Oncotarget

Research Perspectives:

The goal of geroscience is life extension

Mikhail V. Blagosklonny _

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Oncotarget. 2021; 12:131-144. https://doi.org/10.18632/oncotarget.27882

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Abstract

Mikhail V. Blagosklonny1

1 Roswell Park Cancer Institute, Buffalo, NY 14263, USA

Correspondence to:

Mikhail V. Blagosklonny,email: Blagosklonny@oncotarget.com,
Blagosklonny@rapalogs.com

Keywords: aging; longevity; rapamycin; mTOR; metformin

Received: December 23, 2020     Accepted: January 13, 2021     Published: February 02, 2021

Copyright: © 2021 Blagosklonny. This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

ABSTRACT

Although numerous drugs seemingly extend healthspan in mice, only a few extend lifespan in mice and only one does it consistently. Some of them, alone or in combination, can be used in humans, without further clinical trials.


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PII: 27882