The Oncosearch | Oncotarget

Identification of a novel synthetic lethality of combined inhibition of hedgehog and PI3K signaling in rhabdomyosarcoma Research Paper

Ulrike Graab, Heidi Hahn, Simone Fulda

Published Mar 6, 2015 · Vol. 6, No. 11 · pp. 8722-8735

Keywords: apoptosis, hedgehog, PI3K, rhabdomyosarcoma

Biological rational for sequential targeting of Bruton tyrosine kinase and Bcl-2 to overcome CD40-induced ABT-199 resistance in mantle cell lymphoma Research Paper

David Chiron, Christelle Dousset, Carole Brosseau, Cyrille Touzeau, Sophie MaÃ¯ga, Philippe Moreau, Catherine Pellat-Deceunynck, Steven Le Gouill, Martine Amiot

Published Mar 5, 2015 · Vol. 6, No. 11 · pp. 8750-8759

Garcinol sensitizes human head and neck carcinoma to cisplatin in a xenograft mouse model despite downregulation of proliferative biomarkers Research Paper

Feng Li, Muthu K. Shanmugam, Kodappully Sivaraman Siveen, Fan Wang, Tina H. Ong, Ser Yue Loo, Mahadeva M.M. Swamy, Somnath Mandal, Alan Prem Kumar, Boon Cher Goh, Tapas Kundu, Kwang Seok Ahn, Ling Zhi Wang, Kam Man Hui, Gautam Sethi

Published Feb 28, 2015 · Vol. 6, No. 7 · pp. 5147-5163

Keywords: HNSCC, chemoresistance, NF-ÎºB, proliferation, garcinol.

Harnessing Noxa demethylation to overcome Bortezomib resistance in mantle cell lymphoma Research Paper

Violetta V. Leshchenko, Pei-Yu Kuo, Zewei Jiang, Marc A. Weniger, Jessica Overbey, Kieron Dunleavy, Wyndham H. Wilson, Adrian Wiestner, Samir Parekh

Published Feb 25, 2015 · Vol. 6, No. 29 · pp. 27332-27342

A transcriptomic signature mediated by HOXA9 promotes human glioblastoma initiation, aggressiveness and resistance to temozolomide Research Paper

Marta Pojo, CÃ©line S. GonÃ§alves, Ana Xavier-MagalhÃ£es, Ana Isabel Oliveira, Tiago GonÃ§alves, Sara Correia, Ana J. Rodrigues, Sandra Costa, LuÃsa Pinto, Afonso A. Pinto, JosÃ© M. Lopes, Rui M. Reis, Miguel Rocha, Nuno Sousa, Bruno M. Costa

Published Feb 20, 2015 · Vol. 6, No. 10 · pp. 7657-7674

Caffeic acid phenethyl ester induced cell cycle arrest and growth inhibition in androgen-independent prostate cancer cells via regulation of Skp2, p53, p21Cip1 and p27Kip1 Research Paper

Hui-Ping Lin, Ching-Yu Lin, Chieh Huo, Ping-Hsuan Hsiao, Liang-Cheng Su, Shih Sheng Jiang, Tzu-Min Chan, Chung-Ho Chang, Li-Tzong Chen, Hsing-Jien Kung, Horng-Dar Wang, Chih-Pin Chuu

Published Feb 16, 2015 · Vol. 6, No. 9 · pp. 6684-6707

Bcl-2 family proteins in breast development and cancer: could Mcl-1 targeting overcome therapeutic resistance? Review

Michelle M. Williams, Rebecca S. Cook

Published Feb 12, 2015 · Vol. 6, No. 6 · pp. 3519-3530

Synergistic anticancer effect of cisplatin and Chal-24 combination through IAP and c-FLIP_L degradation, Ripoptosome formation and autophagy-mediated apoptosis Research Paper

Shaoqing Shi, Qiong Wang, Jennings Xu, Jun-Ho Jang, Mabel T. Padilla, Toru Nyunoya, Chengguo Xing, Lin Zhang, Yong Lin

Published Feb 12, 2015 · Vol. 6, No. 3 · pp. 1640-1651

Keywords: autophagy, apoptosis, c-IAP, c-FLIP, cisplatin, Chal-24

Targeting argininosuccinate synthetase negative melanomas using combination of arginine degrading enzyme and cisplatin Research Paper

Niramol Savaraj, Chunjing Wu, Ying-Ying Li, Medhi Wangpaichitr, Min You, John Bomalaski, Wei He, Macus Tien Kuo, Lynn G. Feun

Published Jan 31, 2015 · Vol. 6, No. 8 · pp. 6295-6309

Oncogenes and tumor suppressor genes in squamous cell carcinoma of the tongue in young patients Clinical Research Papers

Andreas Knopf, Justine Lempart, Murat Bas, Julia Slotta-Huspenina, Naglaa Mansour, Marie Kristin Fritsche

Published Jan 30, 2015 · Vol. 6, No. 5 · pp. 3443-3451

Bee venom inhibits growth of human cervical tumors in mice Research Paper

Hye Lim Lee, Sang Ho Park, Tae Myoung Kim, Yu Yeon Jung, Mi Hee Park, Sang Hyun Oh, Hye Seok Yun, Hyung Ok Jun, Hwan Soo Yoo, Sang-Bae Han, Ung Soo Lee, Joo Hee Yoon, Min Jong Song, Jin Tae Hong

Published Jan 23, 2015 · Vol. 6, No. 9 · pp. 7280-7292

Carnosic acid sensitized TRAIL-mediated apoptosis through down-regulation of c-FLIP and Bcl-2 expression at the post translational levels and CHOP-dependent up-regulation of DR5, Bim, and PUMA expression in human carcinoma caki cells Research Paper

Kyong-Jin Jung, Kyoung-Jin Min, Jae Hoon Bae, Taeg Kyu Kwon

Published Jan 22, 2015 · Vol. 6, No. 3 · pp. 1556-1568

Keywords: Carnosic acid, TRAIL, Bcl-2, c-FLIP, CHOP

Dysregulated CXCR4 expression promotes lymphoma cell survival and independently predicts disease progression in germinal center B-cell-like diffuse large B-cell lymphoma Research Paper

Jiayu Chen, Zijun Y. Xu-Monette, Lijuan Deng, Qi Shen, Ganiraju C. Manyam, Azahara Martinez-Lopez, Li Zhang, Santiago Montes-Moreno, Carlo Visco, Alexandar Tzankov, Lihui Yin, Karen Dybkaer, April Chiu, Attilio Orazi, Youli Zu, Govind Bhagat, Kristy L. Richards, Eric D. Hsi, William W.L. Choi, J. Han van Krieken, Jooryung Huh, Maurilio Ponzoni, AndrÃ©s J.M. Ferreri, Xiaoying Zhao, Michael B. MÃ¸ller, John P. Farnen, Jane N. Winter, Miguel A. Piris, Lan Pham, Ken H. Young

Published Jan 21, 2015 · Vol. 6, No. 8 · pp. 5597-5614

Dihydroartemisinin and its derivative induce apoptosis in acute myeloid leukemia through Noxa-mediated pathway requiring iron and endoperoxide moiety Research Paper

Xuan Zhao, Hang Zhong, Rui Wang, Dan Liu, Samuel Waxman, Linxiang Zhao, Yongkui Jing

Published Jan 21, 2015 · Vol. 6, No. 8 · pp. 5582-5596

Mechanistic rationale for MCL1 inhibition during androgen deprivation therapy Research Paper

FrÃ©dÃ©ric R. Santer, Holger H. H. Erb, Su Jung Oh, Florian Handle, Gertrud E. Feiersinger, Birgit Luef, Huajie Bu, Georg SchÃ¤fer, Christian Ploner, Martina Egger, Jayant K. Rane, Norman J. Maitland, Helmut Klocker, Iris E. Eder, Zoran Culig

Published Jan 14, 2015 · Vol. 6, No. 8 · pp. 6105-6122

Folate-mediated mitochondrial targeting with doxorubicin-polyrotaxane nanoparticles overcomes multidrug resistance Research Paper

He Wang, Henghui Yin, Fengjiao Yan, Mingna Sun, Lingran Du, Wei Peng, Qiuli Li, Yinghong Feng, Yi Zhou

Published Dec 30, 2014 · Vol. 6, No. 5 · pp. 2827-2842

A role for BMP-induced homeobox gene MIXL1 in acute myelogenous leukemia and identification of type I BMP receptor as a potential target for therapy Research Paper

Aaron Raymond, Bin Liu, Hong Liang, Ciamaio Wei, Michele Guindani, Yue Lu, Shoudan Liang, Lisa S. St. John, Jeff Molldrem, Lalitha Nagarajan

Published Dec 17, 2014 · Vol. 5, No. 24 · pp. 12675-12693

Silencing of CXCR4 sensitizes triple-negative breast cancer cells to cisplatin Research Paper

Sixian Liang, Xun Peng, Xiaoli Li, Ping Yang, Linhao Xie, Yaochen Li, Caiwen Du, Guojun Zhang

Published Dec 11, 2014 · Vol. 6, No. 2 · pp. 1020-1030

Keywords: CXCR4, triple-negative breast cancer, cisplatin, chemosensitivity, apoptosis

NEK2 mediates ALDH1A1-dependent drug resistance in multiple myeloma Research Paper

Ye Yang, Wen Zhou, Jiliang Xia, Zhimin Gu, Erik Wendlandt, Xin Zhan, Siegfried Janz, Guido Tricot, Fenghuang Zhan

Published Dec 9, 2014 · Vol. 5, No. 23 · pp. 11986-11997

STAT3 inhibition suppresses proliferation of retinoblastoma through down-regulation of positive feedback loop of STAT3/miR-17-92 clusters Research Paper

Dong Hyun Jo, Jin Hyoung Kim, Chang Sik Cho, Young-Lai Cho, Hyoung Oh Jun, Young Suk Yu, Jeong-Ki Min, Jeong Hun Kim

Published Nov 3, 2014 · Vol. 5, No. 22 · pp. 11513-11525

Keywords: Retinoblastoma, STAT3 transcription factor, miR-17-92

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Identification of a novel synthetic lethality of combined inhibition of hedgehog and PI3K signaling in rhabdomyosarcoma Research Paper

Biological rational for sequential targeting of Bruton tyrosine kinase and Bcl-2 to overcome CD40-induced ABT-199 resistance in mantle cell lymphoma Research Paper

Garcinol sensitizes human head and neck carcinoma to cisplatin in a xenograft mouse model despite downregulation of proliferative biomarkers Research Paper

Harnessing Noxa demethylation to overcome Bortezomib resistance in mantle cell lymphoma Research Paper

A transcriptomic signature mediated by HOXA9 promotes human glioblastoma initiation, aggressiveness and resistance to temozolomide Research Paper

Caffeic acid phenethyl ester induced cell cycle arrest and growth inhibition in androgen-independent prostate cancer cells via regulation of Skp2, p53, p21Cip1 and p27Kip1 Research Paper

Bcl-2 family proteins in breast development and cancer: could Mcl-1 targeting overcome therapeutic resistance? Review

Synergistic anticancer effect of cisplatin and Chal-24 combination through IAP and c-FLIP_L degradation, Ripoptosome formation and autophagy-mediated apoptosis Research Paper

Targeting argininosuccinate synthetase negative melanomas using combination of arginine degrading enzyme and cisplatin Research Paper

Oncogenes and tumor suppressor genes in squamous cell carcinoma of the tongue in young patients Clinical Research Papers

Bee venom inhibits growth of human cervical tumors in mice Research Paper

Carnosic acid sensitized TRAIL-mediated apoptosis through down-regulation of c-FLIP and Bcl-2 expression at the post translational levels and CHOP-dependent up-regulation of DR5, Bim, and PUMA expression in human carcinoma caki cells Research Paper

Dysregulated CXCR4 expression promotes lymphoma cell survival and independently predicts disease progression in germinal center B-cell-like diffuse large B-cell lymphoma Research Paper

Dihydroartemisinin and its derivative induce apoptosis in acute myeloid leukemia through Noxa-mediated pathway requiring iron and endoperoxide moiety Research Paper

Mechanistic rationale for MCL1 inhibition during androgen deprivation therapy Research Paper

Folate-mediated mitochondrial targeting with doxorubicin-polyrotaxane nanoparticles overcomes multidrug resistance Research Paper

A role for BMP-induced homeobox gene MIXL1 in acute myelogenous leukemia and identification of type I BMP receptor as a potential target for therapy Research Paper

Silencing of CXCR4 sensitizes triple-negative breast cancer cells to cisplatin Research Paper

NEK2 mediates ALDH1A1-dependent drug resistance in multiple myeloma Research Paper

STAT3 inhibition suppresses proliferation of retinoblastoma through down-regulation of positive feedback loop of STAT3/miR-17-92 clusters Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Identification of a novel synthetic lethality of combined inhibition of hedgehog and PI3K signaling in rhabdomyosarcoma Research Paper

Biological rational for sequential targeting of Bruton tyrosine kinase and Bcl-2 to overcome CD40-induced ABT-199 resistance in mantle cell lymphoma Research Paper

Garcinol sensitizes human head and neck carcinoma to cisplatin in a xenograft mouse model despite downregulation of proliferative biomarkers Research Paper

Harnessing Noxa demethylation to overcome Bortezomib resistance in mantle cell lymphoma Research Paper

A transcriptomic signature mediated by HOXA9 promotes human glioblastoma initiation, aggressiveness and resistance to temozolomide Research Paper

Caffeic acid phenethyl ester induced cell cycle arrest and growth inhibition in androgen-independent prostate cancer cells via regulation of Skp2, p53, p21Cip1 and p27Kip1 Research Paper

Bcl-2 family proteins in breast development and cancer: could Mcl-1 targeting overcome therapeutic resistance? Review

Synergistic anticancer effect of cisplatin and Chal-24 combination through IAP and c-FLIPL degradation, Ripoptosome formation and autophagy-mediated apoptosis Research Paper

Targeting argininosuccinate synthetase negative melanomas using combination of arginine degrading enzyme and cisplatin Research Paper

Oncogenes and tumor suppressor genes in squamous cell carcinoma of the tongue in young patients Clinical Research Papers

Bee venom inhibits growth of human cervical tumors in mice Research Paper

Carnosic acid sensitized TRAIL-mediated apoptosis through down-regulation of c-FLIP and Bcl-2 expression at the post translational levels and CHOP-dependent up-regulation of DR5, Bim, and PUMA expression in human carcinoma caki cells Research Paper

Dysregulated CXCR4 expression promotes lymphoma cell survival and independently predicts disease progression in germinal center B-cell-like diffuse large B-cell lymphoma Research Paper

Dihydroartemisinin and its derivative induce apoptosis in acute myeloid leukemia through Noxa-mediated pathway requiring iron and endoperoxide moiety Research Paper

Mechanistic rationale for MCL1 inhibition during androgen deprivation therapy Research Paper

Folate-mediated mitochondrial targeting with doxorubicin-polyrotaxane nanoparticles overcomes multidrug resistance Research Paper

A role for BMP-induced homeobox gene MIXL1 in acute myelogenous leukemia and identification of type I BMP receptor as a potential target for therapy Research Paper

Silencing of CXCR4 sensitizes triple-negative breast cancer cells to cisplatin Research Paper

NEK2 mediates ALDH1A1-dependent drug resistance in multiple myeloma Research Paper

STAT3 inhibition suppresses proliferation of retinoblastoma through down-regulation of positive feedback loop of STAT3/miR-17-92 clusters Research Paper

Synergistic anticancer effect of cisplatin and Chal-24 combination through IAP and c-FLIP_L degradation, Ripoptosome formation and autophagy-mediated apoptosis Research Paper