P-cadherin mutations are associated with high basal Wnt activity and stemness in canine mammary tumor cell lines
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Elpetra Timmermans-Sprang1, Rob Collin2,3, Arjen Henkes2, Meike Philipsen1 and Jan A. Mol1
1 Department of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands
2 Department of Human Genetics, Radboud University Medical Center, Nijmegen, The Netherlands
3 Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands
|Jan A. Mol,||email:||J.A.Mol@uu.nl|
Keywords: cancer stem cell; canine mammary tumor exome-sequencing; CDH3; Wnt; cSRC
Received: October 18, 2018 Accepted: April 04, 2019 Published: April 26, 2019
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