The Oncosearch | Oncotarget

TQ inhibits hepatocellular carcinoma growth in vitro and in vivo via repression of Notch signaling Research Paper

Xiquan Ke, Yan Zhao, Xinlan Lu, Zhe Wang, Yuanyuan Liu, Mudan Ren, Guifang Lu, Dan Zhang, Zhenguo Sun, Zhipeng Xu, Jee Hoon Song, Yulan Cheng, Stephen J. Meltzer, Shuixiang He

Published Sep 21, 2015 · Vol. 6, No. 32 · pp. 32610-32621

Co-targeting of Bcl-2 and mTOR pathway triggers synergistic apoptosis in BH3 mimetics resistant acute lymphoblastic leukemia Research Paper

Stefano Iacovelli, Maria Rosaria Ricciardi, Matteo Allegretti, Simone Mirabilii, Roberto Licchetta, Paola Bergamo, Cinzia Rinaldo, Ann Zeuner, Robin FoÃ, Michele Milella, James A. McCubrey, Alberto M. Martelli, Agostino Tafuri

Published Sep 16, 2015 · Vol. 6, No. 31 · pp. 32089-32103

Valproic acid enhances the efficacy of radiation therapy by protecting normal hippocampal neurons and sensitizing malignant glioblastoma cells Research Paper

Dinesh Thotala, Rowan M. Karvas, John A. Engelbach, Joel R. Garbow, Andrew N. Hallahan, Todd A. DeWees, Andrei Laszlo, Dennis E. Hallahan

Published Sep 16, 2015 · Vol. 6, No. 33 · pp. 35004-35022

E2F7 overexpression leads to tamoxifen resistance in breast cancer cells by competing with E2F1 at miR-15a/16 promoter Research Paper

Junjun Chu, Yinghua Zhu, Yujie Liu, Lijuan Sun, Xiaobin Lv, Yanqin Wu, Pengnan Hu, Fengxi Su, Chang Gong, Erwei Song, Bodu Liu, Qiang Liu

Published Sep 12, 2015 · Vol. 6, No. 31 · pp. 31944-31957

The hypomethylating agent decitabine prior to chemotherapy improves the therapy efficacy in refractory/relapsed acute myeloid leukemia patients Research Paper

Xuejie Jiang, Zhixiang Wang, Bingjie Ding, Changxin Yin, Qingxiu Zhong, Bing Z. Carter, Guopan Yu, Ling Jiang, Jieyu Ye, Min Dai, Yu Zhang, Shuang Liang, Qingxia Zhao, Qifa Liu, Fanyi Meng

Published Sep 10, 2015 · Vol. 6, No. 32 · pp. 33612-33622

The oncolytic peptide LTX-315 kills cancer cells through Bax/Bak-regulated mitochondrial membrane permeabilization Priority Research Paper

Heng Zhou, Sabrina Forveille, Allan Sauvat, Valentina Sica, Valentina Izzo, SylvÃ¨re Durand, Kevin MÃ¼ller, Peng Liu, Laurence Zitvogel, Ã˜ystein Rekdal, Oliver Kepp, Guido Kroemer

Published Sep 10, 2015 · Vol. 6, No. 29 · pp. 26599-26614

B5, a thioredoxin reductase inhibitor, induces apoptosis in human cervical cancer cells by suppressing the thioredoxin system, disrupting mitochondrion-dependent pathways and triggering autophagy Research Paper

Fang-Yuan Shao, Zhi-Yun Du, Dong-Lei Ma, Wen-Bo Chen, Wu-Yu Fu, Bi-Bo Ruan, Wen Rui, Jia-Xuan Zhang, Sheng Wang, Nai Sum Wong, Hao Xiao, Man-Mei Li, Xiao Liu, Qiu-Ying Liu, Xiao-dong Zhou, Hai-Zhao Yan, Yi-Fei Wang, Chang-Yan Chen, Zhong Liu, Hong-Yuan Chen

Published Sep 4, 2015 · Vol. 6, No. 31 · pp. 30939-30956

URGCP/URG4 promotes apoptotic resistance in bladder cancer cells by activating NF-κB signaling Research Paper

Minglong Wu, Junxing Chen, Yuxi Wang, Jinqian Hu, Chang Liu, Chunxiang Feng, Xiaoyong Zeng

Published Sep 2, 2015 · Vol. 6, No. 31 · pp. 30887-30901

Stat5-deficient hematopoiesis is permissive for Myc-induced B-cell leukemogenesis Research Paper

Zhengqi Wang, Magdalena Medrzycki, Silvia T. Bunting, Kevin D. Bunting

Published Aug 22, 2015 · Vol. 6, No. 30 · pp. 28961-28972

Clinical impact of CD200 expression in patients with acute myeloid leukemia and correlation with other molecular prognostic factors Research Paper

Daniela Damiani, Mario Tiribelli, Donatella Raspadori, Santina Sirianni, Alessia Meneghel, Margherita Cavalllin, Angela Michelutti, Eleonora Toffoletti, Antonella Geromin, Erica Simeone, Monica Bocchia, Renato Fanin

Published Aug 18, 2015 · Vol. 6, No. 30 · pp. 30212-30221

Cyclooxygenase-2 in tumor-associated macrophages promotes breast cancer cell survival by triggering a positive-feedback loop between macrophages and cancer cells Research Paper

Hongzhong Li, Bing Yang, Jing Huang, Yong Lin, Tingxiu Xiang, Jingyuan Wan, Hongyuan Li, Salem Chouaib, Guosheng Ren

Published Aug 10, 2015 · Vol. 6, No. 30 · pp. 29637-29650

A novel small-molecule IAP antagonist, AZD5582, draws Mcl-1 down-regulation for induction of apoptosis through targeting of cIAP1 and XIAP in human pancreatic cancer Research Paper

Jai-Hee Moon, Jae-Sik Shin, Seung-Woo Hong, Soo-A Jung, Ih-Yeon Hwang, Jeong Hee Kim, Eun Kyoung Choi, Seung-Hee Ha, Jin-Sun Kim, Kyoung-Mok Kim, Dae-Won Hong, Daejin Kim, Yeong Seok Kim, Jeong Eun Kim, Kyu-Pyo Kim, Yong Sang Hong, Eun Kyung Choi, Jung Shin Lee, Maureen Hattersley, Dong-Hoon Jin, Tae Won Kim

Published Aug 6, 2015 · Vol. 6, No. 29 · pp. 26895-26908

Fisetin, a phytochemical, potentiates sorafenib-induced apoptosis and abrogates tumor growth in athymic nude mice implanted with BRAF-mutated melanoma cells Research Paper

Harish Chandra Pal, Ronald D. Baxter, Katherine M. Hunt, Jyoti Agarwal, Craig A. Elmets, Mohammad Athar, Farrukh Afaq

Published Jul 31, 2015 · Vol. 6, No. 29 · pp. 28296-28311

Licochalcone A induces autophagy through PI3K/Akt/mTOR inactivation and autophagy suppression enhances Licochalcone A-induced apoptosis of human cervical cancer cells Research Paper

Jen-Pi Tsai, Chien-Hsing Lee, Tsung-Ho Ying, Chu-Liang Lin, Chia-Liang Lin, Jung-Tsung Hsueh, Yi-Hsien Hsieh

Published Jul 31, 2015 · Vol. 6, No. 30 · pp. 28851-28866

RY-2f, an isoflavone analog, overcomes cisplatin resistance to inhibit ovarian tumorigenesis via targeting the PI3K/AKT/mTOR signaling pathway Research Paper

Mingming Liu, Zihao Qi, Bingzhi Liu, Yi Ren, Hanbin Li, Gong Yang, Qian Zhang

Published Jul 30, 2015 · Vol. 6, No. 28 · pp. 25281-25294

IL-6 signaling contributes to cisplatin resistance in non-small cell lung cancer via the up-regulation of anti-apoptotic and DNA repair associated molecules Research Paper

Shanzhou Duan, Ying Tsai, Peter Keng, Yongbing Chen, Soo Ok Lee, Yuhchyau Chen

Published Jul 30, 2015 · Vol. 6, No. 29 · pp. 27651-27660

Inhibition of microRNA-497 ameliorates anoxia/reoxygenation injury in cardiomyocytes by suppressing cell apoptosis and enhancing autophagy Research Paper

Xixian Li, Zhi Zeng, Qingman Li, Qiulin Xu, Jiahe Xie, Huixin Hao, Guangjin Luo, Wangjun Liao, Jianping Bin, Xiaobo Huang, Yulin Liao

Published Jul 29, 2015 · Vol. 6, No. 22 · pp. 18829-18844

The BIM deletion polymorphism is a prognostic biomarker of EGFR-TKIs response in NSCLC: A systematic review and meta-analysis Research Paper

Wei Nie, Xia Tao, Hua Wei, Wan-sheng Chen, Bing Li

Published Jul 27, 2015 · Vol. 6, No. 28 · pp. 25696-25700

Down-regulation of c-Met and Bcl2 by microRNA-206, activates apoptosis, and inhibits tumor cell proliferation, migration and colony formation Research Paper

Chengcao Sun, Shujun Li, Cuili Yang, Ruilin Xue, Yongyong Xi, Liang Wang, Suqing Wang, Qiqiang He, Jie Huang, Songping Xie, Wenyang Jiang, Dejia Li

Published Jul 25, 2015 · Vol. 6, No. 28 · pp. 25533-25574

ABT-263 induces apoptosis and synergizes with chemotherapy by targeting stemness pathways in esophageal cancer Research Paper

Qiongrong Chen, Shumei Song, Shaozhong Wei, Bin Liu, Soichiro Honjo, Ailing Scott, Jiankang Jin, Lang Ma, Haitao Zhu, Heath D. Skinner, Randy L. Johnson, Jaffer A. Ajani

Published Jul 17, 2015 · Vol. 6, No. 28 · pp. 25883-25896

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TQ inhibits hepatocellular carcinoma growth in vitro and in vivo via repression of Notch signaling Research Paper

Co-targeting of Bcl-2 and mTOR pathway triggers synergistic apoptosis in BH3 mimetics resistant acute lymphoblastic leukemia Research Paper

Valproic acid enhances the efficacy of radiation therapy by protecting normal hippocampal neurons and sensitizing malignant glioblastoma cells Research Paper

E2F7 overexpression leads to tamoxifen resistance in breast cancer cells by competing with E2F1 at miR-15a/16 promoter Research Paper

The hypomethylating agent decitabine prior to chemotherapy improves the therapy efficacy in refractory/relapsed acute myeloid leukemia patients Research Paper

The oncolytic peptide LTX-315 kills cancer cells through Bax/Bak-regulated mitochondrial membrane permeabilization Priority Research Paper

B5, a thioredoxin reductase inhibitor, induces apoptosis in human cervical cancer cells by suppressing the thioredoxin system, disrupting mitochondrion-dependent pathways and triggering autophagy Research Paper

URGCP/URG4 promotes apoptotic resistance in bladder cancer cells by activating NF-κB signaling Research Paper

Stat5-deficient hematopoiesis is permissive for Myc-induced B-cell leukemogenesis Research Paper

Clinical impact of CD200 expression in patients with acute myeloid leukemia and correlation with other molecular prognostic factors Research Paper

Cyclooxygenase-2 in tumor-associated macrophages promotes breast cancer cell survival by triggering a positive-feedback loop between macrophages and cancer cells Research Paper

A novel small-molecule IAP antagonist, AZD5582, draws Mcl-1 down-regulation for induction of apoptosis through targeting of cIAP1 and XIAP in human pancreatic cancer Research Paper

Fisetin, a phytochemical, potentiates sorafenib-induced apoptosis and abrogates tumor growth in athymic nude mice implanted with BRAF-mutated melanoma cells Research Paper

Licochalcone A induces autophagy through PI3K/Akt/mTOR inactivation and autophagy suppression enhances Licochalcone A-induced apoptosis of human cervical cancer cells Research Paper

RY-2f, an isoflavone analog, overcomes cisplatin resistance to inhibit ovarian tumorigenesis via targeting the PI3K/AKT/mTOR signaling pathway Research Paper

IL-6 signaling contributes to cisplatin resistance in non-small cell lung cancer via the up-regulation of anti-apoptotic and DNA repair associated molecules Research Paper

Inhibition of microRNA-497 ameliorates anoxia/reoxygenation injury in cardiomyocytes by suppressing cell apoptosis and enhancing autophagy Research Paper

The BIM deletion polymorphism is a prognostic biomarker of EGFR-TKIs response in NSCLC: A systematic review and meta-analysis Research Paper

Down-regulation of c-Met and Bcl2 by microRNA-206, activates apoptosis, and inhibits tumor cell proliferation, migration and colony formation Research Paper

ABT-263 induces apoptosis and synergizes with chemotherapy by targeting stemness pathways in esophageal cancer Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

TQ inhibits hepatocellular carcinoma growth in vitro and in vivo via repression of Notch signaling Research Paper

Co-targeting of Bcl-2 and mTOR pathway triggers synergistic apoptosis in BH3 mimetics resistant acute lymphoblastic leukemia Research Paper

Valproic acid enhances the efficacy of radiation therapy by protecting normal hippocampal neurons and sensitizing malignant glioblastoma cells Research Paper

E2F7 overexpression leads to tamoxifen resistance in breast cancer cells by competing with E2F1 at miR-15a/16 promoter Research Paper

The hypomethylating agent decitabine prior to chemotherapy improves the therapy efficacy in refractory/relapsed acute myeloid leukemia patients Research Paper

The oncolytic peptide LTX-315 kills cancer cells through Bax/Bak-regulated mitochondrial membrane permeabilization Priority Research Paper

B5, a thioredoxin reductase inhibitor, induces apoptosis in human cervical cancer cells by suppressing the thioredoxin system, disrupting mitochondrion-dependent pathways and triggering autophagy Research Paper

URGCP/URG4 promotes apoptotic resistance in bladder cancer cells by activating NF-κB signaling Research Paper

Stat5-deficient hematopoiesis is permissive for Myc-induced B-cell leukemogenesis Research Paper

Clinical impact of CD200 expression in patients with acute myeloid leukemia and correlation with other molecular prognostic factors Research Paper

Cyclooxygenase-2 in tumor-associated macrophages promotes breast cancer cell survival by triggering a positive-feedback loop between macrophages and cancer cells Research Paper

A novel small-molecule IAP antagonist, AZD5582, draws Mcl-1 down-regulation for induction of apoptosis through targeting of cIAP1 and XIAP in human pancreatic cancer Research Paper

Fisetin, a phytochemical, potentiates sorafenib-induced apoptosis and abrogates tumor growth in athymic nude mice implanted with BRAF-mutated melanoma cells Research Paper

Licochalcone A induces autophagy through PI3K/Akt/mTOR inactivation and autophagy suppression enhances Licochalcone A-induced apoptosis of human cervical cancer cells Research Paper

RY-2f, an isoflavone analog, overcomes cisplatin resistance to inhibit ovarian tumorigenesis via targeting the PI3K/AKT/mTOR signaling pathway Research Paper

IL-6 signaling contributes to cisplatin resistance in non-small cell lung cancer via the up-regulation of anti-apoptotic and DNA repair associated molecules Research Paper

Inhibition of microRNA-497 ameliorates anoxia/reoxygenation injury in cardiomyocytes by suppressing cell apoptosis and enhancing autophagy Research Paper

The BIM deletion polymorphism is a prognostic biomarker of EGFR-TKIs response in NSCLC: A systematic review and meta-analysis Research Paper

Down-regulation of c-Met and Bcl2 by microRNA-206, activates apoptosis, and inhibits tumor cell proliferation, migration and colony formation Research Paper

ABT-263 induces apoptosis and synergizes with chemotherapy by targeting stemness pathways in esophageal cancer Research Paper