The Oncosearch | Oncotarget

TAK1 regulates the tumor microenvironment through inflammatory, angiogenetic and apoptotic signaling cascades Research Paper

Scott A. Scarneo, Kelly W. Yang, Jose R. Roques, Alanna Dai, Liesl S. Eibschutz, Philip Hughes, Timothy A.J. Haystead

Published May 8, 2020 · Vol. 11, No. 21 · pp. 1961-1970

Keywords: TAK1, breast cancer, therapeutic, inflammation

Nucleolin represses transcription of the androgen receptor gene through a G-quadruplex Research Paper

Cindy K. Miranti, Sara Moore, Yongeun Kim, Venkateshwar Reddy Chappeta, Kui Wu, Biswanath De, Vijay Gokhale, Laurence H. Hurley, Elsa M. Reyes-Reyes

Published Apr 26, 2020 · Vol. 11, No. 19 · pp. 1758-1776

Keywords: prostate cancer, androgen receptor, nucleolin, gene repression, G-quadruplex

Inhibition of HAS2 and hyaluronic acid production by 1,25-Dihydroxyvitamin D₃ in breast cancer Research Paper

Carmen J. Narvaez, Erika LaPorta, Samantha Robilotto, Jennifer Liang, JoEllen Welsh

Published Apr 25, 2020 · Vol. 11, No. 30 · pp. 2889-2905

Keywords: vitamin D, hyaluronic acid, hyaluronan synthase, HAS2, breast cancer

An exploratory study of metformin with or without rapamycin as maintenance therapy after induction chemotherapy in patients with metastatic pancreatic adenocarcinoma Priority Research Paper

Katherine M. Bever, Erkut H. Borazanci, Elizabeth A. Thompson, Jennifer N. Durham, Kimberly Pinero, Gayle S. Jameson, Amber Vrana, Meizheng Liu, Cara Wilt, Annie A. Wu, Wei Fu, Hao Wang, Yafu Yin, Jeffrey P. Leal, Ana De Jesus-Acosta, Lei Zheng, Daniel A. Laheru, Daniel D. Von Hoff, Elizabeth M. Jaffee, Jonathan D. Powell, Dung T. Le

Published Apr 23, 2020 · Vol. 11, No. 21 · pp. 1929-1941

Keywords: pancreatic cancer, mTOR inhibition, maintenance therapy, metformin

The human papillomavirus confers radiosensitivity in oropharyngeal cancer cells by enhancing DNA double strand break Research Paper

Mei Zhang, Angela M. Hong

Published Apr 21, 2020 · Vol. 11, No. 16 · pp. 1417-1426

Keywords: radiosensitivity, oropharyngeal cancer, human papillomavirus, double-strand break, radiobiology

Protein phosphatase 1 regulatory subunit 1A regulates cell cycle progression in Ewing sarcoma Research Paper

Wen Luo, Changxin Xu, Sarah Phillips, Aliza Gardenswartz, Jeremy M. Rosenblum, Janet Ayello, Stephen L. Lessnick, Huai-Xiang Hao, Mitchell S. Cairo

Published Apr 16, 2020 · Vol. 11, No. 19 · pp. 1691-1704

Keywords: PPP1R1A, cell cycle control, IGF-1R, metastasis, Ewing sarcoma

Pirfenidone anti-fibrotic effects are partially mediated by the inhibition of MUC1 bioactivation Research Paper

Beatriz Ballester, Javier Milara, Julio Cortijo

Published Apr 14, 2020 · Vol. 11, No. 15 · pp. 1306-1320

Keywords: pirfenidone, idiopathic pulmonary fibrosis, MUC1, transforming growth factor beta-1, fibroblasts

Molecular imaging reveals biodistribution of P-cadherin LP-DART bispecific and trafficking of adoptively transferred T cells in mouse xenograft model Research Paper

Vijay R. Gupta, Adam Root, Timothy Fisher, Rand Norberg, John David, Tracey Clark, Justin Cohen, Chad May, Anand Giddabasappa

Published Apr 14, 2020 · Vol. 11, No. 15 · pp. 1344-1357

Keywords: bispecific antibody, tumor targeting, biodistribution, T cells, molecular imaging

A phase II study of axalimogene filolisbac for patients with previously treated, unresectable, persistent/recurrent loco-regional or metastatic anal cancer Research Paper

Cathy Eng, Marwan Fakih, Manik Amin, Van Morris, Howard S. Hochster, Patrick M. Boland, Hope Uronis

Published Apr 14, 2020 · Vol. 11, No. 15 · pp. 1334-1343

Keywords: anal neoplasms, immunotherapy, Listeria monocytogenes, papillomaviridae, phase II clinical trial

Zebrafish B cell acute lymphoblastic leukemia: new findings in an old model Research Perspective

Gilseung Park, Jessica Burroughs-Garcia, Clay A. Foster, Ameera Hasan, Chiara Borga, J. Kimble Frazer

Published Apr 14, 2020 · Vol. 11, No. 15 · pp. 1292-1305

Keywords: acute lymphoblastic leukemia, ALL, zebrafish, lymphocyte, MYC

Proteomic analysis of combined IGF1 receptor targeted therapy and chemotherapy identifies signatures associated with survival in breast cancer patients Research Paper

Tali Sinai-Livne, Metsada Pasmanik-Chor, Zoya Cohen, Ilan Tsarfaty, Haim Werner, Raanan Berger

Published Apr 13, 2020 · Vol. 11, No. 17 · pp. 1515-1530

Keywords: insulin-like growth factor-1 (IGF1), IGF1 receptor (IGF1R), targeted therapy, breast cancer, proteomic analysis

Radiation induces iatrogenic immunosuppression by indirectly affecting hematopoiesis in bone marrow Research Paper

Vaishali Kapoor, Andrea Collins, Kaylan Griffith, Subhajit Ghosh, Nathan Wong, Xiaowei Wang, Grant A. Challen, Joseph Krambs, Dan Link, Dennis E. Hallahan, Dinesh Thotala

Published Apr 13, 2020 · Vol. 11, No. 19 · pp. 1681-1690

Keywords: radiation, lymphopenia, mass cytometry RNA sequencing

Correction: Characteristic analysis of TCR β-chain CDR3 repertoire for preand post-liver transplantation Correction

Guiqi Yang, Minglin Ou, Huaizhou Chen, Changchun Guo, Jiejing Chen, Hua Lin, Donge Tang, Wen Xue, Wenlong Li, Weiguo Sui, Yong Dai

Published Apr 7, 2020 · Vol. 11, No. 18 · pp. 1679-1679

Quinacrine inhibits GSTA1 activity and induces apoptosis through G₁/S arrest and generation of ROS in human non-small cell lung cancer cell lines Research Paper

Makhan Kumar, Ansie Martin, Snehal Nirgude, Bibha Chaudhary, Sukanta Mondal, Angshuman Sarkar

Published Apr 6, 2020 · Vol. 11, No. 18 · pp. 1603-1617

Keywords: quinacrine, NSCLC, RhoGTPases, apoptosis, cell cycle

Exosome-mediated delivery of miR-30a sensitize cisplatin-resistant variant of oral squamous carcinoma cells via modulating Beclin1 and Bcl2 Research Paper

Bhagyashri Kulkarni, Piyush Gondaliya, Prathibha Kirave, Rakesh Rawal, Alok Jain, Rachana Garg, Kiran Kalia

Published Apr 2, 2020 · Vol. 11, No. 20 · pp. 1832-1845

Keywords: chemoresistance, miRNA30a-5p, exosomes, oral cancer, autophagy

Investigation of the role of VHL-HIF signaling in DNA repair and apoptosis in zebrafish Research Paper

Hyejeong Rosemary Kim, Kirankumar Santhakumar, Eleanor Markham, Davide Baldera, David Greenald, Helen E. Bryant, Sherif F. El-Khamisy, Fredericus J. van Eeden

Published Mar 31, 2020 · Vol. 11, No. 13 · pp. 1109-1130

Keywords: Hif, Vhl, DNA repair, apoptosis, chemo/radio-resistance

Pineal gland protects against chemically induced oral carcinogenesis and inhibits tumor progression in rats Research Paper

Giseli Mitsuy Kayahara, Vitor Bonetti Valente, Rosani Belzunces Pereira, Felipe Yudi Kabeya Lopes, Marcelo Macedo Crivelini, Glauco Issamu Miyahara, Éder Ricardo Biasoli, Sandra Helena Penha Oliveira, Daniel Galera Bernabé

Published Mar 28, 2020 · Vol. 11, No. 20 · pp. 1816-1831

Keywords: melatonin, cancer, oral cancer, carcinogenesis, pineal gland

Entinostat augments NK cell functions via epigenetic upregulation of IFIT1-STING-STAT4 pathway Research Paper

John M. Idso, Shunhua Lao, Nathan J. Schloemer, Jeffrey Knipstein, Robert Burns, Monica S. Thakar, Subramaniam Malarkannan

Published Mar 25, 2020 · Vol. 11, No. 20 · pp. 1799-1815

Keywords: NK cells, histone deacetylase inhibitor, Ewing sarcoma, rhabdomyosarcoma, immunotherapy

Roscovitine enhances all-trans retinoic acid (ATRA)-induced nuclear enrichment of an ensemble of activated signaling molecules and augments ATRA-induced myeloid cell differentiation Research Paper

Asif Rashid, Xin Duan, Feng Gao, Mengsu Yang, Andrew Yen

Published Mar 24, 2020 · Vol. 11, No. 12 · pp. 1017-1036

Keywords: ATRA, roscovitine, APL, HL-60, Lyn

Combined inhibition of PIM and CDK4/6 suppresses both mTOR signaling and Rb phosphorylation and potentiates PI3K inhibition in cancer cells Priority Research Paper

Lacey M. Litchfield, Karsten Boehnke, Manisha Brahmachary, Cecilia Mur, Chen Bi, Jennifer R. Stephens, J. Michael Sauder, Sonia M. Gutiérrez, Ann M. McNulty, Xiang S. Ye, Wenjuan Wu, María José Lallena, Xueqian Gong, Farhana F. Merzoug, Valerie M. Jansen, Sean G. Buchanan

Published Mar 23, 2020 · Vol. 11, No. 17 · pp. 1478-1492

Keywords: abemaciclib, CDK4/6, PIM, mTOR, S6

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TAK1 regulates the tumor microenvironment through inflammatory, angiogenetic and apoptotic signaling cascades Research Paper

Nucleolin represses transcription of the androgen receptor gene through a G-quadruplex Research Paper

Inhibition of HAS2 and hyaluronic acid production by 1,25-Dihydroxyvitamin D₃ in breast cancer Research Paper

An exploratory study of metformin with or without rapamycin as maintenance therapy after induction chemotherapy in patients with metastatic pancreatic adenocarcinoma Priority Research Paper

The human papillomavirus confers radiosensitivity in oropharyngeal cancer cells by enhancing DNA double strand break Research Paper

Protein phosphatase 1 regulatory subunit 1A regulates cell cycle progression in Ewing sarcoma Research Paper

Pirfenidone anti-fibrotic effects are partially mediated by the inhibition of MUC1 bioactivation Research Paper

Molecular imaging reveals biodistribution of P-cadherin LP-DART bispecific and trafficking of adoptively transferred T cells in mouse xenograft model Research Paper

A phase II study of axalimogene filolisbac for patients with previously treated, unresectable, persistent/recurrent loco-regional or metastatic anal cancer Research Paper

Zebrafish B cell acute lymphoblastic leukemia: new findings in an old model Research Perspective

Proteomic analysis of combined IGF1 receptor targeted therapy and chemotherapy identifies signatures associated with survival in breast cancer patients Research Paper

Radiation induces iatrogenic immunosuppression by indirectly affecting hematopoiesis in bone marrow Research Paper

Correction: Characteristic analysis of TCR β-chain CDR3 repertoire for preand post-liver transplantation Correction

Quinacrine inhibits GSTA1 activity and induces apoptosis through G₁/S arrest and generation of ROS in human non-small cell lung cancer cell lines Research Paper

Exosome-mediated delivery of miR-30a sensitize cisplatin-resistant variant of oral squamous carcinoma cells via modulating Beclin1 and Bcl2 Research Paper

Investigation of the role of VHL-HIF signaling in DNA repair and apoptosis in zebrafish Research Paper

Pineal gland protects against chemically induced oral carcinogenesis and inhibits tumor progression in rats Research Paper

Entinostat augments NK cell functions via epigenetic upregulation of IFIT1-STING-STAT4 pathway Research Paper

Roscovitine enhances all-trans retinoic acid (ATRA)-induced nuclear enrichment of an ensemble of activated signaling molecules and augments ATRA-induced myeloid cell differentiation Research Paper

Combined inhibition of PIM and CDK4/6 suppresses both mTOR signaling and Rb phosphorylation and potentiates PI3K inhibition in cancer cells Priority Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

TAK1 regulates the tumor microenvironment through inflammatory, angiogenetic and apoptotic signaling cascades Research Paper

Nucleolin represses transcription of the androgen receptor gene through a G-quadruplex Research Paper

Inhibition of HAS2 and hyaluronic acid production by 1,25-Dihydroxyvitamin D3 in breast cancer Research Paper

An exploratory study of metformin with or without rapamycin as maintenance therapy after induction chemotherapy in patients with metastatic pancreatic adenocarcinoma Priority Research Paper

The human papillomavirus confers radiosensitivity in oropharyngeal cancer cells by enhancing DNA double strand break Research Paper

Protein phosphatase 1 regulatory subunit 1A regulates cell cycle progression in Ewing sarcoma Research Paper

Pirfenidone anti-fibrotic effects are partially mediated by the inhibition of MUC1 bioactivation Research Paper

Molecular imaging reveals biodistribution of P-cadherin LP-DART bispecific and trafficking of adoptively transferred T cells in mouse xenograft model Research Paper

A phase II study of axalimogene filolisbac for patients with previously treated, unresectable, persistent/recurrent loco-regional or metastatic anal cancer Research Paper

Zebrafish B cell acute lymphoblastic leukemia: new findings in an old model Research Perspective

Proteomic analysis of combined IGF1 receptor targeted therapy and chemotherapy identifies signatures associated with survival in breast cancer patients Research Paper

Radiation induces iatrogenic immunosuppression by indirectly affecting hematopoiesis in bone marrow Research Paper

Correction: Characteristic analysis of TCR β-chain CDR3 repertoire for preand post-liver transplantation Correction

Quinacrine inhibits GSTA1 activity and induces apoptosis through G1/S arrest and generation of ROS in human non-small cell lung cancer cell lines Research Paper

Exosome-mediated delivery of miR-30a sensitize cisplatin-resistant variant of oral squamous carcinoma cells via modulating Beclin1 and Bcl2 Research Paper

Investigation of the role of VHL-HIF signaling in DNA repair and apoptosis in zebrafish Research Paper

Pineal gland protects against chemically induced oral carcinogenesis and inhibits tumor progression in rats Research Paper

Entinostat augments NK cell functions via epigenetic upregulation of IFIT1-STING-STAT4 pathway Research Paper

Roscovitine enhances all-trans retinoic acid (ATRA)-induced nuclear enrichment of an ensemble of activated signaling molecules and augments ATRA-induced myeloid cell differentiation Research Paper

Combined inhibition of PIM and CDK4/6 suppresses both mTOR signaling and Rb phosphorylation and potentiates PI3K inhibition in cancer cells Priority Research Paper

Inhibition of HAS2 and hyaluronic acid production by 1,25-Dihydroxyvitamin D₃ in breast cancer Research Paper

Quinacrine inhibits GSTA1 activity and induces apoptosis through G₁/S arrest and generation of ROS in human non-small cell lung cancer cell lines Research Paper