The Oncosearch | Oncotarget

Aberrant epigenetic silencing of neuronatin is a frequent event in human osteosarcoma Research Paper

Haleema Saeed, Sayantani Sinha, Christine Mella, Jeffrey S. Kuerbitz, Monica L. Cales, Mark A. Steele, Jennifer Stanke, Derek Damron, Fayez Safadi, Steven J. Kuerbitz

Published Apr 22, 2020

Keywords: osteosarcoma, DNA methylation, neuronatin, tumor suppressor genes

Expression of Nrf2 and NF-κB transcription factors in breast cancer and breast fibroadenoma: Insights for a new therapeutic approach Research Paper

Camila Maria Simplicio-Revoredo, Renato de Oliveira Pereira, Mariella de Almeida Melo, Pedro Vitor Lopes-Costa, Paulo de Tarso Moura-Borges, Emerson Brandão Sousa, Fidelis Manes Neto, Viriato Campelo, Ione Maria Ribeiro Soares-Lopes, Maria da Conceição Barros-Oliveira, Cleciton Braga Tavares, Alesse Ribeiro dos Santos, Camila Guedes Borges de Araújo, Eid Gonçalves Coelho, Larysse Cardoso Campos-Verdes, Aldenora Oliveira do Nascimento-Holanda, Jackeline Lopes Viana, Maria Liduina Meneses Bezerra-Chaves, Rodrigo José de Vasconcelos-Valença, Lina Gomes dos Santos, Lauro Rodolpho Soares-Lopes, André Luiz Pinho-Sobral, Luiz Henrique Gebrim, Benedito Borges da Silva

Published Apr 18, 2020 · Vol. 11, No. 18 · pp. 1629-1636

Keywords: breast cancer, fibroadenoma, NRF2, NF-κB, immunohistochemistry

Correction: Frankincense essential oil suppresses melanoma cancer through down regulation of Bcl-2/Bax cascade signaling and ameliorates heptotoxicity via phase I and II drug metabolizing enzymes Correction

Faruck L. Hakkim, Hamid A. Bakshi, Shabia Khan, Mohamed M. Nasef, Rabia Farzand, Smitha Sam, Luay Rashan, Mohammed S. Al-Baloshi, Sidgi Syed Anwar Abdo Hasson, Ali Al Jabri, Paul A. McCarron, Murtaza M. Tambuwala

Published Mar 23, 2020 · Vol. 11, No. 23 · pp. 2259-2261

The anti-tumor activity of pralatrexate (PDX) correlates with the expression of RFC and DHFR mRNA in preclinical models of multiple myeloma Research Paper

Cristina Kinahan, Michael A. Mangone, Luigi Scotto, Michele Visentin, Enrica Marchi, Hearn Jay Cho, Owen A. O’Connor

Published Feb 26, 2020 · Vol. 11, No. 18 · pp. 1576-1589

Keywords: antifolate, multiple myeloma, pralatrexate, biomarker, reduced folate carrier (RFC)

The anti-tumor activity of pralatrexate (PDX) correlates with the expression of RFC and DHFR mRNA in preclinical models of multiple myeloma Research Paper

Cristina Kinahan, Michael A. Mangone, Luigi Scotto, Michele Visentin, Enrica Marchi, Hearn Jay Cho, Owen A. O’Connor

Published Feb 26, 2020

Keywords: antifolate, multiple myeloma, pralatrexate, biomarker, reduced folate carrier (RFC)

The anti-tumor activity of pralatrexate (PDX) correlates with the expression of RFC and DHFR mRNA in preclinical models of multiple myeloma Research Paper

Cristina Kinahan, Michael A. Mangone, Luigi Scotto, Michele Visentin, Enrica Marchi, Hearn Jay Cho, Owen A. O’Connor

Published Feb 26, 2020

Keywords: antifolate, multiple myeloma, pralatrexate, biomarker, reduced folate carrier (RFC)

DNA dependent protein kinase (DNA-PK) enhances HIV transcription by promoting RNA polymerase II activity and recruitment of transcription machinery at HIV LTR Research Paper

Sonia Zicari, Adhikarimayum Lakhikumar Sharma, Geetaram Sahu, Larisa Dubrovsky, Lin Sun, Han Yue, Tejaswi Jada, Alex Ochem, Gary Simon, Michael Bukrinsky, Mudit Tyagi

Published Feb 18, 2020 · Vol. 11, No. 7 · pp. 699-726

Keywords: HIV, DNA-PK, transcription, replication, DNA-PK inhibitors

The synergistic inhibitory effect of combining therapies targeting EGFR and mitochondria in sarcomas Research Paper

Xiaochun Wang, Reichelle X. Yeo, Philip J. Hogg, David Goldstein, Philip Crowe, Pierre J. Dilda, Jia-Lin Yang

Published Jan 7, 2020 · Vol. 11, No. 1 · pp. 46-61

Keywords: EGFR-targeted therapy, mitochondria inhibitor, tumour metabolism inhibition, sarcomas, combination therapy

Reactive oxygen/nitrogen species contribute substantially to the antileukemia effect of APO866, a NAD lowering agent Research Paper

Anne-Julie Cloux, Dominique Aubry, Mathieu Heulot, Christian Widmann, Oussama ElMokh, Francesco Piacente, Michele Cea, Alessio Nencioni, Axel Bellotti, Karima Bouzourène, Maxime Pellegrin, Lucia Mazzolai, Michel A. Duchosal, Aimable Nahimana

Published Nov 19, 2019 · Vol. 10, No. 62 · pp. 6723-6738

Keywords: tumor cell death, parthanatos, non-apoptotic death, APO866/FK866, NAD

Dynamic transition of the blood-brain barrier in the development of non-small cell lung cancer brain metastases Research Paper

Gozde Uzunalli, Alexandra M. Dieterly, Chinyere M. Kemet, Hsin-Yi Weng, Arvin H. Soepriatna, Craig J. Goergen, Aparna B. Shinde, Michael K. Wendt, L. Tiffany Lyle

Published Oct 29, 2019 · Vol. 10, No. 59 · pp. 6334-6348

Keywords: blood-brain barrier, blood-tumor barrier, non-small cell lung cancer, brain metastasis, aquaporin-4

Effect of Fms-like tyrosine kinase 3 (FLT3) ligand (FL) on antitumor activity of gilteritinib, a FLT3 inhibitor, in mice xenografted with FL-overexpressing cells Research Paper

Tatsuya Kawase, Taisuke Nakazawa, Tomohiro Eguchi, Hirofumi Tsuzuki, Yoko Ueno, Yasushi Amano, Tomoyuki Suzuki, Masamichi Mori, Taku Yoshida

Published Oct 22, 2019 · Vol. 10, No. 58 · pp. 6111-6123

Keywords: FLT3, FL, FLT3 inhibitor, gilteritinib, antitumor activity

Targeting glutaminase1 and synergizing with clinical drugs achieved more promising antitumor activity on multiple myeloma Research Paper

Qiang Qiu, Mengyuan Li, Linyu Yang, Minghai Tang, Li Zheng, Fang Wang, Huandi Qiu, Cailing Liang, Ning Li, Dongni Yi, Yuyao Yi, Cong Pan, Shengyong Yang, Lijuan Chen, Yiguo Hu

Published Oct 15, 2019 · Vol. 10, No. 57 · pp. 5993-6005

Keywords: glutaminase1, multiple myeloma, BPTES, cMYC/KRAS12V-transduced plasmacytoma, mouse model

Mechanisms by which PE21, an extract from the white willow Salix alba, delays chronological aging in budding yeast Research Paper

Younes Medkour, Karamat Mohammad, Anthony Arlia-Ciommo, Veronika Svistkova, Pamela Dakik, Darya Mitrofanova, Monica Enith Lozano Rodriguez, Jennifer Anne Baratang Junio, Tarek Taifour, Paola Escudero, Fani-Fay Goltsios, Sahar Soodbakhsh, Hana Maalaoui, Éric Simard, Vladimir I. Titorenko

Published Oct 8, 2019 · Vol. 10, No. 56 · pp. 5780-5816

Keywords: cellular aging, geroprotectors, lipid metabolism, necrotic cell death, mitochondria

Correction: Metformin sensitizes anticancer effect of dasatinib in head and neck squamous cell carcinoma cells through AMPK-dependent ER stress Correction

Yu-Chin Lin, Meng-Hsuan Wu, Tzu-Tang Wei, Yun-Chieh Lin, Wen-Chih Huang, Liang-Yu Huang, Yi-Ting Lin, Ching-Chow Chen

Published Sep 26, 2019 · Vol. 10, No. 55 · pp. 5724-5725

Dual-Targeting AKT2 and ERK in cancer stem-like cells in neuroblastoma Research Paper

Kwang Woon Kim, Julia Y. Kim, Jingbo Qiao, Rachael A. Clark, Camille M. Powers, Hernan Correa, Dai H. Chung

Published Sep 24, 2019 · Vol. 10, No. 54 · pp. 5645-5659

Keywords: chemotherapy, radiotherapy, resistance, AKT2, MAPK

Dual-Targeting AKT2 and ERK in cancer stem-like cells in neuroblastoma Research Paper

Kwang Woon Kim, Julia Y. Kim, Jingbo Qiao, Rachael A. Clark, Camille M. Powers, Hernan Correa, Dai H. Chung

Published Sep 5, 2019

Keywords: chemotherapy, radiotherapy, resistance, AKT2, MAPK

Mechanisms by which PE21, an extract from the white willow Salix alba, delays chronological aging in budding yeast Research Paper

Younes Medkour, Karamat Mohammad, Anthony Arlia-Ciommo, Veronika Svistkova, Pamela Dakik, Darya Mitrofanova, Monica Enith Lozano Rodriguez, Jennifer Anne Baratang Junio, Tarek Taifour, Paola Escudero, Fani-Fay Goltsios, Sahar Soodbakhsh, Hana Maalaoui, Éric Simard, Vladimir I. Titorenko

Published Sep 5, 2019

Keywords: cellular aging, geroprotectors, lipid metabolism, necrotic cell death, mitochondria

DS-1205b, a novel selective inhibitor of AXL kinase, blocks resistance to EGFR-tyrosine kinase inhibitors in a non-small cell lung cancer xenograft model Research Paper

Takeshi Jimbo, Mana Hatanaka, Takahiro Komatsu, Tomoe Taira, Kentaro Kumazawa, Naoyuki Maeda, Takashi Suzuki, Masahiro Ota, Noriyasu Haginoya, Takeshi Isoyama, Kosaku Fujiwara

Published Aug 27, 2019 · Vol. 10, No. 50 · pp. 5152-5167

Keywords: AXL, DS-1205, EGFR-TKI resistance, erlotinib, osimertinib

Role of the P2X7 receptor in in vitro and in vivo glioma tumor growth Research Paper

Letícia Scussel Bergamin, Marina Capece, Erica Salaro, Alba Clara Sarti, Simonetta Falzoni, Mery Stéfani Leivas Pereira, Marco Antônio De Bastiani, Juliete Nathali Scholl, Ana Maria O. Battastini, Francesco Di Virgilio

Published Aug 6, 2019 · Vol. 10, No. 47 · pp. 4840-4856

Keywords: cancer, glioma, P2X7R, purinergic signaling, extracellular ATP

Combinatorial drug screening of mammary cells with induced mesenchymal transformation to identify drug combinations for triple-negative breast cancer Research Paper

Sierra A. Colavito, James T. Platt, Matthew A. Held, Zongzhi Liu, Ryan Sokup, David F. Stern

Published Aug 6, 2019 · Vol. 10, No. 47 · pp. 4822-4839

Keywords: epithelial-mesenchymal transition, triple-negative breast cancer, targeted drug combination screen, claudin-low breast cancer, CHK1

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Aberrant epigenetic silencing of neuronatin is a frequent event in human osteosarcoma Research Paper

Expression of Nrf2 and NF-κB transcription factors in breast cancer and breast fibroadenoma: Insights for a new therapeutic approach Research Paper

Correction: Frankincense essential oil suppresses melanoma cancer through down regulation of Bcl-2/Bax cascade signaling and ameliorates heptotoxicity via phase I and II drug metabolizing enzymes Correction

The anti-tumor activity of pralatrexate (PDX) correlates with the expression of RFC and DHFR mRNA in preclinical models of multiple myeloma Research Paper

The anti-tumor activity of pralatrexate (PDX) correlates with the expression of RFC and DHFR mRNA in preclinical models of multiple myeloma Research Paper

The anti-tumor activity of pralatrexate (PDX) correlates with the expression of RFC and DHFR mRNA in preclinical models of multiple myeloma Research Paper

DNA dependent protein kinase (DNA-PK) enhances HIV transcription by promoting RNA polymerase II activity and recruitment of transcription machinery at HIV LTR Research Paper

The synergistic inhibitory effect of combining therapies targeting EGFR and mitochondria in sarcomas Research Paper

Reactive oxygen/nitrogen species contribute substantially to the antileukemia effect of APO866, a NAD lowering agent Research Paper

Dynamic transition of the blood-brain barrier in the development of non-small cell lung cancer brain metastases Research Paper

Effect of Fms-like tyrosine kinase 3 (FLT3) ligand (FL) on antitumor activity of gilteritinib, a FLT3 inhibitor, in mice xenografted with FL-overexpressing cells Research Paper

Targeting glutaminase1 and synergizing with clinical drugs achieved more promising antitumor activity on multiple myeloma Research Paper

Mechanisms by which PE21, an extract from the white willow Salix alba, delays chronological aging in budding yeast Research Paper

Correction: Metformin sensitizes anticancer effect of dasatinib in head and neck squamous cell carcinoma cells through AMPK-dependent ER stress Correction

Dual-Targeting AKT2 and ERK in cancer stem-like cells in neuroblastoma Research Paper

Dual-Targeting AKT2 and ERK in cancer stem-like cells in neuroblastoma Research Paper

Mechanisms by which PE21, an extract from the white willow Salix alba, delays chronological aging in budding yeast Research Paper

DS-1205b, a novel selective inhibitor of AXL kinase, blocks resistance to EGFR-tyrosine kinase inhibitors in a non-small cell lung cancer xenograft model Research Paper

Role of the P2X7 receptor in in vitro and in vivo glioma tumor growth Research Paper

Combinatorial drug screening of mammary cells with induced mesenchymal transformation to identify drug combinations for triple-negative breast cancer Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Aberrant epigenetic silencing of neuronatin is a frequent event in human osteosarcoma Research Paper

Expression of Nrf2 and NF-κB transcription factors in breast cancer and breast fibroadenoma: Insights for a new therapeutic approach Research Paper

Correction: Frankincense essential oil suppresses melanoma cancer through down regulation of Bcl-2/Bax cascade signaling and ameliorates heptotoxicity via phase I and II drug metabolizing enzymes Correction

The anti-tumor activity of pralatrexate (PDX) correlates with the expression of RFC and DHFR mRNA in preclinical models of multiple myeloma Research Paper

The anti-tumor activity of pralatrexate (PDX) correlates with the expression of RFC and DHFR mRNA in preclinical models of multiple myeloma Research Paper

The anti-tumor activity of pralatrexate (PDX) correlates with the expression of RFC and DHFR mRNA in preclinical models of multiple myeloma Research Paper

DNA dependent protein kinase (DNA-PK) enhances HIV transcription by promoting RNA polymerase II activity and recruitment of transcription machinery at HIV LTR Research Paper

The synergistic inhibitory effect of combining therapies targeting EGFR and mitochondria in sarcomas Research Paper

Reactive oxygen/nitrogen species contribute substantially to the antileukemia effect of APO866, a NAD lowering agent Research Paper

Dynamic transition of the blood-brain barrier in the development of non-small cell lung cancer brain metastases Research Paper

Effect of Fms-like tyrosine kinase 3 (FLT3) ligand (FL) on antitumor activity of gilteritinib, a FLT3 inhibitor, in mice xenografted with FL-overexpressing cells Research Paper

Targeting glutaminase1 and synergizing with clinical drugs achieved more promising antitumor activity on multiple myeloma Research Paper

Mechanisms by which PE21, an extract from the white willow Salix alba, delays chronological aging in budding yeast Research Paper

Correction: Metformin sensitizes anticancer effect of dasatinib in head and neck squamous cell carcinoma cells through AMPK-dependent ER stress Correction

Dual-Targeting AKT2 and ERK in cancer stem-like cells in neuroblastoma Research Paper

Dual-Targeting AKT2 and ERK in cancer stem-like cells in neuroblastoma Research Paper

Mechanisms by which PE21, an extract from the white willow Salix alba, delays chronological aging in budding yeast Research Paper

DS-1205b, a novel selective inhibitor of AXL kinase, blocks resistance to EGFR-tyrosine kinase inhibitors in a non-small cell lung cancer xenograft model Research Paper

Role of the P2X7 receptor in in vitro and in vivo glioma tumor growth Research Paper

Combinatorial drug screening of mammary cells with induced mesenchymal transformation to identify drug combinations for triple-negative breast cancer Research Paper