The Oncosearch | Oncotarget

The BH3-mimetic gossypol and noncytotoxic doses of valproic acid induce apoptosis by suppressing cyclin-A2/Akt/FOXO3a signaling Research Paper

Gao-Xiang Zhao, Li-Hui Xu, Hao Pan, Qiu-Ru Lin, Mei-Yun Huang, Ji-Ye Cai, Dong-Yun Ouyang, Xian-Hui He

Published Oct 16, 2015 · Vol. 6, No. 36 · pp. 38952-38966

SMAC mimetic Debio 1143 synergizes with taxanes, topoisomerase inhibitors and bromodomain inhibitors to impede growth of lung adenocarcinoma cells Research Paper

Casey G. Langdon, Norbert Wiedemann, Matthew A. Held, Ramanaiah Mamillapalli, Pinar Iyidogan, Nicholas Theodosakis, James T. Platt, Frederic Levy, Gregoire Vuagniaux, Shaomeng Wang, Marcus W. Bosenberg, David F. Stern

Published Oct 16, 2015 · Vol. 6, No. 35 · pp. 37410-37425

Targeting mitochondrial RNA polymerase in acute myeloid leukemia Research Paper

Fernando N. Bralha, Sanduni U. Liyanage, Rose Hurren, Xiaoming Wang, Meong Hi Son, Thomas A. Fung, Francine B. Chingcuanco, Aveline Y. W. Tung, Ana C. Andreazza, Pamela Psarianos, Aaron D. Schimmer, Leonardo Salmena, Rebecca R. Laposa

Published Oct 15, 2015 · Vol. 6, No. 35 · pp. 37216-37228

Honokiol inhibits bladder tumor growth by suppressing EZH2/miR-143 axis Research Paper

Qing Zhang, Wei Zhao, Changxiao Ye, Junlong Zhuang, Cunjie Chang, Yuying Li, Xiaojing Huang, Lan Shen, Yan Li, Yangyan Cui, Jiannan Song, Bing Shen, Isaac Eliaz, Ruimin Huang, Hao Ying, Hongqian Guo, Jun Yan

Published Oct 15, 2015 · Vol. 6, No. 35 · pp. 37335-37348

MiR-744 increases tumorigenicity of pancreatic cancer by activating Wnt/Î²-catenin pathway Research Paper

Wei Zhou, Yongfeng Li, Shanmiao Gou, Jiongxin Xiong, Heshui Wu, Chunyou Wang, Haijiao Yan, Tao Liu

Published Oct 15, 2015 · Vol. 6, No. 35 · pp. 37557-37569

IGF-1R inhibition induces schedule-dependent sensitization of human melanoma to temozolomide Research Paper

Roger Ramcharan, Tamara Aleksic, Wilfride Petnga Kamdoum, Shan Gao, Sophia X. Pfister, Jordan Tanner, Esther Bridges, Ruth Asher, Amanda J. Watson, Geoffrey P. Margison, Mick Woodcock, Emmanouela Repapi, Ji-Liang Li, Mark R. Middleton, Valentine M. Macaulay

Published Oct 15, 2015 · Vol. 6, No. 37 · pp. 39877-39890

LncRNA MALAT1 enhances oncogenic activities of EZH2 in castration-resistant prostate cancer Research Paper

Dejie Wang, Liya Ding, Liguo Wang, Yu Zhao, Zhifu Sun, R.Jeffrey Karnes, Jun Zhang, Haojie Huang

Published Oct 15, 2015 · Vol. 6, No. 38 · pp. 41045-41055

Involvement of Wnt/β-catenin signaling in the mesenchymal stem cells promote metastatic growth and chemoresistance of cholangiocarcinoma Research Paper

Weiwei Wang, Wei Zhong, Jiahui Yuan, Congcong Yan, Shaoping Hu, Yinping Tong, Yubin Mao, Tianhui Hu, Bing Zhang, Gang Song

Published Oct 14, 2015 · Vol. 6, No. 39 · pp. 42276-42289

The potent tumor suppressor miR-497 inhibits cancer phenotypes in nasopharyngeal carcinoma by targeting ANLN and HSPA4L Research Paper

Shumin Wang, Yingxi Mo, Kaoru Midorikawa, Zhe Zhang, Guangwu Huang, Ning Ma, Weilin Zhao, Yusuke Hiraku, Shinji Oikawa, Mariko Murata

Published Oct 14, 2015 · Vol. 6, No. 34 · pp. 35893-35907

Overexpression of Mcl-1 confers resistance to BRAF^V600E inhibitors alone and in combination with MEK1/2 inhibitors in melanoma Research Paper

Neel M. Fofaria, Dennie T. Frederick, Ryan J. Sullivan, Keith T. Flaherty, Sanjay K. Srivastava

Published Oct 14, 2015 · Vol. 6, No. 38 · pp. 40535-40556

Arsenic trioxide disrupts glioma stem cells via promoting PML degradation to inhibit tumor growth Research Paper

Wenchao Zhou, Lin Cheng, Yu Shi, Susan Q. Ke, Zhi Huang, Xiaoguang Fang, Cheng-wei Chu, Qi Xie, Xiu-wu Bian, Jeremy N. Rich, Shideng Bao

Published Oct 14, 2015 · Vol. 6, No. 35 · pp. 37300-37315

Doxycycline reverses epithelial-to-mesenchymal transition and suppresses the proliferation and metastasis of lung cancer cells Research Paper

Yuan Qin, Qiang Zhang, Shan Lee, Wei-long Zhong, Yan-rong Liu, Hui-juan Liu, Dong Zhao, Shuang Chen, Ting Xiao, Jing Meng, Xue-shuang Jing, Jing Wang, Bo Sun, Ting-ting Dai, Cheng Yang, Tao Sun, Hong-gang Zhou

Published Oct 14, 2015 · Vol. 6, No. 38 · pp. 40667-40679

Targeting EMP3 suppresses proliferation and invasion of hepatocellular carcinoma cells through inactivation of PI3K/Akt pathway Research Paper

Yi-Hsien Hsieh, Shu-Ching Hsieh, Chien-Hsing Lee, Shun-Fa Yang, Chun-Wen Cheng, Meng-Ju Tang, Chia-Liang Lin, Chu-Liang Lin, Ruey-Hwang Chou

Published Oct 12, 2015 · Vol. 6, No. 33 · pp. 34859-34874

MDA-7/IL-24 functions as a tumor suppressor gene in vivo in transgenic mouse models of breast cancer Priority Research Paper

Mitchell E. Menezes, Xue-Ning Shen, Swadesh K. Das, Luni Emdad, Chunqing Guo, Fang Yuan, You-Jun Li, Michael C. Archer, Eldad Zacksenhaus, Jolene J. Windle, Mark A. Subler, Yaacov Ben-David, Devanand Sarkar, Xiang-Yang Wang, Paul B. Fisher

Published Oct 12, 2015 · Vol. 6, No. 35 · pp. 36928-36942

Tunicamycin enhances the antitumor activity of trastuzumab on breast cancer in vitro and in vivo Research Paper

Xiqian Han, Xiaobing Zhang, Hui Li, Shengshi Huang, Shu Zhang, Fengshan Wang, Yikang Shi

Published Oct 12, 2015 · Vol. 6, No. 36 · pp. 38912-38925

Inhibition of endoplasmic reticulum chaperone protein glucose-regulated protein 78 potentiates anti-angiogenic therapy in renal cell carcinoma through inactivation of the PERK/eIF2α pathway Research Paper

Kyung Seok Han, Na Li, Pater A. Raven, Ladan Fazli, Sebastian Frees, Susan Ettinger, Ki Chung Park, Sung Joon Hong, Martin E. Gleave, Alan I. So

Published Oct 12, 2015 · Vol. 6, No. 33 · pp. 34818-34830

Targeting Syndecan-1, a molecule implicated in the process of vasculogenic mimicry, enhances the therapeutic efficacy of the L19-IL2 immunocytokine in human melanoma xenografts Research Paper

Paola Orecchia, Romana Conte, Enrica Balza, Gabriella Pietra, Maria Cristina Mingari, Barbara Carnemolla

Published Oct 9, 2015 · Vol. 6, No. 35 · pp. 37426-37442

Rescuing lymphocytes from HLA-G immunosuppressive effects mediated by the tumor microenvironment Research Paper

Danli Wu, Isere Kuiaste, Philippe Moreau, Edgardo Carosella, Patricia Yotnda

Published Oct 9, 2015 · Vol. 6, No. 35 · pp. 37385-37397

Effects of a novel Nodal-targeting monoclonal antibody in melanoma Priority Research Paper

Luigi Strizzi, Annamaria Sandomenico, Naira V. Margaryan, Annalia FocÃ, Luca Sanguigno, Thomas M. Bodenstine, Grace S. Chandler, David W. Reed, Alina Gilgur, Elisabeth A. Seftor, Richard E.B. Seftor, Zhila Khalkhali-Ellis, Antonio Leonardi, Menotti Ruvo, Mary J.C. Hendrix

Published Oct 9, 2015 · Vol. 6, No. 33 · pp. 34071-34086

Combinatorial TGF-Î² attenuation with paclitaxel inhibits the epithelial-to-mesenchymal transition and breast cancer stem-like cells Research Paper

So-Yeon Park, Min-Jin Kim, Sang-A Park, Jung-Shin Kim, Kyung-Nan Min, Dae-Kee Kim, Woosung Lim, Jeong-Seok Nam, Yhun Yhong Sheen

Published Oct 9, 2015 · Vol. 6, No. 35 · pp. 37526-37543

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The BH3-mimetic gossypol and noncytotoxic doses of valproic acid induce apoptosis by suppressing cyclin-A2/Akt/FOXO3a signaling Research Paper

SMAC mimetic Debio 1143 synergizes with taxanes, topoisomerase inhibitors and bromodomain inhibitors to impede growth of lung adenocarcinoma cells Research Paper

Targeting mitochondrial RNA polymerase in acute myeloid leukemia Research Paper

Honokiol inhibits bladder tumor growth by suppressing EZH2/miR-143 axis Research Paper

MiR-744 increases tumorigenicity of pancreatic cancer by activating Wnt/Î²-catenin pathway Research Paper

IGF-1R inhibition induces schedule-dependent sensitization of human melanoma to temozolomide Research Paper

LncRNA MALAT1 enhances oncogenic activities of EZH2 in castration-resistant prostate cancer Research Paper

Involvement of Wnt/β-catenin signaling in the mesenchymal stem cells promote metastatic growth and chemoresistance of cholangiocarcinoma Research Paper

The potent tumor suppressor miR-497 inhibits cancer phenotypes in nasopharyngeal carcinoma by targeting ANLN and HSPA4L Research Paper

Overexpression of Mcl-1 confers resistance to BRAF^V600E inhibitors alone and in combination with MEK1/2 inhibitors in melanoma Research Paper

Arsenic trioxide disrupts glioma stem cells via promoting PML degradation to inhibit tumor growth Research Paper

Doxycycline reverses epithelial-to-mesenchymal transition and suppresses the proliferation and metastasis of lung cancer cells Research Paper

Targeting EMP3 suppresses proliferation and invasion of hepatocellular carcinoma cells through inactivation of PI3K/Akt pathway Research Paper

MDA-7/IL-24 functions as a tumor suppressor gene in vivo in transgenic mouse models of breast cancer Priority Research Paper

Tunicamycin enhances the antitumor activity of trastuzumab on breast cancer in vitro and in vivo Research Paper

Inhibition of endoplasmic reticulum chaperone protein glucose-regulated protein 78 potentiates anti-angiogenic therapy in renal cell carcinoma through inactivation of the PERK/eIF2α pathway Research Paper

Targeting Syndecan-1, a molecule implicated in the process of vasculogenic mimicry, enhances the therapeutic efficacy of the L19-IL2 immunocytokine in human melanoma xenografts Research Paper

Rescuing lymphocytes from HLA-G immunosuppressive effects mediated by the tumor microenvironment Research Paper

Effects of a novel Nodal-targeting monoclonal antibody in melanoma Priority Research Paper

Combinatorial TGF-Î² attenuation with paclitaxel inhibits the epithelial-to-mesenchymal transition and breast cancer stem-like cells Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

The BH3-mimetic gossypol and noncytotoxic doses of valproic acid induce apoptosis by suppressing cyclin-A2/Akt/FOXO3a signaling Research Paper

SMAC mimetic Debio 1143 synergizes with taxanes, topoisomerase inhibitors and bromodomain inhibitors to impede growth of lung adenocarcinoma cells Research Paper

Targeting mitochondrial RNA polymerase in acute myeloid leukemia Research Paper

Honokiol inhibits bladder tumor growth by suppressing EZH2/miR-143 axis Research Paper

MiR-744 increases tumorigenicity of pancreatic cancer by activating Wnt/Î²-catenin pathway Research Paper

IGF-1R inhibition induces schedule-dependent sensitization of human melanoma to temozolomide Research Paper

LncRNA MALAT1 enhances oncogenic activities of EZH2 in castration-resistant prostate cancer Research Paper

Involvement of Wnt/β-catenin signaling in the mesenchymal stem cells promote metastatic growth and chemoresistance of cholangiocarcinoma Research Paper

The potent tumor suppressor miR-497 inhibits cancer phenotypes in nasopharyngeal carcinoma by targeting ANLN and HSPA4L Research Paper

Overexpression of Mcl-1 confers resistance to BRAFV600E inhibitors alone and in combination with MEK1/2 inhibitors in melanoma Research Paper

Arsenic trioxide disrupts glioma stem cells via promoting PML degradation to inhibit tumor growth Research Paper

Doxycycline reverses epithelial-to-mesenchymal transition and suppresses the proliferation and metastasis of lung cancer cells Research Paper

Targeting EMP3 suppresses proliferation and invasion of hepatocellular carcinoma cells through inactivation of PI3K/Akt pathway Research Paper

MDA-7/IL-24 functions as a tumor suppressor gene in vivo in transgenic mouse models of breast cancer Priority Research Paper

Tunicamycin enhances the antitumor activity of trastuzumab on breast cancer in vitro and in vivo Research Paper

Inhibition of endoplasmic reticulum chaperone protein glucose-regulated protein 78 potentiates anti-angiogenic therapy in renal cell carcinoma through inactivation of the PERK/eIF2α pathway Research Paper

Targeting Syndecan-1, a molecule implicated in the process of vasculogenic mimicry, enhances the therapeutic efficacy of the L19-IL2 immunocytokine in human melanoma xenografts Research Paper

Rescuing lymphocytes from HLA-G immunosuppressive effects mediated by the tumor microenvironment Research Paper

Effects of a novel Nodal-targeting monoclonal antibody in melanoma Priority Research Paper

Combinatorial TGF-Î² attenuation with paclitaxel inhibits the epithelial-to-mesenchymal transition and breast cancer stem-like cells Research Paper

Overexpression of Mcl-1 confers resistance to BRAF^V600E inhibitors alone and in combination with MEK1/2 inhibitors in melanoma Research Paper