The Oncosearch | Oncotarget

Hyperactivation of Akt/mTOR and deficiency in tuberin increased the oxidative DNA damage in kidney cancer patients with diabetes Research Paper

Samy L. Habib, Sitai Liang

Published Mar 17, 2014 · Vol. 5, No. 9 · pp. 2542-2550

SLC25A1, or CIC, is a novel transcriptional target of mutant p53 and a negative tumor prognostic marker. Priority Research Paper

Vamsi K. Kolukula, Geetaram Sahu, Anton Wellstein, Olga C. Rodriguez, Anju Preet, Vito Iacobazzi, Gabriella D'Orazi, Chris Albanese, Ferdinando Palmieri, Maria Laura Avantaggiati

Published Mar 16, 2014 · Vol. 5, No. 5 · pp. 1212-1225

Dissecting the p53-Mdm2 feedback loop in vivo: uncoupling the role in p53 stability and activity Research Perspective

Vinod Pant, Guillermina Lozano

Published Mar 14, 2014 · Vol. 5, No. 5 · pp. 1149-1156

Role of aberrant PI3K pathway activation in gallbladder tumorigenesis Priority Research Paper

Andrea Lunardi, Kaitlyn A. Webster, Antonella Papa, Bhavik Padmani, John G. Clohessy, Roderick T. Bronson, Pier Paolo Pandolfi

Published Mar 10, 2014 · Vol. 5, No. 4 · pp. 894-900

A high-content morphological screen identifies novel microRNAs that regulate neuroblastoma cell differentiation Research Paper

Zhenze Zhao, Xiuye Ma, Tzu-Hung Hsiao, Gregory Lin, Adam Kosti, Xiaojie Yu, Uthra Suresh, Yidong Chen, Gail E. Tomlinson, Alexander Pertsemlidis, Liqin Du

Published Feb 28, 2014 · Vol. 5, No. 9 · pp. 2499-2512

Keywords: neuroblastoma, microRNA, high-content screen, differentiation, differentiation therapy

LIF promotes tumorigenesis and metastasis of breast cancer through the AKT-mTOR pathway Research Paper

Xiaoyan Li, Qifeng Yang, Haiyang Yu, Lihua Wu, Yuhan Zhao, Cen Zhang, Xuetian Yue, Zhen Liu, Hao Wu, Bruce G. Haffty, Zhaohui Feng, Wenwei Hu

Published Feb 15, 2014 · Vol. 5, No. 3 · pp. 788-801

Frequent L1 retrotranspositions originating from TTC28 in colorectal cancer Research Paper

Esa PitkÃ¤nen, Tatiana Cajuso, Riku Katainen, Eevi Kaasinen, Niko VÃ¤limÃ¤ki, Kimmo Palin, Jussi Taipale, Lauri A. Aaltonen, Outi Kilpivaara

Published Feb 14, 2014 · Vol. 5, No. 3 · pp. 853-859

Prostate cancer-derived CCN3 induces M2 macrophage infiltration and contributes to angiogenesis in prostate cancer microenvironment Research Paper

Po-Chun Chen, Hsu-Chen Cheng, John Wang, Shin-Wei Wang, Huai-Ching Tai, Chiao-Wen Lin, Chih-Hsin Tang

Published Feb 4, 2014 · Vol. 5, No. 6 · pp. 1595-1608

Keywords: CCN3, VEGF, Prostate cancer, M2 macrophage, angiogenesis

Role of the polypeptide N-acetylgalactosaminyltransferase 3 in ovarian cancer progression: possible implications in abnormal mucin O-glycosylation Research Paper

Zhi-Qiang Wang, Magdalena Bachvarova, Chantale Morin, Marie Plante, Jean Gregoire, Marie-Claude Renaud, Alexandra Sebastianelli, Dimcho Bachvarov

Published Jan 27, 2014 · Vol. 5, No. 2 · pp. 544-560

Keywords: GALNT3, epithelial ovarian cancer, DNA hypomethylation, progression-free survival, microarrays, mucin O-glycosylation

Hypoxia inducible factor-1 alpha as a therapeutic target in multiple myeloma Research Paper

Enrica Borsi, Giulia Perrone, Carolina Terragna, Marina Martello, Angela F Dico, Giancarlo Solaini, Alessandra Baracca, Gianluca Sgarbi, Gianandrea Pasquinelli, Sabrina Valente, Elena Zamagni, Paola Tacchetti, Giovanni Martinelli, Michele Cavo

Published Jan 23, 2014 · Vol. 5, No. 7 · pp. 1779-1792

Keywords: HIF-1Î±, Multiple Myeloma, Cell cycle, Mitochondria, Warburg effect

SCF^Î²-TRCP-mediated degradation of NEDD4 inhibits tumorigenesis through modulating the PTEN/Akt signaling pathway Research Paper

Jia Liu, Lixin Wan, Pengda Liu, Hiroyuki Inuzuka, Jiankang Liu, Zhiwei Wang, Wenyi Wei

Published Jan 20, 2014 · Vol. 5, No. 4 · pp. 1026-1037

Keywords: Î²-TRCP, NEDD4, degradation, PTEN, Akt, cancer, phosphorylation, ubiquitination, therapy

Interaction between the ADAMTS-12 metalloprotease and fibulin-2 induces tumor-suppressive effects in breast cancer cells Research Paper

Tania Fontanil, Susana Rua, Maria Llamazares, Angela Moncada-Pazos, Pedro M. Quiros, Olivia Garcia-Suarez, Jose A. Vega, Takako Sasaki, Yamina Mohamedi, Manuel M. Esteban, Alvaro J. Obaya, Santiago Cal

Published Jan 12, 2014 · Vol. 5, No. 5 · pp. 1253-1264

Keywords: extracellular matrix, metalloprotease, ADAMTS, fibulin, breast cancer

C-kit induces epithelialâ€“mesenchymal transition and contributes to salivary adenoid cystic cancer progression Research Paper

Ya-ling Tang, Yun-long Fan, Jian Jiang, Kai-de Li, Min Zheng, Wei Chen, Xiang-rui Ma, Ning Geng, Qian-ming Chen, Yu Chen, Xinhua Liang

Published Jan 6, 2014 · Vol. 5, No. 6 · pp. 1491-1501

Keywords: salivary adenoid cystic cancer, epithelialâ€“mesenchymal transition (EMT), c-kit, cancer stem cell, metastasis

FOXP3 over-expression inhibits melanoma tumorigenesis via effects on proliferation and apoptosis. Research Paper

Bee Shin Tan, Matthew R Anaka, Siddhartha Deb, Claudia Freyer, Lisa M Ebert, Anderly C Chueh, Sheren Al-Obaidi, Andreas Behren, Aparna Jayachandran, Jonathan Cebon, Weisan Chen, John M Mariadason

Published Dec 20, 2013 · Vol. 5, No. 1 · pp. 264-276

Keywords: FOXP3, melanoma, proliferation, apoptosis

A loss-of-function mutation in PTCH1 suggests a role for autocrine hedgehog signaling in colorectal tumorigenesis Brief Reports

Jon H. Chung, Fred Bunz

Published Dec 11, 2013 · Vol. 4, No. 12 · pp. 2208-2211

Keywords: Hedgehog, colorectal cancer, Patched, vismodegib, autocrine

The polycomb group protein EZH2 is a novel therapeutic target in tongue cancer Research Paper

Zhongwu li, Yanling Wang, Jing Qiu, Qiang Li, Chunping Yuan, Wei Zhang, Dongmiao Wang, Jinhai Ye, Hongbin Jiang, Jianrong Yang, Jie Cheng

Published Dec 7, 2013 · Vol. 4, No. 12 · pp. 2532-2549

Keywords: tongue squamous cell carcinoma, polycomb complex, EZH2, DZNep

The proto-oncogene KRAS is targeted by miR-200c Research Paper

Florian Kopp, Ernst Wagner, Andreas Roidl

Published Nov 24, 2013 · Vol. 5, No. 1 · pp. 185-195

Keywords: breast cancer, lung cancer, miRNA, K-ras, cell cycle, proliferation

COX-2 overexpression increases malignant potential of human glioma cells through Id1 Research Paper

Kaiming Xu, Lanfang Wang, Hui-Kuo G. Shu

Published Oct 31, 2013 · Vol. 5, No. 5 · pp. 1241-1252

Keywords: glioblastoma, brain tumor, tumorigenesis, cyclooxygenase-2, Id1

Cholesterol-induced mammary tumorigenesis is enhanced by adiponectin deficiency: role of LDL receptor upregulation Research Paper

Jing Liu, Aimin Xu, Karen Siu-Ling Lam, Nai-Sum Wong, Jie Chen, Peter R R Shepherd, Yu Wang

Published Oct 1, 2013 · Vol. 4, No. 10 · pp. 1804-1818

Keywords: Adiponectin, breast cancer, autophagy, cholesterol, LDLR

Upregulation of adenylate cyclase 3 (ADCY3) increases the tumorigenic potential of cells by activating the CREB pathway Research Paper

Seung-Hyun Hong, Sung-Ho Goh, Sang-Jin Lee, Jung-Ah Hwang, Jieun Lee, Il-Ju Choi, Hyehyun Seo, Jong-Hoon Park, Hiromu Suzuki, Eiichiro Yamamoto, In-Hoo Kim, Jin Sook Jeong, Mi Ha Ju, Dong-Hee Lee, Yeon-Su Lee

Published Sep 30, 2013 · Vol. 4, No. 10 · pp. 1791-1803

Keywords: gastric cancer, adenylate cyclase, tumorigenesis, cAMP/PKA/CREB pathway, promoter methylation

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Hyperactivation of Akt/mTOR and deficiency in tuberin increased the oxidative DNA damage in kidney cancer patients with diabetes Research Paper

SLC25A1, or CIC, is a novel transcriptional target of mutant p53 and a negative tumor prognostic marker. Priority Research Paper

Dissecting the p53-Mdm2 feedback loop in vivo: uncoupling the role in p53 stability and activity Research Perspective

Role of aberrant PI3K pathway activation in gallbladder tumorigenesis Priority Research Paper

A high-content morphological screen identifies novel microRNAs that regulate neuroblastoma cell differentiation Research Paper

LIF promotes tumorigenesis and metastasis of breast cancer through the AKT-mTOR pathway Research Paper

Frequent L1 retrotranspositions originating from TTC28 in colorectal cancer Research Paper

Prostate cancer-derived CCN3 induces M2 macrophage infiltration and contributes to angiogenesis in prostate cancer microenvironment Research Paper

Role of the polypeptide N-acetylgalactosaminyltransferase 3 in ovarian cancer progression: possible implications in abnormal mucin O-glycosylation Research Paper

Hypoxia inducible factor-1 alpha as a therapeutic target in multiple myeloma Research Paper

SCF^Î²-TRCP-mediated degradation of NEDD4 inhibits tumorigenesis through modulating the PTEN/Akt signaling pathway Research Paper

Interaction between the ADAMTS-12 metalloprotease and fibulin-2 induces tumor-suppressive effects in breast cancer cells Research Paper

C-kit induces epithelialâ€“mesenchymal transition and contributes to salivary adenoid cystic cancer progression Research Paper

FOXP3 over-expression inhibits melanoma tumorigenesis via effects on proliferation and apoptosis. Research Paper

A loss-of-function mutation in PTCH1 suggests a role for autocrine hedgehog signaling in colorectal tumorigenesis Brief Reports

The polycomb group protein EZH2 is a novel therapeutic target in tongue cancer Research Paper

The proto-oncogene KRAS is targeted by miR-200c Research Paper

COX-2 overexpression increases malignant potential of human glioma cells through Id1 Research Paper

Cholesterol-induced mammary tumorigenesis is enhanced by adiponectin deficiency: role of LDL receptor upregulation Research Paper

Upregulation of adenylate cyclase 3 (ADCY3) increases the tumorigenic potential of cells by activating the CREB pathway Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Hyperactivation of Akt/mTOR and deficiency in tuberin increased the oxidative DNA damage in kidney cancer patients with diabetes Research Paper

SLC25A1, or CIC, is a novel transcriptional target of mutant p53 and a negative tumor prognostic marker. Priority Research Paper

Dissecting the p53-Mdm2 feedback loop in vivo: uncoupling the role in p53 stability and activity Research Perspective

Role of aberrant PI3K pathway activation in gallbladder tumorigenesis Priority Research Paper

A high-content morphological screen identifies novel microRNAs that regulate neuroblastoma cell differentiation Research Paper

LIF promotes tumorigenesis and metastasis of breast cancer through the AKT-mTOR pathway Research Paper

Frequent L1 retrotranspositions originating from TTC28 in colorectal cancer Research Paper

Prostate cancer-derived CCN3 induces M2 macrophage infiltration and contributes to angiogenesis in prostate cancer microenvironment Research Paper

Role of the polypeptide N-acetylgalactosaminyltransferase 3 in ovarian cancer progression: possible implications in abnormal mucin O-glycosylation Research Paper

Hypoxia inducible factor-1 alpha as a therapeutic target in multiple myeloma Research Paper

SCFÎ²-TRCP-mediated degradation of NEDD4 inhibits tumorigenesis through modulating the PTEN/Akt signaling pathway Research Paper

Interaction between the ADAMTS-12 metalloprotease and fibulin-2 induces tumor-suppressive effects in breast cancer cells Research Paper

C-kit induces epithelialâ€“mesenchymal transition and contributes to salivary adenoid cystic cancer progression Research Paper

FOXP3 over-expression inhibits melanoma tumorigenesis via effects on proliferation and apoptosis. Research Paper

A loss-of-function mutation in PTCH1 suggests a role for autocrine hedgehog signaling in colorectal tumorigenesis Brief Reports

The polycomb group protein EZH2 is a novel therapeutic target in tongue cancer Research Paper

The proto-oncogene KRAS is targeted by miR-200c Research Paper

COX-2 overexpression increases malignant potential of human glioma cells through Id1 Research Paper

Cholesterol-induced mammary tumorigenesis is enhanced by adiponectin deficiency: role of LDL receptor upregulation Research Paper

Upregulation of adenylate cyclase 3 (ADCY3) increases the tumorigenic potential of cells by activating the CREB pathway Research Paper

SCF^Î²-TRCP-mediated degradation of NEDD4 inhibits tumorigenesis through modulating the PTEN/Akt signaling pathway Research Paper