The Oncosearch | Oncotarget

ATRX mRNA expression combined with IDH1/2 mutational status and Ki-67 expression refines the molecular classification of astrocytic tumors: evidence from the whole transcriptome sequencing of 169 samples Research Paper

Jinquan Cai, Pei Yang, Chuanbao Zhang, Wei Zhang, Yanwei Liu, Zhaoshi Bao, Xing Liu, Wenzhong Du, Hongjun Wang, Tao Jiang, Chuanlu Jiang

Published Mar 21, 2014 · Vol. 5, No. 9 · pp. 2551-2561

SLC25A1, or CIC, is a novel transcriptional target of mutant p53 and a negative tumor prognostic marker. Priority Research Paper

Vamsi K. Kolukula, Geetaram Sahu, Anton Wellstein, Olga C. Rodriguez, Anju Preet, Vito Iacobazzi, Gabriella D'Orazi, Chris Albanese, Ferdinando Palmieri, Maria Laura Avantaggiati

Published Mar 16, 2014 · Vol. 5, No. 5 · pp. 1212-1225

MET aberrations and c-MET inhibitors in patients with gastric and esophageal cancers in a phase I unit Research Paper

Denis L. Fontes Jardim, Debora de Melo Gagliato, Gerald S. Falchook, Filip Janku, Ralph Zinner, Jennifer J. Wheler, Vivek Subbiah, Sarina A. Piha-Paul, Siqing Fu, Mariela Blum Murphy, Jaffer Ajani, Chad Tang, Kenneth Hess, Stanley R. Hamilton, Sinchita Roy-Chowdhuri, Razelle Kurzrock, Funda Meric-Bernstam, David S. Hong

Published Mar 16, 2014 · Vol. 5, No. 7 · pp. 1837-1845

Loss of CADM1 expression is associated with poor prognosis and brain metastasis in breast cancer patients Research Paper

Harriet Wikman, Laura Westphal, Felicitas Schmid, Sirkku Pollari, Jolanthe Kropidlowski, Bettina Sielaff-Frimpong, Markus Glatzel, Jakob Matschke, Manfred Westphal, Kristiina Iljin, Heini Huhtala, Luigi Terracciano, Anne Kallioniemi, Guido Sauter, Volkmar MÃ¼ller, Isabell Witzel, Katrin Lamszus, Dirk Kemming, Klaus Pantel

Published Mar 16, 2014 · Vol. 5, No. 10 · pp. 3076-3087

Epigenetic repression of phosphatidylethanolamine N-methyltransferase (PEMT) in BRCA1-mutated breast cancer Research Paper

Da Li, Fang-Fang Bi, Na-Na Chen, Ji-Min Cao, Wu-Ping Sun, Yi-Ming Zhou, Chen Cao, Chun-Yan Li, Qing Yang

Published Feb 27, 2014 · Vol. 5, No. 5 · pp. 1315-1325

A DNA repair pathway score predicts survival in human multiple myeloma: the potential for therapeutic strategy Research Paper

Alboukadel Kassambara, Claire Gourzones-Dmitriev, Surinder Sahota, Thierry RÃ¨me, JÃ©rÃ´me Moreaux, Hartmut Goldschmidt, Angelos Constantinou, Phillipe Pasero, Dirk Hose, Bernard Klein

Published Feb 24, 2014 · Vol. 5, No. 9 · pp. 2487-2498

Keywords: DNA repair, Multiple Myeloma, prognosis

WNT signaling and distant metastasis in colon cancer through transcriptional activity of nuclear Î²-Catenin depend on active PI3K signaling Research Paper

Steffen Ormanns, Jens Neumann, David Horst, Thomas Kirchner, Andreas Jung

Published Feb 19, 2014 · Vol. 5, No. 10 · pp. 2999-3011

Keywords: WNT, Î²-Catenin, PI3K, colon cancer, metastasis

LIF promotes tumorigenesis and metastasis of breast cancer through the AKT-mTOR pathway Research Paper

Xiaoyan Li, Qifeng Yang, Haiyang Yu, Lihua Wu, Yuhan Zhao, Cen Zhang, Xuetian Yue, Zhen Liu, Hao Wu, Bruce G. Haffty, Zhaohui Feng, Wenwei Hu

Published Feb 15, 2014 · Vol. 5, No. 3 · pp. 788-801

Enrichment of circulating melanoma cells (CMCs) using negative selection from patients with metastatic melanoma. Research Paper

Powrnima Joshi, Barbara Jacobs, Adeeb Derakhshan, Lee R. Moore, Paul Elson, Pierre L. Triozzi, Ernest Borden, Maciej Zborowski

Published Feb 3, 2014 · Vol. 5, No. 9 · pp. 2450-2461

Keywords: circulating melanoma cells, CTC, Melan-A, S100B, magnetic separation, negative selection

Roles of neutrophil gelatinase-associated lipocalin (NGAL) in human cancer Research Paper

Saverio Candido, Roberta Maestro, Jerry Polesel, Alessia Catania, Francesca Maira, Santo S. Signorelli, James A. McCubrey, Massimo Libra

Published Feb 1, 2014 · Vol. 5, No. 6 · pp. 1576-1594

Keywords: NGAL, LCN2, Lipocalin 2, mRNA expression, cancer, biomarker, prognostic factor, metastasis, protein expression

microRNA expression profiling identifies a four microRNA signature as a novel diagnostic and prognostic biomarker in triple negative breast cancers Priority Research Paper

Pierluigi Gasparini, Luciano Cascione, Matteo Fassan, Francesca Lovat, Gulnur Guler, Serdar Balci, Cigdem Irkkan, Carl Morrison, Carlo M. Croce, Charles L. Shapiro, Kay Huebner

Published Jan 21, 2014 · Vol. 5, No. 5 · pp. 1174-1184

Keywords: Triple Negative breast cancer, microRNA, five markers, prognosis, treatments, outcome

MicroRNA-17-5p promotes chemotherapeutic drug resistance and tumour metastasis of colorectal cancer by repressing PTEN expression Research Paper

Lekun Fang, Haoran Li, Lei Wang, Jun Hu, Tianru Jin, Jianping Wang, Burton B. Yang

Published Jan 19, 2014 · Vol. 5, No. 10 · pp. 2974-2987

Keywords: microRNA, stem cell, miR-17, colon cancer, drug resistance

Collagen triple helix repeat containing 1 (CTHRC1) acts via ERK-dependent induction of MMP9 to promote invasion of colorectal cancer cells Research Paper

Hee Cheol Kim, Yong Sung Kim, Hyun-Woo Oh, Kwoneel Kim, Sang-Seok Oh, Jong-Tae Kim, Bo Yeon Kim, Seon-Jin Lee, Yong-Kyung Choe, Dong Hyeok Kim, Seok-Hyung Kim, Seoung Wan Chae, Kwang Dong Kim, Hee Gu Lee

Published Jan 18, 2014 · Vol. 5, No. 2 · pp. 519-529

Keywords: CTHRC1, ERK, MMP9, Invasion, Colorectal cancer

WNT-pathway components as predictive markers useful for diagnosis, prevention and therapy in inflammatory bowel disease and sporadic colorectal cancer Research Paper

Annalucia Serafino, Noemi Moroni, Manuela Zonfrillo, Federica Andreola, Luana Mercuri, Giuseppe Nicotera, Joseph Nunziata, Riccardo Ricci, Armando Antinori, Guido Rasi, Pasquale Pierimarchi

Published Jan 11, 2014 · Vol. 5, No. 4 · pp. 978-992

Keywords: Wnt/Î²-catenin pathway, Colorectal carcinogenesis, Inflammatory Bowel Disease, Diagnostic/therapeutic biomarkers, Multiparametric analysis

P-cadherin signals through the laminin receptor Î±6Î²4 integrin to induce stem cell and invasive properties in basal-like breast cancer cells Research Paper

AndrÃ© Filipe Vieira, Ana Sofia Ribeiro, Maria Rita DionÃsio, BÃ¡rbara Sousa, Ana Nobre, AndrÃ© Albergaria, AngÃ©lica Santiago-GÃ³mez, Nuno Mendes, RenÃª Gerhard, Fernando Schmitt, Robert Brian Clarke, Joana Paredes

Published Jan 6, 2014 · Vol. 5, No. 3 · pp. 679-692

Keywords: P-cadherin, Breast cancer, Î±6Î²4 integrin, cancer stem cells, invasion, FAK, Src

Rac1b negatively regulates TGF-Î²1-induced cell motility in pancreatic ductal epithelial cells by suppressing Smad signalling Research Paper

Hendrik Ungefroren, Susanne Sebens, Klaudia Giehl, Ole Helm, Stephanie Groth, Fred Faendrich, Christoph Roecken, Bence Sipos, Hendrik Lehnert, Frank Gieseler

Published Dec 23, 2013 · Vol. 5, No. 1 · pp. 277-290

Keywords: Rac1b, Rac1, Smad, TGF-beta1, pancreatic ductal adenocarcinoma, cell migration

Lymphoid enhancer binding factor-1 (LEF1) expression as a prognostic factor in adult acute promyelocytic leukemia Research Paper

Francesco Albano, Antonella Zagaria, Luisa Anelli, Paola Orsini, Crescenzio F Minervini, Luciana Impera, Paola Casieri, Nicoletta Coccaro, Giuseppina Tota, Claudia Brunetti, Angela Minervini, Domenico Pastore, Paola Carluccio, Anna Mestice, Angelo Cellamare, Giorgina Specchia

Published Dec 19, 2013 · Vol. 5, No. 3 · pp. 649-658

Keywords: acute promyelocytic leukemia, LEF1, prognosis, outcome

A novel Cdk9 inhibitor preferentially targets tumor cells and synergizes with fludarabine Research Paper

Elisabeth Walsby, Guy Pratt, Hao Shao, Abdullah Y. Abbas, Peter M. Fischer, Tracey D. Bradshaw, Paul Brennan, Chris Fegan, Shudong Wang, Chris Pepper

Published Dec 18, 2013 · Vol. 5, No. 2 · pp. 375-385

Keywords: CLL, cdk9, synergy, MCL1

LZTS1 downregulation confers paclitaxel resistance and is associated with worse prognosis in breast cancer Research Paper

Francesca Lovat, Hideshi Ishii, Monica Schiappacassi, Matteo Fassan, Mattia Barbareschi, Enzo Galligioni, Pierluigi Gasparini, Gustavo Baldassarre, Carlo M. Croce, Andrea Vecchione

Published Dec 14, 2013 · Vol. 5, No. 4 · pp. 970-977

Keywords: Lzts1/Fez1, breast cancer, taxanes

The polycomb group protein EZH2 is a novel therapeutic target in tongue cancer Research Paper

Zhongwu li, Yanling Wang, Jing Qiu, Qiang Li, Chunping Yuan, Wei Zhang, Dongmiao Wang, Jinhai Ye, Hongbin Jiang, Jianrong Yang, Jie Cheng

Published Dec 7, 2013 · Vol. 4, No. 12 · pp. 2532-2549

Keywords: tongue squamous cell carcinoma, polycomb complex, EZH2, DZNep

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ATRX mRNA expression combined with IDH1/2 mutational status and Ki-67 expression refines the molecular classification of astrocytic tumors: evidence from the whole transcriptome sequencing of 169 samples Research Paper

SLC25A1, or CIC, is a novel transcriptional target of mutant p53 and a negative tumor prognostic marker. Priority Research Paper

MET aberrations and c-MET inhibitors in patients with gastric and esophageal cancers in a phase I unit Research Paper

Loss of CADM1 expression is associated with poor prognosis and brain metastasis in breast cancer patients Research Paper

Epigenetic repression of phosphatidylethanolamine N-methyltransferase (PEMT) in BRCA1-mutated breast cancer Research Paper

A DNA repair pathway score predicts survival in human multiple myeloma: the potential for therapeutic strategy Research Paper

WNT signaling and distant metastasis in colon cancer through transcriptional activity of nuclear Î²-Catenin depend on active PI3K signaling Research Paper

LIF promotes tumorigenesis and metastasis of breast cancer through the AKT-mTOR pathway Research Paper

Enrichment of circulating melanoma cells (CMCs) using negative selection from patients with metastatic melanoma. Research Paper

Roles of neutrophil gelatinase-associated lipocalin (NGAL) in human cancer Research Paper

microRNA expression profiling identifies a four microRNA signature as a novel diagnostic and prognostic biomarker in triple negative breast cancers Priority Research Paper

MicroRNA-17-5p promotes chemotherapeutic drug resistance and tumour metastasis of colorectal cancer by repressing PTEN expression Research Paper

Collagen triple helix repeat containing 1 (CTHRC1) acts via ERK-dependent induction of MMP9 to promote invasion of colorectal cancer cells Research Paper

WNT-pathway components as predictive markers useful for diagnosis, prevention and therapy in inflammatory bowel disease and sporadic colorectal cancer Research Paper

P-cadherin signals through the laminin receptor Î±6Î²4 integrin to induce stem cell and invasive properties in basal-like breast cancer cells Research Paper

Rac1b negatively regulates TGF-Î²1-induced cell motility in pancreatic ductal epithelial cells by suppressing Smad signalling Research Paper

Lymphoid enhancer binding factor-1 (LEF1) expression as a prognostic factor in adult acute promyelocytic leukemia Research Paper

A novel Cdk9 inhibitor preferentially targets tumor cells and synergizes with fludarabine Research Paper

LZTS1 downregulation confers paclitaxel resistance and is associated with worse prognosis in breast cancer Research Paper

The polycomb group protein EZH2 is a novel therapeutic target in tongue cancer Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

ATRX mRNA expression combined with IDH1/2 mutational status and Ki-67 expression refines the molecular classification of astrocytic tumors: evidence from the whole transcriptome sequencing of 169 samples Research Paper

SLC25A1, or CIC, is a novel transcriptional target of mutant p53 and a negative tumor prognostic marker. Priority Research Paper

MET aberrations and c-MET inhibitors in patients with gastric and esophageal cancers in a phase I unit Research Paper

Loss of CADM1 expression is associated with poor prognosis and brain metastasis in breast cancer patients Research Paper

Epigenetic repression of phosphatidylethanolamine N-methyltransferase (PEMT) in BRCA1-mutated breast cancer Research Paper

A DNA repair pathway score predicts survival in human multiple myeloma: the potential for therapeutic strategy Research Paper

WNT signaling and distant metastasis in colon cancer through transcriptional activity of nuclear Î²-Catenin depend on active PI3K signaling Research Paper

LIF promotes tumorigenesis and metastasis of breast cancer through the AKT-mTOR pathway Research Paper

Enrichment of circulating melanoma cells (CMCs) using negative selection from patients with metastatic melanoma. Research Paper

Roles of neutrophil gelatinase-associated lipocalin (NGAL) in human cancer Research Paper

microRNA expression profiling identifies a four microRNA signature as a novel diagnostic and prognostic biomarker in triple negative breast cancers Priority Research Paper

MicroRNA-17-5p promotes chemotherapeutic drug resistance and tumour metastasis of colorectal cancer by repressing PTEN expression Research Paper

Collagen triple helix repeat containing 1 (CTHRC1) acts via ERK-dependent induction of MMP9 to promote invasion of colorectal cancer cells Research Paper

WNT-pathway components as predictive markers useful for diagnosis, prevention and therapy in inflammatory bowel disease and sporadic colorectal cancer Research Paper

P-cadherin signals through the laminin receptor Î±6Î²4 integrin to induce stem cell and invasive properties in basal-like breast cancer cells Research Paper

Rac1b negatively regulates TGF-Î²1-induced cell motility in pancreatic ductal epithelial cells by suppressing Smad signalling Research Paper

Lymphoid enhancer binding factor-1 (LEF1) expression as a prognostic factor in adult acute promyelocytic leukemia Research Paper

A novel Cdk9 inhibitor preferentially targets tumor cells and synergizes with fludarabine Research Paper

LZTS1 downregulation confers paclitaxel resistance and is associated with worse prognosis in breast cancer Research Paper

The polycomb group protein EZH2 is a novel therapeutic target in tongue cancer Research Paper