The Oncosearch | Oncotarget

IGF-1R, a target of let-7b, mediates crosstalk between IRS-2/Akt and MAPK pathways to promote proliferation of oral squamous cell carcinoma Research Paper

Ling Gao, Xiaolong Wang, Xiaofei Wang, Linmei Zhang, Cui Qiang, Suâ€™e Chang, Wenhao Ren, Shaoming Li, Yang Yang, Dongdong Tong, Cheng Chen, Zongfang Li, Tusheng Song, Keqian Zhi, Chen Huang

Published Mar 21, 2014 · Vol. 5, No. 9 · pp. 2562-2574

SLC25A1, or CIC, is a novel transcriptional target of mutant p53 and a negative tumor prognostic marker. Priority Research Paper

Vamsi K. Kolukula, Geetaram Sahu, Anton Wellstein, Olga C. Rodriguez, Anju Preet, Vito Iacobazzi, Gabriella D'Orazi, Chris Albanese, Ferdinando Palmieri, Maria Laura Avantaggiati

Published Mar 16, 2014 · Vol. 5, No. 5 · pp. 1212-1225

Prostate cancer-derived CCN3 induces M2 macrophage infiltration and contributes to angiogenesis in prostate cancer microenvironment Research Paper

Po-Chun Chen, Hsu-Chen Cheng, John Wang, Shin-Wei Wang, Huai-Ching Tai, Chiao-Wen Lin, Chih-Hsin Tang

Published Feb 4, 2014 · Vol. 5, No. 6 · pp. 1595-1608

Keywords: CCN3, VEGF, Prostate cancer, M2 macrophage, angiogenesis

C-kit induces epithelialâ€“mesenchymal transition and contributes to salivary adenoid cystic cancer progression Research Paper

Ya-ling Tang, Yun-long Fan, Jian Jiang, Kai-de Li, Min Zheng, Wei Chen, Xiang-rui Ma, Ning Geng, Qian-ming Chen, Yu Chen, Xinhua Liang

Published Jan 6, 2014 · Vol. 5, No. 6 · pp. 1491-1501

Keywords: salivary adenoid cystic cancer, epithelialâ€“mesenchymal transition (EMT), c-kit, cancer stem cell, metastasis

Frequent amplification of ORAOV1 gene in esophageal squamous cell cancer promotes an aggressive phenotype via proline metabolism and ROS production Research Paper

Yosuke Togashi, Tokuzo Arao, Hiroki Kato, Kazuko Matsumoto, Masato Terashima, Hidetoshi Hayashi, Marco A. de Velasco, Yoshihiko Fujita, Hideharu Kimura, Takushi Yasuda, Hitoshi Shiozaki, Kazuto Nishio

Published Dec 30, 2013 · Vol. 5, No. 10 · pp. 2962-2973

Keywords: oral cancer overexpressed 1, esophageal squamous cell cancer, pyrroline-5-carboxylate reductase, proline metabolism, reactive oxygen species

The polycomb group protein EZH2 is a novel therapeutic target in tongue cancer Research Paper

Zhongwu li, Yanling Wang, Jing Qiu, Qiang Li, Chunping Yuan, Wei Zhang, Dongmiao Wang, Jinhai Ye, Hongbin Jiang, Jianrong Yang, Jie Cheng

Published Dec 7, 2013 · Vol. 4, No. 12 · pp. 2532-2549

Keywords: tongue squamous cell carcinoma, polycomb complex, EZH2, DZNep

Alterations of immune response of non-small cell lung cancer with Azacytidine Research Paper

John Wrangle, Wei Wang, Alexander Koch, Hariharan Easwaran, Helai P. Mohammad, Xiaoyu Pan, Frank Vendetti, Wim VanCriekinge, Tim DeMeyer, Zhengzong Du, Princy Parsana, Kristen Rodgers, Ray-Whay Yen, Cynthia A. Zahnow, Janis M. Taube, Julie R. Brahmer, Scott S. Tykodi, Keith Easton, Richard D. Carvajal, Peter A. Jones, Peter W. Laird, Daniel J. Weisenberger, Salina Tsai, Rosalyn A. Juergens, Suzanne L. Topalian, Charles M. Rudin, Malcolm V. Brock, Drew Pardoll, Stephen B. Baylin

Published Oct 25, 2013 · Vol. 4, No. 11 · pp. 2067-2079

Dietary restriction-resistant human tumors harboring the PIK3CA-activating mutation H1047R are sensitive to metformin Research Paper

Silvia Cufi, Bruna Corominas-Faja, Eugeni Lopez-Bonet, Rosa Bonavia, Sonia Pernas, Isabel Alvarez Lopez, Joan Dorca, Susana Martinez, Norberto Batista Lopez, Severina Dominguez Martinez, Elisabet Cuyas, Joana Visa, Esther Rodriguez-Gallego, Rosa Quirantes-Pine, Antonio Segura-Carretero, Jorge Joven, Begona Martin-Castillo, Javier A Menendez

Published Aug 21, 2013 · Vol. 4, No. 9 · pp. 1484-1495

Keywords: Metformin, cancer, PI3K, PIK3CA mutations, dietary restriction, calorie restriction, rapamycin

Coordinated Targeting of the EGFR Signaling Axis by MicroRNA-27a* Research Paper

Xiaoli Wu, Mihir K. Bhayani, Cristina T. Dodge, Milena S. Nicoloso, Yunyun Chen, Xiaofeng Yan, Makoto Adachi, Ligy Thomas, Chad E. Galer, Tilahun Jiffar, Curtis R. Pickering, Michael E. Kupferman, Jeffrey N. Myers, George A. Calin, Stephen Y. Lai

Published Aug 6, 2013 · Vol. 4, No. 9 · pp. 1388-1398

Keywords: miRNA EGFR AKT1 mTOR miRNA-27a* miRNA-27a-5p

TRAIL induces apoptosis in oral squamous carcinoma cells: a crosstalk with oncogenic Ras regulated cell surface expression of death receptor 5 Research Paper

Jun-jie Chen, Constantinos M. Mikelis, Yaqin Zhang, J. Silvio Gutkind, Baolin Zhang

Published Feb 23, 2013 · Vol. 4, No. 2 · pp. 206-217

Keywords: oral cancer, TRAIL, death receptors, apoptosis, Ras, oncotarget

Development of an orally-administrative MELK-targeting inhibitor that suppresses the growth of various types of human cancer Research Paper

Suyoun Chung, Hanae Suzuki, Takashi Miyamoto, Naofumi Takamatsu, Ayako Tatsuguchi, Koji Ueda, Kyoko Kijima, Yusuke Nakamura, Yo Matsuo

Published Dec 21, 2012 · Vol. 3, No. 12 · pp. 1629-1640

Keywords: oncogene, drug discovery, kinase inhibitor, cancer stem cell

Circulating tumor-derived mutant mitochondrial DNA: a predictive biomarker of clinical prognosis in human squamous cell carcinoma. Brief Reports

Katsuhiro Uzawa, Takao Baba, Fumihiko Uchida, Masanobu Yamatoji, Atsushi Kasamatsu, Yosuke Sakamoto, Katsunori Ogawara, Masashi Shiiba, Hiroki Bukawa, Hideki Tanzawa

Published Jul 25, 2012 · Vol. 3, No. 7 · pp. 670-677

Keywords: squamous cell carcinoma, mitochondrial DNA, high-resolution melting curve analysis, circulating tumor-derived DNA, prognosis

Mutations in circulating mitochondrial DNA: Cassandra of oral cancer? Editorial

Eugene S. Kandel

Published Jul 24, 2012 · Vol. 3, No. 7 · pp. 664-665

Keywords: mitochondrial DNA, oral cancer, biomarker

Regulation of macroautophagy in ovarian cancer cells in vitro and in vivo by controlling Glucose regulatory protein 78 and AMPK Research Paper

Prabodh K. Kandala, Sanjay K. Srivastava

Published May 6, 2012 · Vol. 3, No. 4 · pp. 435-449

Keywords: DIM, ER Stress, Autophagy, Ovarian cancer, Chemoprevention

Expressions of matrix metalloproteinase-9 (MMP-9), dentin sialophosphoprotein (DSPP), and osteopontin (OPN) at histologically negative surgical margins may predict recurrence of oral squamous cell carcinoma Research Paper

Kalu U. E. Ogbureke, Paul M. Weinberger, Stephen W. Lonney, Li Li, Larry W. Fisher

Published Mar 11, 2012 · Vol. 3, No. 3 · pp. 286-298

Keywords: Oral-cancer, DSPP, BSP, OPN, MMP-3, MMP-9, MMP-2, Tumor-Free Margin

A combination of a ribonucleotide reductase inhibitor and histone deacetylase inhibitors downregulates EGFR and triggers BIM-dependent apoptosis in head and neck cancer Research Paper

Roland H. Stauber, Shirley K. Knauer, Negusse Habtemichael, Carolin Bier, Britta Unruhe, Simona Weisheit, Stephanie Spange, Frank Nonnenmacher, Verena Fetz, Torsten Ginter, Sigrid Reichardt, Claus Liebmann, GÃ¼nter Schneider, Oliver H. KrÃ¤mer

Published Jan 28, 2012 · Vol. 3, No. 1 · pp. 31-43

Keywords: apoptosis, BH3-only protein, chemotherapy, hydroxyurea, oral cancer, therapy resistance, tumor xenograft, valproic acid

Genome-wide analysis discloses reversal of the hypoxia-induced changes of gene expression in colon cancer cells by zinc supplementation Research Paper

Michal Sheffer, Amos J. Simon, Jasmine Jacob-Hirsch, Gideon Rechavi, Eytan Domany, David Givol, Gabriella D'Orazi

Published Dec 24, 2011 · Vol. 2, No. 12 · pp. 1191-1202

Keywords: hypoxia, cobalt, pathway analysis, Principal Component Analysis (PCA), cDNA microarray, colon cancer

Overexpression of TWIST2 correlates with poor prognosis in Head and Neck Squamous Cell Carcinomas Research Paper

Daniela Gasparotto, Jerry Polesel, Alessandra Marzotto, Roberta Colladel, Sara Piccinin, Piergiorgio Modena, Alessandra Grizzo, Sandro Sulfaro, Diego Serraino, Luigi Barzan, Claudio Doglioni, Roberta Maestro

Published Dec 22, 2011 · Vol. 2, No. 12 · pp. 1165-1175

Keywords: TWIST1, TWIST2, SNAI1, SNAI2, EMT, HNSCC

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IGF-1R, a target of let-7b, mediates crosstalk between IRS-2/Akt and MAPK pathways to promote proliferation of oral squamous cell carcinoma Research Paper

SLC25A1, or CIC, is a novel transcriptional target of mutant p53 and a negative tumor prognostic marker. Priority Research Paper

Prostate cancer-derived CCN3 induces M2 macrophage infiltration and contributes to angiogenesis in prostate cancer microenvironment Research Paper

C-kit induces epithelialâ€“mesenchymal transition and contributes to salivary adenoid cystic cancer progression Research Paper

Frequent amplification of ORAOV1 gene in esophageal squamous cell cancer promotes an aggressive phenotype via proline metabolism and ROS production Research Paper

The polycomb group protein EZH2 is a novel therapeutic target in tongue cancer Research Paper

Alterations of immune response of non-small cell lung cancer with Azacytidine Research Paper

Dietary restriction-resistant human tumors harboring the PIK3CA-activating mutation H1047R are sensitive to metformin Research Paper

Coordinated Targeting of the EGFR Signaling Axis by MicroRNA-27a* Research Paper

TRAIL induces apoptosis in oral squamous carcinoma cells: a crosstalk with oncogenic Ras regulated cell surface expression of death receptor 5 Research Paper

Development of an orally-administrative MELK-targeting inhibitor that suppresses the growth of various types of human cancer Research Paper

Circulating tumor-derived mutant mitochondrial DNA: a predictive biomarker of clinical prognosis in human squamous cell carcinoma. Brief Reports

Mutations in circulating mitochondrial DNA: Cassandra of oral cancer? Editorial

Regulation of macroautophagy in ovarian cancer cells in vitro and in vivo by controlling Glucose regulatory protein 78 and AMPK Research Paper

Expressions of matrix metalloproteinase-9 (MMP-9), dentin sialophosphoprotein (DSPP), and osteopontin (OPN) at histologically negative surgical margins may predict recurrence of oral squamous cell carcinoma Research Paper

A combination of a ribonucleotide reductase inhibitor and histone deacetylase inhibitors downregulates EGFR and triggers BIM-dependent apoptosis in head and neck cancer Research Paper

Genome-wide analysis discloses reversal of the hypoxia-induced changes of gene expression in colon cancer cells by zinc supplementation Research Paper

Overexpression of TWIST2 correlates with poor prognosis in Head and Neck Squamous Cell Carcinomas Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

IGF-1R, a target of let-7b, mediates crosstalk between IRS-2/Akt and MAPK pathways to promote proliferation of oral squamous cell carcinoma Research Paper

SLC25A1, or CIC, is a novel transcriptional target of mutant p53 and a negative tumor prognostic marker. Priority Research Paper

Prostate cancer-derived CCN3 induces M2 macrophage infiltration and contributes to angiogenesis in prostate cancer microenvironment Research Paper

C-kit induces epithelialâ€“mesenchymal transition and contributes to salivary adenoid cystic cancer progression Research Paper

Frequent amplification of ORAOV1 gene in esophageal squamous cell cancer promotes an aggressive phenotype via proline metabolism and ROS production Research Paper

The polycomb group protein EZH2 is a novel therapeutic target in tongue cancer Research Paper

Alterations of immune response of non-small cell lung cancer with Azacytidine Research Paper

Dietary restriction-resistant human tumors harboring the PIK3CA-activating mutation H1047R are sensitive to metformin Research Paper

Coordinated Targeting of the EGFR Signaling Axis by MicroRNA-27a* Research Paper

TRAIL induces apoptosis in oral squamous carcinoma cells: a crosstalk with oncogenic Ras regulated cell surface expression of death receptor 5 Research Paper

Development of an orally-administrative MELK-targeting inhibitor that suppresses the growth of various types of human cancer Research Paper

Circulating tumor-derived mutant mitochondrial DNA: a predictive biomarker of clinical prognosis in human squamous cell carcinoma. Brief Reports

Mutations in circulating mitochondrial DNA: Cassandra of oral cancer? Editorial

Regulation of macroautophagy in ovarian cancer cells in vitro and in vivo by controlling Glucose regulatory protein 78 and AMPK Research Paper

Expressions of matrix metalloproteinase-9 (MMP-9), dentin sialophosphoprotein (DSPP), and osteopontin (OPN) at histologically negative surgical margins may predict recurrence of oral squamous cell carcinoma Research Paper

A combination of a ribonucleotide reductase inhibitor and histone deacetylase inhibitors downregulates EGFR and triggers BIM-dependent apoptosis in head and neck cancer Research Paper

Genome-wide analysis discloses reversal of the hypoxia-induced changes of gene expression in colon cancer cells by zinc supplementation Research Paper

Overexpression of TWIST2 correlates with poor prognosis in Head and Neck Squamous Cell Carcinomas Research Paper