The Oncosearch | Oncotarget

Computational prediction and experimental validation of a novel synthesized pan-PIM inhibitor PI003 and its apoptosis-inducing mechanisms in cervical cancer Research Paper

Zhongyu Liu, Weihua He, Jianglin Gao, Junhua Luo, Xian Huang, Chunfang Gao

Published Feb 4, 2015 · Vol. 6, No. 10 · pp. 8019-8035

Elevated S100A6 (Calcyclin) enhances tumorigenesis and suppresses CXCL14-induced apoptosis in clear cell renal cell carcinoma Research Paper

Xiang-Jun Lyu, Hong-Zhao Li, Xin Ma, Xin-Tao Li, Yu Gao, Dong Ni, Dong-Lai Shen, Liang-You Gu, Bao-Jun Wang, Yu Zhang, Xu Zhang

Published Feb 3, 2015 · Vol. 6, No. 9 · pp. 6656-6669

MicroRNA-153 promotes Wnt/Î²-catenin activation in hepatocellular carcinoma through suppression of WWOX Research Paper

Hong-Wei Hua, Feng Jiang, Qian Huang, Zhijun Liao, Gang Ding

Published Feb 2, 2015 · Vol. 6, No. 6 · pp. 3840-3847

Elevated NIBP/TRAPPC9 mediates tumorigenesis of cancer cells through NFÎºB signaling Research Paper

Yonggang Zhang, Shu Liu, Hong Wang, Wensheng Yang, Fang Li, Fan Yang, Daohai Yu, Frederick V. Ramsey, George P. Tuszyski, Wenhui Hu

Published Jan 31, 2015 · Vol. 6, No. 8 · pp. 6160-6178

CSN6 deregulation impairs genome integrity in a COP1-dependent pathway Priority Research Paper

Hyun Ho Choi, Chun-Hui Su, Lekun Fang, Jin Zhang, Sai-Ching J. Yeung, Mong-Hong Lee

Published Jan 31, 2015 · Vol. 6, No. 14 · pp. 11779-11793

Inhibition of Shp2 suppresses mutant EGFR-induced lung tumors in transgenic mouse model of lung adenocarcinoma Research Paper

Valentina E. Schneeberger, Yuan Ren, Noreen Luetteke, Qingling Huang, Liwei Chen, Harshani R. Lawrence, Nicholas J. Lawrence, Eric B. Haura, John M. Koomen, Domenico Coppola, Jie Wu

Published Jan 31, 2015 · Vol. 6, No. 8 · pp. 6191-6202

Function of phosphorylation of NF-kB p65 ser536 in prostate cancer oncogenesis Research Paper

Li Zhang, Longjiang Shao, Chad J. Creighton, Yiqun Zhang, Li Xin, Michael Ittmann, Jianghua Wang

Published Jan 31, 2015 · Vol. 6, No. 8 · pp. 6281-6294

Free ISG15 triggers an antitumor immune response against breast cancer: a new perspective Research Paper

Julian Burks, Ryan E. Reed, Shyamal D. Desai

Published Jan 31, 2015 · Vol. 6, No. 9 · pp. 7221-7231

Androgen receptor non-nuclear regulation of prostate cancer cell invasion mediated by Src and matriptase Research Paper

Jelani C. Zarif, Laura E. Lamb, Veronique S. Schulz, Eric A. Nollet, Cindy K. Miranti

Published Jan 29, 2015 · Vol. 6, No. 9 · pp. 6862-6876

Up-regulation of C1GALT1 promotes breast cancer cell growth through MUC1-C signaling pathway Research Paper

Chih-Hsing Chou, Miao-Juei Huang, Chi-Hau Chen, Ming-Kwang Shyu, John Huang, Ji-Shiang Hung, Chiun-Sheng Huang, Min-Chuan Huang

Published Jan 27, 2015 · Vol. 6, No. 8 · pp. 6123-6135

A new chemical inhibitor of angiogenesis and tumorigenesis that targets the VEGF signaling pathway upstream of Ras Research Paper

AgnÃ¨s Desroches-Castan, Delphine QuÃ©lard, Martine Demeunynck, Jean-FranÃ§ois Constant, Chongling Dong, Michelle Keramidas, Jean-Luc Coll, Caroline Barette, Laurence LafanechÃ¨re, Jean-Jacques Feige

Published Jan 23, 2015 · Vol. 6, No. 7 · pp. 5382-5411

Subthreshold IKK activation modulates the effector functions of primary mast cells and allows specific targeting of transformed mast cells Research Paper

Sebastian Drube, Franziska Weber, Romy Loschinski, Mandy Beyer, Mandy Rothe, Anja Rabenhorst, Christiane GÃ¶pfert, Isabel Meininger, Michaela A. Diamanti, David Stegner, Norman HÃ¤fner, Martin BÃ¶ttcher, Kirstin Reinecke, Thomas Herdegen, Florian R. Greten, Bernhard Nieswandt, Karin Hartmann, Oliver H. KrÃ¤mer, Thomas Kamradt

Published Jan 22, 2015 · Vol. 6, No. 7 · pp. 5354-5368

Notch3 functions as a regulator of cell self-renewal by interacting with the Î²-catenin pathway in hepatocellular carcinoma Research Paper

Qingyu Zhang, Caijie Lu, Tao Fang, Yongcun Wang, Wenhua Hu, Jie Qiao, Bin Liu, Jie Liu, Nianping Chen, Mingyi Li, Runzhi Zhu

Published Jan 21, 2015 · Vol. 6, No. 6 · pp. 3669-3679

Keywords: Notch3, Beta-catenin, cancer stem cells, hepatocellular carcinoma

Mucin1 shifts Smad3 signaling from the tumor-suppressive pSmad3C/p21^WAF1 pathway to the oncogenic pSmad3L/c-Myc pathway by activating JNK in human hepatocellular carcinoma cells Research Paper

Qiongshu Li, Guomu Liu, Hongyan Yuan, Juan Wang, Yingying Guo, Tanxiu Chen, Ruiping Zhai, Dan Shao, Weihua Ni, Guixiang Tai

Published Jan 20, 2015 · Vol. 6, No. 6 · pp. 4253-4265

IL-1RT1 signaling antagonizes IL-11 induced STAT3 dependent cardiac and antral stomach tumor development through myeloid cell enrichment Research Paper

Jon N Buzzelli, Dan I Pavlic, Heather V Chalinor, Louise Oâ€™Connor, Trevelyan R Menheniott, Andrew S Giraud, Louise M Judd

Published Jan 6, 2015 · Vol. 6, No. 2 · pp. 679-695

Keywords: Mucosal immunity, cancer immunobiology, cytokines, IL-11, STAT3, IL-1, MDSCs

The TRAF-interacting protein (TRAIP) is a novel E2F target with peak expression in mitosis Research Paper

Christophe Chapard, Daniel Hohl, Marcel Huber

Published Jan 2, 2015 · Vol. 6, No. 25 · pp. 20933-20945

The heparan sulfate mimetic PG545 interferes with Wnt/Î²-catenin signaling and significantly suppresses pancreatic tumorigenesis alone and in combination with gemcitabine Research Paper

Deok-Beom Jung, Miyong Yun, Eun-Ok Kim, Jaekwang Kim, Bonglee Kim, Ji Hoon Jung, Enfeng Wang, Debabrata Mukhopadhyay, Edward Hammond, Keith Dredge, Viji Shridhar, Sung-Hoon Kim

Published Dec 31, 2014 · Vol. 6, No. 7 · pp. 4992-5004

DEPTOR has growth suppression activity against pancreatic cancer cells Research Paper

Hua Li, Grace Y. Sun, Yongchao Zhao, Dafydd Thomas, Joel K. Greenson, Mark M. Zalupski, Edgar Ben-Josef, Yi Sun

Published Dec 30, 2014 · Vol. 5, No. 24 · pp. 12811-12819

Keywords: DEPTOR, mTOR pathway, pancreatic cancer, growth suppression

Advances in targeted therapies and new promising targets in esophageal cancer Review

Abbes Belkhiri, Wael El-Rifai

Published Dec 30, 2014 · Vol. 6, No. 3 · pp. 1348-1358

Keywords: adenocarcinoma, esophageal, gastric, cancer, targeted therapy

High expression of N-myc (and STAT) interactor predicts poor prognosis and promotes tumor growth in human glioblastoma Research Paper

Delong Meng, Yuanyuan Chen, Dapeng Yun, Yingjie Zhao, Jingkun Wang, Tao Xu, Xiaoying Li, Yuqi Wang, Li Yuan, Ruochuan Sun, Xiao Song, Cong Huai, Lingna Hu, Song Yang, Taishan Min, Juxiang Chen, Hongyan Chen, Daru Lu

Published Dec 30, 2014 · Vol. 6, No. 7 · pp. 4901-4919

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Computational prediction and experimental validation of a novel synthesized pan-PIM inhibitor PI003 and its apoptosis-inducing mechanisms in cervical cancer Research Paper

Elevated S100A6 (Calcyclin) enhances tumorigenesis and suppresses CXCL14-induced apoptosis in clear cell renal cell carcinoma Research Paper

MicroRNA-153 promotes Wnt/Î²-catenin activation in hepatocellular carcinoma through suppression of WWOX Research Paper

Elevated NIBP/TRAPPC9 mediates tumorigenesis of cancer cells through NFÎºB signaling Research Paper

CSN6 deregulation impairs genome integrity in a COP1-dependent pathway Priority Research Paper

Inhibition of Shp2 suppresses mutant EGFR-induced lung tumors in transgenic mouse model of lung adenocarcinoma Research Paper

Function of phosphorylation of NF-kB p65 ser536 in prostate cancer oncogenesis Research Paper

Free ISG15 triggers an antitumor immune response against breast cancer: a new perspective Research Paper

Androgen receptor non-nuclear regulation of prostate cancer cell invasion mediated by Src and matriptase Research Paper

Up-regulation of C1GALT1 promotes breast cancer cell growth through MUC1-C signaling pathway Research Paper

A new chemical inhibitor of angiogenesis and tumorigenesis that targets the VEGF signaling pathway upstream of Ras Research Paper

Subthreshold IKK activation modulates the effector functions of primary mast cells and allows specific targeting of transformed mast cells Research Paper

Notch3 functions as a regulator of cell self-renewal by interacting with the Î²-catenin pathway in hepatocellular carcinoma Research Paper

Mucin1 shifts Smad3 signaling from the tumor-suppressive pSmad3C/p21^WAF1 pathway to the oncogenic pSmad3L/c-Myc pathway by activating JNK in human hepatocellular carcinoma cells Research Paper

IL-1RT1 signaling antagonizes IL-11 induced STAT3 dependent cardiac and antral stomach tumor development through myeloid cell enrichment Research Paper

The TRAF-interacting protein (TRAIP) is a novel E2F target with peak expression in mitosis Research Paper

The heparan sulfate mimetic PG545 interferes with Wnt/Î²-catenin signaling and significantly suppresses pancreatic tumorigenesis alone and in combination with gemcitabine Research Paper

DEPTOR has growth suppression activity against pancreatic cancer cells Research Paper

Advances in targeted therapies and new promising targets in esophageal cancer Review

High expression of N-myc (and STAT) interactor predicts poor prognosis and promotes tumor growth in human glioblastoma Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Computational prediction and experimental validation of a novel synthesized pan-PIM inhibitor PI003 and its apoptosis-inducing mechanisms in cervical cancer Research Paper

Elevated S100A6 (Calcyclin) enhances tumorigenesis and suppresses CXCL14-induced apoptosis in clear cell renal cell carcinoma Research Paper

MicroRNA-153 promotes Wnt/Î²-catenin activation in hepatocellular carcinoma through suppression of WWOX Research Paper

Elevated NIBP/TRAPPC9 mediates tumorigenesis of cancer cells through NFÎºB signaling Research Paper

CSN6 deregulation impairs genome integrity in a COP1-dependent pathway Priority Research Paper

Inhibition of Shp2 suppresses mutant EGFR-induced lung tumors in transgenic mouse model of lung adenocarcinoma Research Paper

Function of phosphorylation of NF-kB p65 ser536 in prostate cancer oncogenesis Research Paper

Free ISG15 triggers an antitumor immune response against breast cancer: a new perspective Research Paper

Androgen receptor non-nuclear regulation of prostate cancer cell invasion mediated by Src and matriptase Research Paper

Up-regulation of C1GALT1 promotes breast cancer cell growth through MUC1-C signaling pathway Research Paper

A new chemical inhibitor of angiogenesis and tumorigenesis that targets the VEGF signaling pathway upstream of Ras Research Paper

Subthreshold IKK activation modulates the effector functions of primary mast cells and allows specific targeting of transformed mast cells Research Paper

Notch3 functions as a regulator of cell self-renewal by interacting with the Î²-catenin pathway in hepatocellular carcinoma Research Paper

Mucin1 shifts Smad3 signaling from the tumor-suppressive pSmad3C/p21WAF1 pathway to the oncogenic pSmad3L/c-Myc pathway by activating JNK in human hepatocellular carcinoma cells Research Paper

IL-1RT1 signaling antagonizes IL-11 induced STAT3 dependent cardiac and antral stomach tumor development through myeloid cell enrichment Research Paper

The TRAF-interacting protein (TRAIP) is a novel E2F target with peak expression in mitosis Research Paper

The heparan sulfate mimetic PG545 interferes with Wnt/Î²-catenin signaling and significantly suppresses pancreatic tumorigenesis alone and in combination with gemcitabine Research Paper

DEPTOR has growth suppression activity against pancreatic cancer cells Research Paper

Advances in targeted therapies and new promising targets in esophageal cancer Review

High expression of N-myc (and STAT) interactor predicts poor prognosis and promotes tumor growth in human glioblastoma Research Paper

Mucin1 shifts Smad3 signaling from the tumor-suppressive pSmad3C/p21^WAF1 pathway to the oncogenic pSmad3L/c-Myc pathway by activating JNK in human hepatocellular carcinoma cells Research Paper