The Oncosearch | Oncotarget

Efficacy and safety of buparlisib, a PI3K inhibitor, in patients with malignancies harboring a PI3K pathway activation: a phase 2, open-label, single-arm study Research Paper

Sarina A. Piha-Paul, Matthew H. Taylor, Daniel Spitz, Lee Schwartzberg, J. Thaddeus Beck, Todd M. Bauer, Funda Meric-Bernstam, Das Purkayastha, Linda Karpiak, Sebastian Szpakowski, Fadi Braiteh

Published Nov 5, 2019 · Vol. 10, No. 60 · pp. 6526-6535

Keywords: phosphatidylinositol 3-kinase pathway, buparlisib, advanced malignancies, molecular selection, tissue agnostic

Kallikrein 6 protease advances colon tumorigenesis via induction of the high mobility group A2 protein Research Paper

Hwudaurw Chen, Earlphia Sells, Ritu Pandey, Edward R. Abril, Chiu-Hsieh Hsu, Robert S. Krouse, Raymond B. Nagle, Georgios Pampalakis, Georgia Sotiropoulou, Natalia A. Ignatenko

Published Oct 22, 2019 · Vol. 10, No. 58 · pp. 6062-6078

Keywords: colorectal cancer, kallikrein-related peptidase 6 or KLK6, SMAD2/3, epithelial-mesenchymal transition, HMGA2

Dual-Targeting AKT2 and ERK in cancer stem-like cells in neuroblastoma Research Paper

Kwang Woon Kim, Julia Y. Kim, Jingbo Qiao, Rachael A. Clark, Camille M. Powers, Hernan Correa, Dai H. Chung

Published Sep 24, 2019 · Vol. 10, No. 54 · pp. 5645-5659

Keywords: chemotherapy, radiotherapy, resistance, AKT2, MAPK

Correction: The heparan sulfate mimetic PG545 interferes with Wnt/β-catenin signaling and significantly suppresses pancreatic tumorigenesis alone and in combination with gemcitabine Correction

Deok-Beom Jung, Miyong Yun, Eun-Ok Kim, Jaekwang Kim, Bonglee Kim, Ji Hoon Jung, Enfeng Wang, Debabrata Mukhopadhyay, Edward Hammond, Keith Dredge, Viji Shridhar, Sung-Hoon Kim

Published Sep 17, 2019 · Vol. 10, No. 54 · pp. 5669-5669

New insights into the genomic landscape of meningiomas identified FGFR3 in a subset of patients with favorable prognoses Research Paper

Aysha AlSahlawi, Rasha Aljelaify, Amna Magrashi, Mariam AlSaeed, Amal Almutairi, Fatimah Alqubaishi, Abdulellah Alturkistani, Abdullah AlObaid, Mohamed Abouelhoda, Latifa AlMubarak, Nada AlTassan, Malak Abedalthagafi

Published Sep 17, 2019 · Vol. 10, No. 53 · pp. 5549-5559

Keywords: meningioma, FGFR3, NGS, genomics, CNS

SMR peptide antagonizes mortalin promoted release of extracellular vesicles and affects mortalin protection from complement-dependent cytotoxicity in breast cancer cells and leukemia cells Research Paper

Ming-Bo Huang, Jennifer Y. Wu, James Lillard, Vincent C. Bond

Published Sep 10, 2019 · Vol. 10, No. 52 · pp. 5419-5438

Keywords: extracellular vesicles, mortalin, complement, SMR peptides, breast cancer

Dual-Targeting AKT2 and ERK in cancer stem-like cells in neuroblastoma Research Paper

Kwang Woon Kim, Julia Y. Kim, Jingbo Qiao, Rachael A. Clark, Camille M. Powers, Hernan Correa, Dai H. Chung

Published Sep 5, 2019

Keywords: chemotherapy, radiotherapy, resistance, AKT2, MAPK

Increased expression of cathepsin D is required for L1-mediated colon cancer progression Research Paper

Sayon Basu, Sanith Cheriyamundath, Nancy Gavert, Thomas Brabletz, Gal Haase, Avri Ben-Ze’ev

Published Aug 27, 2019 · Vol. 10, No. 50 · pp. 5217-5228

Keywords: L1, cathepsin D, colon cancer, metastasis, Wnt/β-catenin signaling

Folic acid supplementation acts as a chemopreventive factor in tumorigenesis of hepatocellular carcinoma by inducing H3K9Me2-dependent transcriptional repression of LCN2 Research Paper

Yin-Ling Zhang, Geng Xue, Hui Miao, Chuan-Chuan Zhou, Shu-Han Sun, Yi Zhang

Published Jul 29, 2019 · Vol. 12, No. 4 · pp. 366-378

Keywords: folic acid, hepatocarcinogenesis, chemoprevention, LCN2, H3K9Me2

ETHE1 overexpression promotes SIRT1 and PGC1α mediated aerobic glycolysis, oxidative phosphorylation, mitochondrial biogenesis and colorectal cancer Research Paper

Mavee Witherspoon, Davinder Sandu, Changyuan Lu, Kehui Wang, Robert Edwards, Anthony Yeung, Ozkan Gelincik, Giovanni Manfredi, Steven Gross, Levy Kopelovich, Steven Lipkin

Published Jun 18, 2019 · Vol. 10, No. 40 · pp. 4004-4017

Keywords: familial adenomatous polyposis, ethylmalonic encephalopathy 1, mitochondrial bioenergetics, aerobic glycolysis, colorectal cancer

Functional interplay between YY1 and CARM1 promotes oral carcinogenesis Research Paper

Amit K. Behera, Manoj Kumar, Muthu K. Shanmugam, Aditya Bhattacharya, Vinay J. Rao, Akshay Bhat, Madavan Vasudevan, Kodaganur S. Gopinath, Azeem Mohiyuddin, Anupam Chatterjee, Gautam Sethi, Tapas K. Kundu

Published Jun 4, 2019 · Vol. 10, No. 38 · pp. 3709-3724

Keywords: oral cancer, oncogene, YY1, CARM1, arginine methylation

circPSMC3: ceRNA and tumor suppressor Editorial

Chen Lu, Dawei Rong, Weiwei Tang

Published May 11, 2019 · Vol. 10, No. 37 · pp. 3433-3434

Keywords: circRNAs, gastric cancer, sponge, biomarker

Bazedoxifene as a novel strategy for treatment of pancreatic and gastric adenocarcinoma Research Paper

Claudia Burkhardt, Leo Bühler, Matthieu Tihy, Philippe Morel, Michel Forni

Published May 7, 2019 · Vol. 10, No. 34 · pp. 3198-3202

Keywords: cytokine receptor GP130, gastric adenocarcinoma, pancreatic adenocarcinoma, selective estrogene receptor modulator, STAT transcription factors

Septin-2 is overexpressed in epithelial ovarian cancer and mediates proliferation via regulation of cellular metabolic proteins Research Paper

Nicole E. James, Evelyn Cantillo, Naohiro Yano, Clinton O. Chichester, Paul A. DiSilvestro, Virginia Hovanesian, R. Shyama Prasad Rao, Kyukwang K. Kim, Richard G. Moore, Nagib Ahsan, Jennifer R. Ribeiro

Published Apr 26, 2019 · Vol. 10, No. 31 · pp. 2959-2972

Keywords: ovarian cancer, proteomics, septin-2, metabolic proteins

MEF-2 isoformsâ€™ (A-D) roles in development and tumorigenesis Review

Kiran Madugula, Ria Mulherkar, Zafar K. Khan, DeGaulle I. Chigbu, Dip Patel, Edward W. Harhaj, Pooja Jain

Published Apr 12, 2019 · Vol. 10, No. 28 · pp. 2755-2787

Characterization of cancer-associated IDH2 mutations that differ in tumorigenicity, chemosensitivity and 2-hydroxyglutarate production Research Paper

Kevin P. Kotredes, Roshanak Razmpour, Evan Lutton, Mercedes Alfonso-Prieto, Servio H. Ramirez, Ana M. Gamero

Published Apr 12, 2019 · Vol. 10, No. 28 · pp. 2675-2692

Keywords: glioblastoma, IDH2, tumorigenesis, chemotherapy, biomarker

MicroRNA profiling of pancreatic ductal adenocarcinoma (PDAC) reveals signature expression related to lymph node metastasis Research Paper

Moran Lemberger, Shelly Loewenstein, Nir Lubezky, Eran Nizri, Metsada Pasmanik-Chor, Eli Barazovsky, Joseph M. Klausner, Guy Lahat

Published Apr 5, 2019 · Vol. 10, No. 27 · pp. 2644-2656

Co-localization of autophagy-related protein p62 with cancer stem cell marker dclk1 may hamper dclk1’s elimination during colon cancer development and progression Research Paper

Badal Chandra Roy, Ishfaq Ahmed, Satish Ramalingam, Venkatakrishna Jala, Bodduluri Haribabu, Prabhu Ramamoorthy, John Ashcraft, Joseph Valentino, Shrikant Anant, Venkatesh Sampath, Shahid Umar

Published Mar 22, 2019 · Vol. 10, No. 24 · pp. 2340-2354

Microarray and pathway analysis of two COMMA-DÎ² derived clones reveal important differences relevant to their developmental capacity in-vivo Research Paper

Jabril R. Johnson, Corinne A. Boulanger, Tamaro Hudson, Evan Savage, Gilbert H. Smith

Published Mar 15, 2019 · Vol. 10, No. 22 · pp. 2118-2135

CD164 regulates proliferation, progression, and invasion of human glioblastoma cells Research Paper

Chung-Ching Wang, Dueng-Yuan Hueng, Ai-Fang Huang, Wei-Liang Chen, Shih-Ming Huang, James Yi-Hsin Chan

Published Mar 12, 2019 · Vol. 10, No. 21 · pp. 2041-2054

Keywords: CD164, human glioma, glioblastoma, autophagy

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Efficacy and safety of buparlisib, a PI3K inhibitor, in patients with malignancies harboring a PI3K pathway activation: a phase 2, open-label, single-arm study Research Paper

Kallikrein 6 protease advances colon tumorigenesis via induction of the high mobility group A2 protein Research Paper

Dual-Targeting AKT2 and ERK in cancer stem-like cells in neuroblastoma Research Paper

Correction: The heparan sulfate mimetic PG545 interferes with Wnt/β-catenin signaling and significantly suppresses pancreatic tumorigenesis alone and in combination with gemcitabine Correction

New insights into the genomic landscape of meningiomas identified FGFR3 in a subset of patients with favorable prognoses Research Paper

SMR peptide antagonizes mortalin promoted release of extracellular vesicles and affects mortalin protection from complement-dependent cytotoxicity in breast cancer cells and leukemia cells Research Paper

Dual-Targeting AKT2 and ERK in cancer stem-like cells in neuroblastoma Research Paper

Increased expression of cathepsin D is required for L1-mediated colon cancer progression Research Paper

Folic acid supplementation acts as a chemopreventive factor in tumorigenesis of hepatocellular carcinoma by inducing H3K9Me2-dependent transcriptional repression of LCN2 Research Paper

ETHE1 overexpression promotes SIRT1 and PGC1α mediated aerobic glycolysis, oxidative phosphorylation, mitochondrial biogenesis and colorectal cancer Research Paper

Functional interplay between YY1 and CARM1 promotes oral carcinogenesis Research Paper

circPSMC3: ceRNA and tumor suppressor Editorial

Bazedoxifene as a novel strategy for treatment of pancreatic and gastric adenocarcinoma Research Paper

Septin-2 is overexpressed in epithelial ovarian cancer and mediates proliferation via regulation of cellular metabolic proteins Research Paper

MEF-2 isoformsâ€™ (A-D) roles in development and tumorigenesis Review

Characterization of cancer-associated IDH2 mutations that differ in tumorigenicity, chemosensitivity and 2-hydroxyglutarate production Research Paper

MicroRNA profiling of pancreatic ductal adenocarcinoma (PDAC) reveals signature expression related to lymph node metastasis Research Paper

Co-localization of autophagy-related protein p62 with cancer stem cell marker dclk1 may hamper dclk1’s elimination during colon cancer development and progression Research Paper

Microarray and pathway analysis of two COMMA-DÎ² derived clones reveal important differences relevant to their developmental capacity in-vivo Research Paper

CD164 regulates proliferation, progression, and invasion of human glioblastoma cells Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Efficacy and safety of buparlisib, a PI3K inhibitor, in patients with malignancies harboring a PI3K pathway activation: a phase 2, open-label, single-arm study Research Paper

Kallikrein 6 protease advances colon tumorigenesis via induction of the high mobility group A2 protein Research Paper

Dual-Targeting AKT2 and ERK in cancer stem-like cells in neuroblastoma Research Paper

Correction: The heparan sulfate mimetic PG545 interferes with Wnt/β-catenin signaling and significantly suppresses pancreatic tumorigenesis alone and in combination with gemcitabine Correction

New insights into the genomic landscape of meningiomas identified FGFR3 in a subset of patients with favorable prognoses Research Paper

SMR peptide antagonizes mortalin promoted release of extracellular vesicles and affects mortalin protection from complement-dependent cytotoxicity in breast cancer cells and leukemia cells Research Paper

Dual-Targeting AKT2 and ERK in cancer stem-like cells in neuroblastoma Research Paper

Increased expression of cathepsin D is required for L1-mediated colon cancer progression Research Paper

Folic acid supplementation acts as a chemopreventive factor in tumorigenesis of hepatocellular carcinoma by inducing H3K9Me2-dependent transcriptional repression of LCN2 Research Paper

ETHE1 overexpression promotes SIRT1 and PGC1α mediated aerobic glycolysis, oxidative phosphorylation, mitochondrial biogenesis and colorectal cancer Research Paper

Functional interplay between YY1 and CARM1 promotes oral carcinogenesis Research Paper

circPSMC3: ceRNA and tumor suppressor Editorial

Bazedoxifene as a novel strategy for treatment of pancreatic and gastric adenocarcinoma Research Paper

Septin-2 is overexpressed in epithelial ovarian cancer and mediates proliferation via regulation of cellular metabolic proteins Research Paper

MEF-2 isoformsâ€™ (A-D) roles in development and tumorigenesis Review

Characterization of cancer-associated IDH2 mutations that differ in tumorigenicity, chemosensitivity and 2-hydroxyglutarate production Research Paper

MicroRNA profiling of pancreatic ductal adenocarcinoma (PDAC) reveals signature expression related to lymph node metastasis Research Paper

Co-localization of autophagy-related protein p62 with cancer stem cell marker dclk1 may hamper dclk1’s elimination during colon cancer development and progression Research Paper

Microarray and pathway analysis of two COMMA-DÎ² derived clones reveal important differences relevant to their developmental capacity in-vivo Research Paper

CD164 regulates proliferation, progression, and invasion of human glioblastoma cells Research Paper