The Oncosearch | Oncotarget

Sonic hedgehog inhibitors prevent colitis-associated cancer via orchestrated mechanisms of IL-6/gp130 inhibition, 15-PGDH induction, Bcl-2 abrogation, and tumorsphere inhibition Research Paper

Napapan Kangwan, Yoon-Jae Kim, Young Min Han, Migyeong Jeong, Jong-Min Park, Eun-Jin Go, Ki-Baik Hahm

Published Dec 26, 2015 · Vol. 7, No. 7 · pp. 7667-7682

Simultaneous gene silencing of KRAS and anti-apoptotic genes as a multitarget therapy Research Paper

Kristin Werner, Franziska Lademann, May-Linn Thepkaysone, Beatrix Jahnke, Daniela E. Aust, Christoph Kahlert, Georg Weber, JÃ¼rgen Weitz, Robert GrÃ¼tzmann, Christian Pilarsky

Published Dec 26, 2015 · Vol. 7, No. 4 · pp. 3984-3992

Enhanced expression of LINE-1-encoded ORF2 protein in early stages of colon and prostate transformation Research Paper

Chiara De Luca, Fiorella Guadagni, Paola Sinibaldi-Vallebona, Steno Sentinelli, Michele Gallucci, Andreas Hoffmann, Gerald G. Schumann, Corrado Spadafora, Ilaria Sciamanna

Published Dec 26, 2015 · Vol. 7, No. 4 · pp. 4048-4061

Combination therapy of RY10-4 with the Î³-secretase inhibitor DAPT shows promise in treating HER2-amplified breast cancer Research Paper

Feng Su, Shilin Zhu, Jinlan Ruan, Yagmur Muftuoglu, Longbo Zhang, Qianying Yuan

Published Dec 26, 2015 · Vol. 7, No. 4 · pp. 4142-4154

High efficacy of third generation EGFR inhibitor AZD9291 in a leptomeningeal carcinomatosis model with EGFR-mutant lung cancer cells Research Paper

Shigeki Nanjo, Hiromichi Ebi, Sachiko Arai, Shinji Takeuchi, Tadaaki Yamada, Satsuki Mochizuki, Yasunori Okada, Mitsutoshi Nakada, Takashi Murakami, Seiji Yano

Published Dec 24, 2015 · Vol. 7, No. 4 · pp. 3847-3856

Clusterin induced by N,Nâ€™-Dinitrosopiperazine is involved in nasopharyngeal carcinoma metastasis Research Paper

Yuejin Li, Jinping Lu, Shan Zhou, Weiwei Wang, Gongjun Tan, Zhenlin Zhang, Zigang Dong, Tiebang Kang, Faqing Tang

Published Dec 24, 2015 · Vol. 7, No. 5 · pp. 5548-5563

Overexpression of miR-199a-5p decreases esophageal cancer cell proliferation through repression of mitogen-activated protein kinase kinase kinase-11 (MAP3K11) Research Paper

Kimberly A. Byrnes, Pornima Phatak, Daniel Mansour, Lan Xiao, Tongtong Zou, Jaladanki N. Rao, Douglas J. Turner, Jian-Ying Wang, James M. Donahue

Published Dec 24, 2015 · Vol. 7, No. 8 · pp. 8756-8770

Serum level of hepatocyte growth factor is a novel marker of predicting the outcome and resistance to the treatment with trastuzumab in HER2-positive patients with metastatic gastric cancer Research Paper

Naoki Takahashi, Koh Furuta, Hirokazu Taniguchi, Yusuke Sasaki, Hirokazu Shoji, Yoshitaka Honma, Satoru Iwasa, Natsuko Okita, Atsuo Takashima, Ken Kato, Tetsuya Hamaguchi, Yasuhiro Shimada, Yasuhide Yamada

Published Dec 24, 2015 · Vol. 7, No. 4 · pp. 4925-4938

Leukemia inhibitory factor promotes EMT through STAT3-dependent miR-21 induction Research Paper

Xuetian Yue, Yuhan Zhao, Cen Zhang, Jun Li, Zhen Liu, Juan Liu, Wenwei Hu

Published Dec 24, 2015 · Vol. 7, No. 4 · pp. 3777-3790

Positive intratumoral chemokine (C-C motif) receptor 8 expression predicts high recurrence risk of post-operation clear-cell renal cell carcinoma patients Clinical Research Papers

Qiang Fu, Yuan Chang, Lin Zhou, Huimin An, Yu Zhu, Le Xu, Weijuan Zhang, Jiejie Xu

Published Dec 24, 2015 · Vol. 7, No. 7 · pp. 8413-8421

miR-215 promotes malignant progression of gastric cancer by targeting RUNX1 Research Paper

Na Li, Qi-Yue Zhang, Jian-Ling Zou, Zhong-Wu Li, Tian-Tian Tian, Bin Dong, Xi-Juan Liu, Sai Ge, Yan Zhu, Jing Gao, Lin Shen

Published Dec 23, 2015 · Vol. 7, No. 4 · pp. 4817-4828

Negative regulation of Bmi-1 by AMPK and implication in cancer progression Research Paper

Deqiang Huang, Xiaoling He, Junrong Zou, Pei Guo, Shanshan Jiang, Nonghua Lv, Yuriy Alekseyev, Lingyu Luo, Zhijun Luo

Published Dec 23, 2015 · Vol. 7, No. 5 · pp. 6188-6200

MicroRNA-584-3p, a novel tumor suppressor and prognostic marker, reduces the migration and invasion of human glioma cells by targeting hypoxia-induced ROCK1 Research Paper

Hao Xue, Xing Guo, Xiao Han, Shaofeng Yan, Jinsen Zhang, Shugang Xu, Tong Li, Xiaofan Guo, Ping Zhang, Xiao Gao, Qinglin Liu, Gang Li

Published Dec 23, 2015 · Vol. 7, No. 4 · pp. 4785-4805

TMSB4Y is a candidate tumor suppressor on the Y chromosome and is deleted in male breast cancer Research Paper

Hong Yuen Wong, Grace M. Wang, Sarah Croessmann, Daniel J. Zabransky, David Chu, Joseph P. Garay, Justin Cidado, Rory L. Cochran, Julia A. Beaver, Anita Aggarwal, Min-Ling Liu, Pedram Argani, Alan Meeker, Paula J. Hurley, Josh Lauring, Ben Ho Park

Published Dec 23, 2015 · Vol. 6, No. 42 · pp. 44927-44940

Kupffer cells-dependent inflammation in the injured liver increases recruitment of mesenchymal stem cells in aging mice Research Paper

Xue Yang, Lei Liang, Chen Zong, Fobao Lai, Pengxi Zhu, Yu Liu, Jinghua Jiang, Yang Yang, Lu Gao, Fei Ye, Qiudong Zhao, Rong Li, Zhipeng Han, Lixin Wei

Published Dec 23, 2015 · Vol. 7, No. 2 · pp. 1084-1095

Adenovirus-mediated delivery of herpes simplex virus thymidine kinase administration improves outcome of recurrent high-grade glioma Research Paper

Nan Ji, Danhui Weng, Cang Liu, Zheng Gu, Shizhang Chen, Ying Guo, Zhong Fan, Xiao Wang, Jianfei Chen, Yanyan Zhao, Jianfeng Zhou, Jisheng Wang, Ding Ma, Ning Li

Published Dec 23, 2015 · Vol. 7, No. 4 · pp. 4369-4378

A subset of myofibroblastic cancer-associated fibroblasts regulate collagen fiber elongation, which is prognostic in multiple cancers Research Paper

Christopher J. Hanley, Fergus Noble, Matthew Ward, Marc Bullock, Cole Drifka, Massimiliano Mellone, Antigoni Manousopoulou, Harvey E. Johnston, Annette Hayden, Steve Thirdborough, Yuming Liu, David M. Smith, Toby Mellows, W. John Kao, Spiros D. Garbis, Alex Mirnezami, Tim J. Underwood, Kevin W. Eliceiri, Gareth J. Thomas

Published Dec 23, 2015 · Vol. 7, No. 5 · pp. 6159-6174

High expression levels of MAGE-A9 are correlated with unfavorable survival in lung adenocarcinoma Research Paper

Xiaolu Zhai, Liqin Xu, Siya Zhang, Huijun Zhu, Guoxin Mao, Jianfei Huang

Published Dec 23, 2015 · Vol. 7, No. 4 · pp. 4871-4881

Loss of CtIP disturbs homologous recombination repair and sensitizes breast cancer cells to PARP inhibitors Research Paper

Junhui Wang, Qianshan Ding, Hiroaki Fujimori, Akira Motegi, Yoshio Miki, Mitsuko Masutani

Published Dec 22, 2015 · Vol. 7, No. 7 · pp. 7701-7714

Polycomb repressor complex 1 promotes gene silencing through H2AK119 mono-ubiquitination in acinar-to-ductal metaplasia and pancreatic cancer cells Research Paper

Simone Benitz, Ivonne Regel, Tobias Reinhard, Anna Popp, Isabell SchÃ¤ffer, Susanne Raulefs, Bo Kong, Irene Esposito, Christoph W. Michalski, JÃ¶rg Kleeff

Published Dec 22, 2015 · Vol. 7, No. 10 · pp. 11424-11433

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Sonic hedgehog inhibitors prevent colitis-associated cancer via orchestrated mechanisms of IL-6/gp130 inhibition, 15-PGDH induction, Bcl-2 abrogation, and tumorsphere inhibition Research Paper

Simultaneous gene silencing of KRAS and anti-apoptotic genes as a multitarget therapy Research Paper

Enhanced expression of LINE-1-encoded ORF2 protein in early stages of colon and prostate transformation Research Paper

Combination therapy of RY10-4 with the Î³-secretase inhibitor DAPT shows promise in treating HER2-amplified breast cancer Research Paper

High efficacy of third generation EGFR inhibitor AZD9291 in a leptomeningeal carcinomatosis model with EGFR-mutant lung cancer cells Research Paper

Clusterin induced by N,Nâ€™-Dinitrosopiperazine is involved in nasopharyngeal carcinoma metastasis Research Paper

Overexpression of miR-199a-5p decreases esophageal cancer cell proliferation through repression of mitogen-activated protein kinase kinase kinase-11 (MAP3K11) Research Paper

Serum level of hepatocyte growth factor is a novel marker of predicting the outcome and resistance to the treatment with trastuzumab in HER2-positive patients with metastatic gastric cancer Research Paper

Leukemia inhibitory factor promotes EMT through STAT3-dependent miR-21 induction Research Paper

Positive intratumoral chemokine (C-C motif) receptor 8 expression predicts high recurrence risk of post-operation clear-cell renal cell carcinoma patients Clinical Research Papers

miR-215 promotes malignant progression of gastric cancer by targeting RUNX1 Research Paper

Negative regulation of Bmi-1 by AMPK and implication in cancer progression Research Paper

MicroRNA-584-3p, a novel tumor suppressor and prognostic marker, reduces the migration and invasion of human glioma cells by targeting hypoxia-induced ROCK1 Research Paper

TMSB4Y is a candidate tumor suppressor on the Y chromosome and is deleted in male breast cancer Research Paper

Kupffer cells-dependent inflammation in the injured liver increases recruitment of mesenchymal stem cells in aging mice Research Paper

Adenovirus-mediated delivery of herpes simplex virus thymidine kinase administration improves outcome of recurrent high-grade glioma Research Paper

A subset of myofibroblastic cancer-associated fibroblasts regulate collagen fiber elongation, which is prognostic in multiple cancers Research Paper

High expression levels of MAGE-A9 are correlated with unfavorable survival in lung adenocarcinoma Research Paper

Loss of CtIP disturbs homologous recombination repair and sensitizes breast cancer cells to PARP inhibitors Research Paper

Polycomb repressor complex 1 promotes gene silencing through H2AK119 mono-ubiquitination in acinar-to-ductal metaplasia and pancreatic cancer cells Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Sonic hedgehog inhibitors prevent colitis-associated cancer via orchestrated mechanisms of IL-6/gp130 inhibition, 15-PGDH induction, Bcl-2 abrogation, and tumorsphere inhibition Research Paper

Simultaneous gene silencing of KRAS and anti-apoptotic genes as a multitarget therapy Research Paper

Enhanced expression of LINE-1-encoded ORF2 protein in early stages of colon and prostate transformation Research Paper

Combination therapy of RY10-4 with the Î³-secretase inhibitor DAPT shows promise in treating HER2-amplified breast cancer Research Paper

High efficacy of third generation EGFR inhibitor AZD9291 in a leptomeningeal carcinomatosis model with EGFR-mutant lung cancer cells Research Paper

Clusterin induced by N,Nâ€™-Dinitrosopiperazine is involved in nasopharyngeal carcinoma metastasis Research Paper

Overexpression of miR-199a-5p decreases esophageal cancer cell proliferation through repression of mitogen-activated protein kinase kinase kinase-11 (MAP3K11) Research Paper

Serum level of hepatocyte growth factor is a novel marker of predicting the outcome and resistance to the treatment with trastuzumab in HER2-positive patients with metastatic gastric cancer Research Paper

Leukemia inhibitory factor promotes EMT through STAT3-dependent miR-21 induction Research Paper

Positive intratumoral chemokine (C-C motif) receptor 8 expression predicts high recurrence risk of post-operation clear-cell renal cell carcinoma patients Clinical Research Papers

miR-215 promotes malignant progression of gastric cancer by targeting RUNX1 Research Paper

Negative regulation of Bmi-1 by AMPK and implication in cancer progression Research Paper

MicroRNA-584-3p, a novel tumor suppressor and prognostic marker, reduces the migration and invasion of human glioma cells by targeting hypoxia-induced ROCK1 Research Paper

TMSB4Y is a candidate tumor suppressor on the Y chromosome and is deleted in male breast cancer Research Paper

Kupffer cells-dependent inflammation in the injured liver increases recruitment of mesenchymal stem cells in aging mice Research Paper

Adenovirus-mediated delivery of herpes simplex virus thymidine kinase administration improves outcome of recurrent high-grade glioma Research Paper

A subset of myofibroblastic cancer-associated fibroblasts regulate collagen fiber elongation, which is prognostic in multiple cancers Research Paper

High expression levels of MAGE-A9 are correlated with unfavorable survival in lung adenocarcinoma Research Paper

Loss of CtIP disturbs homologous recombination repair and sensitizes breast cancer cells to PARP inhibitors Research Paper

Polycomb repressor complex 1 promotes gene silencing through H2AK119 mono-ubiquitination in acinar-to-ductal metaplasia and pancreatic cancer cells Research Paper