The Oncosearch | Oncotarget

Computational drugs repositioning identifies inhibitors of oncogenic PI3K/AKT/P70S6K-dependent pathways among FDA-approved compounds Priority Research Paper

Diego Carrella, Isabella Manni, Barbara Tumaini, Rosanna Dattilo, Federica Papaccio, Margherita Mutarelli, Francesco Sirci, Carla A. Amoreo, Marcella Mottolese, Manuela Iezzi, Laura Ciolli, Valentina Aria, Roberta Bosotti, Antonella Isacchi, Fabrizio Loreni, Alberto Bardelli, Vittorio E. Avvedimento, Diego di Bernardo, Luca Cardone

Published Aug 16, 2016 · Vol. 7, No. 37 · pp. 58743-58758

The putative tumor suppressor gene EphA7 is a novel BMI-1 target Research Paper

GaÃ«lle Prost, Sebastian Braun, Falk Hertwig, Marcus Winkler, Lucas Jagemann, Sara Nolbrant, Isabelle V. Leefa, Nils Offen, Kenichi Miharada, Stefan Lang, Isabella Artner, Ulrike A. Nuber

Published Aug 13, 2016 · Vol. 7, No. 36 · pp. 58203-58217

Impacts of the mTOR gene polymorphisms rs2536 and rs2295080 on breast cancer risk in the Chinese population Research Paper

Yang Zhao, Yan Diao, XiJing Wang, Shuai Lin, Meng Wang, HuaFeng Kang, PengTao Yang, Cong Dai, XingHan Liu, Kang Liu, ShanLi Li, YuYao Zhu, ZhiJun Dai

Published Aug 12, 2016 · Vol. 7, No. 36 · pp. 58174-58180

PRIMA-1 targets the vulnerability of multiple myeloma of deregulated protein homeostasis through the perturbation of ER stress via p73 demethylation Research Paper

Phaik Ju Teoh, Chonglei Bi, Chirackal Sintosebastian, Liang Seah Tay, Rafael Fonseca, Wee Joo Chng

Published Aug 12, 2016 · Vol. 7, No. 38 · pp. 61806-61819

PPARÎ³ agonists promote differentiation of cancer stem cells by restraining YAP transcriptional activity Research Paper

Upal Basu-Roy, Eugenia Han, Kirk Rattanakorn, Abhilash Gadi, Narendra Verma, Giulia Maurizi, Preethi H. Gunaratne, Cristian Coarfa, Oran D. Kennedy, Michael J. Garabedian, Claudio Basilico, Alka Mansukhani

Published Aug 12, 2016 · Vol. 7, No. 38 · pp. 60954-60970

Wnt signalling is a bi-directional vulnerability of cancer cells Research Paper

David J. Duffy, Aleksandar Krstic, Thomas Schwarzl, Melinda Halasz, Kristiina Iljin, Dirk Fey, Bridget Haley, Jenny Whilde, Saija Haapa-Paananen, Vidal Fey, Matthias Fischer, Frank Westermann, Kai-Oliver Henrich, Steffen Bannert, Desmond G. Higgins, Walter Kolch

Published Aug 11, 2016 · Vol. 7, No. 37 · pp. 60310-60331

Ligand dependent restoration of human TLR3 signaling and death in p53 mutant cells Research Paper

Daniel Menendez, Julie M. Lowe, Joyce Snipe, Michael A. Resnick

Published Aug 11, 2016 · Vol. 7, No. 38 · pp. 61630-61642

A steroid like phytochemical Antcin M is an anti-aging reagent that eliminates hyperglycemia-accelerated premature senescence in dermal fibroblasts by direct activation of Nrf2 and SIRT-1 Research Paper

Kumar K.J. Senthil, Vani M. Gokila, Jeng-Leun Mau, Chin-Chung Lin, Fang-Hua Chu, Chia-Cheng Wei, Vivian Hsiu-Chuan Liao, Sheng-Yang Wang

Published Aug 11, 2016 · Vol. 7, No. 39 · pp. 62836-62861

YM155 sensitizes TRAIL-induced apoptosis through cathepsin S-dependent down-regulation of Mcl-1 and NF-κB-mediated down-regulation of c-FLIP expression in human renal carcinoma Caki cells Research Paper

Seon Min Woo, Kyoung-jin Min, Bo Ram Seo, Taeg Kyu Kwon

Published Aug 9, 2016 · Vol. 7, No. 38 · pp. 61520-61532

Stromal remodeling by the BET bromodomain inhibitor JQ1 suppresses the progression of human pancreatic cancer Research Paper

Keisuke Yamamoto, Keisuke Tateishi, Yotaro Kudo, Mayumi Hoshikawa, Mariko Tanaka, Takuma Nakatsuka, Hiroaki Fujiwara, Koji Miyabayashi, Ryota Takahashi, Yasuo Tanaka, Hideaki Ijichi, Yousuke Nakai, Hiroyuki Isayama, Yasuyuki Morishita, Taku Aoki, Yoshihiro Sakamoto, Kiyoshi Hasegawa, Norihiro Kokudo, Masashi Fukayama, Kazuhiko Koike

Published Aug 9, 2016 · Vol. 7, No. 38 · pp. 61469-61484

miR-31 targets ARID1A and enhances the oncogenicity and stemness of head and neck squamous cell carcinoma Research Paper

Wen-Cheng Lu, Chung-Ji Liu, Hsi-Feng Tu, Yu-Tung Chung, Cheng-Chieh Yang, Shou-Yen Kao, Kuo-Wei Chang, Shu-Chun Lin

Published Aug 9, 2016 · Vol. 7, No. 35 · pp. 57254-57267

Glypican-3 induces a mesenchymal to epithelial transition in human breast cancer cells Research Paper

Lilian Fedra Castillo, RocÃo TascÃ³n, MarÃa Amparo Lago Huvelle, Gisela Novack, MarÃa Candelaria Llorens, Ancely Ferreira dos Santos, Jorge Shortrede, Ana MarÃa Cabanillas, Elisa Bal de Kier JoffÃ©, Leticia Labriola, MarÃa Giselle Peters

Published Aug 6, 2016 · Vol. 7, No. 37 · pp. 60133-60154

C23 promotes tumorigenesis via suppressing p53 activity Research Paper

Qun Li, Yan Zhu, Lili Hou, Juan Wang, Guilin Hu, Xing Fang, Yamin Hu, Tingting Tao, Xin Wei, Haitao Tang, Baojun Huang, Wanglai Hu

Published Aug 5, 2016 · Vol. 7, No. 36 · pp. 58274-58285

Regulation of cellular quiescence by YAP/TAZ and Cyclin E1 in colon cancer cells: Implication in chemoresistance and cancer relapse Research Paper

Matthieu Corvaisier, Marjolaine Bauzone, FranÃ§ois Corfiotti, Florence Renaud, Mehdi El Amrani, Didier MontÃ©, StÃ©phanie Truant, Emmanuelle Leteurtre, Pierre Formstecher, Isabelle Van Seuningen, Christian Gespach, Guillemette Huet

Published Aug 4, 2016 · Vol. 7, No. 35 · pp. 56699-56712

Nucleophosmin/B23 is a negative regulator of estrogen receptor α expression via AP2γ in endometrial cancer cells Research Paper

Chiao-Yun Lin, Angel Chao, Tzu-Hao Wang, Li-Yu Lee, Lan-Yan Yang, Chia-Lung Tsai, Hsin-Shih Wang, Chyong-Huey Lai

Published Aug 4, 2016 · Vol. 7, No. 37 · pp. 60038-60052

FOXM1 confers resistance to gefitinib in lung adenocarcinoma via a MET/AKT-dependent positive feedback loop Research Paper

Yu Wang, Weiwei Zhang, Li Wen, Huiling Yang, Mingling Wen, Yuyu Yun, Lisheng Zhao, Xiaofei Zhu, Li Tian, Erping Luo, Yu Li, Wenchao Liu, Ning Wen

Published Aug 3, 2016 · Vol. 7, No. 37 · pp. 59245-59259

Expression of the p66Shc protein adaptor is regulated by the activator of transcription STAT4 in normal and chronic lymphocytic leukemia B cells Research Paper

Francesca Cattaneo, Laura Patrussi, Nagaja Capitani, Federica Frezzato, Mario Milco Dâ€™Elios, Livio Trentin, Gianpietro Semenzato, Cosima T. Baldari

Published Aug 1, 2016 · Vol. 7, No. 35 · pp. 57086-57098

Intra-tumoral delivery of functional ID4 protein via PCL/maltodextrin nano-particle inhibits prostate cancer growth Research Paper

Maxwell Korang-Yeboah, Divya Patel, Derrick Morton, Pankaj Sharma, Yamini Gorantla, Jugal Joshi, Perri Nagappan, Ravi Pallaniappan, Jaideep Chaudhary

Published Jul 30, 2016 · Vol. 7, No. 42 · pp. 68072-68085

IGF-II induced by hepatitis B virus X protein regulates EMT via SUMO mediated loss of E-cadherin in mice Research Paper

Hye-Lin Ha, Taeho Kwon, In Seon Bak, Raymond L. Erikson, Bo Yeon Kim, Dae-Yeul Yu

Published Jul 29, 2016 · Vol. 7, No. 35 · pp. 56944-56957

Oncostatin M suppresses metastasis of lung adenocarcinoma by inhibiting SLUG expression through coordination of STATs and PIASs signalings Research Paper

Chih-Ming Pan, Mong-Lien Wang, Shih-Hwa Chiou, Hsiao-Yun Chen, Cheng-Wen Wu

Published Jul 29, 2016 · Vol. 7, No. 37 · pp. 60395-60406

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Computational drugs repositioning identifies inhibitors of oncogenic PI3K/AKT/P70S6K-dependent pathways among FDA-approved compounds Priority Research Paper

The putative tumor suppressor gene EphA7 is a novel BMI-1 target Research Paper

Impacts of the mTOR gene polymorphisms rs2536 and rs2295080 on breast cancer risk in the Chinese population Research Paper

PRIMA-1 targets the vulnerability of multiple myeloma of deregulated protein homeostasis through the perturbation of ER stress via p73 demethylation Research Paper

PPARÎ³ agonists promote differentiation of cancer stem cells by restraining YAP transcriptional activity Research Paper

Wnt signalling is a bi-directional vulnerability of cancer cells Research Paper

Ligand dependent restoration of human TLR3 signaling and death in p53 mutant cells Research Paper

A steroid like phytochemical Antcin M is an anti-aging reagent that eliminates hyperglycemia-accelerated premature senescence in dermal fibroblasts by direct activation of Nrf2 and SIRT-1 Research Paper

YM155 sensitizes TRAIL-induced apoptosis through cathepsin S-dependent down-regulation of Mcl-1 and NF-κB-mediated down-regulation of c-FLIP expression in human renal carcinoma Caki cells Research Paper

Stromal remodeling by the BET bromodomain inhibitor JQ1 suppresses the progression of human pancreatic cancer Research Paper

miR-31 targets ARID1A and enhances the oncogenicity and stemness of head and neck squamous cell carcinoma Research Paper

Glypican-3 induces a mesenchymal to epithelial transition in human breast cancer cells Research Paper

C23 promotes tumorigenesis via suppressing p53 activity Research Paper

Regulation of cellular quiescence by YAP/TAZ and Cyclin E1 in colon cancer cells: Implication in chemoresistance and cancer relapse Research Paper

Nucleophosmin/B23 is a negative regulator of estrogen receptor α expression via AP2γ in endometrial cancer cells Research Paper

FOXM1 confers resistance to gefitinib in lung adenocarcinoma via a MET/AKT-dependent positive feedback loop Research Paper

Expression of the p66Shc protein adaptor is regulated by the activator of transcription STAT4 in normal and chronic lymphocytic leukemia B cells Research Paper

Intra-tumoral delivery of functional ID4 protein via PCL/maltodextrin nano-particle inhibits prostate cancer growth Research Paper

IGF-II induced by hepatitis B virus X protein regulates EMT via SUMO mediated loss of E-cadherin in mice Research Paper

Oncostatin M suppresses metastasis of lung adenocarcinoma by inhibiting SLUG expression through coordination of STATs and PIASs signalings Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Computational drugs repositioning identifies inhibitors of oncogenic PI3K/AKT/P70S6K-dependent pathways among FDA-approved compounds Priority Research Paper

The putative tumor suppressor gene EphA7 is a novel BMI-1 target Research Paper

Impacts of the mTOR gene polymorphisms rs2536 and rs2295080 on breast cancer risk in the Chinese population Research Paper

PRIMA-1 targets the vulnerability of multiple myeloma of deregulated protein homeostasis through the perturbation of ER stress via p73 demethylation Research Paper

PPARÎ³ agonists promote differentiation of cancer stem cells by restraining YAP transcriptional activity Research Paper

Wnt signalling is a bi-directional vulnerability of cancer cells Research Paper

Ligand dependent restoration of human TLR3 signaling and death in p53 mutant cells Research Paper

A steroid like phytochemical Antcin M is an anti-aging reagent that eliminates hyperglycemia-accelerated premature senescence in dermal fibroblasts by direct activation of Nrf2 and SIRT-1 Research Paper

YM155 sensitizes TRAIL-induced apoptosis through cathepsin S-dependent down-regulation of Mcl-1 and NF-κB-mediated down-regulation of c-FLIP expression in human renal carcinoma Caki cells Research Paper

Stromal remodeling by the BET bromodomain inhibitor JQ1 suppresses the progression of human pancreatic cancer Research Paper

miR-31 targets ARID1A and enhances the oncogenicity and stemness of head and neck squamous cell carcinoma Research Paper

Glypican-3 induces a mesenchymal to epithelial transition in human breast cancer cells Research Paper

C23 promotes tumorigenesis via suppressing p53 activity Research Paper

Regulation of cellular quiescence by YAP/TAZ and Cyclin E1 in colon cancer cells: Implication in chemoresistance and cancer relapse Research Paper

Nucleophosmin/B23 is a negative regulator of estrogen receptor α expression via AP2γ in endometrial cancer cells Research Paper

FOXM1 confers resistance to gefitinib in lung adenocarcinoma via a MET/AKT-dependent positive feedback loop Research Paper

Expression of the p66Shc protein adaptor is regulated by the activator of transcription STAT4 in normal and chronic lymphocytic leukemia B cells Research Paper

Intra-tumoral delivery of functional ID4 protein via PCL/maltodextrin nano-particle inhibits prostate cancer growth Research Paper

IGF-II induced by hepatitis B virus X protein regulates EMT via SUMO mediated loss of E-cadherin in mice Research Paper

Oncostatin M suppresses metastasis of lung adenocarcinoma by inhibiting SLUG expression through coordination of STATs and PIASs signalings Research Paper