The Oncosearch | Oncotarget

Targeting the cancer stem cell marker, aldehyde dehydrogenase 1, to circumvent cisplatin resistance in NSCLC Research Paper

Lauren MacDonagh, Michael F. Gallagher, Brendan Ffrench, Claudia Gasch, Eamon Breen, Steven G. Gray, Siobhan Nicholson, Niamh Leonard, Ronan Ryan, Vincent Young, John J. Oâ€™Leary, Sinead Cuffe, Stephen P. Finn, Kenneth J. Oâ€™Byrne, Martin P. Barr

Published Aug 3, 2017 · Vol. 8, No. 42 · pp. 72544-72563

The histone methyltransferase EZH2 as a druggable target in SHH medulloblastoma cancer stem cells Research Paper

Evelina Miele, Sergio Valente, Vincenzo Alfano, Marianna Silvano, Paolo Mellini, Diana Borovika, Biagina Marrocco, Agnese Po, Zein Mersini Besharat, Giuseppina Catanzaro, Giuseppe Battaglia, Luana Abballe, Clemens Zwergel, Giulia Stazi, Ciro Milite, Sabrina Castellano, Marco Tafani, Peteris Trapencieris, Antonello Mai, Elisabetta Ferretti

Published Aug 2, 2017 · Vol. 8, No. 40 · pp. 68557-68570

Effect of weekly or daily dosing regimen of Gefitinib in mouse models of lung cancer Research Paper

Qi Zhang, Ruichao Li, Xu Chen, Sang Beom Lee, Jing Pan, Donghai Xiong, Jiaqi Hu, Mark Steven Miller, Eva Szabo, Ronald A. Lubet, Yian Wang, Ming You

Published Aug 2, 2017 · Vol. 8, No. 42 · pp. 72447-72456

IL-33 blockade suppresses tumor growth of human lung cancer through direct and indirect pathways in a preclinical model Research Paper

Kailing Wang, Shan Shan, Zongjun Yang, Xia Gu, Yuanyuan Wang, Chunhong Wang, Tao Ren

Published Aug 2, 2017 · Vol. 8, No. 40 · pp. 68571-68582

Antitumor efficacy of triple monoclonal antibody inhibition of epidermal growth factor receptor (EGFR) with MM151 in EGFR-dependent and in cetuximab-resistant human colorectal cancer cells Research Paper

Stefania Napolitano, Giulia Martini, Erika Martinelli, Carminia Maria Della Corte, Floriana Morgillo, Valentina Belli, Claudia Cardone, Nunzia Matrone, Fortunato Ciardiello, Teresa Troiani

Published Aug 2, 2017 · Vol. 8, No. 47 · pp. 82773-82783

Targeting the PI3K/AKT/mTOR signaling pathway as an effectively radiosensitizing strategy for treating human oral squamous cell carcinoma in vitro and in vivo Research Paper

Chih-Chia Yu, Shih-Kai Hung, Hon-Yi Lin, Wen-Yen Chiou, Moon-Sing Lee, Hui-Fen Liao, Hsien-Bin Huang, Hsu-Chueh Ho, Yu-Chieh Su

Published Aug 2, 2017 · Vol. 8, No. 40 · pp. 68641-68653

Positive transcription elongation factor b (P-TEFb) is a therapeutic target in human multiple myeloma Research Paper

Yu Zhang, Liang Zhou, Yun Leng, Yun Dai, Robert Z. Orlowski, Steven Grant

Published Aug 1, 2017 · Vol. 8, No. 35 · pp. 59476-59491

Phenformin enhances the therapeutic effect of selumetinib in KRAS-mutant non-small cell lung cancer irrespective of LKB1 status Research Paper

Jun Zhang, Sreenivas Nannapaneni, Dongsheng Wang, Fakeng Liu, Xu Wang, Rui Jin, Xiuju Liu, Mohammad Aminur Rahman, Xianghong Peng, Guoqing Qian, Zhuo G. Chen, Kwok-Kin Wong, Fadlo R. Khuri, Wei Zhou, Dong M. Shin

Published Aug 1, 2017 · Vol. 8, No. 35 · pp. 59008-59022

GMI ablates cancer stemness and cisplatin resistance in oral carcinomas stem cells through IL-6/Stat3 signaling inhibition Research Paper

Tung Yuan Wang, Cheng-Chia Yu, Pei-Ling Hsieh, Yi-Wen Liao, Chuan-Hang Yu, Ming-Yung Chou

Published Jul 31, 2017 · Vol. 8, No. 41 · pp. 70422-70430

Early detection of thymidylate synthase resistance in non-small cell lung cancer with FLT-PET imaging Research Paper

Xiao Chen, Yizeng Yang, Sharyn Katz

Published Jul 31, 2017 · Vol. 8, No. 47 · pp. 82705-82713

Anti-cancer effects of dopamine in human glioma: involvement of mitochondrial apoptotic and anti-inflammatory pathways Research Paper

Yu-Long Lan, Xun Wang, Jin-Shan Xing, Zhen-Long Yu, Jia-Cheng Lou, Xiao-Chi Ma, Bo Zhang

Published Jul 29, 2017 · Vol. 8, No. 51 · pp. 88488-88500

Silencing heme oxygenase-1 increases the sensitivity of ABC-DLBCL cells to histone deacetylase inhibitor in vitro and in vivo Research Paper

Zhen Zhou, Qin Fang, Dan Ma, Nana Zhe, Mei Ren, Bingqing Cheng, Peifan Li, Ping Liu, Xiaojing Lin, Sishi Tang, Xiuying Hu, Yudan Liao, Yaming Zhang, Tingting Lu, Jishi Wang

Published Jul 28, 2017 · Vol. 8, No. 45 · pp. 78480-78495

Oligomer procyanidins (F2) repress HIF-1α expression in human U87 glioma cells by inhibiting the EGFR/ AKT/mTOR and MAPK/ERK1/2 signaling pathways in vitro and in vivo Research Paper

Hong-Li Zheng, Li-Hui Wang, Bao-Shan Sun, Yi Li, Jing-Yu Yang, Chun-Fu Wu

Published Jul 28, 2017 · Vol. 8, No. 49 · pp. 85252-85262

Patient-derived DIPG cells preserve stem-like characteristics and generate orthotopic tumors Research Paper

Cheng Xu, Xiaoqing Liu, Yibo Geng, Qingran Bai, Changcun Pan, Yu Sun, Xin Chen, Hai Yu, Yuliang Wu, Peng Zhang, Wenhao Wu, Yu Wang, Zhen Wu, Junting Zhang, Zhaohui Wang, Rui Yang, Jenna Lewis, Darell Bigner, Fangping Zhao, Yiping He, Hai Yan, Qin Shen, Liwei Zhang

Published Jul 28, 2017 · Vol. 8, No. 44 · pp. 76644-76655

N-myc downstream-regulated gene 1 promotes apoptosis in colorectal cancer via up-regulating death receptor 4 Research Paper

Xian Zhang, Bo Feng, Fan Zhu, Chaoran Yu, Jiaoyang Lu, Meng Pan, Zirui He, Xiongzhi Wangpu, Jing Sun, Xiao Yang

Published Jul 28, 2017 · Vol. 8, No. 47 · pp. 82593-82608

The addition of abemaciclib to sunitinib induces regression of renal cell carcinoma xenograft tumors Research Paper

Jeffrey Small, Erik Washburn, Karmaine Millington, Junjia Zhu, Sheldon L. Holder

Published Jul 27, 2017 · Vol. 8, No. 56 · pp. 95116-95134

Investigation of factors affecting the efficacy of 3C23K, a human monoclonal antibody targeting MISIIR Research Paper

Sarah E. Gill, Qing Zhang, Gary L. Keeney, William A. Cliby, S. John Weroha

Published Jul 27, 2017 · Vol. 8, No. 49 · pp. 85214-85223

Inhibition of chemerin/CMKLR1 axis in neuroblastoma cells reduces clonogenicity and cell viability in vitro and impairs tumor growth in vivo Research Paper

Conny TÃ¼mmler, Igor Snapkov, Malin WickstrÃ¶m, Ugo Moens, Linda Ljungblad, Lotta Helena Maria Elfman, Jan-Olof Winberg, Per Kogner, John Inge Johnsen, Baldur SveinbjÃ¸rnsson

Published Jul 27, 2017 · Vol. 8, No. 56 · pp. 95135-95151

Inhibition of LSD1 epigenetically attenuates oral cancer growth and metastasis Priority Research Paper

Saqer F. Alsaqer, Mustafa M. Tashkandi, Vinay K. Kartha, Ya-Ting Yang, Yazeed Alkheriji, Andrew Salama, Xaralabos Varelas, Maria Kukuruzinska, Stefano Monti, Manish V. Bais

Published Jul 27, 2017 · Vol. 8, No. 43 · pp. 73372-73386

Assessment of near-infrared fluorophores to study the biodistribution and tumor targeting of an IL13 receptor α2 antibody by fluorescence molecular tomography Research Paper

Parul Gupta, Jo-Ann Wentland, Mauricio Leal, Dangshe Ma, Rachel Roach, Antonio Esparza, Lindsay King, Mary E. Spilker, Cedo Bagi, Christopher T. Winkelmann, Anand Giddabasappa

Published Jul 26, 2017 · Vol. 8, No. 34 · pp. 57231-57245

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Targeting the cancer stem cell marker, aldehyde dehydrogenase 1, to circumvent cisplatin resistance in NSCLC Research Paper

The histone methyltransferase EZH2 as a druggable target in SHH medulloblastoma cancer stem cells Research Paper

Effect of weekly or daily dosing regimen of Gefitinib in mouse models of lung cancer Research Paper

IL-33 blockade suppresses tumor growth of human lung cancer through direct and indirect pathways in a preclinical model Research Paper

Antitumor efficacy of triple monoclonal antibody inhibition of epidermal growth factor receptor (EGFR) with MM151 in EGFR-dependent and in cetuximab-resistant human colorectal cancer cells Research Paper

Targeting the PI3K/AKT/mTOR signaling pathway as an effectively radiosensitizing strategy for treating human oral squamous cell carcinoma in vitro and in vivo Research Paper

Positive transcription elongation factor b (P-TEFb) is a therapeutic target in human multiple myeloma Research Paper

Phenformin enhances the therapeutic effect of selumetinib in KRAS-mutant non-small cell lung cancer irrespective of LKB1 status Research Paper

GMI ablates cancer stemness and cisplatin resistance in oral carcinomas stem cells through IL-6/Stat3 signaling inhibition Research Paper

Early detection of thymidylate synthase resistance in non-small cell lung cancer with FLT-PET imaging Research Paper

Anti-cancer effects of dopamine in human glioma: involvement of mitochondrial apoptotic and anti-inflammatory pathways Research Paper

Silencing heme oxygenase-1 increases the sensitivity of ABC-DLBCL cells to histone deacetylase inhibitor in vitro and in vivo Research Paper

Oligomer procyanidins (F2) repress HIF-1α expression in human U87 glioma cells by inhibiting the EGFR/ AKT/mTOR and MAPK/ERK1/2 signaling pathways in vitro and in vivo Research Paper

Patient-derived DIPG cells preserve stem-like characteristics and generate orthotopic tumors Research Paper

N-myc downstream-regulated gene 1 promotes apoptosis in colorectal cancer via up-regulating death receptor 4 Research Paper

The addition of abemaciclib to sunitinib induces regression of renal cell carcinoma xenograft tumors Research Paper

Investigation of factors affecting the efficacy of 3C23K, a human monoclonal antibody targeting MISIIR Research Paper

Inhibition of chemerin/CMKLR1 axis in neuroblastoma cells reduces clonogenicity and cell viability in vitro and impairs tumor growth in vivo Research Paper

Inhibition of LSD1 epigenetically attenuates oral cancer growth and metastasis Priority Research Paper

Assessment of near-infrared fluorophores to study the biodistribution and tumor targeting of an IL13 receptor α2 antibody by fluorescence molecular tomography Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Targeting the cancer stem cell marker, aldehyde dehydrogenase 1, to circumvent cisplatin resistance in NSCLC Research Paper

The histone methyltransferase EZH2 as a druggable target in SHH medulloblastoma cancer stem cells Research Paper

Effect of weekly or daily dosing regimen of Gefitinib in mouse models of lung cancer Research Paper

IL-33 blockade suppresses tumor growth of human lung cancer through direct and indirect pathways in a preclinical model Research Paper

Antitumor efficacy of triple monoclonal antibody inhibition of epidermal growth factor receptor (EGFR) with MM151 in EGFR-dependent and in cetuximab-resistant human colorectal cancer cells Research Paper

Targeting the PI3K/AKT/mTOR signaling pathway as an effectively radiosensitizing strategy for treating human oral squamous cell carcinoma in vitro and in vivo Research Paper

Positive transcription elongation factor b (P-TEFb) is a therapeutic target in human multiple myeloma Research Paper

Phenformin enhances the therapeutic effect of selumetinib in KRAS-mutant non-small cell lung cancer irrespective of LKB1 status Research Paper

GMI ablates cancer stemness and cisplatin resistance in oral carcinomas stem cells through IL-6/Stat3 signaling inhibition Research Paper

Early detection of thymidylate synthase resistance in non-small cell lung cancer with FLT-PET imaging Research Paper

Anti-cancer effects of dopamine in human glioma: involvement of mitochondrial apoptotic and anti-inflammatory pathways Research Paper

Silencing heme oxygenase-1 increases the sensitivity of ABC-DLBCL cells to histone deacetylase inhibitor in vitro and in vivo Research Paper

Oligomer procyanidins (F2) repress HIF-1α expression in human U87 glioma cells by inhibiting the EGFR/ AKT/mTOR and MAPK/ERK1/2 signaling pathways in vitro and in vivo Research Paper

Patient-derived DIPG cells preserve stem-like characteristics and generate orthotopic tumors Research Paper

N-myc downstream-regulated gene 1 promotes apoptosis in colorectal cancer via up-regulating death receptor 4 Research Paper

The addition of abemaciclib to sunitinib induces regression of renal cell carcinoma xenograft tumors Research Paper

Investigation of factors affecting the efficacy of 3C23K, a human monoclonal antibody targeting MISIIR Research Paper

Inhibition of chemerin/CMKLR1 axis in neuroblastoma cells reduces clonogenicity and cell viability in vitro and impairs tumor growth in vivo Research Paper

Inhibition of LSD1 epigenetically attenuates oral cancer growth and metastasis Priority Research Paper

Assessment of near-infrared fluorophores to study the biodistribution and tumor targeting of an IL13 receptor α2 antibody by fluorescence molecular tomography Research Paper