The Oncosearch | Oncotarget

Novel chemical library screen identifies naturally occurring plant products that specifically disrupt glioblastoma-endothelial cell interactions Priority Research Paper

Rajarshi Sengupta, Amy Barone, Jayne Marasa, Sara Taylor, Erin Jackson, Nicole M. Warrington, Shyam Rao, Albert H. Kim, Jeffrey R. Leonard, David Piwnica-Worms, Joshua B. Rubin

Published Jul 22, 2015 · Vol. 6, No. 21 · pp. 18282-18292

Methylomics analysis identifies ZNF671 as an epigenetically repressed novel tumor suppressor and a potential non-invasive biomarker for the detection of urothelial carcinoma Research Paper

Chia-Ming Yeh, Pi-Che Chen, Hsiao-Yen Hsieh, Yeong-Chin Jou, Chang-Te Lin, Ming-Hsuan Tsai, Wen-Yu Huang, Yi-Ting Wang, Ru-Inn Lin, Szu-Shan Ch, Chun-Liang Tung, Shu-Fen Wu, De-Ching Chang, Cheng-Huang Shen, Cheng-Da Hsu, Michael W.Y. Chan

Published Jul 22, 2015 · Vol. 6, No. 30 · pp. 29555-29572

H19 non coding RNA-derived miR-675 enhances tumorigenesis and metastasis of breast cancer cells by downregulating c-Cbl and Cbl-b Research Paper

Constance Vennin, Nathalie Spruyt, Fatima Dahmani, Sylvain Julien, FranÃ§ois Bertucci, Pascal Finetti, Thierry Chassat, Roland P. Bourette, Xuefen Le Bourhis, Eric Adriaenssens

Published Jul 22, 2015 · Vol. 6, No. 30 · pp. 29209-29223

Identification and characterization of ANO9 in stage II and III colorectal carcinoma Research Paper

Chunxiang Li, Sanjun Cai, Xishan Wang, Zheng Jiang

Published Jul 22, 2015 · Vol. 6, No. 30 · pp. 29324-29334

Molecular classification of gastric cancer: Towards a pathway-driven targeted therapy Review

Ismael Riquelme, Kathleen Saavedra, Jaime A. Espinoza, Helga Weber, Patricia GarcÃa, Bruno Nervi, Marcelo Garrido, Alejandro H. CorvalÃ¡n, Juan Carlos Roa, Carolina Bizama

Published Jul 22, 2015 · Vol. 6, No. 28 · pp. 24750-24779

The clinical development candidate CCT245737 is an orally active CHK1 inhibitor with preclinical activity in RAS mutant NSCLC and EÂµ-MYC driven B-cell lymphoma Research Paper

Mike I. Walton, Paul D. Eve, Angela Hayes, Alan T. Henley, Melanie R. Valenti, Alexis K. De Haven Brandon, Gary Box, Kathy J. Boxall, Matthew Tall, Karen Swales, Thomas P. Matthews, Tatiana McHardy, Michael Lainchbury, James Osborne, Jill E. Hunter, Neil D. Perkins, G. Wynne Aherne, John C. Reader, Florence I. Raynaud, Suzanne A. Eccles, Ian Collins, Michelle D. Garrett

Published Jul 22, 2015 · Vol. 7, No. 3 · pp. 2329-2342

WT1-mediated repression of the proapoptotic transcription factor ZNF224 is triggered by the BCR-ABL oncogene Research Paper

Giorgia Montano, Karina Vidovic, Chiara Palladino, Elena Cesaro, Gaetano Sodaro, Concetta Quintarelli, Biagio De Angelis, Santa Errichiello, Fabrizio Pane, Paola Izzo, Michela Grosso, Urban Gullberg, Paola Costanzo

Published Jul 22, 2015 · Vol. 6, No. 29 · pp. 28223-28237

Heregulin, a new interactor of the telosome/shelterin complex in human telomeres Priority Research Paper

Javier A. Menendez, Louisa Benboudjema, Luciano Vellon, Miguel A. Rubio, Ingrid Espinoza, Judith Campisi, Ruth Lupu

Published Jul 22, 2015 · Vol. 6, No. 37 · pp. 39408-39421

The sum of gains and losses of genes encoding the protein tyrosine kinase targets predicts response to multi-kinase inhibitor treatment: Characterization, validation, and prognostic value Research Paper

Xiaojun Jiang, Daniel Pissaloux, Christelle De La Fouchardiere, FranÃ§oise Desseigne, Qing Wang, Valery Attignon, Marie-Eve Fondrevelle, Arnaud De La Fouchardiere, Maurice Perol, Philippe Cassier, Christelle Seigne, David Perol, Isabelle Ray-Coquard, Pierre Meeus, Jerome Fayette, Aude Flechon, Axel Le Cesne, Nicolas Penel, Olivier Tredan, Jean-Yves Blay

Published Jul 21, 2015 · Vol. 6, No. 28 · pp. 26388-26399

A novel anti-GD2/4-1BB chimeric antigen receptor triggers neuroblastoma cell killing Research Paper

Malvina Prapa, Sara Caldrer, Carlotta Spano, Marco Bestagno, Giulia Golinelli, Giulia Grisendi, Tiziana Petrachi, Pierfranco Conte, Edwin M Horwitz, Dario Campana, Paolo Paolucci, Massimo Dominici

Published Jul 20, 2015 · Vol. 6, No. 28 · pp. 24884-24894

Development and exploitation of a novel mutant androgen receptor modelling strategy to identify new targets for advanced prostate cancer therapy Research Paper

Daniel Oâ€™Neill, Dominic Jones, Mark Wade, James Grey, Sirintra Nakjang, Wenrui Guo, David Cork, Barry R. Davies, Steve R. Wedge, Craig N. Robson, Luke Gaughan

Published Jul 20, 2015 · Vol. 6, No. 28 · pp. 26029-26040

Keywords: Prostate cancer, Androgen receptor, Mutation, Anti-androgen-resistance, SGK1

Tauroursodeoxycholic acid dampens oncogenic apoptosis induced by endoplasmic reticulum stress during hepatocarcinogen exposure Research Paper

Yves-Paul Vandewynckel, Debby Laukens, Lindsey Devisscher, Annelies Paridaens, Eliene Bogaerts, Xavier Verhelst, Anja Van den Bussche, Sarah Raevens, Christophe Van Steenkiste, Marleen Van Troys, Christophe Ampe, Benedicte Descamps, Chris Vanhove, Olivier Govaere, Anja Geerts, Hans Van Vlierberghe

Published Jul 20, 2015 · Vol. 6, No. 29 · pp. 28011-28025

Keywords: hepatocellular carcinoma, unfolded protein response, inflammation, chemoprevention, chaperone

Leukemia inhibitory factor protects cholangiocarcinoma cells from drug-induced apoptosis via a PI3K/AKT-dependent Mcl-1 activation Research Paper

Stuart Duncan Morton, Massimiliano Cadamuro, Simone Brivio, Marta Vismara, Tommaso Stecca, Marco Massani, NicolÃ² Bassi, Alberto Furlanetto, Ruth Elizabeth Joplin, Annarosa Floreani, Luca Fabris, Mario Strazzabosco

Published Jul 20, 2015 · Vol. 6, No. 28 · pp. 26052-26064

The 26S proteasome is a multifaceted target for anti-cancer therapies Review

Tatyana A. Grigoreva, Vyacheslav G. Tribulovich, Alexander V. Garabadzhiu, Gerry Melino, Nickolai A. Barlev

Published Jul 20, 2015 · Vol. 6, No. 28 · pp. 24733-24749

RUNX2 and TAZ-dependent signaling pathways regulate soluble E-Cadherin levels and tumorsphere formation in breast cancer cells Research Paper

Jessica L. Brusgard, Moran Choe, Saranya Chumsri, Keli Renoud, Alexander D. MacKerell Jr., Marius Sudol, Antonino Passaniti

Published Jul 20, 2015 · Vol. 6, No. 29 · pp. 28132-28150

RTVP-1 promotes mesenchymal transformation of glioma via a STAT-3/IL-6-dependent positive feedback loop Research Paper

Nis David Giladi, Amotz Ziv-Av, Hae Kyung Lee, Susan Finniss, Simona Cazacu, Cunli Xiang, Hiba Ben-Asher, Ana deCarvalho, Tom Mikkelsen, Laila Poisson, Chaya Brodie

Published Jul 18, 2015 · Vol. 6, No. 26 · pp. 22680-22697

Repairing of N-mustard derivative BO-1055 induced DNA damage requires NER, HR, and MGMT-dependent DNA repair mechanisms Research Paper

Ching-Ying Kuo, Wen-Cheng Chou, Chin-Chung Wu, Teng-Song Wong, Rajesh Kakadiya, Te-Chang Lee, Tsann-Long Su, Hui-Chun Wang

Published Jul 17, 2015 · Vol. 6, No. 28 · pp. 25770-25783

ABT-263 induces apoptosis and synergizes with chemotherapy by targeting stemness pathways in esophageal cancer Research Paper

Qiongrong Chen, Shumei Song, Shaozhong Wei, Bin Liu, Soichiro Honjo, Ailing Scott, Jiankang Jin, Lang Ma, Haitao Zhu, Heath D. Skinner, Randy L. Johnson, Jaffer A. Ajani

Published Jul 17, 2015 · Vol. 6, No. 28 · pp. 25883-25896

KLF8 promotes tumorigenesis, invasion and metastasis of colorectal cancer cells by transcriptional activation of FHL2 Research Paper

Qingqing Yan, Wenjing Zhang, Yao Wu, Meiyan Wu, Mengnan Zhang, Xinpeng Shi, Jinjun Zhao, Qingzhen Nan, Ye Chen, Long Wang, Tianming Cheng, Jiachu Li, Yang Bai, Side Liu, Jide Wang

Published Jul 15, 2015 · Vol. 6, No. 28 · pp. 25402-25417

PIWIL1 destabilizes microtubule by suppressing phosphorylation at Ser16 and RLIM-mediated degradation of stathmin1 Research Paper

Chao Li, Xiaoyan Zhou, Jianhui Chen, Yilu Lu, Qianqian Sun, Dachang Tao, Wei Hu, Xulei Zheng, Shasha Bian, Yunqiang Liu, Yongxin Ma

Published Jul 15, 2015 · Vol. 6, No. 29 · pp. 27794-27804

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Novel chemical library screen identifies naturally occurring plant products that specifically disrupt glioblastoma-endothelial cell interactions Priority Research Paper

Methylomics analysis identifies ZNF671 as an epigenetically repressed novel tumor suppressor and a potential non-invasive biomarker for the detection of urothelial carcinoma Research Paper

H19 non coding RNA-derived miR-675 enhances tumorigenesis and metastasis of breast cancer cells by downregulating c-Cbl and Cbl-b Research Paper

Identification and characterization of ANO9 in stage II and III colorectal carcinoma Research Paper

Molecular classification of gastric cancer: Towards a pathway-driven targeted therapy Review

The clinical development candidate CCT245737 is an orally active CHK1 inhibitor with preclinical activity in RAS mutant NSCLC and EÂµ-MYC driven B-cell lymphoma Research Paper

WT1-mediated repression of the proapoptotic transcription factor ZNF224 is triggered by the BCR-ABL oncogene Research Paper

Heregulin, a new interactor of the telosome/shelterin complex in human telomeres Priority Research Paper

The sum of gains and losses of genes encoding the protein tyrosine kinase targets predicts response to multi-kinase inhibitor treatment: Characterization, validation, and prognostic value Research Paper

A novel anti-GD2/4-1BB chimeric antigen receptor triggers neuroblastoma cell killing Research Paper

Development and exploitation of a novel mutant androgen receptor modelling strategy to identify new targets for advanced prostate cancer therapy Research Paper

Tauroursodeoxycholic acid dampens oncogenic apoptosis induced by endoplasmic reticulum stress during hepatocarcinogen exposure Research Paper

Leukemia inhibitory factor protects cholangiocarcinoma cells from drug-induced apoptosis via a PI3K/AKT-dependent Mcl-1 activation Research Paper

The 26S proteasome is a multifaceted target for anti-cancer therapies Review

RUNX2 and TAZ-dependent signaling pathways regulate soluble E-Cadherin levels and tumorsphere formation in breast cancer cells Research Paper

RTVP-1 promotes mesenchymal transformation of glioma via a STAT-3/IL-6-dependent positive feedback loop Research Paper

Repairing of N-mustard derivative BO-1055 induced DNA damage requires NER, HR, and MGMT-dependent DNA repair mechanisms Research Paper

ABT-263 induces apoptosis and synergizes with chemotherapy by targeting stemness pathways in esophageal cancer Research Paper

KLF8 promotes tumorigenesis, invasion and metastasis of colorectal cancer cells by transcriptional activation of FHL2 Research Paper

PIWIL1 destabilizes microtubule by suppressing phosphorylation at Ser16 and RLIM-mediated degradation of stathmin1 Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Novel chemical library screen identifies naturally occurring plant products that specifically disrupt glioblastoma-endothelial cell interactions Priority Research Paper

Methylomics analysis identifies ZNF671 as an epigenetically repressed novel tumor suppressor and a potential non-invasive biomarker for the detection of urothelial carcinoma Research Paper

H19 non coding RNA-derived miR-675 enhances tumorigenesis and metastasis of breast cancer cells by downregulating c-Cbl and Cbl-b Research Paper

Identification and characterization of ANO9 in stage II and III colorectal carcinoma Research Paper

Molecular classification of gastric cancer: Towards a pathway-driven targeted therapy Review

The clinical development candidate CCT245737 is an orally active CHK1 inhibitor with preclinical activity in RAS mutant NSCLC and EÂµ-MYC driven B-cell lymphoma Research Paper

WT1-mediated repression of the proapoptotic transcription factor ZNF224 is triggered by the BCR-ABL oncogene Research Paper

Heregulin, a new interactor of the telosome/shelterin complex in human telomeres Priority Research Paper

The sum of gains and losses of genes encoding the protein tyrosine kinase targets predicts response to multi-kinase inhibitor treatment: Characterization, validation, and prognostic value Research Paper

A novel anti-GD2/4-1BB chimeric antigen receptor triggers neuroblastoma cell killing Research Paper

Development and exploitation of a novel mutant androgen receptor modelling strategy to identify new targets for advanced prostate cancer therapy Research Paper

Tauroursodeoxycholic acid dampens oncogenic apoptosis induced by endoplasmic reticulum stress during hepatocarcinogen exposure Research Paper

Leukemia inhibitory factor protects cholangiocarcinoma cells from drug-induced apoptosis via a PI3K/AKT-dependent Mcl-1 activation Research Paper

The 26S proteasome is a multifaceted target for anti-cancer therapies Review

RUNX2 and TAZ-dependent signaling pathways regulate soluble E-Cadherin levels and tumorsphere formation in breast cancer cells Research Paper

RTVP-1 promotes mesenchymal transformation of glioma via a STAT-3/IL-6-dependent positive feedback loop Research Paper

Repairing of N-mustard derivative BO-1055 induced DNA damage requires NER, HR, and MGMT-dependent DNA repair mechanisms Research Paper

ABT-263 induces apoptosis and synergizes with chemotherapy by targeting stemness pathways in esophageal cancer Research Paper

KLF8 promotes tumorigenesis, invasion and metastasis of colorectal cancer cells by transcriptional activation of FHL2 Research Paper

PIWIL1 destabilizes microtubule by suppressing phosphorylation at Ser16 and RLIM-mediated degradation of stathmin1 Research Paper