Oncotarget

Vol 9, No 71

September 11, 2018

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About The Cover

The cover for issue 71 of Oncotarget features Figure 1B, "Schematic representation to illustrate the differential binding and internalization of low affinity EGFR-ADC on normal cells versus tumor cells that express higher level of the receptors," by Wong, et al.

Table of Contents

Editorial

CXCR4 antagonists for treatment of breast cancer

CXCR4 antagonists for treatment of breast cancer

https://doi.org/10.18632/oncotarget.26090

Javier Cortés, Esther Holgado,  and Jose Perez-Garcia
33442-33443
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Boosting chemokine receptor recycling: an elixir of life for chronic lymphocytic leukemia

Boosting chemokine receptor recycling: an elixir of life for chronic lymphocytic leukemia

https://doi.org/10.18632/oncotarget.26099

Laura Patrussi,  and Cosima T. Baldari
33444-33445
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Priority Research Papers

RN765C, a low affinity EGFR antibody drug conjugate with potent anti-tumor activity in preclinical solid tumor models

RN765C, a low affinity EGFR antibody drug conjugate with potent anti-tumor activity in preclinical solid tumor models

https://doi.org/10.18632/oncotarget.26002

Oi Kwan Wong, Thomas-Toan Tran, Wei-Hsien Ho, Meritxell Galindo Casas, Melinda Au, Marjorie Bateman, Kevin C. Lindquist, Arvind Rajpal, David L. Shelton, Pavel Strop,  and Shu-Hui Liu
33446-33458
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Research Papers

TRPV2 is a novel biomarker and therapeutic target in triple negative breast cancer

TRPV2 is a novel biomarker and therapeutic target in triple negative breast cancer

https://doi.org/10.18632/oncotarget.9663

Mohamad Elbaz, Dinesh Ahirwar, Zhang Xiaoli, Xinyu Zhou, Maryam Lustberg, Mohd W. Nasser, Konstantin Shilo,  and Ramesh K. Ganju
33459-33470
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Silencing of the nucleocytoplasmic shuttling protein karyopherin a2 promotes cell-cycle arrest and apoptosis in glioblastoma multiforme

Silencing of the nucleocytoplasmic shuttling protein karyopherin a2 promotes cell-cycle arrest and apoptosis in glioblastoma multiforme

https://doi.org/10.18632/oncotarget.26033

Ramon Martinez-Olivera, Angeliki Datsi, Maren Stallkamp, Manfred Köller, Isabelle Kohtz, Bogdan Pintea,  and Konstantinos Gousias
33471-33481
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Generation and characteristics of a novel “double-hit” high grade B-cell lymphoma cell line DH-My6 with MYC/IGH and BCL6/IGH gene arrangements and potential molecular targeted therapies

Generation and characteristics of a novel “double-hit” high grade B-cell lymphoma cell line DH-My6 with MYC/IGH and BCL6/IGH gene arrangements and potential molecular targeted therapies

https://doi.org/10.18632/oncotarget.26060

Hiroaki Kikuchi, Tomonori Higuchi, Yumiko Hashida, Ayuko Taniguchi, Mikio Kamioka, Takahiro Taguchi, Akihito Yokoyama, Ichiro Murakami, Mikiya Fujieda,  and Masanori Daibata
33482-33499
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Comparative proteomic analysis of cat eye syndrome critical region protein 1- function in tumor-associated macrophages and immune response regulation of glial tumors

Comparative proteomic analysis of cat eye syndrome critical region protein 1- function in tumor-associated macrophages and immune response regulation of glial tumors

https://doi.org/10.18632/oncotarget.26063

Changbin Zhu, Dana A.M. Mustafa, Merle M. Krebber, Ihsan Chrifi, Pieter J.M. Leenen, Dirk J. Duncker, Lennard Dekker, Theo M. Luider, Johan M. Kros,  and Caroline Cheng
33500-33514
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SSeCKS/Akap12 suppresses metastatic melanoma lung colonization by attenuating Src-mediated pre-metastatic niche crosstalk

SSeCKS/Akap12 suppresses metastatic melanoma lung colonization by attenuating Src-mediated pre-metastatic niche crosstalk

https://doi.org/10.18632/oncotarget.26067

Masashi Muramatsu, Shin Akakura, Lingqiu Gao, Jennifer Peresie, Benjamin Balderman,  and Irwin H. Gelman
33515-33527
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Clofarabine-based reduced intensity conditioning regimen with peripheral blood stem cell graft and post-transplant cyclophosphamide in adults with myeloid malignancies

Clofarabine-based reduced intensity conditioning regimen with peripheral blood stem cell graft and post-transplant cyclophosphamide in adults with myeloid malignancies

https://doi.org/10.18632/oncotarget.26083

Patrice Chevallier, Pierre Peterlin, Alice Garnier, Amandine Le Bourgeois, Beatrice Mahé, Viviane Dubruille, Nicolas Blin, Cyrille Touzeau, Thomas Gastinne, Anne Lok, Yannick Le Bris, Marie C. Béné, Steven Le Gouill, Philippe Moreau,  and Thierry Guillaume
33528-33535
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Intestinal epithelial Notch-1 protects from colorectal mucinous adenocarcinoma

Intestinal epithelial Notch-1 protects from colorectal mucinous adenocarcinoma

https://doi.org/10.18632/oncotarget.26086

David Dunkin, Alina C. Iuga, Sanda Mimouna, Carolyn L. Harris, Jean-Vianney Haure-Mirande, Dominique Bozec, Garabet Yeretssian,  and Stephanie Dahan
33536-33548
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The Akt/mTOR pathway in cancer stem/progenitor cells is a potential therapeutic target for glioblastoma and neuroblastoma

The Akt/mTOR pathway in cancer stem/progenitor cells is a potential therapeutic target for glioblastoma and neuroblastoma

https://doi.org/10.18632/oncotarget.26088

Hisham F. Bahmad, Tarek H. Mouhieddine, Reda M. Chalhoub, Sahar Assi, Tarek Araji, Farah Chamaa, Muhieddine M. Itani, Amaly Nokkari, Firas Kobeissy, Georges Daoud,  and Wassim Abou-Kheir
33549-33561
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Elucidating the novel BRCA1 function as a non-genomic metabolic restraint in ER-positive breast cancer cell lines

Elucidating the novel BRCA1 function as a non-genomic metabolic restraint in ER-positive breast cancer cell lines

https://doi.org/10.18632/oncotarget.26093

Moses Koobotse, Jeff Holly,  and Claire Perks
33562-33576
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MiR-29b-1-5p is altered in BRCA1 mutant tumours and is a biomarker in basal-like breast cancer

MiR-29b-1-5p is altered in BRCA1 mutant tumours and is a biomarker in basal-like breast cancer

https://doi.org/10.18632/oncotarget.26094

Michael J.G. Milevskiy, Gurveen K. Sandhu, Anna Wronski, Darren Korbie, Brooke L. Brewster, Annette Shewan, Stacey L. Edwards, Juliet D. French,  and Melissa A. Brown
33577-33588
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Adaptation to chronic exposure to sepantronium bromide (YM155), a prototypical survivin suppressant is due to persistent DNA damage-response in breast cancer cells

Adaptation to chronic exposure to sepantronium bromide (YM155), a prototypical survivin suppressant is due to persistent DNA damage-response in breast cancer cells

https://doi.org/10.18632/oncotarget.26096

Tasaduq H. Wani, Sreeraj Surendran, Vishnu S. Mishra, Jaya Chaturvedi, Goutam Chowdhury,  and Anindita Chakrabarty
33589-33600
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Reviews

Active ginseng components in cognitive impairment: Therapeutic potential and prospects for delivery and clinical study

Active ginseng components in cognitive impairment: Therapeutic potential and prospects for delivery and clinical study

https://doi.org/10.18632/oncotarget.26035

Md. Jakaria, Md. Ezazul Haque, Joonsoo Kim, Duk-Yeon Cho, In-Su Kim,  and Dong-Kug Choi
33601-33620
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