The Oncosearch | Oncotarget

cGAS-STING pathway in oncogenesis and cancer therapeutics Review

Brandon Yi Da Hoong, Yunn Hwen Gan, Haiyan Liu, Ee Sin Chen

Published Jun 30, 2020 · Vol. 11, No. 30 · pp. 2930-2955

Keywords: cyclic GMP-AMP synthase, stimulator of interferon, cGAS, STING, interferon

Epigenetic feedback and stochastic partitioning during cell division can drive resistance to EMT Research Paper

Wen Jia, Shubham Tripathi, Priyanka Chakraborty, Adithya Chedere, Annapoorni Rangarajan, Herbert Levine, Mohit Kumar Jolly

Published Jun 11, 2020 · Vol. 11, No. 27 · pp. 2611-2624

Keywords: epithelial-mesenchymal transition, mesenchymal-epithelial transition, GRHL2, epigenetics, asymmetric cell division

Discovery of fifteen new geroprotective plant extracts and identification of cellular processes they affect to prolong the chronological lifespan of budding yeast Research Paper

Pamela Dakik, Monica Enith Lozano Rodriguez, Jennifer Anne Baratang Junio, Darya Mitrofanova, Younes Medkour, Tala Tafakori, Tarek Taifour, Vicky Lutchman, Eugenie Samson, Anthony Arlia-Ciommo, Belise Rukundo, Éric Simard, Vladimir I. Titorenko

Published May 23, 2020 · Vol. 11, No. 23 · pp. 2182-2203

Keywords: cellular aging, longevity, gerotargets, geroprotectors, plant extracts

miR-708-5p targets oncogenic prostaglandin E2 production to suppress a pro-tumorigenic phenotype in lung cancer cells Research Paper

Nicholas J. Monteleone, Carol S. Lutz

Published May 22, 2020 · Vol. 11, No. 26 · pp. 2464-2483

Keywords: miR-708-5p, miR-708, lung cancer, COX-2, mPGES-1

Both BRCA1-wild type and -mutant triple-negative breast cancers show sensitivity to the NAE inhibitor MLN4924 which is enhanced upon MLN4924 and cisplatin combination treatment Research Paper

Shrilekha Misra, Xiaoli Zhang, Nissar Ahmad Wani, Steven Sizemore, Alo Ray

Published Feb 25, 2020 · Vol. 11, No. 8 · pp. 784-800

Keywords: triple-negative breast cancer, MLN4924, cisplatin, cell cycle, DNA damage

The targeted LHRH analog AEZS-108 alters expression of genes related to angiogenesis and development of metastasis in uveal melanoma Research Paper

Klara Fodor, Nikoletta Dobos, Andrew Schally, Zita Steiber, Gabor Olah, Eva Sipos, Lorant Szekvolgyi, Gabor Halmos

Published Jan 14, 2020 · Vol. 11, No. 2 · pp. 175-187

Keywords: uveal melanoma, luteinizing hormone-releasing hormone (LHRH) receptor, angiogenesis, MASPIN/SERPINB5, AEZS-108 (AN-152/Zoptarelin Doxorubicin Acetate)

Low-dose metronomic cyclophosphamide complements the actions of an intratumoral C-class CpG TLR9 agonist to potentiate innate immunity and drive potent T cell-mediated anti-tumor responses Research Paper

Weng In Leong, Rachel Y. Ames, Jessica M. Haverkamp, Laura Torres, Janine Kline, Ashil Bans, Lauren Rocha, Marilena Gallotta, Cristiana Guiducci, Robert L. Coffman, Mary J. Janatpour

Published Dec 31, 2019 · Vol. 10, No. 68 · pp. 7220-7237

Keywords: TLR9, SD-101, cyclophosphamide, immune therapy, innate immunity

A side-by-side evaluation of [¹⁸F]FDOPA enantiomers for non-invasive detection of neuroendocrine tumors by positron emission tomography Research Paper

Athira Narayan, Yu Yan, Ala Lisok, Mary Brummet, Martin G. Pomper, Wojciech G. Lesniak, Robert F. Dannals, Vanessa F. Merino, Babak Behnam Azad

Published Oct 8, 2019 · Vol. 10, No. 56 · pp. 5731-5744

Keywords: FDOPA, PET, neuroendocrine tumors, Fluorine-18, molecular imaging

Mechanisms by which PE21, an extract from the white willow Salix alba, delays chronological aging in budding yeast Research Paper

Younes Medkour, Karamat Mohammad, Anthony Arlia-Ciommo, Veronika Svistkova, Pamela Dakik, Darya Mitrofanova, Monica Enith Lozano Rodriguez, Jennifer Anne Baratang Junio, Tarek Taifour, Paola Escudero, Fani-Fay Goltsios, Sahar Soodbakhsh, Hana Maalaoui, Éric Simard, Vladimir I. Titorenko

Published Oct 8, 2019 · Vol. 10, No. 56 · pp. 5780-5816

Keywords: cellular aging, geroprotectors, lipid metabolism, necrotic cell death, mitochondria

SMR peptide antagonizes mortalin promoted release of extracellular vesicles and affects mortalin protection from complement-dependent cytotoxicity in breast cancer cells and leukemia cells Research Paper

Ming-Bo Huang, Jennifer Y. Wu, James Lillard, Vincent C. Bond

Published Sep 10, 2019 · Vol. 10, No. 52 · pp. 5419-5438

Keywords: extracellular vesicles, mortalin, complement, SMR peptides, breast cancer

Mechanisms by which PE21, an extract from the white willow Salix alba, delays chronological aging in budding yeast Research Paper

Younes Medkour, Karamat Mohammad, Anthony Arlia-Ciommo, Veronika Svistkova, Pamela Dakik, Darya Mitrofanova, Monica Enith Lozano Rodriguez, Jennifer Anne Baratang Junio, Tarek Taifour, Paola Escudero, Fani-Fay Goltsios, Sahar Soodbakhsh, Hana Maalaoui, Éric Simard, Vladimir I. Titorenko

Published Sep 5, 2019

Keywords: cellular aging, geroprotectors, lipid metabolism, necrotic cell death, mitochondria

Exosome-based detection of activating and resistance EGFR mutations from plasma of non-small cell lung cancer patients Research Paper

Elena Castellanos-Rizaldos, Xuan Zhang, Vasisht R. Tadigotla, Dominik G. Grimm, Chris Karlovich, Luis E. Raez, Johan K. Skog

Published Apr 23, 2019 · Vol. 10, No. 30 · pp. 2911-2920

Keywords: liquid biopsy, exosomes, ctDNA, exoNA, NSCLC

Synthetic lethality of a cell-penetrating anti-RAD51 antibody in PTEN-deficient melanoma and glioma cells Priority Research Paper

Audrey Turchick, Yanfeng Liu, Weixi Zhao, Inessa Cohen, Peter M. Glazer

Published Feb 12, 2019 · Vol. 10, No. 13 · pp. 1272-1283

SETD2 loss sensitizes cells to PI3KÎ² and AKT inhibition Research Paper

Esteban A. Terzo, Aaron R. Lim, Anna Chytil, Yun Chen Chiang, Leah Farmer, Kathryn H. Gessner, Cheryl Lyn Walker, Valerie M. Jansen, W. Kimryn Rathmell

Published Jan 18, 2019 · Vol. 10, No. 6 · pp. 647-659

Simplifying checkpoint inhibitor delivery through in vivo generation of synthetic DNA-encoded monoclonal antibodies (DMAbs) Research Perspective

Alfredo Perales-Puchalt, Elizabeth K. Duperret, Kar Muthumani, David B. Weiner

Published Jan 1, 2019 · Vol. 10, No. 1 · pp. 13-16

Eradication of LIG4-deficient glioblastoma cells by the combination of PARP inhibitor and alkylating agent Research Paper

Monika Toma, Monika Witusik-Perkowska, Marzena Szwed, Robert Stawski, Janusz Szemraj, Malgorzata Drzewiecka, Margaret Nieborowska-Skorska, Maciej Radek, Pawel Kolasa, Ksenia Matlawska-Wasowska, Tomasz Sliwinski, Tomasz Skorski

Published Dec 7, 2018 · Vol. 9, No. 96 · pp. 36867-36877

Synthetic lethal combinations of low-toxicity drugs for breast cancer identified in silico by genetic screens in yeast Research Paper

Maximilian Marhold, Erwin Tomasich, Michael Schwarz, Simon Udovica, Andreas Heinzel, Paul Mayer, Peter Horak, Paul Perco, Michael Krainer

Published Nov 20, 2018 · Vol. 9, No. 91 · pp. 36379-36391

Inhibition of breast cancer metastasis to the lungs with UBS109 Research Paper

Mamoru Shoji, Wei Ping Qian, Ganji Purnachandra Nagaraju, Daniel J. Brat, Danielle Pessolano, Rick Luzietti, Spandan Chennamadhavuni, Masayoshi Yamaguchi, Lily Yang, Dennis C. Liotta

Published Nov 16, 2018 · Vol. 9, No. 90 · pp. 36102-36109

Personalized identification of tumor-associated immunogenic neoepitopes in hepatocellular carcinoma in complete remission after sorafenib treatment Research Paper

Sindy Vrecko, David Guenat, Patricia Mercier-Letondal, Hugues Faucheu, Magalie Dosset, Bernard Royer, Jeanne Galaine, Romain Boidot, Stefano Kim, Marine Jary, Olivier AdotÃ©vi, Christophe Borg, Yann Godet

Published Oct 23, 2018 · Vol. 9, No. 83 · pp. 35394-35407

PARP1 is required for preserving telomeric integrity but is dispensable for A-NHEJ Research Paper

Adam Harvey, Nicholas Mielke, Julia W. Grimstead, Rhiannon E. Jones, Thanh Nguyen, Matthew Mueller, Duncan M. Baird, Eric A. Hendrickson

Published Oct 5, 2018 · Vol. 9, No. 78 · pp. 34821-34837

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European Cancer and Oncology Congress

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cGAS-STING pathway in oncogenesis and cancer therapeutics Review

Epigenetic feedback and stochastic partitioning during cell division can drive resistance to EMT Research Paper

Discovery of fifteen new geroprotective plant extracts and identification of cellular processes they affect to prolong the chronological lifespan of budding yeast Research Paper

miR-708-5p targets oncogenic prostaglandin E2 production to suppress a pro-tumorigenic phenotype in lung cancer cells Research Paper

Both BRCA1-wild type and -mutant triple-negative breast cancers show sensitivity to the NAE inhibitor MLN4924 which is enhanced upon MLN4924 and cisplatin combination treatment Research Paper

The targeted LHRH analog AEZS-108 alters expression of genes related to angiogenesis and development of metastasis in uveal melanoma Research Paper

Low-dose metronomic cyclophosphamide complements the actions of an intratumoral C-class CpG TLR9 agonist to potentiate innate immunity and drive potent T cell-mediated anti-tumor responses Research Paper

A side-by-side evaluation of [¹⁸F]FDOPA enantiomers for non-invasive detection of neuroendocrine tumors by positron emission tomography Research Paper

Mechanisms by which PE21, an extract from the white willow Salix alba, delays chronological aging in budding yeast Research Paper

SMR peptide antagonizes mortalin promoted release of extracellular vesicles and affects mortalin protection from complement-dependent cytotoxicity in breast cancer cells and leukemia cells Research Paper

Mechanisms by which PE21, an extract from the white willow Salix alba, delays chronological aging in budding yeast Research Paper

Exosome-based detection of activating and resistance EGFR mutations from plasma of non-small cell lung cancer patients Research Paper

Synthetic lethality of a cell-penetrating anti-RAD51 antibody in PTEN-deficient melanoma and glioma cells Priority Research Paper

SETD2 loss sensitizes cells to PI3KÎ² and AKT inhibition Research Paper

Simplifying checkpoint inhibitor delivery through in vivo generation of synthetic DNA-encoded monoclonal antibodies (DMAbs) Research Perspective

Eradication of LIG4-deficient glioblastoma cells by the combination of PARP inhibitor and alkylating agent Research Paper

Synthetic lethal combinations of low-toxicity drugs for breast cancer identified in silico by genetic screens in yeast Research Paper

Inhibition of breast cancer metastasis to the lungs with UBS109 Research Paper

Personalized identification of tumor-associated immunogenic neoepitopes in hepatocellular carcinoma in complete remission after sorafenib treatment Research Paper

PARP1 is required for preserving telomeric integrity but is dispensable for A-NHEJ Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

cGAS-STING pathway in oncogenesis and cancer therapeutics Review

Epigenetic feedback and stochastic partitioning during cell division can drive resistance to EMT Research Paper

Discovery of fifteen new geroprotective plant extracts and identification of cellular processes they affect to prolong the chronological lifespan of budding yeast Research Paper

miR-708-5p targets oncogenic prostaglandin E2 production to suppress a pro-tumorigenic phenotype in lung cancer cells Research Paper

Both BRCA1-wild type and -mutant triple-negative breast cancers show sensitivity to the NAE inhibitor MLN4924 which is enhanced upon MLN4924 and cisplatin combination treatment Research Paper

The targeted LHRH analog AEZS-108 alters expression of genes related to angiogenesis and development of metastasis in uveal melanoma Research Paper

Low-dose metronomic cyclophosphamide complements the actions of an intratumoral C-class CpG TLR9 agonist to potentiate innate immunity and drive potent T cell-mediated anti-tumor responses Research Paper

A side-by-side evaluation of [18F]FDOPA enantiomers for non-invasive detection of neuroendocrine tumors by positron emission tomography Research Paper

Mechanisms by which PE21, an extract from the white willow Salix alba, delays chronological aging in budding yeast Research Paper

SMR peptide antagonizes mortalin promoted release of extracellular vesicles and affects mortalin protection from complement-dependent cytotoxicity in breast cancer cells and leukemia cells Research Paper

Mechanisms by which PE21, an extract from the white willow Salix alba, delays chronological aging in budding yeast Research Paper

Exosome-based detection of activating and resistance EGFR mutations from plasma of non-small cell lung cancer patients Research Paper

Synthetic lethality of a cell-penetrating anti-RAD51 antibody in PTEN-deficient melanoma and glioma cells Priority Research Paper

SETD2 loss sensitizes cells to PI3KÎ² and AKT inhibition Research Paper

Simplifying checkpoint inhibitor delivery through in vivo generation of synthetic DNA-encoded monoclonal antibodies (DMAbs) Research Perspective

Eradication of LIG4-deficient glioblastoma cells by the combination of PARP inhibitor and alkylating agent Research Paper

Synthetic lethal combinations of low-toxicity drugs for breast cancer identified in silico by genetic screens in yeast Research Paper

Inhibition of breast cancer metastasis to the lungs with UBS109 Research Paper

Personalized identification of tumor-associated immunogenic neoepitopes in hepatocellular carcinoma in complete remission after sorafenib treatment Research Paper

PARP1 is required for preserving telomeric integrity but is dispensable for A-NHEJ Research Paper

A side-by-side evaluation of [¹⁸F]FDOPA enantiomers for non-invasive detection of neuroendocrine tumors by positron emission tomography Research Paper