The Oncosearch | Oncotarget

In vivo treatment with epigenetic modulating agents induces transcriptional alterations associated with prognosis and immunomodulation in multiple myeloma Research Paper

Ken Maes, Eva De Smedt, Alboukadel Kassambara, Dirk Hose, Anja Seckinger, Els Van Valckenborgh, Eline Menu, Bernard Klein, Karin Vanderkerken, JÃ©rÃ´me Moreaux, Elke De Bruyne

Published Dec 26, 2014 · Vol. 6, No. 5 · pp. 3319-3334

miR-638 promotes melanoma metastasis and protects melanoma cells from apoptosis and autophagy Research Paper

Animesh Bhattacharya, Ulf Schmitz, Yvonne Raatz, Madeleine SchÃ¶nherr, Tina Kottek, Marianne Schauer, Sandra Franz, Anja Saalbach, Ulf Anderegg, Olaf Wolkenhauer, Dirk Schadendorf, Jan C. Simon, Thomas Magin, Julio Vera, Manfred Kunz

Published Dec 26, 2014 · Vol. 6, No. 5 · pp. 2966-2980

Preclinical antitumor activity of ST7612AA1: a new oral thiol-based histone deacetylase (HDAC) inhibitor Research Paper

Loredana Vesci, Elena Bernasconi, Ferdinando Maria Milazzo, Rita De Santis, Eugenio Gaudio, Ivo Kwee, Andrea Rinaldi, Silvia Pace, Valeria Carollo, Giuseppe Giannini, Francesco Bertoni

Published Dec 25, 2014 · Vol. 6, No. 8 · pp. 5735-5748

Mitochondrial p32 is upregulated in Myc expressing brain cancers and mediates glutamine addiction Research Paper

Valentina Fogal, Ivan Babic, Ying Chao, Sandra Pastorino, Rajesh Mukthavaram, Pengfei Jiang, Yoon-Jae Cho, Sandeep C. Pingle, John R. Crawford, David E. Piccioni, Santosh Kesari

Published Dec 22, 2014 · Vol. 6, No. 2 · pp. 1157-1170

Keywords: mitochondrial p32, c-Myc, glutamine addiction, brain cancer

Transcriptional regulation of Sox2 by the retinoblastoma family of pocket proteins Research Paper

JÃ©ssica M. Vilas, Alba FerreirÃ³s, Carmen Carneiro, Lluis Morey, Sabela Da Silva-Ãlvarez, TÃ¢nia Fernandes, MarÃa Abad, Luciano Di Croce, TomÃ¡s GarcÃa-Caballero, Manuel Serrano, Carmen Rivas, Anxo Vidal, Manuel Collado

Published Dec 18, 2014 · Vol. 6, No. 5 · pp. 2992-3002

Hypoxia-inducible factor 1 mediates TAZ expression and nuclear localization to induce the breast cancer stem cell phenotype Priority Research Paper

Lisha Xiang, Daniele M. Gilkes, Hongxia Hu, Naoharu Takano, Weibo Luo, Haiquan Lu, John W. Bullen, Debangshu Samanta, Houjie Liang, Gregg L. Semenza

Published Dec 18, 2014 · Vol. 5, No. 24 · pp. 12509-12527

A role for BMP-induced homeobox gene MIXL1 in acute myelogenous leukemia and identification of type I BMP receptor as a potential target for therapy Research Paper

Aaron Raymond, Bin Liu, Hong Liang, Ciamaio Wei, Michele Guindani, Yue Lu, Shoudan Liang, Lisa S. St. John, Jeff Molldrem, Lalitha Nagarajan

Published Dec 17, 2014 · Vol. 5, No. 24 · pp. 12675-12693

The T-box transcription factor, TBX3, is a key substrate of AKT3 in melanomagenesis Research Paper

Jade Peres, Shaheen Mowla, Sharon Prince

Published Dec 16, 2014 · Vol. 6, No. 3 · pp. 1821-1833

Keywords: TBX3, AKT3, melanoma, E-cadherin, T-box factors.

PARP targeting counteracts gliomagenesis through induction of mitotic catastrophe and aggravation of deficiency in homologous recombination in PTEN-mutant glioma Research Paper

Jara Majuelos-Melguizo, MarÃa Isabel RodrÃguez, Laura LÃ³pez-JimÃ©nez, Jose M. RodrÃguez-Vargas, Juan M. MartÃ MartÃn-Consuegra, Santiago Serrano-SÃ¡enz, Julie Gavard, J. Mariano Ruiz de AlmodÃ³var, F. Javier Oliver

Published Dec 11, 2014 · Vol. 6, No. 7 · pp. 4790-4803

Active secretion of CXCL10 and CCL5 from colorectal cancer microenvironments associates with GranzymeB+ CD8+ T-cell infiltration Research Paper

Timothy J. Zumwalt, Mildred Arnold, Ajay Goel, C. Richard Boland

Published Dec 11, 2014 · Vol. 6, No. 5 · pp. 2981-2991

The anti-leukemic activity of sodium dichloroacetate in p53^mutated/null cells is mediated by a p53-independent ILF3/p21 pathway Research Paper

Chiara Agnoletto, Laura Brunelli, Elisabetta Melloni, Roberta Pastorelli, Fabio Casciano, Erika Rimondi, Gian Matteo Rigolin, Antonio Cuneo, Paola Secchiero, Giorgio Zauli

Published Dec 10, 2014 · Vol. 6, No. 4 · pp. 2385-2396

MicroRNAs in B-cells: from normal differentiation to treatment of malignancies Review

Sara Correia Marques, Maria Bach Laursen, Julie StÃ¸ve BÃ¸dker, Malene Krag Kjeldsen, Steffen Falgreen, Alexander Schmitz, Martin BÃ¸gsted, Hans Erik Johnsen, Karen Dybkaer

Published Dec 10, 2014 · Vol. 6, No. 1 · pp. 7-25

TGF-Î²1 induces epigenetic silence of TIP30 to promote tumor metastasis in esophageal carcinoma Research Paper

Fangfang Bu, Xing Liu, Jingjing Li, Shukun Chen, Xin Tong, Chunsheng Ma, Hui Mao, Fei Pan, Xiaoyan Li, Bo Chen, Liyan Xu, Enmin Li, Geng Kou, Jun Han, Shangjing Guo, Jian Zhao, Yajun Guo

Published Dec 3, 2014 · Vol. 6, No. 4 · pp. 2120-2133

Connexin32 regulates hepatoma cell metastasis and proliferation via the p53 and Akt pathways Research Paper

Bixing Zhao, Wenxiu Zhao, Yu Wang, Yaping Xu, Jianfeng Xu, Kai Tang, Sheng Zhang, Zhenyu Yin, Qiao Wu, Xiaomin Wang

Published Nov 27, 2014 · Vol. 6, No. 12 · pp. 10116-10133

ZHX2 enhances the cytotoxicity of chemotherapeutic drugs in liver tumor cells by repressing MDR1 via interfering with NF-YA Research Paper

Hongxin Ma, Xuetian Yue, Lifen Gao, Xiaohong Liang, Wenjiang Yan, Zhenyu Zhang, Haixia Shan, Hualin Zhang, Brett T. Spear, Chunhong Ma

Published Nov 26, 2014 · Vol. 6, No. 2 · pp. 1049-1063

FGF8 promotes colorectal cancer growth and metastasis by activating YAP1 Research Paper

Rui Liu, Shan Huang, Yunlong Lei, Tao Zhang, Kui Wang, Bo Liu, Edouard C. Nice, Rong Xiang, Ke Xie, Jingyi Li, Canhua Huang

Published Nov 26, 2014 · Vol. 6, No. 2 · pp. 935-952

HDAC2 deregulation in tumorigenesis is causally connected to repression of immune modulation and defense escape Research Paper

Mariarosaria Conte, Carmela Dellâ€™Aversana, Rosaria Benedetti, Francesca Petraglia, Annamaria Carissimo, Valeria Belsito Petrizzi, Alfonso Maria Dâ€™Arco, Ciro Abbondanza, Angela Nebbioso, Lucia Altucci

Published Nov 25, 2014 · Vol. 6, No. 2 · pp. 886-901

DNA methylome analysis identifies epigenetic silencing of FHIT as a determining factor for radiosensitivity in oral cancer: an outcome-predicting and treatment-implicating study Research Paper

Hon-Yi Lin, Shih-Kai Hung, Moon-Sing Lee, Wen-Yen Chiou, Tze-Ta Huang, Chih-En Tseng, Liang-Yu Shih, Ru-Inn Lin, Jora M.J. Lin, Yi-Hui Lai, Chia-Bin Chang, Feng-Chun Hsu, Liang-Cheng Chen, Shiang-Jiun Tsai, Yu-Chieh Su, Szu-Chi Li, Hung-Chih Lai, Wen-Lin Hsu, Dai-Wei Liu, Chien-Kuo Tai, Shu-Fen Wu, Michael W.Y. Chan

Published Nov 25, 2014 · Vol. 6, No. 2 · pp. 915-934

Transcriptomic profiling of taxol-resistant ovarian cancer cells identifies FKBP5 and the androgen receptor as critical markers of chemotherapeutic response Research Paper

Nian-Kang Sun, Shang-Lang Huang, Pu-Yuan Chang, Hsing-Pang Lu, Chuck C.-K. Chao

Published Nov 17, 2014 · Vol. 5, No. 23 · pp. 11939-11956

Targeting hypoxia-inducible factor-1Î± (HIF-1Î±) in combination with antiangiogenic therapy: A phase I trial of bortezomib plus bevacizumab Clinical Research Papers

Gerald S. Falchook, Jennifer J. Wheler, Aung Naing, Edward F. Jackson, Filip Janku, David Hong, Chaan S. Ng, Nizar M. Tannir, Kristie N. Lawhorn, Mei Huang, Laura S. Angelo, Deeksha Vishwamitra, Kenneth Hess, Adrienne N. Howard, Kristin L. Parkhurst, Hesham M. Amin, Razelle Kurzrock

Published Nov 8, 2014 · Vol. 5, No. 21 · pp. 10280-10292

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In vivo treatment with epigenetic modulating agents induces transcriptional alterations associated with prognosis and immunomodulation in multiple myeloma Research Paper

miR-638 promotes melanoma metastasis and protects melanoma cells from apoptosis and autophagy Research Paper

Preclinical antitumor activity of ST7612AA1: a new oral thiol-based histone deacetylase (HDAC) inhibitor Research Paper

Mitochondrial p32 is upregulated in Myc expressing brain cancers and mediates glutamine addiction Research Paper

Transcriptional regulation of Sox2 by the retinoblastoma family of pocket proteins Research Paper

Hypoxia-inducible factor 1 mediates TAZ expression and nuclear localization to induce the breast cancer stem cell phenotype Priority Research Paper

A role for BMP-induced homeobox gene MIXL1 in acute myelogenous leukemia and identification of type I BMP receptor as a potential target for therapy Research Paper

The T-box transcription factor, TBX3, is a key substrate of AKT3 in melanomagenesis Research Paper

PARP targeting counteracts gliomagenesis through induction of mitotic catastrophe and aggravation of deficiency in homologous recombination in PTEN-mutant glioma Research Paper

Active secretion of CXCL10 and CCL5 from colorectal cancer microenvironments associates with GranzymeB+ CD8+ T-cell infiltration Research Paper

The anti-leukemic activity of sodium dichloroacetate in p53^mutated/null cells is mediated by a p53-independent ILF3/p21 pathway Research Paper

MicroRNAs in B-cells: from normal differentiation to treatment of malignancies Review

TGF-Î²1 induces epigenetic silence of TIP30 to promote tumor metastasis in esophageal carcinoma Research Paper

Connexin32 regulates hepatoma cell metastasis and proliferation via the p53 and Akt pathways Research Paper

ZHX2 enhances the cytotoxicity of chemotherapeutic drugs in liver tumor cells by repressing MDR1 via interfering with NF-YA Research Paper

FGF8 promotes colorectal cancer growth and metastasis by activating YAP1 Research Paper

HDAC2 deregulation in tumorigenesis is causally connected to repression of immune modulation and defense escape Research Paper

DNA methylome analysis identifies epigenetic silencing of FHIT as a determining factor for radiosensitivity in oral cancer: an outcome-predicting and treatment-implicating study Research Paper

Transcriptomic profiling of taxol-resistant ovarian cancer cells identifies FKBP5 and the androgen receptor as critical markers of chemotherapeutic response Research Paper

Targeting hypoxia-inducible factor-1Î± (HIF-1Î±) in combination with antiangiogenic therapy: A phase I trial of bortezomib plus bevacizumab Clinical Research Papers

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

In vivo treatment with epigenetic modulating agents induces transcriptional alterations associated with prognosis and immunomodulation in multiple myeloma Research Paper

miR-638 promotes melanoma metastasis and protects melanoma cells from apoptosis and autophagy Research Paper

Preclinical antitumor activity of ST7612AA1: a new oral thiol-based histone deacetylase (HDAC) inhibitor Research Paper

Mitochondrial p32 is upregulated in Myc expressing brain cancers and mediates glutamine addiction Research Paper

Transcriptional regulation of Sox2 by the retinoblastoma family of pocket proteins Research Paper

Hypoxia-inducible factor 1 mediates TAZ expression and nuclear localization to induce the breast cancer stem cell phenotype Priority Research Paper

A role for BMP-induced homeobox gene MIXL1 in acute myelogenous leukemia and identification of type I BMP receptor as a potential target for therapy Research Paper

The T-box transcription factor, TBX3, is a key substrate of AKT3 in melanomagenesis Research Paper

PARP targeting counteracts gliomagenesis through induction of mitotic catastrophe and aggravation of deficiency in homologous recombination in PTEN-mutant glioma Research Paper

Active secretion of CXCL10 and CCL5 from colorectal cancer microenvironments associates with GranzymeB+ CD8+ T-cell infiltration Research Paper

The anti-leukemic activity of sodium dichloroacetate in p53mutated/null cells is mediated by a p53-independent ILF3/p21 pathway Research Paper

MicroRNAs in B-cells: from normal differentiation to treatment of malignancies Review

TGF-Î²1 induces epigenetic silence of TIP30 to promote tumor metastasis in esophageal carcinoma Research Paper

Connexin32 regulates hepatoma cell metastasis and proliferation via the p53 and Akt pathways Research Paper

ZHX2 enhances the cytotoxicity of chemotherapeutic drugs in liver tumor cells by repressing MDR1 via interfering with NF-YA Research Paper

FGF8 promotes colorectal cancer growth and metastasis by activating YAP1 Research Paper

HDAC2 deregulation in tumorigenesis is causally connected to repression of immune modulation and defense escape Research Paper

DNA methylome analysis identifies epigenetic silencing of FHIT as a determining factor for radiosensitivity in oral cancer: an outcome-predicting and treatment-implicating study Research Paper

Transcriptomic profiling of taxol-resistant ovarian cancer cells identifies FKBP5 and the androgen receptor as critical markers of chemotherapeutic response Research Paper

Targeting hypoxia-inducible factor-1Î± (HIF-1Î±) in combination with antiangiogenic therapy: A phase I trial of bortezomib plus bevacizumab Clinical Research Papers

The anti-leukemic activity of sodium dichloroacetate in p53^mutated/null cells is mediated by a p53-independent ILF3/p21 pathway Research Paper