The Oncosearch | Oncotarget

Calcium signaling induced by 15-deoxy-prostamide-J₂ promotes cell death by activating PERK, IP3R, and the mitochondrial permeability transition pore Research Paper

Daniel A. Ladin, Margaret M. Nelson, Estefani Cota, Catherine Colonna, Colin Burns, Jacques Robidoux, Kelsey H. Fisher-Wellman, Rukiyah Van Dross-Anderson

Published Dec 14, 2022 · Vol. 13, No. 1 · pp. 1380-1396

Keywords: calcium, mitochondrial respiration, endoplasmic reticulum stress, cancer, prostamide

Anti-tumor effect of antibody drug conjugate ASP1235 targeting Fms-like tyrosine kinase 3 with venetoclax plus azacitidine in an acute myeloid leukemia xenograft mouse model Research Paper

Hirofumi Tsuzuki, Tatsuya Kawase, Taisuke Nakazawa, Masamichi Mori, Taku Yoshida

Published Dec 13, 2022 · Vol. 13, No. 1 · pp. 1359-1368

Keywords: acute myeloid leukemia (AML), ASP1235, antibody drug conjugate (ADC), venetoclax, azacitidine

Resistance of MMTV-NeuT/ATTAC mice to anti-PD-1 immune checkpoint therapy is associated with macrophage infiltration and Wnt pathway expression Research Paper

Hongyan Yuan, Lu Jin, Handan Xiang, Anannya Bhattacharya, Philip E. Brandish, Gretchen Baltus, Alexander Tong, Changyan Zhou, Robert I. Glazer

Published Dec 10, 2022 · Vol. 13, No. 1 · pp. 1350-1358

Keywords: PD-1, NeuT, Wnt, macrophages, mammary tumorigenesis

Addendum: Real-world survival analysis by tumor mutational burden in non-small cell lung cancer: a multisite U.S. study Addendum

Connor Willis, Hillevi Bauer, Trang H. Au, Jyothi Menon, Sudhir Unni, Dao Tran, Zachary Rivers, Wallace Akerley, Matthew B. Schabath, Firas Badin, Ashley Sekhon, Malini Patel, Bing Xia, Beth Gustafson, John L. Villano, John-Michael Thomas, Solomon J. Lubinga, Michael A. Cantrell, Diana Brixner, David Stenehjem

Published Nov 18, 2022 · Vol. 13, No. 1 · pp. 1306-1306

Addendum: Hyperprogression and impact of tumor growth kinetics after PD1/PDL1 inhibition in head and neck squamous cell carcinoma Addendum

Andy Karabajakian, Thibaut Garrivier, Carole Crozes, Nicolas Gadot, Jean-Yves Blay, Frédéric Bérard, Philippe Céruse, Philippe Zrounba, Pierre Saintigny, Charles Mastier, Jérôme Fayette

Published Nov 18, 2022 · Vol. 13, No. 1 · pp. 1305-1305

Mutation analysis performed on tumor biopsies from patients with newly-diagnosed germinal center aggressive B cell lymphomas Research Paper

Daniel J. Landsburg, Jennifer J.D. Morrissette, Stephen J. Schuster, Sunita D. Nasta, James N. Gerson, Stefan K. Barta, Jakub Svoboda, Elise A. Chong, Megan S. Lim

Published Nov 5, 2022 · Vol. 13, No. 1 · pp. 1237-1244

Keywords: diffuse large B cell lymphoma, high grade B cell lymphoma, mutation analysis, next generation sequencing, chemotherapy

Treasures from trash in cancer research Research Perspective

Fabiano Cordeiro Moreira, Dionison Pereira Sarquis, Jorge Estefano Santana de Souza, Daniel de Souza Avelar, Taíssa Maria Thomaz Araújo, André Salim Khayat, Sidney Emanuel Batista dos Santos, Paulo Pimentel de Assumpção

Published Nov 4, 2022 · Vol. 13, No. 1 · pp. 1246-1257

Keywords: cancer metagenomics, cancer sncRNA expression, RNA-Seq variant calling

Retraction: SAMMSON drives the self-renewal of liver tumor initiating cells through EZH2-dependent Wnt/β-catenin activation Retraction

Xiaopeng Li, Ming Li, JiaLi Chen, Hua Dai, Liang Wang, Ying Xiong, Yuanbin Zhong, Lunli Zhang

Published Nov 2, 2022 · Vol. 13, No. 1 · pp. 1201-1201

Essential amino acids as diagnostic biomarkers of hepatocellular carcinoma based on metabolic analysis Research Paper

Yuji Morine, Tohru Utsunomiya, Hisami Yamanaka-Okumura, Yu Saito, Shinichiro Yamada, Tetsuya Ikemoto, Satoru Imura, Shohei Kinoshita, Akiyoshi Hirayama, Yasuhito Tanaka, Mitsuo Shimada

Published Oct 27, 2022 · Vol. 13, No. 1 · pp. 1286-1298

Keywords: metabolomics, essential amino acid, hepatocellular carcinoma, diagnostic biomarker

MK256 is a novel CDK8 inhibitor with potent antitumor activity in AML through downregulation of the STAT pathway Research Paper

Jen-Chieh Lee, Shu Liu, Yucheng Wang, You Liang, David M. Jablons

Published Oct 26, 2022 · Vol. 13, No. 1 · pp. 1217-1236

Keywords: AML, CDK8, kinase inhibitor, STAT pathway, xenograft

Tumor hyaluronan as a novel biomarker in non-small cell lung cancer: A retrospective study Research Paper

Jun Gong, Michelle Guan, Haesoo Kim, Natalie Moshayedi, Sejal Mehta, Galen Cook-Wiens, Brent K. Larson, Jenny Zhou, Rishi Patel, Isaac Lapite, Veronica R. Placencio-Hickok, Richard Tuli, Ronald B. Natale, Andrew E. Hendifar

Published Oct 25, 2022 · Vol. 13, No. 1 · pp. 1202-1214

Keywords: hyaluronan, hyaluronic acid, biomarker, prognostic, predictive

Myeloid-derived suppressor cells: Cancer, autoimmune diseases, and more Review

Masahiko Shibata, Kotaro Nanno, Daigo Yoshimori, Takahiro Nakajima, Makoto Takada, Takashi Yazawa, Kousaku Mimura, Norio Inoue, Takafumi Watanabe, Kazunoshin Tachibana, Satoshi Muto, Tomoyuki Momma, Yoshiyuki Suzuki, Koji Kono, Shungo Endo, Seiichi Takenoshita

Published Oct 25, 2022 · Vol. 13, No. 1 · pp. 1273-1285

Keywords: MDSC, immunosuppression, Treg, TAM, cancer

Predictive molecular biomarkers for determining neoadjuvant chemosensitivity in muscle invasive bladder cancer Research Paper

Neal Murphy, Andrew J. Shih, Paras Shah, Oksana Yaskiv, Houman Khalili, Anthony Liew, Annette T. Lee, Xin-Hua Zhu

Published Oct 20, 2022 · Vol. 13, No. 1 · pp. 1188-1200

Keywords: muscle invasive bladder cancer, neoadjuvant chemotherapy, gene expression, molecular subtyping, canonical correlation analysis

The serine protease matriptase inhibits migration and proliferation in multiple myeloma cells Research Paper

Ida Steiro, Esten N. Vandsemb, Samah Elsaadi, Kristine Misund, Anne-Marit Sponaas, Magne Børset, Pegah Abdollahi, Tobias S. Slørdahl

Published Oct 15, 2022 · Vol. 13, No. 1 · pp. 1175-1186

Keywords: matriptase, multiple myeloma, tumor suppressor, migration, Src

Nectin-4 is widely expressed in head and neck squamous cell carcinoma Research Paper

Christine Sanders, Jan-Frederic Lau, Dimo Dietrich, Sebastian Strieth, Peter Brossart, Glen Kristiansen

Published Oct 14, 2022 · Vol. 13, No. 1 · pp. 1166-1173

Keywords: Nectin-4, enfortumab-vedotin, HNSCC, p16

Addendum: BCMab1-Ra, a novel immunotoxin that BCMab1 antibody coupled to Ricin A chain, can eliminate bladder tumor Addendum

Chong Li, Ruping Yan, Zhao Yang, Haifeng Wang, Ruiyun Zhang, Haige Chen, Jiansong Wang

Published Oct 11, 2022

Therapeutic efficacy of the humanized JAA-F11 anti-Thomsen-Friedenreich antibody constructs H2aL2a and H3L3 in human breast and lung cancer xenograft models Research Paper

Diala Ghazal, Fatma Zalzala, John C. Fisk, Swetha Tati, Loukia G. Karacosta, Susan Morey, James R. Olson, Sally Quataert, Grace K. Dy, Kate Rittenhouse-Olson

Published Oct 7, 2022 · Vol. 13, No. 1 · pp. 1155-1164

Keywords: hJAA-F11, TF-Ag, Thomsen-Friedenreich antigen, tumor immunotherapy, translational oncology

Platelet-derived growth factor (PDGF) cross-signaling via non-corresponding receptors indicates bypassed signaling in colorectal cancer Research Paper

Romana Moench, Martin Gasser, Karol Nawalaniec, Tanja Grimmig, Amrendra K. Ajay, Larissa Camila Ribeiro de Souza, Minghua Cao, Yueming Luo, Petra Hoegger, Carmen M. Ribas, Jurandir M. Ribas-Filho, Osvaldo Malafaia, Reinhard Lissner, Li-Li Hsiao, Ana Maria Waaga-Gasser

Published Oct 6, 2022 · Vol. 13, No. 1 · pp. 1140-1152

Keywords: PDGF, VEGFR, EGFR, bypassed signaling, colorectal cancer

In vitro chemotherapy-associated muscle toxicity is attenuated with nutritional support, while treatment efficacy is retained Research Paper

Liza A. Wijler, Francina J. Dijk, Hanil Quirindongo, Danielle A.E. Raats, Bram Dorresteijn, Matthew J.W. Furber, Anne M. May, Onno Kranenburg, Miriam van Dijk

Published Sep 27, 2022 · Vol. 13, No. 1 · pp. 1094-1108

Keywords: C2C12 myotubes, chemotherapy, chemotherapy-associated toxicity, colorectal cancer, nutrients, tumor (organoid) cells

HDAC inhibitors suppress protein poly(ADP-ribosyl)ation and DNA repair protein levels and phosphorylation status in hematologic cancer cells: implications for their use in combination with PARP inhibitors and chemotherapeutic drugs Research Paper

Benigno C. Valdez, Yago Nieto, Bin Yuan, David Murray, Borje S. Andersson

Published Sep 24, 2022 · Vol. 13, No. 1 · pp. 1122-1135

Keywords: poly(ADP-ribosyl)ation, HDAC inhibitors, PARP inhibitors, chemotherapy, hematologic malignancy

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Calcium signaling induced by 15-deoxy-prostamide-J₂ promotes cell death by activating PERK, IP3R, and the mitochondrial permeability transition pore Research Paper

Anti-tumor effect of antibody drug conjugate ASP1235 targeting Fms-like tyrosine kinase 3 with venetoclax plus azacitidine in an acute myeloid leukemia xenograft mouse model Research Paper

Resistance of MMTV-NeuT/ATTAC mice to anti-PD-1 immune checkpoint therapy is associated with macrophage infiltration and Wnt pathway expression Research Paper

Addendum: Real-world survival analysis by tumor mutational burden in non-small cell lung cancer: a multisite U.S. study Addendum

Addendum: Hyperprogression and impact of tumor growth kinetics after PD1/PDL1 inhibition in head and neck squamous cell carcinoma Addendum

Mutation analysis performed on tumor biopsies from patients with newly-diagnosed germinal center aggressive B cell lymphomas Research Paper

Treasures from trash in cancer research Research Perspective

Retraction: SAMMSON drives the self-renewal of liver tumor initiating cells through EZH2-dependent Wnt/β-catenin activation Retraction

Essential amino acids as diagnostic biomarkers of hepatocellular carcinoma based on metabolic analysis Research Paper

MK256 is a novel CDK8 inhibitor with potent antitumor activity in AML through downregulation of the STAT pathway Research Paper

Tumor hyaluronan as a novel biomarker in non-small cell lung cancer: A retrospective study Research Paper

Myeloid-derived suppressor cells: Cancer, autoimmune diseases, and more Review

Predictive molecular biomarkers for determining neoadjuvant chemosensitivity in muscle invasive bladder cancer Research Paper

The serine protease matriptase inhibits migration and proliferation in multiple myeloma cells Research Paper

Nectin-4 is widely expressed in head and neck squamous cell carcinoma Research Paper

Addendum: BCMab1-Ra, a novel immunotoxin that BCMab1 antibody coupled to Ricin A chain, can eliminate bladder tumor Addendum

Therapeutic efficacy of the humanized JAA-F11 anti-Thomsen-Friedenreich antibody constructs H2aL2a and H3L3 in human breast and lung cancer xenograft models Research Paper

Platelet-derived growth factor (PDGF) cross-signaling via non-corresponding receptors indicates bypassed signaling in colorectal cancer Research Paper

In vitro chemotherapy-associated muscle toxicity is attenuated with nutritional support, while treatment efficacy is retained Research Paper

HDAC inhibitors suppress protein poly(ADP-ribosyl)ation and DNA repair protein levels and phosphorylation status in hematologic cancer cells: implications for their use in combination with PARP inhibitors and chemotherapeutic drugs Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

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Calcium signaling induced by 15-deoxy-prostamide-J2 promotes cell death by activating PERK, IP3R, and the mitochondrial permeability transition pore Research Paper

Anti-tumor effect of antibody drug conjugate ASP1235 targeting Fms-like tyrosine kinase 3 with venetoclax plus azacitidine in an acute myeloid leukemia xenograft mouse model Research Paper

Resistance of MMTV-NeuT/ATTAC mice to anti-PD-1 immune checkpoint therapy is associated with macrophage infiltration and Wnt pathway expression Research Paper

Addendum: Real-world survival analysis by tumor mutational burden in non-small cell lung cancer: a multisite U.S. study Addendum

Addendum: Hyperprogression and impact of tumor growth kinetics after PD1/PDL1 inhibition in head and neck squamous cell carcinoma Addendum

Mutation analysis performed on tumor biopsies from patients with newly-diagnosed germinal center aggressive B cell lymphomas Research Paper

Treasures from trash in cancer research Research Perspective

Retraction: SAMMSON drives the self-renewal of liver tumor initiating cells through EZH2-dependent Wnt/β-catenin activation Retraction

Essential amino acids as diagnostic biomarkers of hepatocellular carcinoma based on metabolic analysis Research Paper

MK256 is a novel CDK8 inhibitor with potent antitumor activity in AML through downregulation of the STAT pathway Research Paper

Tumor hyaluronan as a novel biomarker in non-small cell lung cancer: A retrospective study Research Paper

Myeloid-derived suppressor cells: Cancer, autoimmune diseases, and more Review

Predictive molecular biomarkers for determining neoadjuvant chemosensitivity in muscle invasive bladder cancer Research Paper

The serine protease matriptase inhibits migration and proliferation in multiple myeloma cells Research Paper

Nectin-4 is widely expressed in head and neck squamous cell carcinoma Research Paper

Addendum: BCMab1-Ra, a novel immunotoxin that BCMab1 antibody coupled to Ricin A chain, can eliminate bladder tumor Addendum

Therapeutic efficacy of the humanized JAA-F11 anti-Thomsen-Friedenreich antibody constructs H2aL2a and H3L3 in human breast and lung cancer xenograft models Research Paper

Platelet-derived growth factor (PDGF) cross-signaling via non-corresponding receptors indicates bypassed signaling in colorectal cancer Research Paper

In vitro chemotherapy-associated muscle toxicity is attenuated with nutritional support, while treatment efficacy is retained Research Paper

HDAC inhibitors suppress protein poly(ADP-ribosyl)ation and DNA repair protein levels and phosphorylation status in hematologic cancer cells: implications for their use in combination with PARP inhibitors and chemotherapeutic drugs Research Paper

Calcium signaling induced by 15-deoxy-prostamide-J₂ promotes cell death by activating PERK, IP3R, and the mitochondrial permeability transition pore Research Paper