The Oncosearch | Oncotarget

CD44 promotes multi-drug resistance by protecting P-glycoprotein from FBXO21-mediated ubiquitination Research Paper

Abhilash K. Ravindranath, Swayamjot Kaur, Roman P. Wernyj, Muthu N. Kumaran, Karl E. Miletti-Gonzalez, Rigel Chan, Elaine Lim, Kiran Madura, Lorna Rodriguez-Rodriguez

Published Jul 3, 2015 · Vol. 6, No. 28 · pp. 26308-26321

Anti-tumoral effect of desmethylclomipramine in lung cancer stem cells Priority Research Paper

Lucilla Bongiorno-Borbone, Arianna Giacobbe, Mirco Compagnone, Adriana Eramo, Ruggero De Maria, Angelo Peschiaroli, Gerry Melino

Published Jul 1, 2015 · Vol. 6, No. 19 · pp. 16926-16938

Critical role of Wnt/Î²-catenin signaling in driving epithelial ovarian cancer platinum resistance Research Paper

Anil Belur Nagaraj, Peronne Joseph, Olga Kovalenko, Sareena Singh, Amy Armstrong, Raymond Redline, Kimberly Resnick, Kristine Zanotti, Steven Waggoner, Analisa DiFeo

Published Jun 29, 2015 · Vol. 6, No. 27 · pp. 23720-23734

SERPINA1 is a direct estrogen receptor target gene and a predictor of survival in breast cancer patients Research Paper

Hei Jason Chan, Haiqing Li, Zheng Liu, Yate-Ching Yuan, Joanne Mortimer, Shiuan Chen

Published Jun 29, 2015 · Vol. 6, No. 28 · pp. 25815-25827

Growth arrest DNA damage-inducible gene 45 gamma expression as a prognostic and predictive biomarker in hepatocellular carcinoma Research Paper

Da-Liang Ou, Song-Kun Shyue, Liang-In Lin, Zi-Rui Feng, Jun-Yang Liou, Hsiang-Hsuan Fan, Bin-Shyun Lee, Chiun Hsu, Ann-Lii Cheng

Published Jun 29, 2015 · Vol. 6, No. 29 · pp. 27953-27965

Phosphorylation of apoptosis repressor with caspase recruitment domain by protein kinase CK2 contributes to chemotherapy resistance by inhibiting doxorubicin induced apoptosis Research Paper

Jianxun Wang, Chang Feng, Yuqi He, Wei Ding, Jianqiu Sheng, Muhammad Arshad, Xiaojie Zhang, Peifeng Li

Published Jun 27, 2015 · Vol. 6, No. 29 · pp. 27700-27713

Keywords: chemotherapy resistance, ARC, CK2, apoptosis, doxorubicin

Folate deficiency-triggered redox pathways confer drug resistance in hepatocellular carcinoma Research Paper

Chun-Te Ho, Hung-Sheng Shang, Jin-Biou Chang, Jun-Jen Liu, Tsan-Zon Liu

Published Jun 27, 2015 · Vol. 6, No. 28 · pp. 26104-26118

ErbB-3 activation by NRG-1Î² sustains growth and promotes vemurafenib resistance in BRAF-V600E colon cancer stem cells (CSCs) Priority Research Paper

Pramudita R. Prasetyanti, Emily Capone, Daniela Barcaroli, Daniela Dâ€™Agostino, Silvia Volpe, Antonina Benfante, Sander van Hooff, Valentina Iacobelli, Cosmo Rossi, Stefano Iacobelli, Jan Paul Medema, Vincenzo De Laurenzi, Gianluca Sala

Published Jun 25, 2015 · Vol. 6, No. 19 · pp. 16902-16911

Lovastatin overcomes gefitinib resistance through TNF-α signaling in human cholangiocarcinomas with different LKB1 statuses in vitro and in vivo Research Paper

Sheng-Huei Yang, Hung-Yun Lin, Vincent H.S. Chang, Chien-Chung Chen, Yun-Ru Liu, Jinghan Wang, Keqiang Zhang, Xiaoqing Jiang, Yun Yen

Published Jun 23, 2015 · Vol. 6, No. 27 · pp. 23857-23873

Keywords: Cholangiocarcinomas, Combination therapy, Lovastatin, Gefitinib

A NOX2/Egr-1/Fyn pathway delineates new targets for TKI-resistant malignancies Research Paper

Mary E. Irwin, Blake P. Johnson, Roxsan Manshouri, Hesham M. Amin, Joya Chandra

Published Jun 23, 2015 · Vol. 6, No. 27 · pp. 23631-23646

Targeting cancer by binding iron: Dissecting cellular signaling pathways Review

Goldie Y.L. Lui, Zaklina Kovacevic, Vera Richardson, Angelica M. Merlot, Danuta S. Kalinowski, Des R. Richardson

Published Jun 23, 2015 · Vol. 6, No. 22 · pp. 18748-18779

Keywords: cancer, iron, chelators, thiosemicarbazones, signaling, AKT, MAPK, STAT, EMT, autophagy

Androgen receptor splice variants circumvent AR blockade by microtubule-targeting agents Research Paper

Guanyi Zhang, Xichun Liu, Jianzhuo Li, Elisa Ledet, Xavier Alvarez, Yanfeng Qi, Xueqi Fu, Oliver Sartor, Yan Dong, Haitao Zhang

Published Jun 22, 2015 · Vol. 6, No. 27 · pp. 23358-23371

Keywords: androgen receptor, splice variants, prostate cancer, taxane chemotherapy, microtubule

KLF4-SQSTM1/p62-associated prosurvival autophagy contributes to carfilzomib resistance in multiple myeloma models Priority Research Paper

Irene Riz, Teresa S. Hawley, Robert G. Hawley

Published Jun 19, 2015 · Vol. 6, No. 17 · pp. 14814-14831

A MEK/PI3K/HDAC inhibitor combination therapy for KRAS mutant pancreatic cancer cells Priority Research Paper

Irene Ischenko, Oleksi Petrenko, Michael J. Hayman

Published Jun 19, 2015 · Vol. 6, No. 18 · pp. 15814-15827

The endoplasmic reticulum mitochondrial calcium cross talk is downregulated in malignant pleural mesothelioma cells and plays a critical role in apoptosis inhibition Research Paper

Simone Patergnani, Carlotta Giorgi, Stefania Maniero, Sonia Missiroli, Pio Maniscalco, Ilaria Bononi, Fernanda Martini, Giorgio Cavallesco, Mauro Tognon, Paolo Pinton

Published Jun 19, 2015 · Vol. 6, No. 27 · pp. 23427-23444

Keywords: Calcium, mesothelioma, mitochondria, apoptosis, therapy

Chemokines CCL2, 3, 14 stimulate macrophage bone marrow homing, proliferation, and polarization in multiple myeloma Research Paper

Yi Li, Yuhuan Zheng, Tianshu Li, Qiang Wang, Jianfei Qian, Yong Lu, Mingjun Zhang, Enguang Bi, Maojie Yang, Frederic Reu, Qing Yi, Zhen Cai

Published Jun 19, 2015 · Vol. 6, No. 27 · pp. 24218-24229

MicroRNA-153/Nrf-2/GPx1 pathway regulates radiosensitivity and stemness of glioma stem cells via reactive oxygen species Research Paper

Wei Yang, Yueming Shen, Jing Wei, Fenju Liu

Published Jun 18, 2015 · Vol. 6, No. 26 · pp. 22006-22027

Downregulation of c-SRC kinase CSK promotes castration resistant prostate cancer and pinpoints a novel disease subclass Research Paper

Chih-Cheng Yang, Ladan Fazli, Salvatore Loguercio, Irina Zharkikh, Pedro Aza-Blanc, Martin E. Gleave, Dieter A. Wolf

Published Jun 18, 2015 · Vol. 6, No. 26 · pp. 22060-22071

RB1 dual role in proliferation and apoptosis: cell fate control and implications for cancer therapy Review

Paola Indovina, Francesca Pentimalli, Nadia Casini, Immacolata Vocca, Antonio Giordano

Published Jun 18, 2015 · Vol. 6, No. 20 · pp. 17873-17890

Extracellular galectin-3 programs multidrug resistance through Na+/K+-ATPase and P-glycoprotein signaling Research Paper

Yosuke Harazono, Dhong Hyo Kho, Vitaly Balan, Kosei Nakajima, Victor Hogan, Avraham Raz

Published Jun 17, 2015 · Vol. 6, No. 23 · pp. 19592-19604

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CD44 promotes multi-drug resistance by protecting P-glycoprotein from FBXO21-mediated ubiquitination Research Paper

Anti-tumoral effect of desmethylclomipramine in lung cancer stem cells Priority Research Paper

Critical role of Wnt/Î²-catenin signaling in driving epithelial ovarian cancer platinum resistance Research Paper

SERPINA1 is a direct estrogen receptor target gene and a predictor of survival in breast cancer patients Research Paper

Growth arrest DNA damage-inducible gene 45 gamma expression as a prognostic and predictive biomarker in hepatocellular carcinoma Research Paper

Phosphorylation of apoptosis repressor with caspase recruitment domain by protein kinase CK2 contributes to chemotherapy resistance by inhibiting doxorubicin induced apoptosis Research Paper

Folate deficiency-triggered redox pathways confer drug resistance in hepatocellular carcinoma Research Paper

ErbB-3 activation by NRG-1Î² sustains growth and promotes vemurafenib resistance in BRAF-V600E colon cancer stem cells (CSCs) Priority Research Paper

Lovastatin overcomes gefitinib resistance through TNF-α signaling in human cholangiocarcinomas with different LKB1 statuses in vitro and in vivo Research Paper

A NOX2/Egr-1/Fyn pathway delineates new targets for TKI-resistant malignancies Research Paper

Targeting cancer by binding iron: Dissecting cellular signaling pathways Review

Androgen receptor splice variants circumvent AR blockade by microtubule-targeting agents Research Paper

KLF4-SQSTM1/p62-associated prosurvival autophagy contributes to carfilzomib resistance in multiple myeloma models Priority Research Paper

A MEK/PI3K/HDAC inhibitor combination therapy for KRAS mutant pancreatic cancer cells Priority Research Paper

The endoplasmic reticulum mitochondrial calcium cross talk is downregulated in malignant pleural mesothelioma cells and plays a critical role in apoptosis inhibition Research Paper

Chemokines CCL2, 3, 14 stimulate macrophage bone marrow homing, proliferation, and polarization in multiple myeloma Research Paper

MicroRNA-153/Nrf-2/GPx1 pathway regulates radiosensitivity and stemness of glioma stem cells via reactive oxygen species Research Paper

Downregulation of c-SRC kinase CSK promotes castration resistant prostate cancer and pinpoints a novel disease subclass Research Paper

RB1 dual role in proliferation and apoptosis: cell fate control and implications for cancer therapy Review

Extracellular galectin-3 programs multidrug resistance through Na+/K+-ATPase and P-glycoprotein signaling Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

CD44 promotes multi-drug resistance by protecting P-glycoprotein from FBXO21-mediated ubiquitination Research Paper

Anti-tumoral effect of desmethylclomipramine in lung cancer stem cells Priority Research Paper

Critical role of Wnt/Î²-catenin signaling in driving epithelial ovarian cancer platinum resistance Research Paper

SERPINA1 is a direct estrogen receptor target gene and a predictor of survival in breast cancer patients Research Paper

Growth arrest DNA damage-inducible gene 45 gamma expression as a prognostic and predictive biomarker in hepatocellular carcinoma Research Paper

Phosphorylation of apoptosis repressor with caspase recruitment domain by protein kinase CK2 contributes to chemotherapy resistance by inhibiting doxorubicin induced apoptosis Research Paper

Folate deficiency-triggered redox pathways confer drug resistance in hepatocellular carcinoma Research Paper

ErbB-3 activation by NRG-1Î² sustains growth and promotes vemurafenib resistance in BRAF-V600E colon cancer stem cells (CSCs) Priority Research Paper

Lovastatin overcomes gefitinib resistance through TNF-α signaling in human cholangiocarcinomas with different LKB1 statuses in vitro and in vivo Research Paper

A NOX2/Egr-1/Fyn pathway delineates new targets for TKI-resistant malignancies Research Paper

Targeting cancer by binding iron: Dissecting cellular signaling pathways Review

Androgen receptor splice variants circumvent AR blockade by microtubule-targeting agents Research Paper

KLF4-SQSTM1/p62-associated prosurvival autophagy contributes to carfilzomib resistance in multiple myeloma models Priority Research Paper

A MEK/PI3K/HDAC inhibitor combination therapy for KRAS mutant pancreatic cancer cells Priority Research Paper

The endoplasmic reticulum mitochondrial calcium cross talk is downregulated in malignant pleural mesothelioma cells and plays a critical role in apoptosis inhibition Research Paper

Chemokines CCL2, 3, 14 stimulate macrophage bone marrow homing, proliferation, and polarization in multiple myeloma Research Paper

MicroRNA-153/Nrf-2/GPx1 pathway regulates radiosensitivity and stemness of glioma stem cells via reactive oxygen species Research Paper

Downregulation of c-SRC kinase CSK promotes castration resistant prostate cancer and pinpoints a novel disease subclass Research Paper

RB1 dual role in proliferation and apoptosis: cell fate control and implications for cancer therapy Review

Extracellular galectin-3 programs multidrug resistance through Na+/K+-ATPase and P-glycoprotein signaling Research Paper