The Oncosearch | Oncotarget

Prevalence of actionable mutations and copy number alterations and the price of a genomic testing panel Research Paper

Chan Shen, Funda Meric-Bernstam, Xiaoping Su, John Mendelsohn, Sharon Giordano

Published Sep 13, 2016 · Vol. 7, No. 44 · pp. 71686-71695

Heterozygous mutation of cysteine₅₂₈ in XPO1 is sufficient for resistance to selective inhibitors of nuclear export Research Paper

Jasper Edgar Neggers, Els Vanstreels, Erkan Baloglu, Sharon Shacham, Yosef Landesman, Dirk Daelemans

Published Sep 13, 2016 · Vol. 7, No. 42 · pp. 68842-68850

Blocking downstream signaling pathways in the context of HDAC inhibition promotes apoptosis preferentially in cells harboring mutant Ras Research Paper

Julian C. Bahr, Robert W. Robey, Victoria Luchenko, Agnes Basseville, Arup R. Chakraborty, Hanna Kozlowski, Gary T. Pauly, Paresma Patel, Joel P. Schneider, Michael M. Gottesman, Susan E. Bates

Published Sep 13, 2016 · Vol. 7, No. 43 · pp. 69804-69815

Large variety in a panel of human colon cancer organoids in response to EZH2 inhibition Research Paper

Martijn AJ Koppens, Gergana Bounova, Paulien Cornelissen-Steijger, Nienke de Vries, Owen J Sansom, Lodewyk FA Wessels, Maarten van Lohuizen

Published Sep 13, 2016 · Vol. 7, No. 43 · pp. 69816-69828

Zanthoxylum fruit extract from Japanese pepper promotes autophagic cell death in cancer cells Research Paper

Reo Nozaki, Toru Kono, Hiroki Bochimoto, Tsuyoshi Watanabe, Kaori Oketani, Yuichi Sakamaki, Naoto Okubo, Koji Nakagawa, Hiroshi Takeda

Published Sep 10, 2016 · Vol. 7, No. 43 · pp. 70437-70446

Mutational burdens and evolutionary ages of thyroid follicular adenoma are comparable to those of follicular carcinoma Research Paper

Seung-Hyun Jung, Min Sung Kim, Chan Kwon Jung, Hyun-Chun Park, So Youn Kim, Jieying Liu, Ja-Seong Bae, Sung Hak Lee, Tae-Min Kim, Sug Hyung Lee, Yeun-Jun Chung

Published Sep 9, 2016 · Vol. 7, No. 43 · pp. 69638-69648

The antiangiogenic effects of polyisoprenylated cysteinyl amide inhibitors in HUVEC, chick embryo and zebrafish is dependent on the polyisoprenyl moiety Research Paper

Augustine T. Nkembo, Elizabeth Ntantie, Olufisayo O. Salako, Felix Amissah, Rosemary A. Poku, Lekan M. Latinwo, Nazarius S. Lamango

Published Sep 8, 2016 · Vol. 7, No. 42 · pp. 68194-68205

Acquired resistance to BRAF inhibition in BRAF^V600E mutant gliomas Research Paper

Tsun-Wen Yao, Jie Zhang, Michael Prados, William A. Weiss, C. David James, Theodore Nicolaides

Published Sep 7, 2016 · Vol. 8, No. 1 · pp. 583-595

Clustered somatic mutations are frequent in transcription factor binding motifs within proximal promoter regions in melanoma and other cutaneous malignancies Research Paper

Andrew J. Colebatch, Leon Di Stefano, Stephen Q. Wong, Ross D. Hannan, Paul M. Waring, Alexander Dobrovic, Grant A. McArthur, Anthony T. Papenfuss

Published Sep 7, 2016 · Vol. 7, No. 41 · pp. 66569-66585

STA-8666, a novel HSP90 inhibitor/SN-38 drug conjugate, causes complete tumor regression in preclinical mouse models of pediatric sarcoma Research Paper

Christine M. Heske, Arnulfo Mendoza, Leah D. Edessa, Joshua T. Baumgart, Sunmin Lee, Jane Trepel, David A. Proia, Len Neckers, Lee J. Helman

Published Sep 6, 2016 · Vol. 7, No. 40 · pp. 65540-65552

ATAD2 is an epigenetic reader of newly synthesized histone marks during DNA replication Research Paper

Seong Joo Koo, Amaury E. FernÃ¡ndez-MontalvÃ¡n, Volker Badock, Christopher J. Ott, Simon J. Holton, Oliver von Ahsen, Joern Toedling, Sarah Vittori, James E. Bradner, MÃ¡tyÃ¡s GorjÃ¡nÃ¡cz

Published Sep 6, 2016 · Vol. 7, No. 43 · pp. 70323-70335

Modeling anti-IL-6 therapy using breast cancer patient-derived xenografts Research Paper

Beatriz Morancho, Mariano ZacarÃas-Fluck, Antonio Esgueva, Cristina BernadÃ³-Morales, Serena Di Cosimo, Aleix Prat, Javier CortÃ©s, JoaquÃn Arribas, Isabel T. Rubio

Published Sep 1, 2016 · Vol. 7, No. 42 · pp. 67956-67965

Phase I dose-escalation study of the mTOR inhibitor sirolimus and the HDAC inhibitor vorinostat in patients with advanced malignancy Clinical Research Papers

Haeseong Park, Ignacio Garrido-Laguna, Aung Naing, Siqing Fu, Gerald S. Falchook, Sarina A. Piha-Paul, Jennifer J. Wheler, David S. Hong, Apostolia M. Tsimberidou, Vivek Subbiah, Ralph G. Zinner, Ahmed O. Kaseb, Shreyaskumar Patel, Michelle A. Fanale, Vivianne M. Velez-Bravo, Funda Meric-Bernstam, Razelle Kurzrock, Filip Janku

Published Aug 31, 2016 · Vol. 7, No. 41 · pp. 67521-67531

Concordance between genomic alterations assessed by next-generation sequencing in tumor tissue or circulating cell-free DNA Research Paper

Young Kwang Chae, Andrew A. Davis, Benedito A. Carneiro, Sunandana Chandra, Nisha Mohindra, Aparna Kalyan, Jason Kaplan, Maria Matsangou, Sachin Pai, Ricardo Costa, Borko Jovanovic, Massimo Cristofanilli, Leonidas C. Platanias, Francis J. Giles

Published Aug 30, 2016 · Vol. 7, No. 40 · pp. 65364-65373

p27^kip1 expression limits H-Ras-driven transformation and tumorigenesis by both canonical and non-canonical mechanisms Priority Research Paper

Ilenia Pellizzari, Linda Fabris, Stefania Berton, Ilenia Segatto, Francesca Citron, Sara Dâ€™Andrea, Martina Cusan, Sara Benevol, Tiziana Perin, Samuele Massarut, Vincenzo Canzonieri, Monica Schiappacassi, Barbara Belletti, Gustavo Baldassarre

Published Aug 27, 2016 · Vol. 7, No. 40 · pp. 64560-64574

Novel association of DJ-1 with HER3 potentiates HER3 activation and signaling in cancer Research Paper

Shu Zhang, Seema Mukherjee, Xuejun Fan, Ahmad Salameh, Kalpana Mujoo, Zhao Huang, Leike Li, Georgina Toâ€™a Salazar, Ningyan Zhang, Zhiqiang An

Published Aug 25, 2016 · Vol. 7, No. 40 · pp. 65758-65769

Characterizing and targeting PDGFRA alterations in pediatric high-grade glioma Research Paper

Carl Koschmann, Daniel Zamler, Alan MacKay, Dan Robinson, Yi-Mi Wu, Robert Doherty, Bernard Marini, Dustin Tran, Hugh Garton, Karin Muraszko, Patricia Robertson, Marcia Leonard, Lili Zhao, Dale Bixby, Luke Peterson, Sandra Camelo-Piragua, Chris Jones, Rajen Mody, Pedro R. Lowenstein, Maria G. Castro

Published Aug 25, 2016 · Vol. 7, No. 40 · pp. 65696-65706

Paradoxical overexpression of MBNL2 in hepatocellular carcinoma inhibits tumor growth and invasion Research Paper

Yu-Hsin Lee, Yu-Lin Jhuang, Yu-Ling Chen, Yung-Ming Jeng, Ray-Hwang Yuan

Published Aug 24, 2016 · Vol. 7, No. 40 · pp. 65589-65601

KLRG1 restricts memory T cell antitumor immunity Research Paper

Lei Li, Shanshan Wan, Kaixiong Tao, Guobin Wang, Ende Zhao

Published Aug 20, 2016 · Vol. 7, No. 38 · pp. 61670-61678

CK2 targeted RNAi therapeutic delivered via malignant cell-directed tenfibgen nanocapsule: dose and molecular mechanisms of response in xenograft prostate tumors Research Paper

Khalil Ahmed, Betsy T. Kren, Md. Joynal Abedin, Rachel I. Vogel, Daniel P. Shaughnessy, Lucas Nacusi, Vicci L. Korman, Yingming Li, Scott M. Dehm, Cheryl L. Zimmerman, Gloria A. Niehans, Gretchen M. Unger, Janeen H. Trembley

Published Aug 20, 2016 · Vol. 7, No. 38 · pp. 61789-61805

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Prevalence of actionable mutations and copy number alterations and the price of a genomic testing panel Research Paper

Heterozygous mutation of cysteine₅₂₈ in XPO1 is sufficient for resistance to selective inhibitors of nuclear export Research Paper

Blocking downstream signaling pathways in the context of HDAC inhibition promotes apoptosis preferentially in cells harboring mutant Ras Research Paper

Large variety in a panel of human colon cancer organoids in response to EZH2 inhibition Research Paper

Zanthoxylum fruit extract from Japanese pepper promotes autophagic cell death in cancer cells Research Paper

Mutational burdens and evolutionary ages of thyroid follicular adenoma are comparable to those of follicular carcinoma Research Paper

The antiangiogenic effects of polyisoprenylated cysteinyl amide inhibitors in HUVEC, chick embryo and zebrafish is dependent on the polyisoprenyl moiety Research Paper

Acquired resistance to BRAF inhibition in BRAF^V600E mutant gliomas Research Paper

Clustered somatic mutations are frequent in transcription factor binding motifs within proximal promoter regions in melanoma and other cutaneous malignancies Research Paper

STA-8666, a novel HSP90 inhibitor/SN-38 drug conjugate, causes complete tumor regression in preclinical mouse models of pediatric sarcoma Research Paper

ATAD2 is an epigenetic reader of newly synthesized histone marks during DNA replication Research Paper

Modeling anti-IL-6 therapy using breast cancer patient-derived xenografts Research Paper

Phase I dose-escalation study of the mTOR inhibitor sirolimus and the HDAC inhibitor vorinostat in patients with advanced malignancy Clinical Research Papers

Concordance between genomic alterations assessed by next-generation sequencing in tumor tissue or circulating cell-free DNA Research Paper

p27^kip1 expression limits H-Ras-driven transformation and tumorigenesis by both canonical and non-canonical mechanisms Priority Research Paper

Novel association of DJ-1 with HER3 potentiates HER3 activation and signaling in cancer Research Paper

Characterizing and targeting PDGFRA alterations in pediatric high-grade glioma Research Paper

Paradoxical overexpression of MBNL2 in hepatocellular carcinoma inhibits tumor growth and invasion Research Paper

KLRG1 restricts memory T cell antitumor immunity Research Paper

CK2 targeted RNAi therapeutic delivered via malignant cell-directed tenfibgen nanocapsule: dose and molecular mechanisms of response in xenograft prostate tumors Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Prevalence of actionable mutations and copy number alterations and the price of a genomic testing panel Research Paper

Heterozygous mutation of cysteine528 in XPO1 is sufficient for resistance to selective inhibitors of nuclear export Research Paper

Blocking downstream signaling pathways in the context of HDAC inhibition promotes apoptosis preferentially in cells harboring mutant Ras Research Paper

Large variety in a panel of human colon cancer organoids in response to EZH2 inhibition Research Paper

Zanthoxylum fruit extract from Japanese pepper promotes autophagic cell death in cancer cells Research Paper

Mutational burdens and evolutionary ages of thyroid follicular adenoma are comparable to those of follicular carcinoma Research Paper

The antiangiogenic effects of polyisoprenylated cysteinyl amide inhibitors in HUVEC, chick embryo and zebrafish is dependent on the polyisoprenyl moiety Research Paper

Acquired resistance to BRAF inhibition in BRAFV600E mutant gliomas Research Paper

Clustered somatic mutations are frequent in transcription factor binding motifs within proximal promoter regions in melanoma and other cutaneous malignancies Research Paper

STA-8666, a novel HSP90 inhibitor/SN-38 drug conjugate, causes complete tumor regression in preclinical mouse models of pediatric sarcoma Research Paper

ATAD2 is an epigenetic reader of newly synthesized histone marks during DNA replication Research Paper

Modeling anti-IL-6 therapy using breast cancer patient-derived xenografts Research Paper

Phase I dose-escalation study of the mTOR inhibitor sirolimus and the HDAC inhibitor vorinostat in patients with advanced malignancy Clinical Research Papers

Concordance between genomic alterations assessed by next-generation sequencing in tumor tissue or circulating cell-free DNA Research Paper

p27kip1 expression limits H-Ras-driven transformation and tumorigenesis by both canonical and non-canonical mechanisms Priority Research Paper

Novel association of DJ-1 with HER3 potentiates HER3 activation and signaling in cancer Research Paper

Characterizing and targeting PDGFRA alterations in pediatric high-grade glioma Research Paper

Paradoxical overexpression of MBNL2 in hepatocellular carcinoma inhibits tumor growth and invasion Research Paper

KLRG1 restricts memory T cell antitumor immunity Research Paper

CK2 targeted RNAi therapeutic delivered via malignant cell-directed tenfibgen nanocapsule: dose and molecular mechanisms of response in xenograft prostate tumors Research Paper

Heterozygous mutation of cysteine₅₂₈ in XPO1 is sufficient for resistance to selective inhibitors of nuclear export Research Paper

Acquired resistance to BRAF inhibition in BRAF^V600E mutant gliomas Research Paper

p27^kip1 expression limits H-Ras-driven transformation and tumorigenesis by both canonical and non-canonical mechanisms Priority Research Paper