The Oncosearch | Oncotarget

Vemurafenib-resistant BRAF-V600E-mutated melanoma is regressed by MEK-targeting drug trametinib, but not cobimetinib in a patient-derived orthotopic xenograft (PDOX) mouse model Research Paper

Kei Kawaguchi, Takashi Murakami, Bartosz Chmielowski, Kentaro Igarashi, Tasuku Kiyuna, Michiaki Unno, Scott D. Nelson, Tara A. Russell, Sarah M. Dry, Yunfeng Li, Fritz C. Eilber, Robert M. Hoffman

Published Sep 28, 2016 · Vol. 7, No. 44 · pp. 71737-71743

Patient-derived mouse models of cancer need to be orthotopic in order to evaluate targeted anti-metastatic therapy Research Paper

Yukihiko Hiroshima, Ali Maawy, Yong Zhang, Nan Zhang, Takashi Murakami, Takashi Chishima, Kuniya Tanaka, Yasushi Ichikawa, Michael Bouvet, Itaru Endo, Robert M. Hoffman

Published Sep 28, 2016 · Vol. 7, No. 44 · pp. 71696-71702

The natural compound sulforaphene, as a novel anticancer reagent, targeting PI3K-AKT signaling pathway in lung cancer Research Paper

Ming Yang, Haiyong Wang, Mo Zhou, Weilin Liu, Pengqun Kuang, Hao Liang, Qipeng Yuan

Published Sep 28, 2016 · Vol. 7, No. 47 · pp. 76656-76666

CARP-1 functional mimetics are novel inhibitors of drug-resistant triple negative breast cancers Research Paper

Vino T. Cheriyan, Magesh Muthu, Ketan Patel, Sreeja Sekhar, Walajapet Rajeswaran, Scott D. Larsen, Lisa Polin, Edi Levi, Mandip Singh, Arun K. Rishi

Published Sep 28, 2016 · Vol. 7, No. 45 · pp. 73370-73388

IL-10 secreted by M2 macrophage promoted tumorigenesis through interaction with JAK2 in glioma Research Paper

Ling Qi, Hongquan Yu, Yu Zhang, Donghai Zhao, Peng Lv, Yue Zhong, Ye Xu

Published Sep 28, 2016 · Vol. 7, No. 44 · pp. 71673-71685

Resistance to PARP inhibitors by SLFN11 inactivation can be overcome by ATR inhibition Research Paper

Junko Murai, Ying Feng, Guoying K. Yu, Yuanbin Ru, Sai-Wen Tang, Yuqiao Shen, Yves Pommier

Published Sep 27, 2016 · Vol. 7, No. 47 · pp. 76534-76550

PARP1 inhibitor olaparib (Lynparza) exerts synthetic lethal effect against ligase 4-deficient melanomas Research Paper

MaÅ‚gorzata CzyÅ¼, Monika Toma, Anna Gajos-Michniewicz, Kinga Majchrzak, Grazyna Hoser, Janusz Szemraj, Margaret Nieborowska-Skorska, Phil Cheng, Daniel Gritsyuk, Mitchell Levesque, Reinhard Dummer, Tomasz Sliwinski, Tomasz Skorski

Published Sep 27, 2016 · Vol. 7, No. 46 · pp. 75551-75560

Intratumoral radiofrequency hyperthermia-enhanced direct chemotherapy of pancreatic cancer Clinical Research Papers

Zhibin Bai, Yaoping Shi, Jianfeng Wang, Longhua Qiu, Eric J. Monroe, Gaojun Teng, Feng Zhang, Xiaoming Yang

Published Sep 27, 2016 · Vol. 8, No. 2 · pp. 3591-3599

Long noncoding RNA uc.345 promotes tumorigenesis of pancreatic cancer by upregulation of hnRNPL expression Research Paper

Chao Liu, Jiamin Wang, Xiaoyuan Yuan, Wenli Qian, Bosen Zhang, Minmin Shi, Junjie Xie, Baiyong Shen, Hong Xu, Zhaoyuan Hou, Hao Chen

Published Sep 26, 2016 · Vol. 7, No. 44 · pp. 71556-71566

In vivo phage display screening for tumor vascular targets in glioblastoma identifies a llama nanobody against dynactin-1-p150^Glued Research Paper

Sanne A.M. van Lith, Ilse Roodink, Joost J.C. Verhoeff, Petri I. MÃ¤kinen, Jari P. Lappalainen, Seppo YlÃ¤-Herttuala, Jos Raats, Erwin van Wijk, Ronald Roepman, Stef J. Letteboer, Kiek Verrijp, William P.J. Leenders

Published Sep 26, 2016 · Vol. 7, No. 44 · pp. 71594-71607

Polarization of macrophages in the tumor microenvironment is influenced by EGFR signaling within colon cancer cells Research Paper

Weina Zhang, Lechuang Chen, Kai Ma, Yahui Zhao, Xianghe Liu, Yu Wang, Mei Liu, Shufang Liang, Hongxia Zhu, Ningzhi Xu

Published Sep 23, 2016 · Vol. 7, No. 46 · pp. 75366-75378

Targeting endogenous DLK1 exerts antitumor effect on hepatocellular carcinoma through initiating cell differentiation Research Paper

Chun-Miao Cai, Xu Xiao, Bing-Hao Wu, Bao-Feng Wei, Ze-Guang Han

Published Sep 23, 2016 · Vol. 7, No. 44 · pp. 71466-71476

Silencing of Profilin-1 suppresses cell adhesion and tumor growth via predicted alterations in integrin and Ca²⁺ signaling in T24M-based bladder cancer models Research Paper

Maria Frantzi, Zoi Klimou, Manousos Makridakis, Jerome Zoidakis, Agnieszka Latosinska, Daniel M. BorrÃ s, Bart Janssen, Ioanna Giannopoulou, Vasiliki Lygirou, Andreas C. Lazaris, Nicholas P. Anagnou, Harald Mischak, Maria G. Roubelakis, Antonia Vlahou

Published Sep 23, 2016 · Vol. 7, No. 43 · pp. 70750-70768

FGF4 induces epithelial-mesenchymal transition by inducing store-operated calcium entry in lung adenocarcinoma Research Paper

Lisha Qi, Wangzhao Song, Lingmei Li, Lu Cao, Yue Yu, Chunmin Song, Yalei Wang, Fei Zhang, Yang Li, Bin Zhang, Wenfeng Cao

Published Sep 22, 2016 · Vol. 7, No. 45 · pp. 74015-74030

Impact of HuR inhibition by the small molecule MS-444 on colorectal cancer cell tumorigenesis Research Paper

Fernando F. Blanco, Ranjan Preet, Andrea Aguado, Vikalp Vishwakarma, Laura E. Stevens, Alok Vyas, Subhash Padhye, Liang Xu, Scott J. Weir, Shrikant Anant, Nicole Meisner-Kober, Jonathan R. Brody, Dan A. Dixon

Published Sep 22, 2016 · Vol. 7, No. 45 · pp. 74043-74058

Interferon-stimulated gene 15 induces cancer cell death by suppressing the NF-ÎºB signaling pathway Research Paper

Hongwu Mao, Man Wang, Biyin Cao, Haibin Zhou, Zubin Zhang, Xinliang Mao

Published Sep 21, 2016 · Vol. 7, No. 43 · pp. 70143-70151

Acetylation of androgen receptor by ARD1 promotes dissociation from HSP90 complex and prostate tumorigenesis Research Paper

John S. DePaolo, Zehua Wang, Jianhui Guo, Guanyi Zhang, Chiping Qian, Haitao Zhang, Jovanny Zabaleta, Wanguo Liu

Published Sep 21, 2016 · Vol. 7, No. 44 · pp. 71417-71428

MicroRNA-552 enhances metastatic capacity of colorectal cancer cells by targeting a disintegrin and metalloprotease 28 Research Paper

Jian Wang, Hai Li, Yong Wang, Libin Wang, Xiurui Yan, Dong Zhang, Xiaoqiang Ma, Yong Du, Xiaoming Liu, Yinxue Yang

Published Sep 21, 2016 · Vol. 7, No. 43 · pp. 70194-70210

MDM2 is a potential therapeutic target and prognostic factor for ovarian clear cell carcinomas with wild type TP53 Research Paper

Chinami Makii, Katsutoshi Oda, Yuji Ikeda, Kenbun Sone, Kosei Hasegawa, Yuriko Uehara, Akira Nishijima, Kayo Asada, Takahiro Koso, Tomohiko Fukuda, Kanako Inaba, Shinya Oki, Hidenori Machino, Machiko Kojima, Tomoko Kashiyama, Mayuyo Mori-Uchino, Takahide Arimoto, Osamu Wada-Hiraike, Kei Kawana, Tetsu Yano, Keiichi Fujiwara, Hiroyuki Aburatani, Yutaka Osuga, Tomoyuki Fujii

Published Sep 21, 2016 · Vol. 7, No. 46 · pp. 75328-75338

Nodal signaling promotes vasculogenic mimicry formation in breast cancer via the Smad2/3 pathway Research Paper

Wenchen Gong, Baocun Sun, Xiulan Zhao, Danfang Zhang, Junying Sun, Tieju Liu, Qiang Gu, Xueyi Dong, Fang Liu, Yong Wang, Xian Lin, Yanlei Li

Published Sep 21, 2016 · Vol. 7, No. 43 · pp. 70152-70167

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Vemurafenib-resistant BRAF-V600E-mutated melanoma is regressed by MEK-targeting drug trametinib, but not cobimetinib in a patient-derived orthotopic xenograft (PDOX) mouse model Research Paper

Patient-derived mouse models of cancer need to be orthotopic in order to evaluate targeted anti-metastatic therapy Research Paper

The natural compound sulforaphene, as a novel anticancer reagent, targeting PI3K-AKT signaling pathway in lung cancer Research Paper

CARP-1 functional mimetics are novel inhibitors of drug-resistant triple negative breast cancers Research Paper

IL-10 secreted by M2 macrophage promoted tumorigenesis through interaction with JAK2 in glioma Research Paper

Resistance to PARP inhibitors by SLFN11 inactivation can be overcome by ATR inhibition Research Paper

PARP1 inhibitor olaparib (Lynparza) exerts synthetic lethal effect against ligase 4-deficient melanomas Research Paper

Intratumoral radiofrequency hyperthermia-enhanced direct chemotherapy of pancreatic cancer Clinical Research Papers

Long noncoding RNA uc.345 promotes tumorigenesis of pancreatic cancer by upregulation of hnRNPL expression Research Paper

In vivo phage display screening for tumor vascular targets in glioblastoma identifies a llama nanobody against dynactin-1-p150^Glued Research Paper

Polarization of macrophages in the tumor microenvironment is influenced by EGFR signaling within colon cancer cells Research Paper

Targeting endogenous DLK1 exerts antitumor effect on hepatocellular carcinoma through initiating cell differentiation Research Paper

Silencing of Profilin-1 suppresses cell adhesion and tumor growth via predicted alterations in integrin and Ca²⁺ signaling in T24M-based bladder cancer models Research Paper

FGF4 induces epithelial-mesenchymal transition by inducing store-operated calcium entry in lung adenocarcinoma Research Paper

Impact of HuR inhibition by the small molecule MS-444 on colorectal cancer cell tumorigenesis Research Paper

Interferon-stimulated gene 15 induces cancer cell death by suppressing the NF-ÎºB signaling pathway Research Paper

Acetylation of androgen receptor by ARD1 promotes dissociation from HSP90 complex and prostate tumorigenesis Research Paper

MicroRNA-552 enhances metastatic capacity of colorectal cancer cells by targeting a disintegrin and metalloprotease 28 Research Paper

MDM2 is a potential therapeutic target and prognostic factor for ovarian clear cell carcinomas with wild type TP53 Research Paper

Nodal signaling promotes vasculogenic mimicry formation in breast cancer via the Smad2/3 pathway Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Vemurafenib-resistant BRAF-V600E-mutated melanoma is regressed by MEK-targeting drug trametinib, but not cobimetinib in a patient-derived orthotopic xenograft (PDOX) mouse model Research Paper

Patient-derived mouse models of cancer need to be orthotopic in order to evaluate targeted anti-metastatic therapy Research Paper

The natural compound sulforaphene, as a novel anticancer reagent, targeting PI3K-AKT signaling pathway in lung cancer Research Paper

CARP-1 functional mimetics are novel inhibitors of drug-resistant triple negative breast cancers Research Paper

IL-10 secreted by M2 macrophage promoted tumorigenesis through interaction with JAK2 in glioma Research Paper

Resistance to PARP inhibitors by SLFN11 inactivation can be overcome by ATR inhibition Research Paper

PARP1 inhibitor olaparib (Lynparza) exerts synthetic lethal effect against ligase 4-deficient melanomas Research Paper

Intratumoral radiofrequency hyperthermia-enhanced direct chemotherapy of pancreatic cancer Clinical Research Papers

Long noncoding RNA uc.345 promotes tumorigenesis of pancreatic cancer by upregulation of hnRNPL expression Research Paper

In vivo phage display screening for tumor vascular targets in glioblastoma identifies a llama nanobody against dynactin-1-p150Glued Research Paper

Polarization of macrophages in the tumor microenvironment is influenced by EGFR signaling within colon cancer cells Research Paper

Targeting endogenous DLK1 exerts antitumor effect on hepatocellular carcinoma through initiating cell differentiation Research Paper

Silencing of Profilin-1 suppresses cell adhesion and tumor growth via predicted alterations in integrin and Ca2+ signaling in T24M-based bladder cancer models Research Paper

FGF4 induces epithelial-mesenchymal transition by inducing store-operated calcium entry in lung adenocarcinoma Research Paper

Impact of HuR inhibition by the small molecule MS-444 on colorectal cancer cell tumorigenesis Research Paper

Interferon-stimulated gene 15 induces cancer cell death by suppressing the NF-ÎºB signaling pathway Research Paper

Acetylation of androgen receptor by ARD1 promotes dissociation from HSP90 complex and prostate tumorigenesis Research Paper

MicroRNA-552 enhances metastatic capacity of colorectal cancer cells by targeting a disintegrin and metalloprotease 28 Research Paper

MDM2 is a potential therapeutic target and prognostic factor for ovarian clear cell carcinomas with wild type TP53 Research Paper

Nodal signaling promotes vasculogenic mimicry formation in breast cancer via the Smad2/3 pathway Research Paper

In vivo phage display screening for tumor vascular targets in glioblastoma identifies a llama nanobody against dynactin-1-p150^Glued Research Paper

Silencing of Profilin-1 suppresses cell adhesion and tumor growth via predicted alterations in integrin and Ca²⁺ signaling in T24M-based bladder cancer models Research Paper