromosome instability (CIN) in cancer cells Research Paper

Cancer therapeutic approach based on conformational stabilization of mutant p53 protein by small peptides Priority Research Paper

Repeated PM2.5 exposure inhibits BEAS-2B cell P53 expression through ROS-Akt-DNMT3B pathway-mediated promoter hypermethylation Research Paper

Tau accumulation impairs mitophagy via increasing mitochondrial membrane potential and reducing mitochondrial Parkin Research Paper

Ran Binding Protein 9 (RanBP9) is a novel mediator of cellular DNA damage response in lung cancer cells Research Paper

Smoking-promoted oxidative DNA damage response is highly correlated to lung carcinogenesis Research Paper

Alkaline ceramidase 2 and its bioactive product sphingosine are novel regulators of the DNA damage response Research Paper

BRAF and TERT promoter mutations in the aggressiveness of papillary thyroid carcinoma: a study of 653 patients Research Paper

Overexpression of pig selenoprotein S blocks OTA-induced promotion of PCV2 replication by inhibiting oxidative stress and p38 phosphorylation in PK15 cells Research Paper

Impact of molecular profiling on overall survival of patients with advanced ovarian cancer Research Paper

Long non-coding RNA containing ultraconserved genomic region 8 promotes bladder cancer tumorigenesis Research Paper

High LEF1 expression predicts adverse prognosis in chronic lymphocytic leukemia and may be targeted by ethacrynic acid Research Paper

Folic-acid metabolism and DNA-repair phenotypes differ between neuroendocrine lung tumors and associate with aggressive subtypes, therapy resistance and outcome Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Reciprocal positive selection for weakness - preventing olaparib resistance by inhibiting BRCA2 Research Paper

Camptothecin targets WRN protein: mechanism and relevance in clinical breast cancer Priority Research Paper

The antihypertensive drug hydralazine activates the intrinsic pathway of apoptosis and causes DNA damage in leukemic T cells Research Paper

Prp19 facilitates invasion of hepatocellular carcinoma via p38 mitogen-activated protein kinase/Twist1 pathway Research Paper

Cinobufagin inhibits tumor growth by inducing intrinsic apoptosis through AKT signaling pathway in human nonsmall cell lung cancer cells Research Paper

Loss of p53-mediated cell-cycle arrest, senescence and apoptosis promotes genomic instability and premature aging Priority Research Paper

Common DNA methylation alterations of Alzheimerâ€™s disease and aging in peripheral whole blood Research Paper

Development of a novel HAC-based â€œgain of signalâ€ quantitative assay for measuring chromosome instability (CIN) in cancer cells Research Paper

Cancer therapeutic approach based on conformational stabilization of mutant p53 protein by small peptides Priority Research Paper

Repeated PM2.5 exposure inhibits BEAS-2B cell P53 expression through ROS-Akt-DNMT3B pathway-mediated promoter hypermethylation Research Paper

Tau accumulation impairs mitophagy via increasing mitochondrial membrane potential and reducing mitochondrial Parkin Research Paper

Ran Binding Protein 9 (RanBP9) is a novel mediator of cellular DNA damage response in lung cancer cells Research Paper

Smoking-promoted oxidative DNA damage response is highly correlated to lung carcinogenesis Research Paper

Alkaline ceramidase 2 and its bioactive product sphingosine are novel regulators of the DNA damage response Research Paper

BRAF and TERT promoter mutations in the aggressiveness of papillary thyroid carcinoma: a study of 653 patients Research Paper

Overexpression of pig selenoprotein S blocks OTA-induced promotion of PCV2 replication by inhibiting oxidative stress and p38 phosphorylation in PK15 cells Research Paper

Impact of molecular profiling on overall survival of patients with advanced ovarian cancer Research Paper

Long non-coding RNA containing ultraconserved genomic region 8 promotes bladder cancer tumorigenesis Research Paper

High LEF1 expression predicts adverse prognosis in chronic lymphocytic leukemia and may be targeted by ethacrynic acid Research Paper

Folic-acid metabolism and DNA-repair phenotypes differ between neuroendocrine lung tumors and associate with aggressive subtypes, therapy resistance and outcome Research Paper

Development of a novel HAC-based â€œgain of signalâ€ quantitative assay for measuring chromosome instability (CIN) in cancer cells Research Paper