The Oncosearch | Oncotarget

Knock-in of the Wt1 R394W mutation causes MDS and cooperates with Flt3/ITD to drive aggressive myeloid neoplasms in mice Research Paper

Colleen E. Annesley, Cara Rabik, Amy S. Duffield, Rachel E. Rau, Daniel Magoon, Li Li, Vicki Huff, Donald Small, David M. Loeb, Patrick Brown

Published Oct 19, 2018 · Vol. 9, No. 82 · pp. 35313-35326

Molecular analysis of the dual targeting of the epidermal growth factor receptor and the O⁶-methylguanine-DNA methyltransferase with a double arm hybrid molecule Research Paper

Martin Rupp, Zhor Senhaji Mouhri, Christopher Williams, Bertrand J. Jean-Claude

Published Oct 12, 2018 · Vol. 9, No. 80 · pp. 35041-35055

IDH1^R132H is intrinsically tumor-suppressive but functionally attenuated by the glutamate-rich cerebral environment Research Paper

Patricia D.B. Tiburcio, Bing Xiao, Yi Chai, Sydney Asper, Sheryl R. Tripp, David L. Gillespie, Randy L. Jensen, L. Eric Huang

Published Oct 12, 2018 · Vol. 9, No. 80 · pp. 35100-35113

Aldoxorubicin and Temozolomide combination in a xenograft mice model of human glioblastoma Research Paper

Martina Da Ros, Anna Lisa Iorio, Veronica De Gregorio, Ornella FantappiÃ¨, Giacomo Laffi, Maurizio de Martino, Claudio Pisano, Lorenzo Genitori, Iacopo Sardi

Published Oct 9, 2018 · Vol. 9, No. 79 · pp. 34935-34944

Generation and characterization of novel recombinant anti-hERG1 scFv antibodies for cancer molecular imaging Research Paper

Claudia Duranti, Laura Carraresi, Angelica Sette, Matteo Stefanini, Tiziano Lottini, Silvia Crescioli, Olivia Crociani, Luisa Iamele, Hugo De Jonge, Ermanno Gherardi, Annarosa Arcangeli

Published Oct 9, 2018 · Vol. 9, No. 79 · pp. 34972-34989

MEK/CDK4,6 co-targeting is effective in a subset of NRAS, BRAF and 'wild type' melanomas Research Paper

Christian Posch, Martina Sanlorenzo, Jeffrey Ma, Sarasa T. Kim, Mitchell Zekhtser, Susana Ortiz-Urda

Published Oct 9, 2018 · Vol. 9, No. 79 · pp. 34990-34995

PARP1 is required for preserving telomeric integrity but is dispensable for A-NHEJ Research Paper

Adam Harvey, Nicholas Mielke, Julia W. Grimstead, Rhiannon E. Jones, Thanh Nguyen, Matthew Mueller, Duncan M. Baird, Eric A. Hendrickson

Published Oct 5, 2018 · Vol. 9, No. 78 · pp. 34821-34837

XPO1 inhibition by selinexor induces potent cytotoxicity against high grade bladder malignancies Research Paper

Han Bit Baek, Alan P. Lombard, Stephen J. Libertini, Aleida Fernandez-Rubio, Ruth Vinall, Regina Gandour-Edwards, Rachel Nakagawa, Kathleen Vidallo, Kristine Nishida, Salma Siddiqui, Hiromi Wettersten, Yosef Landesman, Robert H. Weiss, Paramita M. Ghosh, Maria Mudryj

Published Oct 2, 2018 · Vol. 9, No. 77 · pp. 34567-34581

Functional characterization of phospholipase C-Î³₂ mutant protein causing both somatic ibrutinib resistance and a germline monogenic autoinflammatory disorder Research Paper

Claudia Walliser, Martin Wist, Elisabeth Hermkes, Yuan Zhou, Anja Schade, Jennifer Haas, Julia Deinzer, Laurent DÃ©sirÃ©, Shawn S.C. Li, Stephan Stilgenbauer, Joshua D. Milner, Peter Gierschik

Published Sep 28, 2018 · Vol. 9, No. 76 · pp. 34357-34378

Clearance of HBeAg and HBsAg of HBV in mice model by a recombinant HBV vaccine combined with GM-CSF and IFN-Î± as an effective therapeutic vaccine adjuvant Research Paper

Weidong Zhao, Gan Zhao, Shuren Zhang, Xianzheng Wang, Xueping Yu, Bin Wang

Published Sep 28, 2018 · Vol. 9, No. 76 · pp. 34213-34228

Heat shock protein 90 inhibitors overcome the resistance to Fms-like tyrosine kinase 3 inhibitors in acute myeloid leukemia Research Paper

Kazuhiro Katayama, Kohji Noguchi, Yoshikazu Sugimoto

Published Sep 28, 2018 · Vol. 9, No. 76 · pp. 34240-34258

Genetic and epigenetic analyses guided by high resolution whole-genome SNP array reveals a possible role of CHEK2 in Wilms tumour susceptibility Research Paper

Sara Ciceri, Beatrice Gamba, Paola Corbetta, Patrizia Mondini, Monica Terenziani, Serena Catania, Marilina Nantron, Maurizio Bianchi, Paolo Dâ€™Angelo, Federica Torri, Fabio Macciardi, Paola Collini, Martina Di Martino, Fraia Melchionda, Andrea Di Cataldo, Filippo Spreafico, Paolo Radice, Daniela Perotti, on behalf of the AIEOP study group

Published Sep 25, 2018 · Vol. 9, No. 75 · pp. 34079-34089

Rapid detection of copy number variations and point mutations in BRCA1/2 genes using a single workflow by ion semiconductor sequencing pipeline Research Paper

Aldo Germani, Fabio Libi, Stefano Maggi, Gianluca Stanzani, Augusto Lombardi, Patrizia Pellegrini, Mauro Mattei, Laura De Marchis, Claudio Amanti, Antonio Pizzuti, Maria Rosaria Torrisi, Maria Piane

Published Sep 14, 2018 · Vol. 9, No. 72 · pp. 33648-33655

RN765C, a low affinity EGFR antibody drug conjugate with potent anti-tumor activity in preclinical solid tumor models Priority Research Paper

Oi Kwan Wong, Thomas-Toan Tran, Wei-Hsien Ho, Meritxell Galindo Casas, Melinda Au, Marjorie Bateman, Kevin C. Lindquist, Arvind Rajpal, David L. Shelton, Pavel Strop, Shu-Hui Liu

Published Sep 11, 2018 · Vol. 9, No. 71 · pp. 33446-33458

Single-cell transcriptomes reveal the mechanism for a breast cancer prognostic gene panel Research Paper

Shengwen Calvin Li, Andres Stucky, Xuelian Chen, Mustafa H. Kabeer, William G. Loudon, Ashley S. Plant, Lilibeth Torno, Chaitali S. Nangia, Jin Cai, Gang Zhang, Jiang F. Zhong

Published Sep 7, 2018 · Vol. 9, No. 70 · pp. 33290-33301

Quantitative screening of serum protein biomarkers by reverse phase protein arrays Research Paper

Zhizhou Kuang, Ruochun Huang, Zhimin Yang, Zhiqiang Lv, Xinyan Chen, Fuping Xu, Yu-Hua Yi, Jian Wu, Ruo-Pan Huang

Published Aug 24, 2018 · Vol. 9, No. 66 · pp. 32624-32641

Genomic mutations and histopathologic biomarkers in Y⁹⁰ radioembolization for chemorefractory colorectal liver metastases Research Paper

Meaghan S. Dendy, Johannes M. Ludwig, Nima Kokabi, Stacey M. Stein, Jill Lacy, Howard S. Hochster, Hyun S. Kim

Published Aug 21, 2018 · Vol. 9, No. 65 · pp. 32523-32533

Erratum: Will PI3K pathway inhibitors be effective as single agents in patients with cancer? Errata

Joan T. Garrett, Anindita Chakrabarty, Carlos L. Arteaga

Published Aug 17, 2018 · Vol. 9, No. 64 · pp. 32400-32400

Race and nodal disease status are prognostic factors in patients with stage IVB cervical cancer Research Paper

Shin Nishio, Koji Matsuo, Koji Yonemoto, Mototsugu Shimokawa, Masayuki Hosaka, Michiko Kodama, Takahito M. Miyake, Kimio Ushijima, Toshiharu Kamura, Shannon N. Westin, Pamela T. Soliman, Robert L. Coleman

Published Aug 17, 2018 · Vol. 9, No. 64 · pp. 32321-32330

Wild-type p53 oligomerizes more efficiently than p53 hot-spot mutants and overcomes mutant p53 gain-of-function via a "dominant-positive" mechanism Research Paper

Dawid Walerych, Magdalena Pruszko, Lukasz Zyla, Michalina Wezyk, Katarzyna Gaweda-Walerych, Alicja Zylicz

Published Aug 10, 2018 · Vol. 9, No. 62 · pp. 32063-32080

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Knock-in of the Wt1 R394W mutation causes MDS and cooperates with Flt3/ITD to drive aggressive myeloid neoplasms in mice Research Paper

Molecular analysis of the dual targeting of the epidermal growth factor receptor and the O⁶-methylguanine-DNA methyltransferase with a double arm hybrid molecule Research Paper

IDH1^R132H is intrinsically tumor-suppressive but functionally attenuated by the glutamate-rich cerebral environment Research Paper

Aldoxorubicin and Temozolomide combination in a xenograft mice model of human glioblastoma Research Paper

Generation and characterization of novel recombinant anti-hERG1 scFv antibodies for cancer molecular imaging Research Paper

MEK/CDK4,6 co-targeting is effective in a subset of NRAS, BRAF and 'wild type' melanomas Research Paper

PARP1 is required for preserving telomeric integrity but is dispensable for A-NHEJ Research Paper

XPO1 inhibition by selinexor induces potent cytotoxicity against high grade bladder malignancies Research Paper

Functional characterization of phospholipase C-Î³₂ mutant protein causing both somatic ibrutinib resistance and a germline monogenic autoinflammatory disorder Research Paper

Clearance of HBeAg and HBsAg of HBV in mice model by a recombinant HBV vaccine combined with GM-CSF and IFN-Î± as an effective therapeutic vaccine adjuvant Research Paper

Heat shock protein 90 inhibitors overcome the resistance to Fms-like tyrosine kinase 3 inhibitors in acute myeloid leukemia Research Paper

Genetic and epigenetic analyses guided by high resolution whole-genome SNP array reveals a possible role of CHEK2 in Wilms tumour susceptibility Research Paper

Rapid detection of copy number variations and point mutations in BRCA1/2 genes using a single workflow by ion semiconductor sequencing pipeline Research Paper

RN765C, a low affinity EGFR antibody drug conjugate with potent anti-tumor activity in preclinical solid tumor models Priority Research Paper

Single-cell transcriptomes reveal the mechanism for a breast cancer prognostic gene panel Research Paper

Quantitative screening of serum protein biomarkers by reverse phase protein arrays Research Paper

Genomic mutations and histopathologic biomarkers in Y⁹⁰ radioembolization for chemorefractory colorectal liver metastases Research Paper

Erratum: Will PI3K pathway inhibitors be effective as single agents in patients with cancer? Errata

Race and nodal disease status are prognostic factors in patients with stage IVB cervical cancer Research Paper

Wild-type p53 oligomerizes more efficiently than p53 hot-spot mutants and overcomes mutant p53 gain-of-function via a "dominant-positive" mechanism Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Knock-in of the Wt1 R394W mutation causes MDS and cooperates with Flt3/ITD to drive aggressive myeloid neoplasms in mice Research Paper

Molecular analysis of the dual targeting of the epidermal growth factor receptor and the O6-methylguanine-DNA methyltransferase with a double arm hybrid molecule Research Paper

IDH1R132H is intrinsically tumor-suppressive but functionally attenuated by the glutamate-rich cerebral environment Research Paper

Aldoxorubicin and Temozolomide combination in a xenograft mice model of human glioblastoma Research Paper

Generation and characterization of novel recombinant anti-hERG1 scFv antibodies for cancer molecular imaging Research Paper

MEK/CDK4,6 co-targeting is effective in a subset of NRAS, BRAF and 'wild type' melanomas Research Paper

PARP1 is required for preserving telomeric integrity but is dispensable for A-NHEJ Research Paper

XPO1 inhibition by selinexor induces potent cytotoxicity against high grade bladder malignancies Research Paper

Functional characterization of phospholipase C-Î³2 mutant protein causing both somatic ibrutinib resistance and a germline monogenic autoinflammatory disorder Research Paper

Clearance of HBeAg and HBsAg of HBV in mice model by a recombinant HBV vaccine combined with GM-CSF and IFN-Î± as an effective therapeutic vaccine adjuvant Research Paper

Heat shock protein 90 inhibitors overcome the resistance to Fms-like tyrosine kinase 3 inhibitors in acute myeloid leukemia Research Paper

Genetic and epigenetic analyses guided by high resolution whole-genome SNP array reveals a possible role of CHEK2 in Wilms tumour susceptibility Research Paper

Rapid detection of copy number variations and point mutations in BRCA1/2 genes using a single workflow by ion semiconductor sequencing pipeline Research Paper

RN765C, a low affinity EGFR antibody drug conjugate with potent anti-tumor activity in preclinical solid tumor models Priority Research Paper

Single-cell transcriptomes reveal the mechanism for a breast cancer prognostic gene panel Research Paper

Quantitative screening of serum protein biomarkers by reverse phase protein arrays Research Paper

Genomic mutations and histopathologic biomarkers in Y90 radioembolization for chemorefractory colorectal liver metastases Research Paper

Erratum: Will PI3K pathway inhibitors be effective as single agents in patients with cancer? Errata

Race and nodal disease status are prognostic factors in patients with stage IVB cervical cancer Research Paper

Wild-type p53 oligomerizes more efficiently than p53 hot-spot mutants and overcomes mutant p53 gain-of-function via a "dominant-positive" mechanism Research Paper

Molecular analysis of the dual targeting of the epidermal growth factor receptor and the O⁶-methylguanine-DNA methyltransferase with a double arm hybrid molecule Research Paper

IDH1^R132H is intrinsically tumor-suppressive but functionally attenuated by the glutamate-rich cerebral environment Research Paper

Functional characterization of phospholipase C-Î³₂ mutant protein causing both somatic ibrutinib resistance and a germline monogenic autoinflammatory disorder Research Paper

Genomic mutations and histopathologic biomarkers in Y⁹⁰ radioembolization for chemorefractory colorectal liver metastases Research Paper